Clinical trials: Depression, Anxiety, Stress
Anxiety, Depression
Impact of Information Strategy Based on Booklet on Anxiety in Family in ICU
Anxiety and depression are symptoms frequently met in ICU patients and relatives. Risk factors are known: disease severity, age, gender. Another risk factor is lack of information from the medical staff and nurses.
- Conditions
- Anxiety, Depression, Post-traumatic Stress Disorders
- Trial name
- FAMILLE (NCT01365377)
- Testing
- booklet deliverance and use in the process of daily information
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Post-Traumatic Stress Disorders, Major Depressive Disorder
Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans
Co-occurring post-traumatic stress disorder (PTSD) and major depressive disorder (MDD) is the most common response to trauma; it is associated with poor clinical outcomes and substantial human disability.
- Trial name
- NCT04032301
- Testing
- Ketamine, Normal Saline
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
OCD, Major Depressive Disorder (MDD)
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
This is an observational study which does NOT directly administer a psychedelic substance but rather recruits participants who are already participating in another clinical trial in which they may receive a serotonergic…
- Conditions
- OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer
- Trial name
- NCT06624137
- Testing
- Serotonergic Psychedelic
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Yale University
Psychological, Depression, Anxiety
The Effects of a Life Coaching Seminar on Gratitude and Psychological Well-Being
This study will consist of a randomized experimental group and a control group, In addition to the control and experimental group, there will also be a non-randomized motivated experimental group.
- Conditions
- Psychological, Depression, Anxiety, Psychological Stress, Mental Health Wellness 1
- Trial name
- NCT04172051
- Testing
- Tony Robbins Date with Destiny
- Where
- 3 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Depression, Anxiety
Low Intensity Family Support for Refugees in an LMIC
The rapidly growing scale of humanitarian crises requires new response capabilities geared towards addressing populations with prolonged high vulnerability to mental health consequences and little to no access to mental health…
- Conditions
- Depression, Anxiety, PTSD, Family Dynamics
- Trial name
- NCT03978533
- Testing
- Family Support Group
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Panic Disorder, Social Anxiety Disorder
Evaluation of Primary Care Behavioral Health (PCBH) With the Addition of Self-help CBT - A Randomized Multicenter Trial
In this multicenter study, the investigators want to find out if an addition of an diagnostic assessment and possibility of treatment with guided self-help CBT can increase the treatment effects of PCBH on patient functioning and…
- Conditions
- Panic Disorder, Social Anxiety Disorder, Depression, Hypochondriasis
- Trial name
- KAIROS (NCT04900064)
- Testing
- Brief interventions, Self-help CBT
- Where
- 4 sites in Sweden
- Volunteers
- 1,242 people
- Sponsor
- Linnaeus University
Covid19, Neurocognitive Dysfunction
Long-term Neurocognitive and Psychiatric Consequences in Severe COVID-19 Survivors.
Long-term neurocognitive and psychiatric consequences of COVID-19 remain mostly unknown to date. It has been reported that coronaviruses cause direct central nervous system infection (Needham et al. 2020).
- Trial name
- NPQCOVID (NCT05019300)
- Testing
- Exposure: COVID-19 severity
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Loneliness, Depression
Humanoid Robot vs Treatment as Usual for Loneliness
The investigators are aiming to compare the effects of a humanoid robot intervention to treatment as usual, on loneliness and mental health outcomes in older adults living in long-term care, through an assessor-blinded randomized…
- Conditions
- Loneliness, Depression, Stress, Anxiety
- Trial name
- NCT05423899
- Testing
- Grace Robot, Treatment as Usual
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lady Davis Institute
Posttraumatic Stress Disorder, Somatization
Intervention Through EMDR and CBT With Women Victim of Childhood Sexual Abuse. A Randomized Controlled Trial.
This study evaluates the effectiveness of two types of therapy for the treatment of sexual abuse psychological impact on a sample of Spanish women.
- Conditions
- Posttraumatic Stress Disorder, Somatization, Obsessive-Compulsive Disorder, Depression
- Trial name
- NCT04813224
- Testing
- TRAUMA CENTERED EMDR-BASED TREATMENT and TRAUMA-FOCUSED CBT-BASED TREATMENT
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Internacional de Valencia
Post-traumatic Stress Disorder (PTSD), Anxiety Symptoms
The Impact of Playing Tetris on Migrants' Mental Health
This study examines if playing Tetris prevents the development of Post-traumatic stress disorder or related anxiety and depressive symptoms. The investigators recruit 300 participants in total in Greece and in the Netherlands.
