Clinical trials: Depression Diagnosis
Depression
Sequenced Treatment Alternatives to Relieve Depression (STAR*D)
STAR*D focuses on non-psychotic major depressive disorder in adults who are seen in outpatient settings. The primary purpose of this research study is to determine which treatments work best if the first treatment with medication…
- Trial name
- NCT00021528
- Testing
- citalopram, BuproprionSR, buspirone
- Where
- 41 sites in United States
- Volunteers
- 4,000 people
- Sponsor
- National Institute of Mental Health (NIMH)
Anxiety Disorders, Depression
Electronic Media and Its Application in Psychotherapy
This randomized control trial aims to establish whether viewing and discussing patients' electronic communication (texts, emails, Facebook direct messaging, etc) impacts clinical care and decision making across the lifespan.
- Conditions
- Anxiety Disorders, Depression, Electronic Media
- Trial name
- NCT03712267
- Testing
- Electronic Media Enhanced, Treatment as Usual
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Mclean Hospital
Metabolic Syndrome
Determination Physical Activity Levels,Quality Life,Depression and Fatigue Severity Individuals With Metabolic Syndrome
The aim of the study was to determine the Physical Activity Levels, Quality of Life, Depression and Fatigue Severity of Individuals with Metabolic Syndrome.
- Trial name
- NCT05184634
- Testing
- PHYSICAL ACTIVITY LEVELS, DEPRESSION LEVELS, FATİGUE SEVERİTY
- Where
- Turkey (Türkiye)
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Büşra Sarıkaya
Depression, Anxiety
Sedentary Behavior and Depressive Symptoms
Depressive symptoms are commonly observed in the general population. Individuals with subclinical forms of depression (e.g., not meet the criteria to major depression disorder) are at increased risk of mortality than the general…
- Trial name
- NCT07007234
- Testing
- Physical activity intervention, Standard of care
- Where
- 2 sites in Brazil
- Volunteers
- 84 people
- Sponsor
- University of Sao Paulo General Hospital
Depression
Electrical Stimulation in Patients With Unipolar Major Depression
Double Blinded Randomized Trial of sTNS as adjuvant treatment for Major Unipolar Depressive Disorder. The primary objective is to assess the safety and tolerability of an implantable sTNS of the V1 branch of the trigeminal nerve…
- Trial name
- TREND1 (NCT02239809)
- Testing
- Stimulation of the trigeminal nerve (active stimulation)
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital do Coracao
Well-being, Stress
The Impact of Mindfulness and Spirituality on Student Well-being
The purpose of this research is to find effective ways of well-being promotion in higher education settings. A unique mindfulness training was developed that includes cognitive, emotional, social, and spiritual components.
- Conditions
- Well-being, Stress, Anxiety, Depression
- Trial name
- MSW (NCT05397249)
- Testing
- Mindfulness Training
- Where
- 2 sites in United States
- Volunteers
- 514 people, healthy volunteers welcome
- Sponsor
- University of Houston
Major Depressive Disorder
A Randomised Double-Blind Trial of Targeted Repetitive Transcranial Magnetic Stimulation in Major Depressive Disorder
The study will involve a 3-week (15 session) randomized double-blind clinical trial of two repetitive transcranial magnetic stimulation (rTMS) conditions in patients with treatment resistant depression.
- Trial name
- NCT00168376
- Testing
- Transcranial Magnetic Stimulation
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- The Alfred
Premature Birth, Theory, Double Bind
The Meleis Theory on Postpartum Depression, Breastfeeding, and Maternal Self-Efficacy in Women Experiencing Preterm Birth
The aim of this study was to evaluate the effect of a nursing approach based on Meleis' Transition Theory on postpartum depression, maternal self-efficacy and breastfeeding self-efficacy in women who gave birth preterm.
- Conditions
- Premature Birth, Theory, Double Bind, Postpartum Depression, Breast Feeding
- Trial name
- NCT06250933
- Testing
- Postpartum Maternal Care and Premature Infant Care Training
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bilecik Seyh Edebali Universitesi
Postoperative Complications, Respiratory Depression
Comparison of Remimazolam and Propofol in Endoscopic Examinations and Treatments
This study aims to evaluate the efficacy and safety of Remimazolam, either used alone or in combination with Propofol, for moderate sedation anesthesia during endoscopic therapies or examinations.
- Conditions
- Postoperative Complications, Respiratory Depression, Postoperative Nausea, Vomiting
- Trial name
- Remimazolam (NCT06777758)
- Testing
- Remimazolam, Propofol
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Depression
The Early Medication Change (EMC) Trial
The EMC trial investigates for the first time prospectively whether Major Depression Disorder patients with non-improvement after 14 days of antidepressive treatment with EMC are more likely to become remitters compared to…
- Trial name
- EMC (NCT00974155)
- Testing
- Escitalopram, venlafaxine, lithium, Escitalopram, venlafaxine
- Where
- Germany
- Volunteers
- 889 people
- Sponsor
- K. Lieb
Substance Use Disorders (SUD)
Substance-focused SBI as a Complement to Internet-based Psychiatric Treatment: RCT
Objectives: This study evaluates the efficacy of eScreen for internet psychiatry patients treated for major depressive disorder, panic anxiety and social phobia.
