Clinical trials: Depression Diagnosis
Social Isolation, Depression
Discharge Functional Status and Rehospitalization in the Elderly
The DC PROMIS Study (also known as the Discharge Patient Reported Outcomes Measurement Information System Study) is a study to see the effect of patients' social, physical and mental function on their health after hospital…
- Conditions
- Social Isolation, Depression, Anxiety, Debility
- Trial name
- DC PROMIS (NCT02041585)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwestern University
Major Depressive Diorder, Early Life Trauma
Neurocircuitry Mechanisms and Efficacy of Lumateperone as Adjunctive Therapy for Major Depressive Disorder and History of Early Life Abuse
The purpose of this clinical research study is to understand how effective and safe an investigational study drug called lumateperone is and whether it works to reduce the severity of depressive symptoms in adults with Major…
- Trial name
- ITI-ELA-MDD (NCT07369115)
- Testing
- Lumateperone 42 mg
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas at Austin
Depression, Anxiety Disorders
School Withdrawal in Adolescents
The aim of the study is to evaluate the impact of the outpatient ambulatory child psychiatric care system on the functioning of anxio-depressive adolescents in school retreat by describing the modalities of individual psychic…
- Conditions
- Depression, Anxiety Disorders, Obsessive-Compulsive Disorder, Behavior Disorders
- Trial name
- DESCOL (NCT03904784)
- Testing
- school withdrawal teenagers
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Mobility, Depressive Symptoms
Effectiveness of AMICOPE Intervention to Maintain Self-Perceived Health and Intrinsic Capacity in Older People
In their day to day, persons do from simple to more or less complicated tasks and activities (ie: stand from a chair, open a door, shopping, read, drive, play chess, remind an appointment...).
- Conditions
- Mobility, Depressive Symptoms, Nutrition, Healthy, Cognitive Decline
- Trial name
- EFICIS (NCT05249504)
- Testing
- VIVIFRAIL, Nutrition, Psychology
- Volunteers
- 212 people
- Sponsor
- Fundacio Salut i Envelliment UAB
Major Depressive Disorder
Use of Multiple Brain Imaging Modalities (PET and MRS) to Identify Metabolic Abnormalities in Major Depression
Several lines of evidence support the existence of an underlying abnormality in brain energy metabolism may play a key role in the biology of mood disorders.
- Trial name
- NCT01465165
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Paul Carlson
Bipolar Disorder, Depression
Depression, Obesity and Inflammatory Markers
The purpose of this study is to better understand the relationship between bipolar disorder, body weight, and inflammation in the body (N=180).
- Conditions
- Bipolar Disorder, Depression, Obesity
- Trial name
- NCT02765100
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Weill Medical College of Cornell University
Depression
Measuring Quality of Decisions About Treatment of Depression
The purpose of this randomized controlled trial is to examine the impact of a patient decision aid on the quality of decisions about managing symptoms of depression.
- Trial name
- NCT01152307
- Testing
- DVD/Booklet: Coping with Symptoms of Depression
- Where
- United States
- Volunteers
- 405 people
- Sponsor
- University of Massachusetts, Boston
Anxiety, Depression
ACT for Distress in Head and Neck Cancer Patients
Title: Acceptance and Commitment therapy for Individuals with Head and Neck Cancer Experiencing Psychological Distress. Head and neck cancer (HNC) patients are particularly vulnerable to experiencing psychological distress .
- Trial name
- NCT02840071
- Testing
- Psychological therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 3 people
- Sponsor
- University of Nottingham
Depression, Involutional, Major Depresssion
Rapid Antidepressant Effects of Yohimbine in Major Depression
This study examines if Yohimbine, when given during the sleep cycle, will improve symptoms of depression within a matter of hours.
- Trial name
- NCT00078715
- Testing
- Yohimbine hydrochloride
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- National Institute of Mental Health (NIMH)
Depression, Anxiety
Mental Health Impact of the COVID-19 Pandemic on Amish and Mennonite Participants in AMBiGen
People have had to make a lot of changes to their lives due to the COVID-19 health crisis. Most experts agree that social distancing and other safety measures have taken a toll on people s mental health.
- Conditions
- Depression, Anxiety, Bipolar Disorder
- Trial name
- NCT04684615
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Depression
Trial to Determine the Maximum Tolerated Dose (MTD) Based on Safety and Tolerability, of Org 26576 in Participants With Major Depressive Disorder (174001/P05704/MK-8777-001)
Trial to determine the maximum tolerated dose (MTD) based on safety and tolerability of MK-8777 (Org 26576, SCH 900777) in participants with major depressive disorder.
