Clinical trials: Depression Disorders
Chronic Pain, Depression, Anxiety
Evaluating the Psychophysiological Effects of a Smartphone-Based Mindfulness Task
The aim of the present study is to evaluate the psychophysiological effects of a smart phone based mindfulness meditation app (MMA) for individuals with clinically significant symptoms of major depression and/or anxiety, or…
- Trial name
- NCT03296007
- Testing
- Mindfulness Meditation
- Where
- Canada
- Volunteers
- 2,016 people, healthy volunteers welcome
- Sponsor
- York University
Mental Health, Depression
Designing a Mobile App to Support Academic Success for Student Veterans
Compared to civilian students in higher education, student Veterans have high rates of mental health disorders (e.g., Depression: 24% vs 12.1%).
- Conditions
- Mental Health, Depression, Post-Traumatic Stress Disorder, Anxiety
- Trial name
- NCT05344092
- Testing
- VetEd Mobile Application
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Breastfeeding, Postnatal Depression
Mother and Late Preterm Lactation Study
Breastfeeding has various benefits for the mother and infant. It has the capability of reducing the risk of short term and long term problems for the infant, such as gastroenteritis, respiratory infections, type II diabetes and…
- Conditions
- Breastfeeding, Postnatal Depression, Stress, Psychological, Preterm Infant
- Trial name
- MAPLeS (NCT03791749)
- Testing
- Breastfeeding Support
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University College, London
Anhedonia, Depression
Sleep and Healthy Aging Research on Depression for Younger Women
Compelling evidence indicates inflammation plays a role in depression, but potential mechanisms linking inflammation to depression, such as dysregulated reward processing, are poorly understood.
- Trial name
- NCT03848715
- Testing
- Endotoxin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Stress Disorders, Post-Traumatic, Depressive Disorder, Major
The Effect of Traumatic Childbirth on the Incidence of PTSD and Other Major Postpartum Psychopathology
Determination of incidence and prevalence of PTSD and other types of psychopathology (such as anxiety and affective disorders) after traumatic birth experiences and elucidation of salient risk factors in the local population…
- Trial name
- NCT02370576
- Testing
- rating scale application
- Where
- Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Major Depressive Disorder, Treatment Resistant Depression
Antidepressant Effects of Nitrous Oxide
To evaluate the acute and sustained antidepressant effects of nitrous oxide in people with major depressive disorder; and further evaluate these effects by identifying the optimal dose and regimen to guide current practice, and…
- Trial name
- NCT05357040
- Testing
- Nitrous oxide gas for inhalation
- Where
- 2 sites in United States, Australia
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago
Depression, Sleep
Exergame on Sleep and Emotion Among Students
This study aims to investigate the feasibility and the potential efficacy of using Xbox 360 Kinect game among healthcare undergraduate students.
- Conditions
- Depression, Sleep, Anxiety, Stress
- Trial name
- NCT03906396
- Testing
- Xbox 360 Kinect
- Where
- Malaysia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Laughter Therapy, Psychological Well-being
Effect of Laughter Therapy on Breast Cancer Patients
The aim of this study is to examine the effect of laughter therapy applied to breast cancer patients before surgical intervention on distress, depression and psychological well-being of patients.
- Conditions
- Laughter Therapy, Psychological Well-being, Breast Cancer, Distress
- Trial name
- NCT07020962
- Testing
- laughter therapy, routine nursing care
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Anxiety
Feasibility Study of a Music and Social Support Intervention for Postnatal Mothers/Infants
This research study aims to assess the feasibility of conducting a full scale trial of Mamas in Harmony, a group music and social support class delivered by a professional musician for mothers and their babies.
- Trial name
- NCT05930990
- Testing
- Mamas in Harmony
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Mental Disorder, Schizophrenia
A Trial to Assess a Wearable Patch's Functioning to Detect Medication Ingestion
The primary purpose of the study is to evaluate the positive detection accuracy (PDA) and detection latency measures of the D-Tect patch.