- Conditions
- Post-traumatic Stress Disorder (PTSD), Anxiety Symptoms, Depression Symptoms
- Trial name
- NCT06773338
- Testing
- Tetris, No intervention
- Where
- 2 sites in Greece, Netherlands
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tilburg University
Delirium, Stress Disorders, Post-Traumatic
Sedation Influence on Delirium and Post-traumatic Stress-disorder as a Result of Hospitalization in Intensive Care
The aim of this study is to investigate if sedation of Intensive Care Unit (ICU) patients influences the development of delirium during their ICU stay and if incidences of delirium have an impact on the development of…
- Trial name
- NCT01291368
- Where
- 2 sites in Denmark
- Volunteers
- 248 people
- Sponsor
- University of Aarhus
Depression, Anxiety Disorders
Mood Lifters Online for Graduate Students and Young Professionals
Mood Lifters is a revolutionary mental wellness program that teaches scientifically validated strategies in a supportive group setting.
- Conditions
- Depression, Anxiety Disorders, Mood Disorders, Mental Illness
- Trial name
- NCT05078450
- Testing
- Mood Lifters
- Where
- United States
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Mindfulness Training, Cardiac Resynchronization Therapy Devices
Efficacy of a Mindfulness-Based Intervention in Patients With Cardiovascular Implantable Electronic Device
An implantable cardiac defibrillator (implantable cardioverter-defibrillator; ICD) can effectively improve heart rhythm problems and reduce sudden death, and is widely used in the treatment of high-risk patients with fatal…
- Conditions
- Mindfulness Training, Cardiac Resynchronization Therapy Devices, Resilience, Psychological, Anxiety
- Trial name
- MBI-CIED (NCT06021236)
- Testing
- mindfulness-based intervention, CIED procedure routine care
- Where
- Taiwan
- Volunteers
- 34 people
- Sponsor
- Chien Chih-Yin
Posttraumatic Stress Disorder
Exploring Efficacy of Multi-Mode Cognitive Processing Therapy (CPT) for PTSD
This study is a longitudinal, multicenter, single-blind, two-arm randomized controlled trial designed to evaluate the effectiveness of Multi-Modal Cognitive Processing Therapy (MMCPT) for individuals with posttraumatic stress…
- Trial name
- PTSD (NCT07105345)
- Testing
- Cognitive Processing Therapy (CPT), Treatment as Usual (TAU)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Far Eastern Memorial Hospital
Emotional Regulation, Depression
A Precision Medicine Approach to Target Engagement for Emotion Regulation
The proposed study is designed to first test whether teaching people personalized or standardized emotion regulation skills leads to greater decreases in daily negative emotion intensity.
- Conditions
- Emotional Regulation, Depression, Anxiety, Borderline Personality Disorder
- Trial name
- NCT05651295
- Testing
- Checking the Facts, Opposite to Emotion Action, Mindfulness of Current Emotions
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- Matthew Southward, PhD
Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD)
Validation of the CIDI 5.0 Against the SCID-5 for Lifetime Mental Disorders
The World Health Organization Composite International Diagnostic Interview (CIDI) is a fully structured diagnostic tool designed for lay interviewers to assess the prevalence of mental and substance use disorders.
- Conditions
- Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Posttraumatic Stress Disorder (PTSD)
- Trial name
- NCT07604753
- Testing
- CIDI-5
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Anxiety, Depression
Positive Affect Regulation sKills at Northwestern University
The Positive Affect Regulation sKills (PARK) Course is an online program containing a series of positive emotion skills for individuals experiencing stress and distress as a result of COVID-19 and the return to "normal." The…
- Conditions
- Anxiety, Depression, Social Isolation
- Trial name
- PARK-NU (NCT04367922)
- Testing
- Positive Emotion Skills Course
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Depression, Anxiety
Study of Effectiveness of Mental Health Interventions Among Torture Survivors in Southern Iraq
1. That the psychotherapeutic intervention - Components-Base Interventions (CBI) - is effective in reducing the severity of mental health symptoms experienced by torture survivors in Southern Iraq. 2.
- Conditions
- Depression, Anxiety, Post-Traumatic Stress Disorder
- Trial name
- NCT01177072
- Testing
- Cognitive Processing Therapy, Components-Based Intervention
- Where
- Iraq
- Volunteers
- 342 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Mental Illness
Validation of French PHQ-4 and PC-PTSD-5 Screening Scales
Mental illness is a major public health issue. It affects one in five people, represents the largest expense for health insurance (14%), is the leading cause of years lived with disability, and suicide is the main cause of death…
- Trial name
- DEPSYSTAGE (NCT07396623)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depression, Anxiety
Cognitive Processing Therapy in Syrian Women Exposed to IPV
This study aims to explore the efficacy of cognitive processing therapy (CPT) in treating depression, anxiety, PTSD, and difficulties with emotion regulation in Syrian females who have suffered intimate partner violence (IPV).
- Conditions
- Depression, Anxiety, PTSD
- Trial name
- NCT05674591
- Testing
- Cognitive Processing Therapy (CPT)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
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