Clinical trials: Depression
Depression Symptoms, Anxiety Symptoms
Developing a Booster Session for Problem Management Plus in the Bahamas: A Pilot Randomized Controlled Trial
Therapists at the Grand Bahama Resilience Center (GBRC) will be trained to deliver Problem Management Plus (PM+), a WHO intervention.
- Trial name
- NCT07208851
- Testing
- Problem Management Plus booster session
- Where
- The Bahamas
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The New School
Major Depressive Disorder
Using Voice Biomarkers to Predict the Likelihood of Major Depressive Disorder
Major Depressive Disorder (MDD) is the leading cause of disability worldwide. Depression and anxiety disorders are among the most prevalent of all mental disorders, with an estimated annual prevalence of 9.7% and 18.1%…
- Trial name
- NCT04874077
- Where
- 2 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Kintsugi Mindful Wellness, Inc.
Psychological Stress, Anxiety
Mindfulness Training in U.S. Army Cohorts
This project aims to contextualize delivery of mindfulness training to U.S. Army personnel, evaluate its effectiveness on measures of executive functions and psychological well-being, and determine best practices for its delivery.
- Conditions
- Psychological Stress, Anxiety, Post Traumatic Stress Disorder, Depression
- Trial name
- NCT03310112
- Testing
- 4-week MBAT, 2-week MBAT
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Miami
Mental Health Issue, Insomnia
Promoting Teenage Sleep for Improved Mental Health and School Performance
The overall aim of this project is to evaluate the effectiveness of two school-based programs that have the potential to promote adolescent sleep and prevent future depressive symptoms.
- Conditions
- Mental Health Issue, Insomnia, Depression, Anxiety
- Trial name
- TeenSleep (NCT06306092)
- Testing
- Sleep on Schedule, Technology restriction
- Where
- Sweden
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Kristianstad University
Major Depressive Disorder
A Pharmacokinetic Study on the Effect of LY2216684 on the Active Metabolite of Clopidogrel
The purpose of this study is to measure how much of the study drugs (clopidogrel and LY2216684) reach the blood stream and how long it takes the body to dispose of them and to determine how clopidogrel and LY2216684 might affect…
- Trial name
- NCT01263093
- Testing
- Clopidogrel, LY2216684
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Mood, Depression
Effect of Daily Vinegar Ingestion for Four Weeks on Mood State in Healthy College Students
The objective of this research is to record mood states and depression levels in healthy college students before and after 4 weeks of daily vinegar ingestion.
- Trial name
- VIN2020 (NCT04706806)
- Testing
- apple cider vinegar, vinegar pill
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Depression
Remote Training in Evidence-based Practices for Clinicians Who Work With Migrant Workers
This study will compare training as usual to automated training using an intelligent tutoring system in training bachelors (BA) level social workers in cognitive behavioral therapy (CBT).
- Trial name
- NCT03515226
- Testing
- ITS based training, Traditional Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Washington
Stress, Depression
Sinasprite: A Pilot Feasibility Study for Patients With Anxiety or Stress
The investigators are proposing a prospective one-arm cohort study testing the feasibility of a game designed to improve symptoms in adults with mild levels of stress, depression, and anxiety.
- Conditions
- Stress, Depression, Anxiety
- Trial name
- NCT02955784
- Testing
- Sinasprite Mobile App
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Chronic Obstructive Pulmonary Disease, End-of-Life Fear
End-of-Life Fear in Patients With End-Stage Lung Disease (COPD)
The aim of the study is to develop an interview to ask patients with COPD about their fear of death and dying, their needs and wishes at the end-of-life.
- Conditions
- Chronic Obstructive Pulmonary Disease, End-of-Life Fear, Fear About Death and Dying, Depression
- Trial name
- NCT00792974
- Testing
- A brief psycho-educational intervention
- Where
- 2 sites in Germany
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Depression, Mental Disorder
Digital Training for Non-Specialist Health Workers to Deliver a Brief Psychological Treatment for Depression
The purpose of this 3-arm randomized controlled trial is to compare two forms of digital training (i.e., low-intensity and high-intensity) with traditional face-to-face training of non-specialist health workers to deliver an…
- Conditions
- Depression, Mental Disorder, Psychological
- Trial name
- ESSENCE (NCT04157816)
- Testing
- Face-to-Face Training, Digital Training, Coaching Support
- Where
- India
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Mood Disorders, Anxiety Disorders
Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers
The purpose of this protocol is to allow for the careful screening of patients and healthy volunteers for participation in research protocols in the Experimental Therapeutics and Pathophysiology Lab (ETPB) at the National…
- Conditions
- Mood Disorders, Anxiety Disorders, Healthy Volunteers, Bipolar Disorder
- Trial name
- NCT00024635
- Where
- United States
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Postpartum Anxiety, Postpartum Depression
Postpartum Screening for Anxiety and Comorbid Conditions
The goal of this project is to facilitate the design of individualized postpartum anxiety (PPA) screening strategies in British Columbia (BC), Canada.
