Clinical trials: Depression Diagnosis
Depression
Reboxetine Treatment in Depressed Children and Adolescents an 8-Week, Open Study
The aim of the present study is to prospectively assess the anti-depressant effectiveness of reboxetine in children and adolescents, as compared with fluoxetine, in a randomized controlled open-label trial.
- Trial name
- NCT00426946
- Testing
- Reboxetine
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Geha Mental Health Center
Chemotherapy Effect
Effect of Nurse-led Education on Parent's Anxiety and Depression on Managing Side Effects of Chemotherapy
ABSTRACT Background: Today, a wide range of pediatric cancers is treated by chemotherapy. More than 21 side effects of chemotherapy have been identified. Among those nausea; vomiting, infection and anemia are most common.
- Trial name
- NCT03753542
- Testing
- Multimedia education, booklet Providence and tele-nursing follow-up
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nomi Waqas Gul
Nicotine Dependence, Tobacco Use
Dissemination of a Tailored Tobacco Quitline for Rural Veteran Smokers
The project is designed to examine the effectiveness of strategies to increase access to treatment for tobacco use and dependence among rural Veteran smokers.
- Trial name
- NCT01892813
- Testing
- Nicotine replacement therapy - Transdermal nicotine patch, Nicotine replacement therapy - Nicotine gum, Nicotine replacement therapy - Nicotine lozenge
- Where
- United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Mark Vander Weg
Depressive Disorder, Treatment-Resistant
Treatment Resistant Depression in America Latina
The purpose of this study is to estimate the prevalence of Treatment Resistant Depression (TRD) among Major Depressive Disorder (MDD) participants being treated in a psychiatry reference site (example, clinic, ambulatory…
- Trial name
- TRAL (NCT03207282)
- Where
- 33 sites in Argentina, Brazil and 2 more
- Volunteers
- 1,539 people
- Sponsor
- Janssen-Cilag, S.A.
Major Depressive Disorder
Safety and Effectiveness of NeuroStar® Transcranial Magnetic Stimulation (TMS) Therapy in Depressed Adolescents
To evaluate the safety and efficacy of daily, active Neurostar® TMS (when compared with sham treatment) in adolescents meeting criteria for Major Depressive Disorder (MDD).
- Trial name
- NCT02586688
- Testing
- Active NeuroStar® Transcranial Magnetic Stimulation (TMS)
- Where
- 13 sites in United States
- Volunteers
- 112 people
- Sponsor
- Neuronetics
Knee Osteoarthritis (Knee OA)
Exercise-induced Irisin in Individuals With Knee Osteoarthritis.
The goal of this prospective randomised controled study is to investigate the effect of 8-weeks brisk walking exercise on irisin levels, physical and psychosocial parameters in individuals with knee osteoarthritis, and the…
- Trial name
- Osteoarthritis (NCT06758388)
- Testing
- home exercise program, home exercise program + brisk walking exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ümmahani Kuş
Depression - Major Depressive Disorder, Anxiety Disorders
AI-Guided CBT for Depression and Anxiety
This study aims to evaluate the effectiveness of an artificial intelligence (AI)-guided cognitive behavioral therapy (CBT) program for the treatment of mild depression and anxiety disorders in adults.
- Trial name
- AI-CBT-DA (NCT07576686)
- Testing
- AI-Guided Cognitive Behavioral Therapy, Cognitive Behavioral Therapy (CBT)
- Where
- Serbia
- Volunteers
- 120 people
- Sponsor
- Aleksandra Stojanovic
Bipolar Disorder, Depression
Positive Psychology for Mood Disorders
The investigators are doing this study to see if "positive psychology" can help adults with depression or bipolar disorder. Positive psychology involves exercises-short tasks-that try to increase good feelings and emotions, like…
- Trial name
- PPBPAD (NCT01820286)
- Testing
- Positive psychology intervention, Recollection intervention
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Premenstrual Syndrome, Premenstrual Dysphoric Disorder
EnBrace HR for PMS With Prominent Mood Symptoms or Menstrual Related Mood Disorders
The purpose of this study is to assess a novel nutritional supplement developed for prenatal health and mood benefits, and to determine whether there is preliminary evidence for efficacy in Menstrual Related Mood Disorders…
- Conditions
- Premenstrual Syndrome, Premenstrual Dysphoric Disorder, Premenstrual Tension, Menstrual Related Mood Disorder
- Trial name
- NCT04123483
- Testing
- EnBrace HR Softgel
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Chronic Back Pain, Chronic Pain
Active Coping: Interdisciplinary Program for Chronic Pain, Physiotherapy Unit (Spain)
The goal of this observational intervention study is to evaluate the impact of a multidisciplinary active coping program for chronic back pain in adults referred from Primary Care to the Physiotherapy Unit of Teruel Ensanche.