- Trial name
- NCT00610649
- Testing
- MK-8777
- Volunteers
- 54 people
- Sponsor
- Merck Sharp & Dohme LLC
Cognitive/Functional Effects, Delirium
Donepezil and Vitamin E to Prevent Side Effects Caused By Radiation Therapy to the Head in Patients Receiving Treatment for Small Cell Lung Cancer
RATIONALE: Donepezil and vitamin E may be able to decrease side effects caused by radiation therapy given to prevent brain metastases in patients with small cell lung cancer.
- Conditions
- Cognitive/Functional Effects, Delirium, Depression, Lung Cancer
- Trial name
- NCT00006349
- Testing
- vitamin E, donepezil hydrochloride
- Where
- 15 sites in United States
- Volunteers
- 9 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Primary Insomnia, Depressive Disorders With Insomnia
Enhancing Performance of Cognitive Behavioral Therapy for Insomnia With an Integrative Mobile Platform
Cognitive Behavioral Therapy for Insomnia (CBT-I) has been proven as an effective intervention for the non-pharmacological treatment of insomnia.
- Trial name
- NCT01978626
- Testing
- App modules, Traditional CBT-I
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Insomnia Chronic, Insomnia
Effects of Insomnia Treatment on Metabolism in Patients With Depression
This project will examine changes in metabolism and depressive symptoms after receiving CBT-I in 30 subjects with insomnia disorder and MDD.
- Conditions
- Insomnia Chronic, Insomnia, Insomnia, Primary, Depression
- Trial name
- NCT04719143
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pennsylvania
Post Partum Depression
Effectiveness of Thinking Healthy Program for Prevention of Antenatal Depression
The trial is to evaluate the effect of an evidence-informed, depression focused early prenatal prevention intervention at six weeks' postpartum.
- Trial name
- PAD (NCT04663243)
- Testing
- Thinking healthy Program sessions designed for antenatal period
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of the Punjab
Emotional Distress, Burnout, Professional
A Self-directed Mobile Mindfulness Intervention to Address Distress and Burnout in Frontline Healthcare Workers
This is a pilot randomized waitlist control trial assessing if the feasibility of using a mobile mindfulness app to treat emotional distress and burnout amongst nurses taking care of COVID-19 patients.
- Conditions
- Emotional Distress, Burnout, Professional, Stress, Job, Anxiety
- Trial name
- LIFT-HCW (NCT04816708)
- Testing
- LIFT Mindfulness
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Duke University
Traumatic Brain Injury, Depression
Life Improvement Following Traumatic Brain Injury
The purpose of this study is to test the effectiveness of a telephone-based and in-person Cognitive Behavioral Therapy (CBT) intervention for treating Major Depressive Disorder (MDD) following Traumatic Brain Injury.
- Trial name
- LIFT (NCT00878150)
- Testing
- In-person Cognitive Behavioral Therapy, Telephone Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Schizophrenia, Schizoaffective Disorder
Virtual Reality Job Interview Training in Severe Mental Illness
This is a randomized controlled trial to evaluate the community-based effectiveness of virtual reality job interview training (VR-JIT). Northwestern University is partnering with Thresholds Inc.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Depressive Disorder
- Trial name
- NCT03049813
- Testing
- Virtual Reality Job Interview Training, Supported Employment (Services as Usual)
- Where
- 4 sites in United States
- Volunteers
- 168 people
- Sponsor
- University of Michigan
Cardiovascular Diseases, Heart Diseases
Epidemiology of Cardiovascular Risk Factors in Women (Healthy Women Study)
To determine cardiovascular risk factors and the change in risk factors during and following the menopause.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Depression, Carotid Artery Diseases
- Trial name
- NCT00005160
- Volunteers
- 532 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
HIV, Insomnia
Effect of Dolutegravir Compared With Darunavir/Cobicistat on the Severity of Neuropsychiatric Effects al 12 Weeks in Antirretroviral Treatment-Naive Adults.
This clinical trial aimed at evaluating changes in neuropsychiatric scales for depression, anxiety, insomnia, and sleep quality in people living with HIV (PLHIV) who initiate antiretroviral therapy (ART) with a regimen of…
- Conditions
- HIV, Insomnia, Anxiety
- Trial name
- MORFEO (NCT06787976)
- Testing
- Dolutegravir (DTG), Darunavir/Cobicistat (FDC)
- Volunteers
- 140 people
- Sponsor
- Instituto Mexicano del Seguro Social
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