Clinical trials: Depression Chronic
Bipolar Disorder, Depression
Improving Mental Health Outcomes: Building an Adaptive Implementation Strategy
The overarching goal of this study is to build the most cost-effective adaptive implementation intervention involving a site-level implementation intervention strategy: Replicating Effective Programs (REP), and the augmentation…
- Conditions
- Bipolar Disorder, Depression, Mood Disorder
- Trial name
- NCT02151331
- Testing
- External Facilitation, External + Internal Facilitation
- Where
- 2 sites in United States
- Volunteers
- 383 people
- Sponsor
- University of Michigan
Chronic Pain, Depression
Equity Using Interventions for Pain and Depression - Pilot Study
This project is part of the NIH Helping to End Addiction Long-term (HEAL) initiative (https://heal.nih.gov/). This pilot randomized controlled trial (RCT) is part of phase 1 of a two-phase, 5-year project with the overarching…
- Conditions
- Chronic Pain, Depression, Health Equity
- Trial name
- EQUIPD-Pilot (NCT05695209)
- Testing
- Coaching and Decision Aid
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Indiana University
Insomnia Chronic
Aerobic Exercise Versus Digital Cognitive Behavioral Therapy for Insomnia
The purpose of this study is to compare the effects of aerobic exercise versus digital CBT-I in university students with insomnia complaints. This is a clinical trial.
- Trial name
- NCT06636006
- Testing
- Aerobic Exercise, Cognitive Behavioral Therapy for Insomnia
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Universidade Federal de Goias
Depression
Developing a Self-Management Program for People With Depression and Chronic Medical Illness
This study seeks to adapt an existing chronic disease self-management program for people with both chronic medical illness and depression.
- Trial name
- NCT00523029
- Testing
- Chronic Disease Self-Management Program
- Where
- 2 sites in United States
- Volunteers
- 104 people
- Sponsor
- University of Southern California
Depression
Cognitive Behavioral Therapy, Self-Efficacy, and Depression in Persons With Chronic Pain
The investigators are exploring the role of Cognitive Behavioral Therapy (CBT), a treatment for depression, on self-efficacy (feeling empowered to accomplish a given task) and depression in persons with chronic pain and…
- Trial name
- NCT01055665
- Testing
- cognitive behavior therapy
- Volunteers
- 138 people
- Sponsor
- Mayo Clinic
Chronic Disease
Effect of Music Therapy on Hospital Anxiety/Depression and Comfort Level
Aim: It has been determined that there are limited studies in our country where music is used as a nursing intervention and the effects of music therapy on the psychological symptoms and comfort levels of individuals with chronic…
- Trial name
- NCT06865729
- Testing
- Music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Amasya University
Chronic Pain, Depression
Clinical Efficacy and Immune Effects of Acupuncture in Patients With Comorbid Chronic Pain and Major Depression Disorder
Background: Depression and pain are highly comorbid and share biological mechanisms. Acupuncture is commonly used to manage both pain and depression, but the choice of acupoints for specific disorders differs.
- Trial name
- NCT03328819
- Testing
- Acupuncture
- Where
- Taiwan
- Volunteers
- 75 people
- Sponsor
- China Medical University Hospital
Major Depression
Cognitive Behavioral Treatments for Depression in Chronic Illness
Duke University Medical Center in collaboration with Glendale Adventist Medical Center propose a randomized clinical trial of conventional cognitive behavior therapy (CCBT) vs.
- Trial name
- NCT01208428
- Testing
- Conventional cognitive behavioral therapy, Religious cognitive behavioral therapy
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- Duke University
Tinnitus, Depression
Home-based Transcranial Electrical Stimulation (TES) in Patients With Chronic Tinnitus
The investigators applied home-based transcranial electrical stimulation (TES) for neuromodulative treatment in patients with intractable chronic tinnitus.
- Conditions
- Tinnitus, Depression, Depressive Disorder, Hearing Disorders
- Trial name
- NCT05189587
- Testing
- transcranial electrical stimulation (TES)
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Depression, Post-COVID-19 Syndrome
Evaluation of DEPREXIL in Patients With Clinical Depression Through Psychological and Neuroendocrine Assessment
Clinical depression is a mood disorder that affects people of all ages with symptoms such as sadness, anger or frustration, appetite changes, difficulty concentrating and suicidal thoughts.
- Conditions
- Depression, Post-COVID-19 Syndrome, Depression Mild, Depression Moderate
- Trial name
- NCT06496087
- Testing
- DEPREXIL
- Where
- Colombia
- Volunteers
- 100 people
- Sponsor
- Catalysis SL
Caregivers, Dementia
Powerful Tools for Caregivers of Dementia Patients
The purpose of this study is to examine if a psycho-educational intervention for caregivers of patients with dementia will decrease caregiver burden, increase caregiver physical activity, and decrease the reporting of behavioral…
- Conditions
- Caregivers, Dementia, Alzheimer Disease
- Trial name
- PTC-dementia (NCT02697721)
- Testing
- Powerful Tools for Caregivers, Control with delayed intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Florida State University
Exercise Therapy, Chronical Kidney Disease
Therapeutic Exercise Programme to Improve the Functional Capacities, Depression and Anxiety of Patients With Chronic Kidney Disease During Haemodialysis Sessions.
