Clinical trials: Depression
Perimenopausal Disorder, Depression
Effects of a Tissue Selective Estrogen Complex (TSEC) on Depression and the Neural Reward System in the Perimenopause"
Using neuroimaging, the investigator will study the effects of estrogen on mood and brain function in perimenopausal women with depression.
- Trial name
- Duavee (NCT03740009)
- Testing
- Bazedoxifene/Conjugated Estrogen
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Aged, Loneliness
Effects of a Volunteer-based Lunch Program on Feelings of Loneliness in Elders
Background: There is a need for stronger community involvement with the elderly, specifically those with feelings of loneliness.
- Conditions
- Aged, Loneliness, Depression, Anxiety
- Trial name
- NCT03552328
- Testing
- Lunch with Medical Student, Control
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Postpartum Depression, Maternal-Fetal Relations
Effect of Listening to Surah Al-Inshirah (The Opening-Up of the Heart) After Cesarean Birth on Postpartum Outcomes
This randomized controlled trial aims to evaluate the effect of listening to the recitation of Surah Al-Inshirah during the early postpartum period after cesarean birth on women's spiritual well-being, depression levels, and…
- Conditions
- Postpartum Depression, Maternal-Fetal Relations, Spirituality
- Trial name
- NCT07354334
- Testing
- Listening to Surah Al-Inshirah
- Where
- Turkey (Türkiye)
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Post-partum Depression
Mobile Application in the Management of Mild to Moderate Postpartum Depression (PPD)
Primary Objective: Evaluate the user experience with the Stella (TM) app for the management of Postpartum Depression in an observed population for 8 calendar weeks.
- Trial name
- NCT05077644
- Testing
- Stella (TM) Mobile Application
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Curio Digital Therapeutics, Inc.
Psychological Stress, Perinatal Problems
Kogito: App to Reduce Perinatal Psychosocial Stress
The purpose of this research study is to test the efectivness of the remote solution for psychosocial stress in pregnant women and postpartum women.
- Conditions
- Psychological Stress, Perinatal Problems, Depression, Anxiety
- Trial name
- NCT04876144
- Testing
- Kogito
- Where
- Czechia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health, Czech Republic
Depression, Treatment Resistant Depression
Computational Psychiatric Approach to Depression
The purpose of this research is to investigate how the brain changes in patients undergoing electroconvulsive (ECT) treatment for depression.
- Trial name
- NCT04189939
- Testing
- clinical assessments
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Depression, Anxiety, Self Efficacy
Advocates for All Youth
Advocates for ALLY Youth (ALLY) is a universal, school-based, multicomponent positive psychology program aimed to increase youth's well-being and reduce symptoms of psychological distress including depression, anxiety, and stress.
- Conditions
- Depression, Anxiety, Self Efficacy, Suicidal Ideation
- Trial name
- ALLY (NCT05025657)
- Testing
- ALLY
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Anxiety, Depression
Impact of Complimentary and Alternative Practices on Patient Wellbeing During Rehabilitation
The study's objective is to assess whether CAM methods are feasible and beneficial in the WSRH setting; to assess stress (using the Perceived Stress Scale-14 and using BioSquares™), anxiety (using the Generalized Anxiety…
- Conditions
- Anxiety, Depression, Stress, Pain
- Trial name
- NCT05082246
- Testing
- Conscious Breathing, Heartfulness Meditation, Emotional Freedom Technique
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- WellSpan Health
Depression
Behavioral Activation for Depression: A Randomized Controlled Trial
The present study is a randomized controlled trial that will evaluate two versions of behavioral activation (BA); one version which is a standard BA program and one which is a motor enhanced BA program (mBA).
- Trial name
- NCT04700774
- Testing
- Behavioral activation
- Where
- Denmark
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Schizophrenia, Depression
Characterization of the Motivational Deficit in Schizophrenia and Depression
This research focuses on disorders of motivation, responsible for a disability that patients experience daily. It is a disorder that affects behavior, especially social.
- Trial name
- SCHIZOBAT (NCT02378818)
- Testing
- Force task, preference task, discount task, learning task.