- Conditions
- Mental Disorder, Schizophrenia, Major Depressive Disorder, Bipolar I Disorder
- Trial name
- NCT06372210
- Testing
- Abilify MyCite®, D-Tect Patch
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Mental Disorders, Mood Disorders
PET Neuroimaging of [11C]Mirtazapine
Recent studies show that 25 - 30% of depressed patients never fully recover, resulting in a treatment-resistant condition. Thus, depression is a major cause of human suffering.
- Conditions
- Mental Disorders, Mood Disorders, Affective Disorders, Depressive Disorders
- Trial name
- NCT00288782
- Testing
- Mirtazapine
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Mood Disorders, Major Depressive Diorder
Validation of Wearable Core Body Temperature-Based Circadian Rhythm Digital Biomarkers
This single-site prospective observational study aims to validate wearable-derived circadian and behavioral rhythm biomarkers using continuous core body temperature and raw accelerometry measurements and to explore longitudinal…
- Conditions
- Mood Disorders, Major Depressive Diorder, Bipolar Disorders, Mental Disorder
- Trial name
- Calera (NCT07905378)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Anhedonia, Depression
A Neurobiological Model of Anhedonia
The purpose of this research study is to better understand anhedonia in Major Depressive Disorder by investigating the reward-related neural and inflammatory correlates.
- Trial name
- NCT05629520
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Wellness, Quality of Life
Assessing the Effectiveness of Digital Wellness Modules on Perceived Quality of Life
The study will examine the role of digital wellness modules (brief mindfulness and light to moderate physical exercise) delivered through a smartphone wellness application and their short-term effects on health behavior…
- Conditions
- Wellness, Quality of Life, Anxiety, Depression
- Trial name
- NCT05810259
- Testing
- Caravan Wellness app
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yale University
Major Depressive Disorder (MDD)
Validation of Accexible as a Tool for Screening and Monitoring Depression.
Major depressive disorder (MDD) is a chronic disease with a prevalence around 8-12% and is considered one of the most debilitating disease worldwide.
- Trial name
- NCT06044818
- Testing
- Accexible
- Where
- Spain
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Accexible
Depression
Intravenous Ketamine Effects on Functional Neuroanatomy
The purpose of this study is to investigate the neuroanatomical effects of ketamine treatment on patients with treatment-resistant depression.
- Trial name
- NCT04205890
- Testing
- Ketamine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Neurological Associates of West Los Angeles
Depressive Disorder
European Comparative Effectiveness Research on Internet-based Depression Treatment
To compare the clinical impact and cost-effectiveness of blended Cognitive Behavioural Therapy (CBT) for adults with major depressive disorder (MDD) with treatment as usual (TAU).
- Trial name
- E-COMPARED (NCT02542891)
- Testing
- Blended CBT, Treatment as Usual (TAU)
- Where
- 10 sites in France
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Post Traumatic Stress Disorder, Insomnia
RESILIENT - An Online Multidimensional Treatment to Promote Resilience After a Disaster: Randomized Controlled Trial Protocol
Background. The wildfires on May 1, 2016 in Fort McMurray, Alberta (Canada), destroyed approximately 2,400 homes and buildings and led to massive displacement of approximately 88,000 people.
- Conditions
- Post Traumatic Stress Disorder, Insomnia, Depression
- Trial name
- RESILIENT (NCT04808713)
- Testing
- Treatment
- Where
- Canada
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Laval University
Severe Major Depression Disorder
Neurochemical, Metabonomics and Neuroimaging Characterization of TCM Diagnostic Subtypes of Major Depression Disorder
There is heterogeneity in patients with depression. Many scholars propose that individualization of antidepressant achieves better outcomes.
- Trial name
- NMNTDM (NCT02346682)
- Testing
- venlafaxine
- Where
- China
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Zhejiang Provincial Tongde Hospital
Mental Health Issue
Effects of Cognitive-Oriented Intervention on Major Depressive Disorder
The specific aims of the study were to explore the effects of the cognitive-oriented intervention program for promoting social support on perceived social supports, depression symptoms, and stress-coping strategies for patients…
- Trial name
- NCT05296174
- Testing
- cognitive-oriented intervention program, health education activities program
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Mackay Medical College