Clinical trials: Depression
Depression
Major Depressive Disorder (MDD)
The purpose of this study is to assess the effectiveness of systematic screening for depression in high-risk patient participants in everyday clinical practice.
- Trial name
- NCT01662817
- Testing
- Intervention, Control
- Where
- Spain
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Anxiety Depression, Breast Cancer
Acupuncture for Anxiety/Depression in Patients With Breast Cancer
The aim of this study is to evaluate the effects and safety of acupuncture on anxiety and/or depression among patients with breast cancer.
- Conditions
- Anxiety Depression, Breast Cancer, Acupuncture
- Trial name
- NCT07183813
- Testing
- Electroacupuncture group
- Where
- China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Depression, Anxiety
Evaluation of Training Curriculum and Service of Improving Access to Community Therapies
The current study aims to conduct a comprehensive evaluation of a training curriculum designed for teaching low-intensity psychological interventions to bachelor's degree holders, specifically focusing on principles of Acceptance…
- Conditions
- Depression, Anxiety, Mental Health Issue, Stress
- Trial name
- iACT (NCT06111820)
- Testing
- Improving Access to Community Therapies (iACT)
- Where
- 21 sites in China
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Mind Mental Health Hong Kong Limited
Depression, Depressive State
A Study to Compare the Pharmacokinetic Profiles of Etravil® Tablet 10mg and Etravil® Tablet 25mg
To evaluate the pharmacokinetics of single oral dose of Amitriptyline hydrochloride film-coated tablet 10mg \& 25mg
- Conditions
- Depression, Depressive State, Enuresis
- Trial name
- DWETR (NCT01367080)
- Testing
- DWETR10, DWETR25
- Where
- South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Dong Wha Pharmaceutical Co. Ltd.
Physical Activity Levels, Cardiovascular Fitness
Effects of Virtual Reality Exercise on Promoting Physical Activity and Health Among College Students
The purpose of this research is to examine the effectiveness of a 4-week immersive-virtual reality (VR) exercise bike intervention on college students' physiological outcomes (physical activity levels, cardiovascular fitness, and…
- Conditions
- Physical Activity Levels, Cardiovascular Fitness, Body Composition, Situational Motivation
- Trial name
- NCT06902727
- Testing
- VR-based exercise bike, Usual routine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Depression, Generalized Anxiety
The Impact of Information Sources on Mental Health During the COVID-19 Pandemic
Study description: The present study seeks to investigate the impact of various sources of information on psychopathology, and specifically health anxiety, depression, and general anxiety, during the COVID-19 pandemic.
- Conditions
- Depression, Generalized Anxiety, Health Anxiety
- Trial name
- NCT04442360
- Testing
- Prospective study with two measurement points investigating the impact of viral mitigation protocols on mental health
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Stress, Anxiety
Psychological and Physiological Effects of Three-Minute Breathing Space Meditation in UPM Postgraduate Students
Postgraduate students often experience psychological distress linked to academic demands, deadlines, research uncertainty, and financial or social pressures, and international students may face additional adjustment challenges.
- Conditions
- Stress, Anxiety, Depression
- Trial name
- NCT07911020
- Testing
- Three-Minute Breathing Space Meditation, Neutral Audio Attention-Control Activity
- Where
- Malaysia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- ZIRUI LIU
Dementia, Cognitive Impairment
Disease Containment Measures Among Older Adults During the Covid-19 Pandemia
This study will examine which impact lockdown strategies intending to prevent the spread of COVID-19 had on people with cognitive impairment and dementia.
- Conditions
- Dementia, Cognitive Impairment, Depression, Anxiety, Loneliness
- Trial name
- Co-AiT (NCT04792086)
- Where
- Norway
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Norwegian Centre for Ageing and Health
Major Depressive Disorder, Bipolar I and Bipolar II
Microbiome of Depression & Treatment Response to Citalopram
The purpose of this study is to evaluate the feasibility of developing a microbiome probe of depression and to evaluate the microbiome change in a preliminary analysis of treatment response (n=20) vs.
