Clinical trials: Depression Moderate
Depression Mild, Depression Moderate
Factorial Trial Investigating Outcome and Adherence Relevant Factors in an Online Self-help Intervention for Depression
A vast amount of studies show that online interventions are suitable to reduce symptoms of mental illness as for instance depression or anxiety.
- Trial name
- HERMES (NCT04318236)
- Testing
- HERMES (Online Self-Help Intervention based on problem-solving therapy)
- Where
- Switzerland
- Volunteers
- 316 people
- Sponsor
- University of Bern
Anxiety, Mild to Moderate Depression
Trial of Prompt Mental Health Care
Anxiety and depression are among the most common mental disorders in the population. Anxiety and depression have significant consequences at the individual, family and community level, and mental illness is estimated to cost the…
- Trial name
- NCT03238872
- Testing
- Cognitive Behavioural Therapy, Treatment as usual
- Where
- 2 sites in Norway
- Volunteers
- 774 people
- Sponsor
- Norwegian Institute of Public Health
Moderate Depression
The Impact of Spiritual Healing on Moderate Depression in Adults
Depression is a common mental disorder and is together with anxiety the global leading cause of all non-fatal burden of disease.
- Trial name
- NCT04766242
- Testing
- Spiritual healing, Usual care
- Where
- Norway
- Volunteers
- 28 people
- Sponsor
- University of Tromso
Moderate Dementia, Severe Dementia
Can Virtual Reality Reduce Depression and Agitation in Older Adults With Moderate to Severe Dementia?
Dementia is a term used to describe a collection of symptoms including memory loss, problems with reasoning and communication, and a reduction in a person's ability to carry out daily activities.
- Trial name
- NCT04347668
- Testing
- Virtual Reality, Usual Care
- Where
- 3 sites in Canada
- Volunteers
- 266 people
- Sponsor
- Western University, Canada
Moderate Depressive Episodes (Major Depression)
Study to Learn About Relapse Prevention of Hypericumextract (a Drug Based on the Plant St. John Wort) in Outpatients Suffering From Moderate Depressive Episodes
The researchers in this trial want to learn more about the drug Laif® 900 in preventing the return of signs and symptoms of depressions (also called relapse) in patients suffering from moderate depression episodes.
- Trial name
- NCT04315597
- Testing
- Laif® 900, BAY98-7108
- Volunteers
- 398 people
- Sponsor
- Bayer
Pregnancy, Moderate Depression
Effects and Consequences for Mother and Child From Treatment for Depression
This study targets women with moderate depression during pregnancy. We aim to investigate the direct effect of the newborn child and the long term consequences on the cognitive developement on children who´s mother has been…
- Trial name
- MAGDALENA (NCT02185547)
- Testing
- Zoloft, ICBT
- Where
- Sweden
- Volunteers
- 17 people
- Sponsor
- Katarina Wide
Depression Moderate, Depression Mild
Cognitive Behavioral Therapy-Based Group Counseling
The university environment presents a valuable opportunity to reach the young population of society, which has a high risk of depression, and to provide protective mental-health services.
- Trial name
- CBTBGC (NCT04192721)
- Testing
- Cognitive Behavioral Therapy-Based Group Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Gazi University
Depression, Depressive Disorder, Major
Sleep, Wake and Light Therapy for Depression
The aim of this study is to determine if altering the pattern of one's sleep and having light therapy can speed up the treatment of depression.
- Conditions
- Depression, Depressive Disorder, Major, Depression, Unipolar, Depression Moderate
- Trial name
- NCT03405493
- Testing
- Wake and Light Therapy, Sleep and Light Therapy
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- King's College London
Moderate Depression
Reducing Depressive Symptomatology With a Smartphone App
The aim of this study is to test a newly developed app, firmly grounded in Cognitive Behavioural Therapy (CBT) theory of depression, to determine primarily if this app is clinically useful in decreasing moderate depressive…
- Trial name
- NCT03060200
- Testing
- Self-administered online CBT plus therapist check in
- Where
- Romania
- Volunteers
- 158 people
- Sponsor
- Babes-Bolyai University
Mild to Moderate Depression
Pilot Study Using Transcranial Electrostimulation (TESA-HB) Therapy for the Treatment of Depressive Symptoms
This pilot study uses TESA-HB therapy for treatment of depressive symptoms associated with mild and moderate depression episodes.