Therapeutic Exercise During Outpatient Hemodialysis Treatment for Patients with Chronic Kidney Disease
- Trial name
- Actyren-HD (NCT06883968)
- Testing
- Therapeutic exercise during hemodialysis session
- Where
- Spain
- Volunteers
- 67 people
- Sponsor
- University of Vic - Central University of Catalonia
Chronic Kidney Diseases, Major Depressive Disorder
Combination of Novel Therapies for CKD Comorbid Depression
The overall goal of the study is to determine if treatment of a Major Depressive Disorder (MDD) improves the outcomes of patients with chronic kidney disease (CKD).
- Conditions
- Chronic Kidney Diseases, Major Depressive Disorder, End Stage Kidney Disease (ESRD)
- Trial name
- CONCORD (NCT04422652)
- Testing
- Bupropion, Behavioral activation therapy, Clinical Management
- Where
- 4 sites in United States
- Volunteers
- 201 people
- Sponsor
- Stony Brook University
Hematoma, Subdural, Chronic, Hematoma, Subdural, Intracranial
Covers to Improve Esthetic Outcome After Surgery for Chronic Subdural Hematoma
The clinical-functional result after frontal and parietal burr-hole trepanation for the treatment of chronic subdural hematoma (cSDH) is effective with regards to control of the hematoma and regression of symptoms (headache…
- Conditions
- Hematoma, Subdural, Chronic, Hematoma, Subdural, Intracranial, Haematoma;Subdural;Traumatic
- Trial name
- CORRECT-SCAR (NCT03755349)
- Testing
- Placement of burr-hole covers, No placement of burr-hole covers
- Where
- Switzerland
- Volunteers
- 83 people
- Sponsor
- University of Zurich
Treatment Resistant Depression, Suicidal Ideation
The Safety and Efficacy of Psilocybin in Patients With Treatment-resistant Depression and Chronic Suicidal Ideation
This study aims to explore the safety and tolerability of a single dose of psilocybin (25mg) administered under supportive conditions to adult participants with TRD and chronic suicidal ideation
- Trial name
- NCT05220410
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sheppard Pratt Health System
Traumatic Brain Injury (TBI)
Allopregnanolone in Chronic Complex Traumatic Brain Injury
This study will determine if allopregnanolone (ALLO) improves depression and pain symptoms in patients who have a history of mild traumatic brain injury (TBI) [primary endpoints].
- Trial name
- ALLO (NCT04003285)
- Testing
- Allopregnanolone
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- VA Office of Research and Development
Insomnia, Insomnia Chronic
Assessment of Sleep Quality and Mental Health After Using Meditation
This is a randomized controlled trial that intends to verify the effectiveness of the daily practice of meditation before going to sleep for the improvement of sleep, stress, mental health and quality of life of people with sleep…
- Conditions
- Insomnia, Insomnia Chronic, Insomnia Disorder, Sleep Disorder
- Trial name
- NCT05812443
- Testing
- Shabad Kriya Meditation, Relaxing reading
- Where
- Brazil
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Chronic Obstructive Pulmonary Disease
Effect of Home Exercise Activity on Cortisol and Depression in COPD During the Pandemic COVID
exercise activity during the COVID pandemic is appreciated to be conducted in home especially for chronic chest diseases as chronic obstructive pulmonary disease (COPD) to reduce the chance of viral contamination during the…
- Trial name
- NCT04639349
- Testing
- exercise group, control group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Chronic Disease, Depression
Improving Mental Health Through Integration With Primary Care in Rural Karnataka
This cluster Randomized Controlled Trial was designed to implement and evaluate the effects of a multi-level intervention designed to integrate mental health treatment into rural primary health clinics in South India using a…
- Conditions
- Chronic Disease, Depression, Anxiety
- Trial name
- NCT02310932
- Testing
- Healthy Living Intervention
- Where
- India
- Volunteers
- 2,507 people
- Sponsor
- University of California, San Francisco
Medical Complication
Postoperative Opioid and Respiratory Depression in Opioid Naive and Chronic Opioid Patients
Aim: To describe the duration of desaturation and bradypnea in postoperative opioid-naïve and chronic opioid patients. Patients: 691 patients included from two previous WARD (Wireless Assessment of Respiratory and circulatory…
- Trial name
- NCT06227208
- Testing
- Continuous vital sign monitoring
- Where
- 2 sites in Denmark
- Volunteers
- 691 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet