Clinical trials: Depression Chronic, open to volunteers
Chronic Pain, Musculoskeletal Pain
Equipping Patients Using Interventions for Pain and Depression
This project is part of the NIH Helping to End Addiction Long-term (HEAL) initiative (https://heal.nih.gov/). This randomized controlled trial (RCT) is phase 2 of a two-phase, 5-year project with the overarching goal of testing a…
- Conditions
- Chronic Pain, Musculoskeletal Pain, Depression, Health Equity
- Trial name
- EQUIPD (NCT06500780)
- Testing
- Coaching and Decision Aid
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- Indiana University
Chronic Atrophic Gastritis, Depressive Symptoms
Objective Vascular Biomarkers as Triage for Depression in Chronic Atrophic Gastritis
Depressive symptoms are highly prevalent in patients with chronic atrophic gastritis (CAG) but are frequently under-detected due to stigma and reliance on subjective questionnaires.
- Conditions
- Chronic Atrophic Gastritis, Depressive Symptoms, Depression, Gastrointestinal Diseases
- Trial name
- NCT07319338
- Testing
- Vascular-Psychological Triage Workflow
- Where
- 4 sites in China
- Volunteers
- 520 people
- Sponsor
- China Academy of Chinese Medical Sciences
End-stage Chronic Kidney Disease Treated With Hemodialysis, Depressive Disorders
Evaluation of the Effect of Light Therapy on the Evolution of Self-reported Depressive Disorders in Chronic Hemodialysis Patients
Hemodialysis is an intensive treatment, with a lifestyle dictated by the organization of the dialysis center. This treatment is associated with a decrease in quality of life, an increase in sleep disorders, and depressive…
- Trial name
- LUMIDIAL-2 (NCT07729358)
- Testing
- Light therapy using active glasses, Light therapy using inactive glasses
- Where
- France
- Volunteers
- 340 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Mild Cognitive Impairment (MCI), Dementia Alzheimer Type
Global Collaborative Research on Establishing a Korean Cognitive Aging Cohort
The goal of this observational study is to learn how daily emotional stress affects cognitive function and inflammation in community-dwelling older adults aged 60 and older in Seoul, Republic of Korea.
- Conditions
- Mild Cognitive Impairment (MCI), Dementia Alzheimer Type, Chronic Pain, Depression - Major Depressive Disorder
- Trial name
- KoCoA cohort (NCT07485387)
- Where
- South Korea
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Korea University
Chronic Obstructive Pulmonary Disease, Depression
Effectiveness and Cost-effectiveness of Digital Psychological Intervention (EmoEase) in Chinese COPD Patients
Background Mental health issues are common and often overlooked in COPD patients. Digital psychological interventions might help, but their effectiveness in Chinese COPD patients hasn't been studied.
- Conditions
- Chronic Obstructive Pulmonary Disease, Depression, Anxiety
- Trial name
- NCT06026709
- Testing
- EmoEase
- Volunteers
- 1,200 people
- Sponsor
- Peking Union Medical College
Treatment Resistant Depression (TRD), Chronic Pain
Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression
The goal of this clinical trial is to understand the effect of ketamine on the brain in people with treatment-resistant depression (TRD).
- Trial name
- NCT07247006
- Testing
- Ketamine hydrochloride injection
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Rochester
COPD, Nursing Care
The Effect of Bedside Whiteboard Use on Anxiety, Depression and Nursing Care in Chronic Obstructive Pulmonary Patients
ABSTRACT Chronic obstructive pulmonary disease (COPD) is a disease characterized by the inability of the body to adequately exchange gases, resulting in progressive shortness of breath that can form secretions and compromise the…
- Trial name
- NCT06929221
- Testing
- use of whiteboard
- Volunteers
- 128 people
- Sponsor
- Agri Ibrahim Cecen University
Long COVID, Long COVID Syndrome
Evaluation of MicroRNAs and Vitamin B12 Expression in Subjects with Neurologic Symptoms of Depression, Anxiety and Fatigue in Long COVID-19
At the moment, the number of people with long COVID is unkown because there is still no effective diagnosis. This is why is very important to analyze the most common symptoms, which are: depression, anxiety and fatigue.
- Trial name
- NCT06864156
- Where
- Mexico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Rehabilitacion
Neck Pain, Quality of Life
Chronic Non-Specific Neck Pain and Quality of Life
The factors affecting the quality of life in individuals with chronic non-specific neck pain are not fully known in the studies conducted to date.
- Trial name
- NCT06777862
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Depression, Cost Benefit Analysis
Dysthymia: Associated Costs, Treatment and Change Process
The study evaluates cost and effect of inpatient versus outpatient treatment of dysthymia, as well as investigates the processes through which psychotherapy works in treating dysthymia.
