Clinical trials: Depression
Healthy
A Phase 1 Study To Investigate The Pharmacokinetics, Safety And Tolerability Of CP-601,927 In Healthy Japanese Subjects
This Phase 1 study is the first clinical trial to be conducted in Japanese subjects. The pharmacokinetics, safety and tolerability of single and multiple doses of CP-601,927 will be evaluated in Japanese, healthy, non-smoking…
- Trial name
- NCT01396135
- Testing
- CP-601,927
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pfizer
Depression
Exploratory Study of the Effects of Vortioxetine (Lu AA21004) on Cognition and Blood Oxygen Level Dependent (BOLD) Functional Magnetic Resonance Imaging (fMRI) Signals in Subjects Remitted From Depression and in Controls
The purpose of this study is to determine if Vortioxetine 20 mg/day will lead to changes in neural activity (BOLD signal), as measured using fMRI, in brain areas associated with executive functioning and memory during cognitive…
- Trial name
- NCT01607125
- Testing
- Vortioxetine (Lu AA21004)
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Pregnancy Related, Mediation
Investigation of the Effect of Mindfulness-Based Stress Reduction Program on in Pregnant Women
This study was planned to examine the effects of the Mindfulness-Based Stress Reduction Program, which is one of the popular concepts of the 21st century, on depression, psychological well-being and prenatal attachment, which are…
- Conditions
- Pregnancy Related, Mediation, Depression, Maternal-Fetal Relations
- Trial name
- NCT05804838
- Testing
- Mindfulness stress reduction program group
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Anxiety, Depression
Detecting and Evaluating Childhood and Anxiety and Depression Effectively in Subspecialties
The DECADES trial seeks to determine the comparative effectiveness of specialist-centered management of anxiety and depression vs.
- Trial name
- DECADES (NCT02773706)
- Testing
- Automated Psychology Services, Notification of Subspecialist
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Indiana University
Type 2 Diabetes Mellitus (T2DM)
GMVs in Primary Care: An RCT of Group-Based Versus Individual Appointments to Reduce HbA1c in Older People
Type 2 diabetes is a major problem of older people; its prevalence is greater than 20% in those aged over 65 years. Treatment such as medication, healthy nutritional choices \& body weight management, as well as physical activity…
- Trial name
- GAP (NCT02002143)
- Testing
- Group Appointments, Individual Appointments (IAs)
- Where
- 2 sites in Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Depressive Symptoms, Mental Health Wellness 1
Mindfulness and Intercare Based Intervention for Medicine Students (MIIM)
The effects of Coronavirus Disease (COVID-19) pandemic on health, economy and social network has an impact on mental health, specially students.
- Conditions
- Depressive Symptoms, Mental Health Wellness 1, Anxiety
- Trial name
- MIIM (NCT05011955)
- Testing
- Mindfulness, compassion and intercare based Intervention, Psychoeducational based intervention, General curricular intervention
- Where
- Chile
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University Diego Portales
Regular Physical Activity, Exercise
Investigation of the Effectiveness of Regular Physical Activity in University Students
In our study, university students who coded the course from various faculties and departments within the scope of a university-wide free elective course, after regular physical activity; It was aimed to examine the effects on…
- Trial name
- NCT06329115
- Testing
- Exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Depression, Postpartum
Evaluation of Access to Screening for Post-partum Depression Via the Postnatal Interview Within 8 Weeks of Birth in Women Who Have Gave Birth at the Troyes Hospital ( DEPRESSIONPP )
Post-partum depression is defined as a depressive disorder with onset of symptoms in the year following childbirth. Several international studies have reported a prevalence of this condition of around pathology of around 15%.
- Trial name
- DEPRESSIONPP (NCT06469476)
- Testing
- depression post partum
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Troyes
Depression
Effectiveness of a Crowdsourced Cognitive Reappraisal Intervention
This study evaluates a web-based, crowdsourcing platform to promote cognitive reappraisal. Half of participants will be granted access to the crowdsourced reappraisal platform.
- Trial name
- NCT02302248
- Testing
- Crowdsourcing reappraisal intervention, Expressive writing intervention
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Depression, Generalized Anxiety Disorder
Electronic Self-management Resource Training for Mental Health
The purpose of this study is to determine whether mental health treatment disengagement may be mitigated by reducing barriers to self-management and enhancing self-management skills.
- Trial name
- eSMART-MH (NCT01304862)
- Testing
- eSMART-MH intervention, Educational videos about healthy living
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Dietary Behavior, Stress
Dietary Plant Hormone and Mental Health
The aim of this cross-sectional online study is to investigate the association between regular feeding behavior and stress, sleep as well as anxiety and depressive symptoms in healthy subjects.
- Conditions
- Dietary Behavior, Stress, Sleep, Depression, Anxiety
- Trial name
- NCT05276479
- Testing
- Anonymous online survey on dietary habits and mental health
- Where
- Switzerland
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- University of Bern
Breast Cancer, Lung Cancer
Developing a Virtual Stress Management Intervention for Spousal/Partnered Caregivers of Solid Tumor Cancer Patients.
This randomized control trial will investigate the ability of an effective stress management psychoeducation program for employed caregivers to mitigate psychological distress and pathophysiology in spousal or partnered…
- Conditions
- Breast Cancer, Lung Cancer, Colon Cancer, Solid Tumor, Adult
- Trial name
- eCare (NCT04739696)
- Testing
- PEPRR, Pep-Pal
- Where
- United States
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Depression, Anxiety, Trauma
Problem Management Plus Mindfulness-informed Legal Education for Addressing Gender-based Violence and Improving Parenting
Gender-based violence and, more specifically, domestic violence is a prevalent problem globally and in Nigeria. Its effect significantly impacts women and also the wellbeing of their families.
- Conditions
- Depression, Anxiety, Trauma, Anxiety, Parenting Intervention
- Trial name
- PM+MiLE (NCT06601023)
- Testing
- Psychosocial intervention
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Teesside University
Adolescent - Emotional Problem, Smoking
TRIAD Project: Qualitative Study of Adolescent Depression and Smoking
It has been shown in the adult literature that smoking is related to depression and visa versa. Not much is known about how this relationship is started or if one perhaps leads to the other.
- Trial name
- NCT00592696
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Drexel University College of Medicine
Major Depressive Disorder, Menopausal Staging and Vasomotor Symptoms (for Females)
Desvenlafaxine Succinate (DVS) for Major Depressive Disorder (MDD) in Midlife Men and Women
The main objective of this study is to characterize a range of brain activation symptoms associated with depression and response to treatment in midlife men and women with MDD, using MRI and functional MRI.
- Trial name
- DVS (NCT00888862)
- Testing
- Desvenlafaxine Succinate
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Typhoid Vaccine on Sleep
Investigating the Effects of Typhoid Vaccine on Sleep in Healthy Volunteers
Research studies have found a relationship between the immune system (how the body reacts to an infection) and the development of depression.
- Trial name
- NCT02628054
- Testing
- Typhoid Vaccine
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Major Depressive Disorder
Neural Circuit Effects of Ketamine in Depression
This project is designed to examine the role of the subgenual anterior cingulate cortex (sgACC) in anhedonia and anxiety in humans with depression, as well as the acute and sustained effects of ketamine on agACC activation and…
- Trial name
- NCT06213324
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Postpartum Depression
Effect of Exercise and Wellness Interventions on Preventing Postpartum Depression
The purpose of this study is to examine the efficacy of the active interventions (exercise or wellness/support intervention) compared to usual care on the prevention of postpartum depression among women at risk for depression.
- Trial name
- HM2 (NCT01883479)
- Testing
- Exercise, Wellness/Support
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Telerehabilitation, Chair-based Yoga
The Effects of Telerehabilitation And Chair-based Yoga In The Elderly
The aim of the study is to investigate the effects of chair-based yoga with rehabilitation on quality of life is affected in elderly people.
- Conditions
- Telerehabilitation, Chair-based Yoga, Elderly People
- Trial name
- NCT05598554
- Testing
- Telerehabilitation, information
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sevval Kadriye Bakir
Depression, Anxiety, Healthy
Integrins and Protocadherins in Glutamatergic Circuits: Identification of Common Signaling Pathways and Molecular Targets in Anxiety and Major Depressive Disorders (GAPsy)
The aim of this study is to identify biologically viable targets for the treatment of major depressive disorder (MDD) and anxiety disorder (AD) with the ultimate goal of guiding physicians' therapeutic strategies and identifying…
- Trial name
- GAPsy (NCT06167590)
- Testing
- GAPsy protocol
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
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