Clinical trials: Depression
Long COVID
Evaluating the Effects of a Fermented Diet on Microbiome Diversity in Individuals With Long COVID
The purpose of this study is to evaluate the effects of fermented foods on bacterial gut microbiome diversity of long-COVID subjects.
- Trial name
- NCT06560554
- Testing
- Fermented foods, Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Depression
Addressing Mental Health in African American Job Training Adolescents and Young Adults
This project's focus is twofold-to change the culture of an employment training program for adolescents and young adults (Youth Opportunities, or "YO") to more fully address the many mental health issues faced by its participants…
- Trial name
- NCT00979524
- Testing
- Comprehensive Mental Health Services and Supports
- Where
- United States
- Volunteers
- 782 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Major Depression, Bipolar Disorder
Longitudinal Study of People Presenting for First Treatment of a Mood Disorder
The goal of this project is to study the course and outcome of illness in individuals who present with a first episode of depression or mania, or who have a recurrent disorder but have never received treatment.
- Trial name
- NCT01529905
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- McMaster University
Depression, Sleep Disorders, Circadian Rhythm
Longitudinal Ecological Study on Sleep-Wake Patterns in MDD Using Actigraphy
The proposed study will include a longitudinal ecological study (Study 1) and a randomised controlled trial (Study 2). The aims will be to (1) identify the sleep-wake profiles in individuals with Major Depressive Disorder (MDD)…
- Trial name
- NCT06233422
- Testing
- No intervention involved
- Where
- Hong Kong
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Posttraumatic Stress Disorder, PTSD
TDCS-Augmented Prolonged Exposure Therapy
The purpose of this study is to determine the effects of a brain stimulation technique known as transcranial direct current stimulation, or tDCS, on the benefits of Prolonged Exposure therapy, or PE, which is an effective…
- Conditions
- Posttraumatic Stress Disorder, PTSD, Anxiety, Depression
- Trial name
- NCT04327362
- Testing
- Transcranial Direct Current Stimulation (tDCS), Prolonged Exposure Therapy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Depression
Study of the Effects of an Antidepressant Medication and Placebo on the Brain Functioning of Normal Subjects
This study examines the effects of an antidepressant medication and placebo on the brain functioning of normal subjects. In this study, recordings of brain electrical activity are being used to detect and monitor the response to…
- Trial name
- NCT00634283
- Testing
- venlafaxine
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Depression
Major Depression and Inflammatory Risk Markers for Coronary Heart Disease
The overall purpose of this research is to examine whether depression influences immune system function. Studies indicate that individuals who are depressed experience coronary heart disease at a higher rate than expected.
- Trial name
- NCT00037505
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Intolerance of Uncertainty, Anxiety
Test of Target Engagement of Ambiguity Aversion
The present work aims to test whether a single session intervention alters ambiguity aversion, both in terms of people's decision making and their brain responses to ambiguous choices.
- Conditions
- Intolerance of Uncertainty, Anxiety, Intolerance of Uncertainty; Anxiety, Depression, Anxiety
- Trial name
- NCT06962527
- Testing
- Uncertainty-focused single session intervention, Maintaining a healthy lifestyle single session intervention
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Depression and Suicide Ideation
Development and Feasibility of a Metaverse-based Blended Online Intervention to Prevent Employees' Depression
The goal of this feasibility study is to develop a new metaverse-based blended online intervention using an online program and coaching via metaverse to prevent depression among Generation MZ Employees in South Korea.
- Trial name
- NCT06426342
- Testing
- metaverse-based blended online intervention
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University
Brain Function, Ultrasound
Effects of Infra- and Ultrasound on the Brain
Findings in neuroscientific research show that the environment one lives in has measurable effects on brain morphology and functioning.
- Conditions
- Brain Function, Ultrasound, Cognitive Function, Well-being
- Trial name
- NCT03459183
- Testing
- Infrasound (85 dB; 6Hz) source, Ultrasound (10dB below hearing threshold; 22.4 kHz) source, Infrasound dummy source
- Where
- Germany
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Burning Mouth Syndrome, Quality of Life
Effect to the Photobiomodulation in the Burning Mouth Syndrome
Introduction: Burning mouth syndrome (BMS) is a pathology with a low prevalence, affecting between 0.1% and 3.7% of the general population, the ratio between women and men is between 3 and 7:1.
- Conditions
- Burning Mouth Syndrome, Quality of Life, Anxiety Depression, Dry Mouth
- Trial name
- PBM-BMS (NCT05871580)
- Testing
- Low frequency laser activated photobiomodulation, Low frequency laser photobiomodulation inactive
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Mental Illness, Schizophrenia
Measuring Beliefs and Norms About Persons With Mental Illness
Survey experiment to estimate drivers of mental illness stigma
- Conditions
- Mental Illness, Schizophrenia, Bipolar Disorder, Depression
- Trial name
- NCT03656770
- Testing
- Survey questionnaire
- Where
- Uganda
- Volunteers
- 1,782 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Fibromyalgia, Posttraumatic Stress Disorder
Fibromyalgia in Men Suffering From PTSD
Assessing FM and psychiatric state among PTSD, MDD and healthy participants
- Conditions
- Fibromyalgia, Posttraumatic Stress Disorder, Major Depressive Disorder
- Trial name
- NCT00229294
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Depression
Positive Affect Treatment for Adolescents With Early Life Adversity
Youth exposed to early life adversity (ELA) are known to be at greater risk for depression and suicidality and account for almost half of the youth suffering from psychiatric diseases today.
- Trial name
- PAT4ELA (NCT06273137)
- Testing
- Positive affect treatment, Supportive psychotherapy (SUP)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Cancer, Depression
FOCUS:Families OverComing Under Stress
The FOCUS program (study treatment) is an established evidence-based intervention whose redesign for families and couples dealing with serious and chronic illnesses will provide a creative and promising supplement to the existing…
- Conditions
- Cancer, Depression, PostTraumatic Stress Disorder, Anxiety
- Trial name
- NCT02992405
- Testing
- FOCUS Resilience Enhancement Program, Waitlist (No Study Treatment)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Antenatal Care, Mental Health
The Effects of Antenatal Interventions With Artistic Content Given to Pregnant Women
Aim:This study aimed to evaluate the effects of music listening, laughter therapy, and diary keeping, given as group sessions to pregnant women in the last trimester on mothers' overall mental health and maternal attachment…
- Trial name
- NCT04728256
- Testing
- Laughter therapy+Music listening+Keeping diary
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Schizophrenia, Psychotic Disorders
Study to Evaluate the PK Profiles of LY03010 in Patients With Schizophrenia or Schizoaffective Disorder
This is a randomized, single-dose, open-label, parallel-group study. Patients will undergo the screening evaluations to determine eligibility within 28 days prior to study drug administration.
- Conditions
- Schizophrenia, Psychotic Disorders, Mood Disorders, Schizophrenia Spectrum and Other Psychotic Disorders
- Trial name
- NCT05321602
- Testing
- LY03010 156 mg treatment group, deltoid, LY03010 156 mg treatment group, gluteal, LY03010 351 mg treatment group, deltoid
- Where
- 9 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Luye Pharma Group Ltd.
Pediatric Cancer
Evaluation of the Impact of a Family-Centered Empowerment Program on Self-Efficacy, Self-Esteem, Depression, Anxiety, Stress Level, and Care Skills in Parents of Children With Oncological Problems
This study aims to develop a web-based education program based on family centered empowerment model for parents of children with oncological problems and to evaluate the effect of the program on parents' self-efficacy…
- Trial name
- NCT05181228
- Testing
- Web-Based Education Based on Family-Centered Empowerment Model
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Mersin University
Maltreatment
Reduce Childhood Maltreatment and Promote Development
Background (brief): 1. Burden: The uniqueness of each child is tremendously influenced by interaction between nature and nurture during critical period of brain development that promotes foundation of brain architecture through…
- Trial name
- NCT03031236
- Testing
- Psychosocial stimulation, Cognitive behavioral therapy and positive parenting practice
- Where
- Bangladesh
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Depression, Trauma, Psychological
Early Life Stress and Depression: Molecular and Functional Imaging
Severe childhood adversity accounts for a large portion of psychiatric illness, and an increased risk for major depressive disorder (MDD).
- Trial name
- ELS (NCT04713722)
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
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