Clinical trials: Depression
Depression, Anxiety, PTSD
A Scalable Model for Promoting Functioning and Well-Being Among Veterans With a History of Mental Health Challenges Via Meaningful Social Interactions: Project V-SPEAK!
The goal of this study is to refine and test a strategy for engaging veterans with symptoms of depression and/or anxiety as volunteers to help English language learners (ELLs) improve their speaking skills via structured…
- Trial name
- V-SPEAK! (NCT05506839)
- Testing
- Intervention (videoconferencing)
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Depression
Binaural Beat Music Combined With Rhythmic Photic Stimulation on Depression
Background: Previous studies have suggested that non-pharmacological treatments, such as binaural beat music (BBM) and rhythmic photic stimulation (RPS), may help improve depressive symptoms and enhance quality of life.
- Trial name
- NCT06540157
- Testing
- Binaural Beat Music (BBM) Combined with Rhythmic Photic Stimulation (RPS)
- Where
- Taiwan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Aging, Nursing Homes
Effect of Sunlight Exposure and Outdoor Activities on Depression, Cognition and Quality of Life in the Elderly
Background: The transition to long-term care facility can be a stressful and emotional event for the elderly. The evidences showed that the prevalence of depression and the cognition impairment were higher in the…
- Conditions
- Aging, Nursing Homes, Depression in Old Age, Cognitive Impairment
- Trial name
- NCT03304301
- Testing
- sunlight exposure
- Where
- Taiwan
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Chiayi Christian Hospital
Laughter Therapy, Psychological Well-being
Effect of Laughter Therapy on Breast Cancer Patients
The aim of this study is to examine the effect of laughter therapy applied to breast cancer patients before surgical intervention on distress, depression and psychological well-being of patients.
- Conditions
- Laughter Therapy, Psychological Well-being, Breast Cancer, Distress
- Trial name
- NCT07020962
- Testing
- laughter therapy, routine nursing care
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Stress
Authentic Connections for Nurse Leaders
The purpose of this pilot study is to test the feasibility and outcomes of a supportive group-based intervention, Authentic Connections, to be used for nurse leaders at Mayo Clinic, Rochester, in a collaboration involving faculty…
- Trial name
- NCT03616756
- Testing
- Authentic Connections, Protected time
- Where
- 3 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Human Immunodeficiency Virus, Risk Reduction
Building Mobile HIV Prevention and Mental Health Support in Low-resource Settings
The purpose of this research study is to provide help and support for mental health and human immunodeficiency virus (HIV) risk reduction among Romanian gay and bisexual men.
- Conditions
- Human Immunodeficiency Virus, Risk Reduction, Alcohol Abuse, Depression, Anxiety
- Trial name
- NCT03912753
- Testing
- Comunică, Education Attention Control
- Where
- Romania
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Columbia University
Diabetes, Asthma
Integrated Care (IC) Models for Patient-Centered Outcomes
Multiple chronic conditions (MCC) are widely recognized as the U.S. public health challenge of the 21st century. These physical and behavioral health conditions take a large toll on those living with chronic diseases, including…
- Conditions
- Diabetes, Asthma, Chronic Obstructive Pulmonary Disease, Hypertension
- Trial name
- IC (NCT03451630)
- Testing
- High-Touch, High-Tech, Optimal Discharge Planning
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Stress, Self-Efficacy
Using Life's Essential 8 in Midlife Black Women
This research seeks to improve the Midlife Black Women's Stress Reduction and Wellness Intervention (B-SWELL), a program designed to lower heart disease risk in midlife Black women.
- Conditions
- Stress, Self-Efficacy, Heart Disease Risk Factors, Depression Symptoms
- Trial name
- NCT06707636
- Testing
- Experimental: Black Women's Stress and Wellness (B-SWELL) arm, Active Comparator: Wellness (WE) arm
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Psychological Distress, Post Partum Depression
Impact of Mothers Touch Program on Women's Psychological Functioning
The study investigates the effect of the Mothers Touch program on the psychological well-being of new mothers following 5 weeks of child birth.
- Conditions
- Psychological Distress, Post Partum Depression, Mood
- Trial name
- NCT03703219
- Testing
- Mothers Touch Program
- Where
- India
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- NMP Medical Research Institute
Post-partum Depression
PreParent: Internet-based Digital Tools to Screen for and Prevent Postpartum Depression in Parents-to-be
The goal of this randomized controlled study is to evaluate whether an online intervention that combines psychoeducation and affective cognitive training can help prevent postpartum depression in pregnant women and co-parents who…
- Trial name
- NCT07302165
- Testing
- Online prenatal affective cognitive training
- Where
- Denmark
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Anxiety, Depression
Interventions in Adults With Depressive and Anxious Symptoms
In Portugal, there is an increase in cases of depression (from 6.9% to 9.8%) and anxiety (from 3.5% to 6.5%), among those enrolled in health care centers.
