Clinical trials: Depression
Cognition, Affect (Mental Function)
PRECOG Pilot Project
This pilot study aims to investigate the chronic effects of a prebiotic blend on cognitive, affective and gut microbiome outcomes in healthy adults aged 60-75 years.
- Conditions
- Cognition, Affect (Mental Function), Gut Microbiome
- Trial name
- NCT06911957
- Testing
- Prebiotic blend
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Reading
Telerehabilitation, Chair-based Yoga
The Effects of Telerehabilitation And Chair-based Yoga In The Elderly
The aim of the study is to investigate the effects of chair-based yoga with rehabilitation on quality of life is affected in elderly people.
- Conditions
- Telerehabilitation, Chair-based Yoga, Elderly People
- Trial name
- NCT05598554
- Testing
- Telerehabilitation, information
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sevval Kadriye Bakir
Anxiety Disorder, Depression
Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes
This study evaluates the association between testosterone levels and risk of dementia and adverse mental health outcomes (e.g. depression and anxiety).
- Conditions
- Anxiety Disorder, Depression, Genetic Disorder, Hematopoietic and Lymphoid Cell Neoplasm
- Trial name
- NCT04743466
- Testing
- Electronic Health Record Review
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Anxiety Depression (Mild or Not Persistent)
Clinical Trials to Evaluate Neurophysiological and Neuropsychological Effects of a Mindfulness-based Intervention
Depression and anxiety are conditions with a high prevalence in the world population and youth are no exception. In developing countries it is reported that given the conditions of social disadvantage, anxiety and depression are…
- Trial name
- PRESENTE-IA (NCT06618339)
- Testing
- Mindfulness-based intervention
- Where
- Mexico
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Antenatal Depression, Major Depressive Disorder
Pilot Study of Personalized Aperiodic Transcranial Alternating Current Stimulation in Antenatal Depression (PandA-tACS)
The purpose of this study is to develop the safety, feasibility, and tolerability of a personalized transcranial alternating current stimulation (tACS) approach in antenatal depression.
- Conditions
- Antenatal Depression, Major Depressive Disorder, Major Depressive Disorder in Pregnancy, Healthy Controls
- Trial name
- PandA-tACS (NCT06979154)
- Testing
- tACS (aperiodic)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Major Depressive Disorder, MDD
Efficacy of Statins Among Major Depressive Disorder
The goal of this clinical trial is to learn if drug Rosuvastatin 10 mg works to treat MDD in adults. It will also learn about the safety of Rosuvastatin 10 mg .The main questions it aims to answer are: Does Rusovastatin lower the…
- Trial name
- NCT06698666
- Testing
- Rosuvastatin 10 mg tablet., Sertraline Pill
- Where
- Egypt
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anxiety, Depression
Metacognitive Bibliotherapy for Anxiety, Depression, and Metacognitions in University Students
This study tests whether reading a structured self-help book (bibliotherapy) can reduce anxiety, depression and stress and change unhelpful thinking patterns in medical and health-sciences students.
- Conditions
- Anxiety, Depression, Stress (Psychology)
- Trial name
- NCT07627139
- Testing
- Zihninde Çok Kuran İnsanlar için Salma Rehberi, Çapa Atmak
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
PostPartum Depression
The Effect of Exercise on Preventing PostPartum Depression
The purpose of this study is to examine the feasibility and efficacy of an exercise intervention for the prevention of postpartum depression.
- Trial name
- NCT00961402
- Testing
- Wellness Control, Exercise Intervention
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Postpartum Depression, Mood Disorders
Whole-Body Hyperthermia for Mood and Anxiety Disorders
This study aims to examine the scientific mechanisms of whole-body hyperthermia (WBH), a novel, rapidly acting, single session antidepressant and anxiolytic therapy.
