Clinical trials: Depression, Anxiety, Stress
Affect (Mental Function), Sleep
Fibre and Mental Wellbeing Feasibility Trial
This feasibility study will explore whether adding an extra 10 grams of fibre to participants' daily diet for two weeks would improve their mental health and wellbeing.
- Conditions
- Affect (Mental Function), Sleep, Anxiety, Stress
- Trial name
- NCT06899607
- Testing
- Fibre arm
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
Health College Students
Effects of VR Tai Chi Intervention on Physical Fitness, Anxiety, Depression and Stress Among College Students in Henan, China
Research indicates a substantial increase in the rates of anxiety, depression and stress among college students (Roy, Biswas, \& Sharma, 2025).
- Trial name
- NCT07854821
- Testing
- Virtual Reality-Assisted Tai Chi Training
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Xin Liu
Parental Stress, Depression
Parental Stress During the COVID-19 Pandemic and Its Association With Depression and Anxiety
This study seeks to investigate the levels of parental stress across different demographic subgroups in the general parental population during the strict social distancing government-initiated non-pharmacological interventions…
- Conditions
- Parental Stress, Depression, Anxiety
- Trial name
- NCT04377074
- Where
- Norway
- Volunteers
- 2,880 people
- Sponsor
- University of Oslo
Obesity and Obesity-related Medical Conditions, Menstrual Pain
Quality of Life Variations Among Adolescent Females Following Virtual Reality Games Approach
to compare the effects of virtual reality games, aerobic exercise, and dietary modifications on Quality of Life among adolescent females.
- Conditions
- Obesity and Obesity-related Medical Conditions, Menstrual Pain, Adolescent Obesity, Body Fat Composition
- Trial name
- NCT06604429
- Testing
- Aerobic exercise, Diet Advice, Virtual reality exercise
- Where
- 3 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Mina Atef Georgui Elias
Psychosomatic Symptoms, Temporomandibular Disorder (TMD)
Psychosomatic Symptoms in Patients With Myofascial Pain and Temporomandibular Joint Dysfunction
Temporomandibular joint disorder poses an intricate etiology. Biomechanical, neuromuscular and psychosocial factors may contribute to the disorder among which psychological and psychosocial disturbances have shown strong direct…
- Trial name
- Psychosomatic (NCT07385781)
- Testing
- Casr
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bahria University
Irritable Bowel Syndrome (IBS), Functional Dyspepsia
Interactive Effects of Early-Life Stress, Diet, and Metabolism on Gastrointestinal Dysfunction With Neuropsychiatric Symptoms
The goal of this observational case-control study is to learn how stressful experiences, dietary habits, and blood nutrient levels are associated with gastrointestinal symptoms and symptoms of depression and anxiety in adults…
- Conditions
- Irritable Bowel Syndrome (IBS), Functional Dyspepsia, Inflammatory Bowel Disease (IBD), Gastroparesis
- Trial name
- NCT07852819
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shandong University
Food Insecurity, Depression
Neonatal Neurodevelopmental Outcomes
The main goal of this research is to help mothers with depression and anxiety to cope and bond with their baby. The next goal is to provide resources to help with household needs like food, rent, or utility assistance, health…
- Conditions
- Food Insecurity, Depression, Anxiety, Stress
- Trial name
- NCT07101757
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Post Traumatic Stress Disorder
Effect of Eye Movement Desensitization and Reprocessing Therapy 2.0 Online Group Protocol
In this study, it will be investigated the efficacy of Eye Movement Desensitization and Reprocessing Therapy 2.0 Online Group Protocol on post-traumatic symptoms compared to control group.
- Trial name
- NCT05596903
- Testing
- EMDR 2.0 group protocol, Mhgap stress module
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Academy of Therapeutic Sciences, Turkey
Anxiety, Depression
The Combination of Pharmacotherapy and Cognitive Behavioral Psychotherapy Under the Recovery Perspective.
The combination of pharmacotherapy and individual cognitive behavioral therapy in a private practice.
- Conditions
- Anxiety, Depression, Obsessive-compulsive Disorder, Personality Disorder
- Trial name
- RAKGEOCBT (NCT06993662)
- Testing
- Group A. The combination of pharmacotherapy and individual cognitive behavioral psychotherapy by anxiety disorders and depression., Group B. The combination of pharmacotherapy and individual cognitive behavioral psychotherapy by PTSD, Group C. The combination of pharmacotherapy and individual cognitive behavioral psychotherapy by obsessive-compulsive disorder.
