Clinical trials: Depression, Endogenous
Antenatal Depression, Major Depressive Disorder
Pilot Study of Personalized Aperiodic Transcranial Alternating Current Stimulation in Antenatal Depression (PandA-tACS)
The purpose of this study is to develop the safety, feasibility, and tolerability of a personalized transcranial alternating current stimulation (tACS) approach in antenatal depression.
- Conditions
- Antenatal Depression, Major Depressive Disorder, Major Depressive Disorder in Pregnancy, Healthy Controls
- Trial name
- PandA-tACS (NCT06979154)
- Testing
- tACS (aperiodic)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Depression, Clinical Depression
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Depression
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records
- Conditions
- Depression, Clinical Depression, Depression, Anxiety, Depression, Postpartum
- Trial name
- NCT04211467
- Testing
- No Intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Arthrogryposis, Craniofacial Abnormalities
Study of Quality of Life in Freeman-Sheldon Syndrome and Related Conditions
Freeman-Sheldon syndrome (FSS) is a rare human neuromusculoskeletal disorder present before birth, involving primarily limb and craniofacial deformities.
- Conditions
- Arthrogryposis, Craniofacial Abnormalities, Posttraumatic Stress Disorder, Depressive Disorder
- Trial name
- FSS-QLS (NCT01307475)
- Testing
- PTSD Checklist-Specific, Modified Flanagan Quality of Life Scale, Center for Epidemiologic Studies Depression Scale
- Where
- 2 sites in United States, Guatemala
- Volunteers
- 6 people
- Sponsor
- Freeman-Sheldon Research Group, Inc.
Depression, Insulin Resistance
Endogenous Opioid Activity and Affective State in Insulin Resistant Women
Insulin resistance, a primary component of the metabolic syndrome, is an escalating phenomenon in the United States, and confers an increased risk of depression and mood disorder, particularly in women.
- Conditions
- Depression, Insulin Resistance, Metabolic Syndrome
- Trial name
- NCT02069379
- Testing
- Metformin
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Major Depressive Disorder
Endogenous Opioid Modulation by Ketamine
Demonstrate the acute effects of ketamine on endogenous µ-opioid neurotransmission in humans.
- Trial name
- NCT03051945
- Testing
- Ketamine Hydrochloride, Normal saline
- Where
- United States
- Sponsor
- University of Utah
BIPOLAR DISORDER
Involvement of the Sodium Pump and Endogenous Digitalis-like Compounds in Bipolar Disorder
This study deals with the possible molecular mechanisms that underlie the etiology of bipolar disorders (BD). Previous studies have implicated Na+, K+-ATPase and endogenous digitalis-like compounds (DLC) in the depressive state…
- Trial name
- NA\K-MANIA (NCT01322113)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hadassah Medical Organization
Depressive Disorder, Endogenous Depression
A Clinical Trial of Fluvoxamine for Melancholia
This study aims at investigating the special effectiveness of antidepressant effect of Fluvoxamine for endogenous depression. The investigators also aim to assess the effect of Fluvoxamine on the multimodal magnetic resonance…
- Conditions
- Depressive Disorder, Endogenous Depression, Melancholia
- Trial name
- NCT04160377
- Testing
- Fluvoxamine
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Lingjiang Li