- Conditions
- Postpartum Depression, Mood Disorders, Anxiety Disorders, Postpartum Anxiety
- Trial name
- NCT06144294
- Testing
- Whole-Body Hyperthermia, fMRI
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Lactation Suppressed, Cabergoline Adverse Reaction
Factors and Outcomes Associated With Postpartum Cabergoline Use
Cabergoline is frequently being requested by many postpartum women with a live newborn to suppress lactation. The aim of the study is to investigate which women desire such an intervention, and what side effects they are…
- Conditions
- Lactation Suppressed, Cabergoline Adverse Reaction, Postpartum DVT, Postpartum Depression
- Trial name
- NCT03965572
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Laniado Hospital
Mother-Infant Interaction
The Effect of Mother-Baby Yoga Baby Perception, Maternal Attachment,Depression-Anxiety-Stress
The research will be carried out in a randomized controlled manner to determine the positive benefits of yoga for mothers and babies who have given birth preterm and have been discharged, and to determine its effect on Fragile…
- Trial name
- NCT06202937
- Testing
- Mother Baby Yoga, No intervention:control
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Major Depressive Disorder
The Efficacy and Cerebral Mechanism of Intradermal Acupuncture for Major Depressive Disorder
Major depressive disorder (MDD) is highly prevalent, affecting nearly 4% of the global population. Pharmacotherapy is the frontline treatment recommended by the guideline, but it also has some limitations such as delayed onset…
- Trial name
- NCT05720637
- Testing
- SSRI, SIA, AIA
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Xiaomei Shao
Depression, Anxiety
The EARN-Health Trial of Financial Savings and Health
The current literature in social epidemiology and public health suggests that low financial savings has an unsurprising negative relationship with subjective well-being, and increases the odds of making visits to a healthcare…
- Conditions
- Depression, Anxiety, Alcohol Abuse, Tobacco Abuse
- Trial name
- EARN-Health (NCT02185612)
- Testing
- Savings program
- Where
- United States
- Volunteers
- 678 people, healthy volunteers welcome
- Sponsor
- Stanford University
Depression, Addiction
Adaptation and Pilot Testing of Web and Mobile Interface for the ATTACH™ Intervention
COVID-19 has placed unprecedented strains on parents impacted by toxic stressors (depression, addiction, family violence, and poverty) and reluctant to see mental health-service providers in home/clinic due to fears of infection.
- Conditions
- Depression, Addiction, Domestic Violence, Poverty
- Trial name
- ATTACH™ (NCT04857775)
- Testing
- Attachment and Child Health (ATTACH) Parenting Program
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Depression
Single Dose Study of BMS-820836
The purpose of this study is to determine the safety and tolerability of BMS-820836 after single doses
- Trial name
- NCT00964912
- Testing
- BMS-820836
- Where
- Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Depression
Assessing Anterior Cingulate Brain Activity in People With Late-Life Depression
This study will examine differences in activity of the anterior cingulate cortex, a brain area involved in emotion and cognitive regulation, between older adults with and without depression.
- Trial name
- NCT00926653
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Depression, Anxiety Disorders
Engaging Pacific Islanders in Mental Health Treatment
This study will create and pilot test a culturally grounded intervention (Talking Story) to increase mental health treatment seeking among Pacific Islanders with mental disorders (e.g., major depressive disorder, generalized…
- Trial name
- NCT04890977
- Testing
- Talking Story
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, Riverside
Rumination, Worry
Evaluating the Effects of a Self-help Mobile Phone Application on Worry and Overthinking in Young Adults Aged Between 16 and 24.
This project seeks to understand if a new self-help mobile phone application (called MyMoodCoach) is effective at reducing worry and overthinking, prominent risk factors that predict reduced well-being and poor mental health.
- Conditions
- Rumination, Worry, Repetitive Negative Thinking
- Trial name
- NCT04950257
- Testing
- digital CBT self-help including specific intervention elements to target worry and rumination.
- Where
- United Kingdom
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Fear of Childbirth, Stress
Effect of Antenatal Education on Fear of ChildBirth
The aim of this study was to investigate the effects of antenatal education on birth fear, depression, anxiety, stress, maternal self-efficacy, and mode of delivery in primiparous pregnant women
- Trial name
- NCT05584618
- Testing
- Education
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Major Depressive Disorder
Study of Safety, Tolerability and Pharmacokinetics of NRX-1074 in Normal Healthy Volunteers
The purpose of this study is to assess the safety and tolerability of multiple oral (PO) ascending doses of NRX-1074 in normal healthy volunteers.
- Trial name
- NRX-1074 (NCT02366364)
- Testing
- NRX-1074 375 mg, NRX-1074 500 mg, NRX-1074 750 mg
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Naurex, Inc, an affiliate of Allergan plc
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