Clinical trials: Depression Diagnosis
Psoriatic Arthritis, Depression
Evaluating the Role of IL-17 as an Orchestrator of Peripheral-central Cross Talk in Depressive Symptoms
The investigators seek clinically actionable understanding of the mechanisms that underlie depression in the context of immune mediated inflammatory diseases (IMIDs), delivered by a focused immune intervention study examining…
- Conditions
- Psoriatic Arthritis, Depression, Psoriatic Plaque
- Trial name
- ELATE (NCT06786936)
- Testing
- Secukinumab, Bimekizumab, Ixekizumab
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- NHS Greater Glasgow and Clyde
Suicide, Mental Health Disorder
A Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents
Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death amongst youth. Digital tools, especially personal smartphones, are promising avenues to address these issues and can be…
- Conditions
- Suicide, Mental Health Disorder, Anhedonia
- Trial name
- ViraSafeRCT (NCT07348666)
- Testing
- ViraSafe: Treatment pushes, BRITE
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Ksana Health
Stress Disorders, Post-Traumatic, Depression
Veteran Health Study
The purpose of The Veteran Health Study (CSP #569) is to better understand the mental and physical health of veterans as they get older.
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Diabetes, Cardiovascular Disease
- Trial name
- NCT01175629
- Where
- United States
- Volunteers
- 7,568 people
- Sponsor
- US Department of Veterans Affairs
Major Depressive Disorder
D-cycloserine for Major Depressive Disorder
For many depression patients treatment changes are required, including switching to another antidepressant and addition of a second antidepressant or a non-antidepressant agent ("augmentation").
- Trial name
- NCT00408031
- Testing
- D-cycloserine
- Where
- 2 sites in Israel
- Volunteers
- 26 people
- Sponsor
- Herzog Hospital
Elderly, Muscle Loss
Effect of Lactobacillus Paracasei PS23 on Improving Aging and Muscle Loss in the Elderly
This study refers to the supplementation of PS23 in human experiments to help the elderly maintain muscle mass, delay muscle loss, promote physical activity, and delay the occurrence of disability and debilitation in elderly…
- Conditions
- Elderly, Muscle Loss, Depression, Anxiety
- Trial name
- NCT06062472
- Testing
- Probiotics, heat-treated of Lactobacillus paracasei HT-PS23
- Where
- Taiwan
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Chi-Chang Huang
Cerebral Palsy, Sleep Disorders in Children
Sleep Quality and Caregiver Burden in Children With Cerebral Palsy
Cerebral palsy (CP) is a lifelong condition affecting movement and posture, often requiring substantial care from family members.
- Conditions
- Cerebral Palsy, Sleep Disorders in Children, Caregiver Burden, Sleep Quality
- Trial name
- CP-SLEEP (NCT07168577)
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Selim Sezikli
Depression, Major Depressive Disorder
The Effects of Wellbutrin (Bupropion) on Residual and Cognitive Symptoms in SSRI-treated Depression
Many people with depression are treated with a serotonin-specific reuptake inhibitor anti-depressant (SSRI) and feel 'better'. Although many people feel 'better', they do not feel completely 'well'.
- Conditions
- Depression, Major Depressive Disorder, Unipolar Depression
- Trial name
- NCT00125957
- Testing
- Wellbutrin
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Mclean Hospital
Posttraumatic Stress Disorder, Depression
A Randomized Controlled Clinical Trial With Orphans and Widows Who Experienced the Rwandan Genocide
In the framework of the epidemiological study, local psychologists are trained in Butare in carrying out diagnostic interviews with orphans and widows who experienced the Rwandan genocide.
- Conditions
- Posttraumatic Stress Disorder, Depression, Prolonged Grief Disorder
- Trial name
- NCT00553956
- Testing
- Narrative Exposure Therapy/Interpersonal Psychotherapy
- Where
- Rwanda
- Volunteers
- 150 people
- Sponsor
- University of Konstanz
Mental Health, Psychological Trauma
Pathway-Matched Resilience-Oriented Therapy in Rwanda
This pragmatic, pathway-stratified, cluster-randomized waitlist-controlled trial evaluated Resilience-Oriented Therapy (RoT), a culturally adapted group-based psychosocial intervention for post-genocide Rwanda.
- Conditions
- Mental Health, Psychological Trauma, Stress Disorders, Post-Traumatic, Depression
- Trial name
- RoT-CRT (NCT07621731)
- Testing
- Resilience-Oriented Therapy - Emotion-Regulation Variant, Resilience-Oriented Therapy - Identity-Development Variant, Resilience-Oriented Therapy - Behavioural Self-Management Variant
- Where
- 5 sites in Rwanda
- Volunteers
- 427 people
- Sponsor
- Alexandros Lordos, PhD
Tobacco Use Cessation, Tobacco Use Disorder
Effectiveness of Bupropion for Treating Nicotine Dependence in Young People
Little is known about the best ways to help young people stop smoking. Bupropion (a medication marketed as Wellbutrin or Zyban) has proved helpful in treating adult smokers.
