Clinical trials: Depression Diagnosis
Craving, Depression, Anxiety
Non-invasive Brain Stimulation in Patients With Methamphetamine Use Disorder
The study aims to apply the intermittent theta burst transcranial magnetic stimulation (iTBS) treatment and evaluate the effect in improving craving, affective symptoms, and cognitive function for those participants in the…
- Conditions
- Craving, Depression, Anxiety, Amphetamine Addiction
- Trial name
- NCT05535101
- Testing
- Intermittent theta burst transcranial magnetic stimulation (iTBS)
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Major Depressive Disorder
Cognitive Training for Depression II
This study is evaluating the effects of two brain training exercises on: memory, cognitive processing and depression symptoms.
- Trial name
- NCT01934491
- Testing
- Cognitive Training A, Cognitive Training B
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Posture, Kyphosis
Effects of Telerehabilitation-based Motor Imagery and Exercise Combination in Individuals With Postural Kyphosis: A Randomized Controlled Trial
Objective: Kyphosis is one of the most common postural problems. It is defined as a thoracic curvature that exceeds normal limits.
- Conditions
- Posture, Kyphosis, Muscle Cramps, Thoracic Vertebrae
- Trial name
- NCT07122791
- Testing
- Home Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Istanbul University - Cerrahpasa
Schizophrenia, Caregiver Burden
Psychological Resilience and Quality of Life Among Caregivers of Patients With Schizophrenia
Schizophrenia is a severe and chronic psychiatric disorder that requires long-term care management, placing family members who serve as informal caregivers under substantial psychological, physical, and financial strain.
- Conditions
- Schizophrenia, Caregiver Burden, Quality of Life
- Trial name
- NCT07837479
- Volunteers
- 130 people
- Sponsor
- Assiut University
Major Depressive Disorder
Temporal Interference and Depression
Major Depressive Disorder (MDD) has a high prevalence, is the leading cause of disability, and currently available interventions are associated with side effects and high treatment resistance.
- Trial name
- TI (NCT05295888)
- Testing
- Temporal Interference stimulation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Unity Health Toronto
Depression, Anxiety, Trauma
Psychoeducation, Relaxation, PrOblem Solving, Activation, Cognitive Coping Therapy for Adolescents and Youth in HIV Care
The proposed PROACT study will test the effectiveness of a mental health intervention (psychotherapy) for multiple common mental health conditions (depressive, anxiety and trauma symptoms) among adolescents and youth with HIV in…
- Conditions
- Depression, Anxiety, Trauma, HIV-1-infection
- Trial name
- PROACT (NCT06247527)
- Testing
- Psychoeducation, Relaxation, PrOblem solving, Activation, Cognitive coping Therapy, Standard of care
- Where
- Kenya
- Volunteers
- 600 people
- Sponsor
- University of Nairobi
Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission
Internet-Based Program With or Without Telephone-Based Problem-Solving Training in Helping Long-Term Survivors of Hematopoietic Stem Cell Transplant Cope With Late Complications
RATIONALE: A personalized Internet-based program may help improve fatigue, depression, and quality of life in long-term survivors of stem cell transplant.
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
- Trial name
- NCT00799461
- Testing
- internet-based intervention, questionnaire administration, psychosocial assessment and care
- Where
- United States
- Volunteers
- 1,337 people
- Sponsor
- Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
Major Depressive Disorder
Melatonin Agonist Effects of Tasimelteon Versus Placebo in Patients With Major Depressive Disorder
The purpose of this study is to evaluate the safety and efficacy of an 8-week double-masked treatment of tasimelteon or placebo in male and female subjects with Major Depressive Disorder.
- Trial name
- MAGELLAN (NCT01428661)
- Testing
- tasimelteon
- Where
- 40 sites in United States
- Volunteers
- 507 people
- Sponsor
- Vanda Pharmaceuticals
Major Depressive Disorder
An Open Label Study of the Genecept™ Assay in Treatment Resistant Depression
The purpose of this study is to examine the potential impact of the assay in terms of depression severity as measured by change in Clinical Global Impressions (CGI) scale at 3 months.
