Clinical trials: Depression Chronic
Depression
Open Label Trial of Fluoxetine for the Treatment of Depression in Patients With End Stage Renal Disease
The purpose of this study is to test whether once-weekly prozac therapy leads to reduction in depression in patients requiring kidney dialysis.
- Trial name
- NCT00573547
- Testing
- Fluoxetine
- Where
- 2 sites in United States
- Sponsor
- Creighton University
Depression
Organized Self-Management Support Services for Chronic Depression
The purpose is to test the effectiveness of an organized care program for chronic or recurrent depression. Using a two-arm design, the investigators will randomly assign 300 participants with chronic or recurrent depression to…
- Trial name
- Stride (NCT01139060)
- Testing
- organized care program for chronic or recurrent depression
- Where
- 2 sites in United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Chronic Pain, Depression
A Behavioral Intervention for Depression and Chronic Pain in Primary Care
Chronic pain and depression frequently co-exist in late and mid-life and contribute to increased disability, high health care costs, psychiatric comorbidity, and suicide.
- Trial name
- Relief (NCT03265210)
- Testing
- RELIEF
- Where
- 3 sites in United States
- Volunteers
- 73 people
- Sponsor
- Weill Medical College of Cornell University
Anxiety, Depression
VR Mindfulness Study
This is an exploratory study investigating the use of virtual reality-based guided mindfulness meditation in improving pain, stress, and mood within various clinical populations.
- Conditions
- Anxiety, Depression, Stress, Pain, Acute
- Trial name
- NCT05592782
- Testing
- Virtual Reality Based Mindfulness meditation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Refractory Depression, Anxiety Disorders
Near-Infrared Laser Stimulation for Various Neurological Conditions
The study will evaluate the safety and feasibility of near infrared therapy as an intervention for patients with refractory depression, anxiety, neurodegenerative disease, and traumatic brain injury.
- Conditions
- Refractory Depression, Anxiety Disorders, Neurodegenerative Diseases, Traumatic Brain Injury
- Trial name
- NCT04489082
- Testing
- Near Infrared Laser Stimulation
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Neurological Associates of West Los Angeles
Hypothyroidism Primary
Study of Chronic Fatigue, Depression, and Anxiety Among Hypothyroid Patients Attending Assuit University Hospitals
Assessment of the prevalence of chronic fatigue, depression, and anxiety among patients with hypothyroidism in Assuit University Hospital.
- Trial name
- NCT06660888
- Testing
- • Fatigue Severity Scale (FFS). • Hamilton Rating Scale for Depression (HRSD-17). • Hamilton Anxiety Rating Scale (HAM-A).
- Where
- Egypt
- Volunteers
- 406 people
- Sponsor
- Assiut University
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC
Bipolar Disorder, Depression
Disseminating Evidence-based Mood Disorder Chronic Care Models
This study will determine if a version of the chronic care model for individuals with mood disorders can improve patient health.
- Trial name
- NCT01615458
- Testing
- Chronic Care Model for Mood Disorders
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Depressive Symptoms, Anxiety
A Trial of a Positive Psychology Intervention for Older Adults (RESET)
The heightened vulnerability to COVID-19 of African American older adults in Detroit, Michigan and other marginalized communities is linked to systemic racism experienced over the life course.
- Conditions
- Depressive Symptoms, Anxiety, Chronic Pain, Fatigue
- Trial name
- NCT05451589
- Testing
- RESET, Wellness Check Control
- Where
- United States
- Volunteers
- 457 people
- Sponsor
- University of Michigan
Quality of Sleep, Subacute or Chronic Low Back Pain
Association Between Low Back Pain and Quality of Sleep
A prospective study to assess the association between the change in quality of sleep and the change in intensity of pain in Spanish patients seen for subacute or chronic low back pain.
- Conditions
- Quality of Sleep, Subacute or Chronic Low Back Pain, Disability, Catastrophizing
- Trial name
- NCT00906152
- Where
- 2 sites in Spain
- Volunteers
- 437 people
- Sponsor
- Kovacs Foundation
Depression, Headaches Chronic
CBT Depression Intervention for Co-Occurring Chronic Headache
Having co-occurring depression and chronic headaches is challenging and can greatly impact one's professional, personal, family, and social life.