- Trial name
- NCT00129272
- Testing
- Bupropion-SR
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Major Depressive Disorder
Intradermal Acupuncture as an Adjunct to SSRI Tapering in Major Depressive Disorder
This randomized controlled trial aims to evaluate the clinical efficacy of intradermal acupuncture as an adjunctive intervention to assist selective serotonin reuptake inhibitor (SSRI) dose reduction or discontinuation in adult…
- Trial name
- NCT07390981
- Testing
- Selective Serotonin Reuptake Inhibitors (SSRIs), Intradermal Acupuncture
- Volunteers
- 114 people
- Sponsor
- First People's Hospital of Hangzhou
Depression
Managing Cancer and Living Meaningfully (CALM) Therapy in Individuals Diagnosed With a Primary Brain Tumor
Background: Psychological distress affects many people diagnosed with a primary central nervous system tumor (CNST). Distress can include negative feelings such as anger, fear, or sadness.
- Trial name
- NCT04852302
- Testing
- Cancer and Living Meaningfully (CALM) Therapy
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- National Cancer Institute (NCI)
Major Depressive Disorder
Pharmacogenomic Testing in Major Depressive Disorder
This is a two-arm double-blind prospective randomized controlled trial (RCT) to evaluate clinical impact of pharmacogenomic testing on the treatment of major depressive disorder.
- Trial name
- NCT03228953
- Testing
- Pharmacogenomic testing
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Columbia University
Aging, Addiction
Based-virtual Reality Diagnosis for Neuropsychiatric Diseases and Sleep/Wake Disorders
The objective of this research is to develop original virtual reality scenarios and/or new virtual reality equipments to evaluate or diagnose pathologies, such as attention deficit disorders or neuropsychiatric pathologies…
- Conditions
- Aging, Addiction, Attention Deficit Disorder With Hyperactivity, Sleep Disorders
- Trial name
- PHENOVIRTPSY (NCT02544295)
- Testing
- Clinical interview, Virtual reality task
- Where
- France
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- University of Bordeaux
Dementia, Caregivers
VA Cultivating Access to Resources, Education, and Skills for Dementia Caregivers
The purpose of this study is to study the effects of an education and skill-building intervention on family caregivers of Veterans with dementia.
- Conditions
- Dementia, Caregivers, Neurodegenerative Diseases, Brain Diseases
- Trial name
- VACARES (NCT02106065)
- Testing
- Education and Skill-Building Rehabilitation (ESBR), Supplemental Education Materials
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Major Depressive Disorder, Depression
A Study to Assess the Efficacy and Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder
The purpose of this study is to determine if TC-5214 or placebo (a tablet that looks like medicine tablet or capsule, but contains no active medicine) is safe and effective when taken together with another antidepressant.
- Trial name
- NCT01180400
- Testing
- TC-5214
- Where
- 66 sites in Czechia, Estonia and 8 more
- Volunteers
- 295 people
- Sponsor
- AstraZeneca
Postpartum Depression
A Study To Assess The Safe-Use Conditions For Administration of ZULRESSO® in a Home Setting
The primary purpose of this study was to evaluate whether the safe-use conditions for administration of brexanolone (ZULRESSO®) can be implemented in a home setting.
- Trial name
- NCT05059600
- Testing
- ZULRESSO®
- Where
- 6 sites in United States
- Volunteers
- 52 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
Psychosis, Substance Abuse
Effect Evaluation of Individual Placement and Support (IPS)
Roughly one third of disability pensions issued in Norway are classified as mental and behavioral disorders. The proposed study aims to evaluate the effect of an innovative intervention for returning people with moderate to…
- Conditions
- Psychosis, Substance Abuse, Depression, Anxiety
- Trial name
- NCT01964092
- Testing
- Individual Placement and Support, Ordinary employment schemes
- Where
- Norway
- Volunteers
- 410 people
- Sponsor
- NORCE Norwegian Research Centre AS
Musculoskeletal Disorder, Anxiety Disorders
A Multicentre Randomised Controlled Trial of the Norwegian Health in Work Service. The NSAC Efficacy Study
The Norwegian Sickness Absence Clinic (NSAC) is a publicly funded specialist outpatient health service, which is uniquely available for the work force.
- Conditions
- Musculoskeletal Disorder, Anxiety Disorders, Depression, Fatigue
- Trial name
- NSAC (NCT05310695)
- Testing
- NSAC - rapid, NSAC - ordinary, NSAC - active control
- Where
- 5 sites in Norway
- Volunteers
- 2,500 people
- Sponsor
- Nordlandssykehuset HF
Anxiety, Depression
Blending Two Worlds: Traditional Aboriginal Healing Strategies for Depression and Anxiety
1. Purpose 1. Provide a culturally sensitive and supportive treatment environment for children, youth and families in the aboriginal community experiencing stress, anxiety and depression. 2.
- Trial name
- B2W (NCT00749177)
- Testing
- Traditional Healing options
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- Fraser Health
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