- Conditions
- Postpartum Anxiety, Postpartum Depression, Postpartum Disorder, Postoperative Pain
- Trial name
- PPA (NCT06242717)
- Where
- Canada
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Podcast, Postpartum Woman
The Effect of Podcast Education on Postpartum Depression, Maternal Attachment, and Self-Care Agency in the Early Postpartum Period: A Randomized Controlled Trial
The population of the study, planned as a randomized controlled experimental design, consists of primiparous women who gave birth in the delivery unit of Istanbul Esenler Women's Health and Pediatric Diseases Hospital.
- Trial name
- NCT07460921
- Testing
- Providing discharge education via podcasts
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Major Depressive Disorder
Internet-Based Depression Screening for College Students
This study aims to determine whether using telecommunication tools, specifically web pages containing online screening instruments and real-time video chat, will be an efficient way to implement Major Depressive Disorder…
- Trial name
- NCT01326793
- Testing
- Skype Consultation
- Where
- United States
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Depressive Symptoms, Depression
Efficacy and Safety of Auricular Acupuncture in Depression During the Covid 19 Pandemic
Participants with moderate depressive symptoms measured by PHQ-9 will be randomized to receive auricular acupuncture. The triple blinded procedure will be conducted in 12 sessions (6 weeks).
- Conditions
- Depressive Symptoms, Depression, Anxiety, Insomnia
- Trial name
- NCT05855421
- Testing
- Auricular Acupuncture
- Where
- Brazil
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Universidade do Sul de Santa Catarina
Stress, Anxiety
Comparing the Effects of Mindfulness-Based and Cognitive Behavioral-Based Stress Reduction in Medical Students
We aimed to compare the effects of the Mindfulness-Based Stress Reduction (MBSR) and the Cognitive Behavioural Stress Reduction (CBSR) group interventions on depression and anxiety symptoms and perceived stress of medical…
- Conditions
- Stress, Anxiety, Depressive Symptoms
- Trial name
- NCT06156852
- Testing
- Mindfulness-based stress reduction group, Cognitive behavioral-based stress reduction group
- Where
- Turkey (Türkiye)
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Gazi University
Insomnia, Anxiety
Treating Comorbid Insomnia in Transdiagnostic Internet-Delivered Cognitive Behaviour Therapy
Transdiagnostic Internet-delivered Cognitive Behaviour Therapy (ICBT) is an efficacious treatment option for anxiety and depression; however, not all patients benefit equally and some leave treatment before program completion.
- Conditions
- Insomnia, Anxiety, Depression
- Trial name
- NCT04512768
- Testing
- Transdiagnostic Internet-delivered Cognitive Behaviour Therapy, Brief Internet-Delivered Cognitive Behaviour Therapy for Insomnia
- Where
- Canada
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- University of Regina
Perinatal Depression, Postpartum Depression
Integrating Text Messages Into the Mothers and Babies Course
This project is aimed at enhancing the effectiveness and scalability of the Mothers and Babies 1-on-1 Course (MB) among home visiting programs.
- Trial name
- NCT03420755
- Testing
- Mothers and Babies 1-on-1, Mothers and Babies Plus Text
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Major Depressive Disorder, Sexual Behavior
The Pill Project - Oral Contraceptive and Serotonergic Brain Signaling
Large register based work has shown that starting on oral contraceptives (OCs) is associated with an increased risk of developing depressive episodes.
- Conditions
- Major Depressive Disorder, Sexual Behavior, Mood Disturbance, Mood Change
- Trial name
- NCT05212389
- Testing
- Femicept
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cognition Disorders, Depression
Well-Being in Medical Residents in the HIBA
It is necessary and important to design tools to evaluate a central aspect of medical residents formation. The research group has been working with resident well-being since a few years in order to improve the global quality of…
- Conditions
- Cognition Disorders, Depression, Anxiety, Shift-Work Sleep Disorder
- Trial name
- NCT03087435
- Testing
- Well-Being questionnaire
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
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