- Trial name
- eScreeniPsy (NCT01885026)
- Testing
- eScreen, Assessment only of alcohol and drug use., Internet-based treatment for depression or anxiety
- Where
- Sweden
- Volunteers
- 93 people
- Sponsor
- Karolinska Institutet
Therapy-resistant Depression
Aripiprazole Augmentation Therapy in Treatment-resistant Depression
20 therapy-refractory patients with major depression will be treated for 3 weeks with Aripiprazole 10 mg/d. Effectivity will be assessed using a pre-post comparison of different psychopathological rating scales and patient…
- Trial name
- NCT00276978
- Testing
- Aripiprazole
- Where
- Germany
- Sponsor
- University Hospital Freiburg
Unipolar Depression, Anxiety Disorder
Improve: Integrating Emotion Focused Components Into Psychological Therapy
The primary purpose of this study is to compare the efficacy of two treatment-as-usual (TAU) conditions: TAU with integration of emotion focused components (EFT) and TAU with focus on self-regulation (SR).
- Conditions
- Unipolar Depression, Anxiety Disorder, Adjustment Disorder
- Trial name
- Improve (NCT02822443)
- Testing
- Psychological therapy (PT) as TAU with integrated emotion focused components (TAU - EFT), Psychological therapy (PT) as TAU with focus on self-regulation (TAU - SR)
- Where
- Switzerland
- Volunteers
- 104 people
- Sponsor
- University of Bern
Emotional Disorder, Anxiety
Unified Protocol for Bariatric Surgery Candidates
The present pilot study with a multiple baseline experimental desing will verify the feasibility and clinical utility of the Unified Protocol, applied in an online group format in a mental health setting of the Spanish national…
- Conditions
- Emotional Disorder, Anxiety, Depression
- Trial name
- NCT04421443
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Jorge Javier Osma López
Stress, Psychological, Stress Disorders, Traumatic
Intergenerational Transmission of Traumatic Stress
Millions of U.S. parents have experienced trauma, putting them at risk for maladaptive parenting practices, which then confer vulnerabilities to their children.
- Conditions
- Stress, Psychological, Stress Disorders, Traumatic, Emotion Regulation, Behavior, Child
- Trial name
- NCT05264415
- Testing
- Families OverComing Under Stress (FOCUS) for Early Childhood (FOCUS-EC), Parenting Education Website
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, Los Angeles
Mental Health
Educational Intervention for Optimizing Adolescent Mental Health Screening and Treatment in Pediatric Residency
The purpose of this study is: 1) to assess pediatric resident knowledge of adolescent mental health; 2) to assess pediatric resident comfort level for screening, assessing, and treating mental health disorders in adolescents…
- Trial name
- NCT00768352
- Testing
- Educational intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Postnatal Depression
Effect of a Telephone-based Intervention on Postnatal Depression
Purpose: To evaluate the effectiveness of a telephone-based intervention using cognitive-behavioral approach in preventing postnatal depression and improving quality of life in first-time Chinese mothers.
- Trial name
- NCT01507649
- Testing
- telephone-based cognitive-behavioral intervention
- Where
- Hong Kong
- Volunteers
- 397 people
- Sponsor
- The University of Hong Kong
Depression, Postpartum, Postpartum Care
Healing at Home 2.0 - Enhanced Chat Tool for Lowering Postpartum Depression
The purpose of the study is to determine if access to a text-message based holistic chatbot support program "Healing at Home 2.0" decreases depressive symptoms as measured by the Edinburgh Postnatal Depression Scale (EPDS)…
- Trial name
- HEALED (NCT06877104)
- Testing
- Healing @ Home Program (H@H 2.0)
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- University of Pennsylvania
Anxiety Disorders, Depressive Disorder
Islamic-Oriented vs. Standard Ericksonian Hypnotherapy for Anxiety and Depression
This randomized controlled trial (RCT) aims to compare the effectiveness of Islamic-Oriented Ericksonian Hypnotherapy (IEH) and Standard Ericksonian Hypnotherapy (SEH) in reducing symptoms of anxiety and depression.
- Trial name
- IEH-RTC (NCT06844058)
- Testing
- Islamic-Oriented Ericksonian Hypnotherapy (IEH), Standard Ericksonian Hypnotherapy (SEH)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
Premature Birth, Sedation During Labor and Delivery; Complications, Pulmonary
Magnesium for Neonatal Neuroprotection and Mothers
Magnesium is a treatment for mothers to protect brains of babies born early. This study investigates combined effects of magnesium and spinal or epidural anesthesia on mothers having cesareans.
- Conditions
- Premature Birth, Sedation During Labor and Delivery; Complications, Pulmonary, Respiratory Depression
- Trial name
- MnMs (NCT01482078)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of British Columbia
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