- Trial name
- NCT01438242
- Testing
- Genecept Assay
- Where
- United States
- Sponsor
- Genomind, LLC
Anhedonia, Depression in Adults
Positive Affect Treatment for Spanish-Speaking Individuals
The purpose of this study is to evaluate the feasibility and acceptability of Positive Affect Treatment (PAT) in a Spanish-speaking population.
- Conditions
- Anhedonia, Depression in Adults, Anxiety
- Trial name
- NCT07493369
- Testing
- Positive Affect Treatment
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Southern Methodist University
Depression
Cognitive Control Training for Depression
Depression is frequently characterized by patterns of inflexible, maladaptive, and ruminative thinking styles; these patterns themselves are thought to result from a combination of decreased attentional control, decreased…
- Trial name
- NCT01454141
- Testing
- Cognitive Control Training, Peripheral Vision Task
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Stroke
Psychosocial/Behavioral Intervention in Post-Stroke Depression
The primary aim of this study is to determine the effect of a nurse-delivered psychosocial/behavioral intervention on reduction of depression in community dwelling post-stroke patients.
- Trial name
- NCT00194454
- Testing
- Modified cognitive behavioral therapy plus problem-solving, usual care
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- University of Washington
Long COVID
Evaluating the Effects of a Fermented Diet on Microbiome Diversity in Individuals With Long COVID
The purpose of this study is to evaluate the effects of fermented foods on bacterial gut microbiome diversity of long-COVID subjects.
- Trial name
- NCT06560554
- Testing
- Fermented foods, Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Perinatal Depression, Substance Use
Sober Network IPT for Perinatal Women With Comorbid Substance Use and Depression
This study will evaluate the effectiveness of Sober Network Interpersonal Psychotherapy (IPT) in treating women with depression and comorbid substance abuse.
- Trial name
- NCT01550913
- Testing
- Sober Network Interpersonal Psychotherapy (IPT), Treatment as Usual
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Anxiety Disorders, Depression
A Waitlist-Controlled Trial of the Unified Protocol for the Treatment of Emotional Disorders in Adolescents
This study will evaluate the effectiveness of an emotion-focused cognitive behavioral treatment program for adolescents with anxiety or unipolar depressive disorders.
- Trial name
- NCT00628888
- Testing
- Unified Protocol for Adolescents (UP-A)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Miami
Major Depressive Disorder
CARED : A Novel Rapid Treatment Paradigm for Depression
The purpose of this study is to primarily assess the feasibility and secondarily assess the efficacy of a single session intervention (SSI) that combines non-invasive brain stimulation and psychotherapy for Major Depressive…
- Trial name
- CARED (NCT07507370)
- Testing
- Intermittent Theta Burst Stimulation (iTBS), Transcranial Alternating Current Stimulation (tACS), Psychotherapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of North Carolina, Chapel Hill
Major Depression, Bipolar Disorder
Longitudinal Study of People Presenting for First Treatment of a Mood Disorder
The goal of this project is to study the course and outcome of illness in individuals who present with a first episode of depression or mania, or who have a recurrent disorder but have never received treatment.
- Trial name
- NCT01529905
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- McMaster University
Parkinson Disease, Depression
MST for Parkinson's Disease
This trial aims to test the feasibility of Magnetic Seizure Therapy (MST) for Depression in patients diagnosed with Parkinson's Disease.
- Conditions
- Parkinson Disease, Depression, Movement Disorders, Major Depressive Disorder
- Trial name
- MST-PD (NCT04784494)
- Testing
- Magnetic Seizure Theapy (MagPro XP MST)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Depression, Sleep Disorders, Circadian Rhythm
Longitudinal Ecological Study on Sleep-Wake Patterns in MDD Using Actigraphy
The proposed study will include a longitudinal ecological study (Study 1) and a randomised controlled trial (Study 2). The aims will be to (1) identify the sleep-wake profiles in individuals with Major Depressive Disorder (MDD)…
- Trial name
- NCT06233422
- Testing
- No intervention involved
- Where
- Hong Kong
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Major Depressive Disorder
Efficacy and Safety of Bupropion Hydrobromide in Adolescents and Children With Major Depressive Disorder
Double-Blind, Placebo-Controlled, Multicenter Study of Efficacy and Safety
- Trial name
- NCT02129751
- Testing
- bupropion hydrobromide
- Volunteers
- 246 people
- Sponsor
- Bausch Health Americas, Inc.
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