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Depression, Hematopoietic and Lymphoid Cell Neoplasm
Using Technology to Optimize Collaborative Care Management of Depression in Urban and Rural Cancer Centers, SCOPE
This study compares the effectiveness of technology-enhanced collaborative care management (t-CoCM) to usual collaborative care management (u-CoCM) in achieving fidelity to processes of care and reducing depression symptoms in…
- Conditions
- Depression, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT05012124
- Testing
- Collaborative care, Interview or Focus Group, Media/technology Intervention with collaborative care
- Where
- 4 sites in United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- University of Washington
Emotional Well-being
iCBT to Promote Emotional Well-being in University and Research Communities: Feasibility and Acceptability Study
This study will evaluate a brief internet-based cognitive behavioral therapy (iCBT) program developed specifically for university students, researchers, and academic staff.
- Trial name
- iCBT-Academia (NCT07082296)
- Testing
- iCBT-Academia
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Joaquim Radua
Major Depression
Testosterone and Major Depression
Context - As men age, testosterone levels decline leading to symptoms that overlap with the symptoms of major depression. Little is known about the potential role of testosterone in the treatment of major depression.Objective …
- Trial name
- NCT00286546
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Psychological, Burnout
Psychological Support for Intensive Care Nurses During the COVID-19 Pandemic: The PROACTIVE Feasibility Trial
The psychological health of frontline healthcare workers, caring for critically ill patients with COVID-19, has deteriorated during the pandemic. Nurses appear to be most seriously affected.
- Conditions
- Psychological, Burnout, Post Traumatic Stress Disorder, Anxiety
- Trial name
- NCT05087186
- Testing
- Guided imagery and FLASH technique
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Resting Metabolic Rate, Bone Mineral Density, Low, Susceptibility to
The Health of Competitive Fitness Athletes
Fitness athletes emphasize the value of staying lean, muscular and defined, and motivates and inspires followers through social media.
- Conditions
- Resting Metabolic Rate, Bone Mineral Density, Low, Susceptibility to, Body Image, Perfectionism
- Trial name
- NCT03007459
- Testing
- Psychological health, Physiological health
- Where
- Norway
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Respiratory Depression
ENA-001 for Opioid Induced Respiratory Depression
This study is a Phase I clinical trial to assess the safety, tolerability, and pharmacokinetic (PK) and pharmacodynamic (PD) profiles with single intravenous (IV) and intramuscular (IM) doses of ENA-001.
- Trial name
- NCT06967259
- Testing
- ENA-001
- Where
- 2 sites in United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Enalare Therapeutics Inc.
LGBTQ, Racial Disparities
Family Acceptance Project Online (Pilot RCT)
Research shows that sexual and gender minority youth (SGMY) experience high rates of mental health problems and other challenges (e.g., social, academic).
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- FAP-O (NCT06839859)
- Testing
- Family Acceptance Project - Online
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Fermented Food, Depression
The Effect of Probiotic Foods on Depression
This exploratory study examined whether different frequencies of consuming three fermented foods commonly eaten in Türkiye-kefir, tarhana, and mixed pickles-were associated with short-term changes in body measurements and…
- Trial name
- NCT07846072
- Testing
- Individualized diet excluding fermented foods, Lower-frequency fermented-food dietary intervention, Higher-frequency fermented-food dietary intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nadide Gizem Tarakci Filiz
Mental Disorder, Depression
Screening to Identify Parents in Need of Mental Health Support: A Feasibility Study in Child Welfare Services
The main aim of this study is to evaluate the feasibility, preliminary effects and experiences of the Collaboration-Screening-Referral approach (CSR / in Swedish: Samverkan-Screening-Hänvisning - SSH) when used with parents…
- Conditions
- Mental Disorder, Depression, Anxiety, Child Abuse
- Trial name
- NCT06600139
- Testing
- The Collaboration-Screening-Referral (SSH) model
- Where
- Sweden
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Depressive Disorder, Major
Effects of Tryptophan Depletion on Brain Processing of Emotions in Patients With Mood Disorders
This study will investigate how the brain process emotions in healthy people and in patients who have major depression in order to better understand the causes of depression.
- Trial name
- NCT00097175
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
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