- Conditions
- Depression, Headaches Chronic, Migraine Disorders
- Trial name
- NCT02870725
- Testing
- CBT Individual Psychotherapy
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- University of Georgia
Cerebral Palsy, Sleep Disorders in Children
Sleep Quality and Caregiver Burden in Children With Cerebral Palsy
Cerebral palsy (CP) is a lifelong condition affecting movement and posture, often requiring substantial care from family members.
- Conditions
- Cerebral Palsy, Sleep Disorders in Children, Caregiver Burden, Sleep Quality
- Trial name
- CP-SLEEP (NCT07168577)
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Selim Sezikli
COPD, Depression
Cognitive Behavioral Therapy for COPD
The purpose of this study in patients with advanced COPD and depression is twofold: 1. Determine the feasibility and acceptability of a 6-session e-counseling intervention 2.
- Trial name
- CLIMB (NCT01694628)
- Testing
- CLIMB (COPD Lifestyle, Mood, and Behavior)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Washington
Hypertension, Diabetes
mWELLCARE:An Integrated mHealth System for the Prevention and Care of Chronic Disease
Major barriers to controlling cardiovascular diseases (CVDs) in India and elsewhere are: low detection rates, inadequate use of evidence based interventions and low adherence with these interventions.
- Conditions
- Hypertension, Diabetes, Depression, Alcohol Use Disorder
- Trial name
- mWELLCARE (NCT02480062)
- Testing
- mWELLCARE, Usual Care
- Where
- 40 sites in India
- Volunteers
- 3,702 people
- Sponsor
- Public Health Foundation of India
Chronic Hepatitis C
Prevention of Depression With Omega-3 Fatty Acids in Chronic Carriers of Hepatitis C Treated With Interferon Alpha.
The purpose of the study is to check whether development of depression as a side effect of interferon alpha treatment in chronic carriers of hepatitis C can be prevented by omega-3 fatty acids.
- Trial name
- NCT00408304
- Testing
- omega-3 fatty acid
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Bnai Zion Medical Center
Anxiety, Cancer Survivor
Hypnotherapy in Treating Chronic Pain in Cancer Survivors
This randomized pilot clinical trial studies hypnotherapy in treating chronic pain in cancer survivors. Hypnotherapy is a state of concentration and focused attention which can provide more control over the experience of acute…
- Conditions
- Anxiety, Cancer Survivor, Chronic Pain, Depression
- Trial name
- NCT02637297
- Testing
- Hypnotherapy, Questionnaire Administration
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Fred Hutchinson Cancer Center
Respiratory Depression
Single Dose Crossover Study to Compare the Respiratory Drive After Administration of Belbuca, Oxycodone and Placebo.
The purpose of this study is to explore and compare VRH after administration of Belbuca, Oxycodone HCl and Placebo in recreational opioid users.
- Trial name
- NCT03996694
- Testing
- Belbuca 300 µg, Belbuca 600 µg, Belbuca 900 µg
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- BioDelivery Sciences International
Chronic Pain, Depression
Integrative Medicine Group Visits: A Patient-Centered Approach to Reducing Chronic Pain and Depression
The purpose of this study is to determine whether Integrative Medicine Group Visits (IMGV) are effective for treating patients with chronic pain and depression.
- Trial name
- IMGV (NCT02262377)
- Testing
- Integrative Medicine Group Visits
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Boston Medical Center
Coccydynia, Chronic Pain
Alexithymia, Pain Intensity, Quality of Life, and Psychological Symptoms in Chronic Coccydynia Patients Scheduled for Ganglion Impar Block
Chronic coccydynia is characterized by pain localized to the coccygeal region that typically worsens with sitting, leading to notable impairments in functional performance and health-related quality of life.
- Conditions
- Coccydynia, Chronic Pain, Alexithymia
- Trial name
- NCT07828145
- Testing
- Psychometric and Clinical Survey Battery
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Marmara University
COPD, Dyspnea
Dyspnea and Psychosocial Effects of Hand Fan Application in COPD Patients
This randomized controlled trial aims to evaluate the effects of hand fan application on dyspnea, illness perception, anxiety, and depression in COPD patients.
- Conditions
- COPD, Dyspnea, Illness Perception, Anxiety
- Trial name
- COPD (NCT06857422)
- Testing
- Hand Fan Application, Standard Care for COPD Patients
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Ardahan University