- Conditions
- Chronic Back Pain, Chronic Pain, Back Pain, Low Back Pain, Chronic
- Trial name
- NCT07504094
- Testing
- Pain Neuroscience Education (PNE), Healthy Habits and Psychological Intervention, Therapeutic Exercise
- Where
- 2 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Universidad de Zaragoza
Depression, Anxiety
Peripartum Mental Health Cohort Study in Guangzhou
The purpose of this study is to determine the incidence,development trajectory and risk factors of the main peripartum mental health problems as well as explore its adverse outcomes.
- Trial name
- NCT04499066
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Major Depressive Disorder, Opioid-use Disorder
rTMS for Suicidality in Opioid Use Disorder
This trial is a randomized, double blind, controlled pilot study that will compare bilateral theta burst stimulation (TBS) and sham treatment for patients with opioid use disorder (OUD) and Major Depressive Disorder (MDD)…
- Trial name
- NCT04785456
- Testing
- Active TBS
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Centre for Addiction and Mental Health
Fibromyalgia Syndrome, Anxiety
The Role of Bioelements in Fibromyalgia: Disease Activity or Depression-Anxiety?
The aim of this observational study was to determine the levels of serum bioelements in patients with fibromyalgia syndrome and to evaluate the relationship of these bioelements with disease activity, depression and anxiety.
- Conditions
- Fibromyalgia Syndrome, Anxiety, Depression
- Trial name
- NCT07519824
- Testing
- bioelements
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Major Depressive Disorder, Depression
rTMS for MDD: 5.5cm Rule vs. F3 Targeting
The purpose of this study is to examine the effects of different treatment locations using repetitive transcranial magnetic stimulation (rTMS) to treat major depressive disorder.
- Trial name
- NCT03378570
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Nicholas Trapp
Major Depressive Disorder, Irritable Bowel Syndrome
Neurocognitive Effects of FMT in MDD Patients With and Without IBS
This study is a phase 2/3 open-label controlled trial (CT) in which adults with Major Depressive Disorder (MDD) and adults who have MDD plus comorbid Inflammatory Bowel Syndrome (IBS) will be assigned to either receive oral Fecal…
- Trial name
- NCT05174273
- Testing
- Fecal Microbiota Transplantation
- Where
- Canada
- Volunteers
- 133 people
- Sponsor
- Valerie Taylor
Depression
Non-invasive Brain Stimulation Normalizes Dopaminergic Transmission in the Frontostriatal Circuit to Alleviate Depression With Metabolic Disorders.
Depression and metabolic disorder (MetD) are two of the most common and debilitating disorders worldwide, occurring with significant rates of comorbidity.
- Trial name
- NCT05117983
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Cheng-Kung University Hospital
Major Depressive Disorder
Regulated Stimulation for Optimized Network Activity and Therapeutic Equilibrium
The objective of this study is to evaluate the safety, tolerability, and preliminary efficacy of the Motif eXternally powered Cortical Stimulation (XCS) System when used as indicated for treatment-resistant depression (TRD).
- Trial name
- RESONATE (NCT07594483)
- Testing
- Motif XCS System
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- Motif Neurotech, Inc.
Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
Quality of Life, Functional and Cognitive Outcomes in Patients With Metastatic Hormone-Sensitive Prostate Cancer
This prospective observational study will evaluate quality of life, functional status, and cognitive outcomes in men with metastatic hormone-sensitive prostate cancer (mHSPC) receiving androgen receptor pathway inhibitors (ARPIs)…
- Trial name
- PRO-MIND (NCT07181122)
- Testing
- Androgen Receptor Pathway Inhibitors (ARPIs)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- Ankara Etlik City Hospital
Frailty at Older Adults, Post-Traumatic Stress Disorder in Old Age
Multimodal Intervention for Older Adults After an Earthquake
This randomized controlled study was conducted among older adults (≥65 years) living in temporary container housing in Kahramanmaraş after the February 2023 earthquakes.
- Conditions
- Frailty at Older Adults, Post-Traumatic Stress Disorder in Old Age, Depression in Adults, Malnutrition Elderly
- Trial name
- NCT07273253
- Testing
- Multimodal intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Depressive Symptoms, Generalized Anxiety
Efficacy of Therapist Guided e-Therapy Versus Self-Help Therapy on Psychological Distress Among Individuals in Oman During COVID-19 Pandemic
Background: COVID-19 (Corona Virus Disease 2019) is a virulent infectious disease with an incubation period ranging between 2-14 days.
- Trial name
- NCT04378257
- Testing
- Therapist Guided E-Therapy, Self-Help Therapy
- Volunteers
- 70 people
- Sponsor
- Sultan Qaboos University
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