- Trial name
- NCT02330068
- Testing
- citalopram
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Anxiety Generalized, Quality of Life
A Problem Solving Intervention for Hospice Caregivers
Hospice care is conceptualized as quality compassionate care for people facing a life-limiting illness, with services that cover clinical care, pain management, and emotional and spiritual support tailored to patients' and…
- Conditions
- Anxiety Generalized, Quality of Life, Depression
- Trial name
- NCT03712410
- Testing
- PISCES
- Where
- United States
- Volunteers
- 523 people, healthy volunteers welcome
- Sponsor
- George Demiris, PhD
Covid19, Stress
A Study on Prevalence, Protection and Recovery From COVID-19 in Seasoned Yoga Practitioners in Comparison to Age and Gender Matched Controls
The study is a randomized controlled trail with an observational arm and aims at collecting information on the prevalence of COVID 19 infection in seasoned yoga practitioners by comparing it with the prevalence of COVID-19…
- Conditions
- Covid19, Stress, Anxiety Depression
- Trial name
- NCT04498442
- Testing
- Simha Kriya, Reading a Book
- Where
- United States
- Volunteers
- 8,519 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Sleep Disturbance, Cognitive Change
Integrating Systematic Data of Medicine to Explore the Solution for Healthy Aging (ISDHA) Phase 4
This project aims to build up the comprehensive health database of geriatric medicine for middle-aged and elderly people in Taiwan.
- Conditions
- Sleep Disturbance, Cognitive Change, Aging
- Trial name
- NCT07414680
- Where
- 2 sites in Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Mental Health Issue
Effect of a Mental Wellness App on the Mental Wellness of Medical and Nurse Anesthesia Students
Mental health issues and suicide are becoming increasingly common among health care trainees and providers. Suicide is the leading cause of death among male medical residents and the second leading cause of death among female…
- Trial name
- NCT05925062
- Testing
- QActual
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Major Depressive Disorder
Brain Regulation of Emotions in People With Depression and Anhedonia
This study will use magnetic resonance imaging (MRI) to examine how the brain regulates emotions in healthy people and in patients who have major depression and anhedonia (loss of feeling of pleasure in things that normally give…
- Trial name
- NCT00059579
- Where
- United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Premenstrual Dysphoric Disorder
Emotional Processing and Oxytocin Mechanisms in Premenstrual Dysphoric Disorder: A Pilot Study
This research study will look at brain and symptom differences among women with severe premenstrual mood symptoms. One goal of this study is to look at the effects of taking a nasal spray containing oxytocin (a hormone made in…
- Trial name
- NCT02508103
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Depression, Anxiety
Implementation of Brief Dynamic Interpersonal Therapy at the VA
The goal of the proposed project is to collect data from clinician files and the electronic medical record to describe the clinical implementation of Brief Dynamic Interpersonal Therapy (DIT), an individual psychotherapy for…
- Trial name
- DIT (NCT03945136)
- Testing
- Dynamic Interpersonal Therapy
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- VA New York Harbor Healthcare System
Postpartum Depression (PPD)
A Mobile Application for Early Detection and Symptoms Trajectories of Postpartum Depression Using Ecological Momentary Assessment (EMA)
This pilot study will recruit 120 perinatal pregnant women and follow them up for 6 months. Both momentary and retrospective assessments of emotional well-being and psychosocial factors will be conducted on a mobile application.
- Trial name
- EMA For PND (NCT07382336)
- Testing
- Ecological momentary assessment and retrospective assessment
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Depressive Disorder, Major
Peripheral Immunomarker Validation in Treatment-resistant Depression
This is a study to characterise the role of inflammatory processes in depression. There is compelling evidence that inflammation is often associated with, and can cause, depression.
- Trial name
- BIODEP (NCT02752178)
- Testing
- MA, DEP
- Where
- 5 sites in United Kingdom
- Volunteers
- 393 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Major Depression, Dysthymia
Online System for Identifying and Addressing Teen Depression in Primary Care
A novel web-based module (Teen Depression Module or TDM)has been created for assisting primary care providers (PCPs) in screening for and addressing and referring teens with depression.
- Conditions
- Major Depression, Dysthymia, Depressive Symptoms
- Trial name
- Depression (NCT04489485)
- Testing
- Teen Depression Module used for care
- Where
- United States
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- Total Child Health, Inc.
Same-Sex Relationships
Better Together: A Web-based Relationship Education Tool
Health disparities have been documented in same-sex partnered women, including higher rates of cardiovascular disease, Type 2 diabetes, cancers, and mental health disorders.
- Trial name
- NCT03953495
- Testing
- Better Together
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Sharon Scales Rostosky
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