- Conditions
- Depression, Cost Benefit Analysis, Psychotherapeutic Processes
- Trial name
- DFront (NCT04911829)
- Testing
- Psychotherapy
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Modum Bad
Cognitive Dysfunction, Stroke
Vascular mEchanisms in, Stroke, dePression, dementiA, and deliRum: The VESPAR Project
The goal of this observational study is to determine the feasibility of using integrated Transcranial Doppler Ultrasonography or Near Infrared Spectroscopy to detect changes in cerebral autoregulation and neurovascular coupling…
- Conditions
- Cognitive Dysfunction, Stroke, Dementia, Depression
- Trial name
- VESPAR (NCT05649800)
- Where
- 2 sites in United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Cognition, Affect (Mental Function)
ETASCAN Project: ETAS Project 2
This study aims to investigate the chronic effects of ETAS® on cognitive, affective and neural outcomes in healthy adults aged 60-80 years with mild to moderate subjective cognitive complaints.
- Conditions
- Cognition, Affect (Mental Function), Sleep, MRI
- Trial name
- ETASCAN (NCT07550140)
- Testing
- ETAS®
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Reading
Burn, Chronic Pain Following Thermal Burn Injury
VR-PMR for Post-Burn Symptoms
The goal of this clinical trial is to learn whether progressive muscle relaxation (PMR), delivered either alone or enhanced with virtual reality (VR), can help treat chronic symptom, such as pain, itch, anxiety, sleep…
- Conditions
- Burn, Chronic Pain Following Thermal Burn Injury, Non-Pharmacological Interventions, Virtual Reality
- Trial name
- VIBE (NCT07317271)
- Testing
- Virtual Reality-Enhanced Progressive Muscle Relaxation, Standard Progressive Muscle Relaxation
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Johns Hopkins University
Major Depressive Disorder
Pharmacologic Treatment Augmentation in Chronic Depression
To enroll in this clinical trial, prospective participants must meet stringent criteria. The participants need to fall within the age range of 18 to 64 and exhibit chronic depression at therapy resistance stage 2.
- Trial name
- Ket+CBASP (NCT06410599)
- Testing
- Ketamine, CBASP, TAU
- Where
- 2 sites in Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Tuebingen
Depression Chronic, Depressed
Evaluation of Dalia Solution For Depressed Patient
The goal of this superiority clinical investigation, prospective, multicenter, controlled, randomized, open-label is to evaluate the clinical impact of the Dalia medical telemonitoring device on the management of depressive…
- Conditions
- Depression Chronic, Depressed, Depressed Mood, Depression and Quality of Life
- Trial name
- DaliaMonitorin (NCT07211984)
- Testing
- Dalia Monitoring, Conventional healthcare
- Where
- France
- Volunteers
- 644 people
- Sponsor
- Dalia Care
Chronic Pain, Depressive Disorder
Ketamine Treatment Plans for Chronic Conditions
A study aimed to assess the efficacy of the various approaches to prescribing Ketamine currently in use off-label. The focus will be to include ketamine within the study plan of those with chronic conditions who are receiving…
- Conditions
- Chronic Pain, Depressive Disorder, Anxiety Disorders, Chronic Disease
- Trial name
- NCT06038409
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- RIVER Foundation
Chronic Pain, Depression
Mindfulness-based Cognitive Therapy vs the Health Enhancement Program for Chronic Pain and Depression; The Quiet Focus Study
The goal of this clinical trial is to pilot a randomized controlled trial comparing an adaptation of mindfulness-based cognitive therapy to the health enhancement program for chronic pain and depression.
- Trial name
- NCT07118722
- Testing
- Quiet Focus, Health Enhancement Program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Chronic Tinnitus, Anxiety
Internet-Based Mindfulness-Based Cognitive Therapy (iMBCT) for Chronic Tinnitus Patients
This study tested a 6-week, internet-based Mindfulness-Based Cognitive Therapy (MBCT) program designed to help people experiencing distress related to chronic tinnitus.
- Conditions
- Chronic Tinnitus, Anxiety, Depressive
- Trial name
- NCT07183826
- Testing
- Mindfulness-Based Cognitive Therapy (Internet-delivered), No intervention
- Where
- Poland
- Volunteers
- 78 people
- Sponsor
- University of Warsaw
Chronic Pain, Acute Pain
Evaluating the Impact of Focused Muscle Contraction Therapy in U.S. Veterans
This research study is being done to investigate if the GH Method exercise program positively affects body composition, improves physical abilities and can improve the overall sense of wellbeing (e.g.
- Conditions
- Chronic Pain, Acute Pain, Fatigue, Depression
- Trial name
- NCT05094297
- Testing
- Investigate the effects of an exercise intervention on U.S. Veterans.
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Illinois Chicago
Benzodiazepine Adverse Reaction, Depression, Anxiety
Benzodiazepine Impact on Cognitive Function: fNIRs and PET/MRI Study
This study explores the impact of long-term benzodiazepine (BZDs) use on cognitive function and associated neuroimaging markers.
- Conditions
- Benzodiazepine Adverse Reaction, Depression, Anxiety, Benzodiazepine Dependence
- Trial name
- NCT06250842
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Dalian Medical University