- Trial name
- NCT05099744
- Testing
- Electrostimulation Therapy, Relaxation
- Where
- Portugal
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Minho
Post Menopausal
Effects of Progressive Resistance Training Vasomotor Symptoms in Post Menopausal Women
The study will be a randomized clinical trial and will be conducted in Civil Hospital and Kalsoom Hospital Samundry. This study will be completed in time duration of 10 months after the approval of synopsis.
- Trial name
- NCT06166264
- Testing
- Progressive resistance training, Control group
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Depressive Disorder, Major
Study Evalutating the Pharmacokinetics (PK) and Safety of a Single Dose of Desvenlafaxine Sustained Release (DVS SR)
To assess the initial pharmacokinetic profile of single doses of 25mg and 50 mg of DVS SR to healthy subjects.
- Trial name
- NCT00440427
- Testing
- Desvenlafaxine Sustained Release (DVS SR)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Suicidal Ideations, Suicidal Behaviors
Technology-assisted Methods to Advance Suicide Prevention Among Youth in Colombia
This study will investigate a multi-level approach that applies technology-assisted methods to reduce suicidal thoughts and behaviors (SIB) and promote mental health among Colombian youth: (a) digital platform for youth; (b)…
- Conditions
- Suicidal Ideations, Suicidal Behaviors, Depression, Anxiety, Well-being
- Trial name
- NCT06651554
- Testing
- Digital Platform Intervention
- Where
- Colombia
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Brown University
Hysterectomy, Chronic Pain
Evaluation of Central Sensitization, Fear-Avoidance, and Pain-Pressure Threshold With Chronic Pain After Hysterectomy
Phase 1 (started in July 2019): Central Sensitization Inventory (CSI), Fear-Avoidance Components Scale (FACS), pain-pressure threshold are factors associated with chronic post-hysterectomy pain (CPHP), but a complete…
- Conditions
- Hysterectomy, Chronic Pain, Central Sensitisation, Anxiety Depression
- Trial name
- EPOCH (NCT04014829)
- Testing
- Pain-Pressure Threshold, Mechanical Temporal Summation, Hospital Anxiety and Depression Scale
- Where
- Singapore
- Volunteers
- 436 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Caesarean Section, Mother-Child Relations
Effect of Mother's Push at Cesarean Delivery Mother's PUSHING AT CS A RANDOMIZED CONTROLLED TRIAL
The purpose of this study is to assess the safety and efficacy of the mother's active pushing during cesarean delivery.
- Conditions
- Caesarean Section, Mother-Child Relations, Post Operative Pain, Postpartum Depression
- Trial name
- NCT05520580
- Testing
- Mother's push during CS
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Post Partum Depression
Maternal Mental Health in the Hospital Setting
Perinatal (around the time of birth) mental health disorders are common difficulties of pregnancy. Perinatal depression is made up of major and minor depressive events during pregnancy and the first 12 months after delivery.
- Trial name
- MMH (NCT03777046)
- Testing
- Standard of Care (SOC), SOC with Psychology Therapy (CBT)
- Where
- 2 sites in United States
- Volunteers
- 545 people, healthy volunteers welcome
- Sponsor
- Michelle Lopez
Self-reported Symptoms of Depression
Behavioral Study to Predict the Efficacy of a Self-Help Tool
The study aims to examine whether the investigators can predict, on the level of individual participants who have symptoms of depression, who will benefit more from self-help tools based on principles of behavioral activation vs.
- Trial name
- NCT06631183
- Testing
- Self-help information based on principles of behavioral activation, Self-help information based on principles of cognitive restructuring
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Trustees of Princeton University
Molecular Mechanisms of Pharmacological Action, Depression
Effects of Acute Prucalopride Administration in Healthy Volunteers
This study will investigate whether administration of a single dose of the serotonin receptor subtype 4 (5-HT4) partial agonist prucalopride has effects on emotional processing and non-emotional cognition in healthy volunteers…
- Conditions
- Molecular Mechanisms of Pharmacological Action, Depression, Depressive Disorder, Mood Disorders
- Trial name
- NCT03863366
- Testing
- Prucalopride
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Labor Pain
Immersive Virtual Reality Satisfies the Women in Labor by Distracting Them From Their Labor Pain in Labor on Latent and Active Phase
This is a randomized control study with 42 laboring women allocated to virtual reality intervention and control groups. The objective of this study, to evaluate the effectiveness of immersive virtual reality in laboring women on…
- Trial name
- NCT05032456
- Testing
- Oculus Quest All-in-one VR Gaming Headset (128 GB) VR system
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
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