- Where
- Greece
- Volunteers
- 107 people
- Sponsor
- Rakitzi, Stavroula
Anxiety, Depression
Collaborative Care for Women Veterans
Implementation of Tailored Collaborative Care for Women Veterans (CCWV) was designed to enhance primary care-mental health integration for women Veterans by tailoring services to women Veterans' and providers' needs and providing…
- Conditions
- Anxiety, Depression, Stress Disorders, Post Traumatic
- Trial name
- CCWV (NCT02950961)
- Testing
- Collaborative Care for Women Veterans
- Where
- 3 sites in United States
- Volunteers
- 153 people
- Sponsor
- VA Office of Research and Development
Postpartum Depression, Anxiety
Yoga in the NICU for Parents Study
The purpose of this proposal is to test the efficacy of yoga as a mind and body intervention to decrease stress, anxiety, and depression in parents of critically ill neonates hospitalized in the Seattle Children's and University…
- Conditions
- Postpartum Depression, Anxiety, Depression, Stress Disorder
- Trial name
- YiN (NCT05322161)
- Testing
- yoga classes
- Where
- 2 sites in United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Depression, Posttraumatic Stress Disorder
Evaluation of Outcomes Following Surf Therapy
The current study evaluates psychological and physical health outcomes for active-duty service members following participation in an established surf therapy program.
- Trial name
- NCT02857751
- Testing
- Surf therapy
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Depression Anxiety Disorder, Sleep Quality
Digital Silence and Mental Health
Social media use has been linked to negative mental health outcomes, including increased anxiety, depression, stress, poor sleep quality, and difficulties in emotion regulation.
- Trial name
- NCT07147829
- Testing
- digital detox
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Post Traumatic Stress Disorder, Depression
Acceptance and Commitment Group Therapy for Unaccompanied Minors
Unaccompanied minors (UM) are considered to be a highly vulnerable refugee subgroup. Research has indicated that UM experience traumatic events and consequently develop high levels of psychopathology.
- Conditions
- Post Traumatic Stress Disorder, Depression, Anxiety Disorders
- Trial name
- NCT05218031
- Testing
- Acceptance and Commitment Therapy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Anxiety, Depression
VR Mindfulness Study
This is an exploratory study investigating the use of virtual reality-based guided mindfulness meditation in improving pain, stress, and mood within various clinical populations.
- Conditions
- Anxiety, Depression, Stress, Pain, Acute
- Trial name
- NCT05592782
- Testing
- Virtual Reality Based Mindfulness meditation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Depressive Symptoms, Anxiety
Promoting Maternal Mental Health and Wellbeing in Neonatal Intensive Care
This small randomized pilot study will evaluate feasibility and preliminary outcomes of an audio-delivered mindfulness program to reduce psychological distress for mothers with an infant in neonatal intensive care, as compared…
- Conditions
- Depressive Symptoms, Anxiety, Post-traumatic Stress Symptoms
- Trial name
- NCT03942627
- Testing
- Mindfulness Program, Infant Health Education Program
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Arthritis, Diabetes
Can Mental Health Chatbots Help Chronic Disease Populations?
Past research has shown that patients suffering from chronic health conditions tend to experience high levels of negative mental health symptoms (e.g., depression).
- Conditions
- Arthritis, Diabetes, Depression, Anxiety
- Trial name
- NCT04620668
- Testing
- Wysa
- Where
- Canada
- Volunteers
- 79 people
- Sponsor
- Luke MacNeill
Burnout, Anxiety
Mental Health Outcomes and Variations in Exercise in Residents
The goal of this observational study is to learn about the relationship between physical activity levels and mental health outcomes in French medical residents.
- Conditions
- Burnout, Anxiety, Depression Anxiety Disorder, Physical Activity and Wellbeing
- Trial name
- MOVE-Res (NCT07380074)
- Testing
- Physical Activity and Mental Health Outcomes Assessment
- Where
- France
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Anxiety, Depression
Quality of Dying in the Intensive Care Unit: Validation of the CAESAR Scale
The purpose of the study is to evaluate the quality of the dying process in french ICUs (assessed by the CAESAR scale) and to compare physicians', nurses' and relatives perceptions and experiences, with a one-year follow-up of…
- Conditions
- Anxiety, Depression, Posttraumatic Stress Disorder
- Trial name
- CAESAR (NCT01549197)
- Where
- 47 sites in France
- Volunteers
- 475 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post Traumatic Stress Disorder, Intensive Care Psychiatric Disorder
Early EMDR Following Covid-19 Critical Illness: A Feasibility Trial
Primary objective is to evaluate the feasibility of delivering an online early Eye Movement Desensitisation Reprocessing (EMDR) Recent Traumatic Events Protocol (R-TEP) to patients who have survived Covid-19 related critical…
- Conditions
- Post Traumatic Stress Disorder, Intensive Care Psychiatric Disorder, Anxiety Disorders, Depression
- Trial name
- Cov-EMERALD (NCT04455360)
- Testing
- Eye Movement Desensitisation and Reprocessing Recent traumatic Event Protocol
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
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