- Trial name
- TESAHBPilot (NCT03471754)
- Testing
- TESA-HB Transcranial Electronic Stimulation Device
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Annecto LLC
Mild-moderate Unipolar Depression; Persistent Negative Affect
Dismantling Mindfulness: Contributions of Attention vs. Acceptance
This study addresses NCCAM's request for research that investigates the neuropsychological mechanisms underlying mind-body therapies, and for precise criteria and better delineation of meditation practices.
- Trial name
- NCT01831362
- Testing
- Mindfulness-Based Cognitive Therapy, Focused Attention (FA), Open- Monitoring
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Brown University
Mild to Moderate Depression
Management Strategy for Mild to Moderate Major Depression: Combination of Rhodiola and Saffron Extracts.
The purpose of the study is to describe, over 6 weeks, the evolution of depressive symptoms in patients with mild to moderate major depression in a strategy with Phytostandard® Rhodiola-Saffron supplementation
- Trial name
- NCT02981225
- Testing
- Phytostandard® Rhodiola-Saffron
- Where
- France
- Volunteers
- 59 people
- Sponsor
- PiLeJe
Long-term Physical Health Conditions, Mild to Moderate Anxiety and/or Depression
A Component Analysis of Acceptance and Commitment Therapy
The purpose of this study is to determine whether a specific component of Acceptance and Commitment Therapy (ACT) called 'Self as Context' is an important and necessary part of this therapeutic approach.
- Trial name
- NCT02162030
- Testing
- Acceptance and Commitment Therapy
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of Sheffield
Moderate Depression, Clinical Depression
Task Sharing Counseling Intervention by Community Health Workers for Prenatal Depression in South Africa
The objective of this randomised controlled trial (RCT) is to determine the effectiveness and cost-effectiveness of a task sharing counseling intervention for maternal depression in South Africa(i.e.
- Conditions
- Moderate Depression, Clinical Depression, Postpartum Depression
- Trial name
- AFFIRM-SA (NCT01977326)
- Testing
- basic counselling by lay-health workers, Enhanced usual care
- Where
- 2 sites in South Africa
- Volunteers
- 4,205 people
- Sponsor
- University of Cape Town
Patients With Moderate Depression,, First or Second Episode
Feasibility and Acceptability of an Educational Intervention to Improve the Management of Depression in Primary Care.
Qualitative study based on interviews and questionnaires with patients participating to an educational intervention to improve the management of depression in primary care.
- Trial name
- NCT01284803
- Testing
- an educational intervention
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Moderate Depression, Menopausal and Postmenopausal Disorders
Homeopathic Treatment for Depression in Peri- and Postmenopausal Women
The aim of this study was to determine whether individualized homeopathic treatment and fluoxetine are more efficient than placebo for moderate to severe depression in peri- and postmenopausal women.
- Trial name
- HOMDEP-MENOP (NCT01635218)
- Testing
- Individualized homeopathic treatment, Fluoxetine
- Where
- Mexico
- Volunteers
- 133 people
- Sponsor
- Hospital Juarez de Mexico
Mild to Moderate Depression.
Cost-effectiveness of a Non-Pharmacological Treatment (Active Monitoring) vs. a Pharmacological Treatment for Major Depression in Primary Care.
Major Depression (MD) is highly prevalent and has associated a high burden and economic costs. Mild levels of MD could be treated without antidepressants at Primary Care (PC).
- Trial name
- NCT02245373
- Testing
- Antidepressants, Active Monitoring
- Volunteers
- 263 people
- Sponsor
- Fundació Sant Joan de Déu
Severe Asthma, Moderate or Severe Major Depressive Disorder
Treatment of Outpatients With Severe Asthma and Moderate or Severe Major Depressive Disorder
The purpose is to determine if: 1) Escitalopram treatment will be associated with less oral corticosteroid use than placebo in outpatients with severe asthma and moderate or severe major depressive disorder (MDD).
- Trial name
- NCT00621946
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Texas Southwestern Medical Center
Restless Legs Syndrome, Moderate to Severe Idiopathic Restless Legs Syndrome (RLS)
The Effects Of Ropinirole On Mood Or Mild Depression In Patients With Moderate To Severe Restless Legs Syndrome
Ropinirole has shown to improve mood in depressed patients as well as to improve the symptoms of Restless Legs Syndrome. Up to 40% of RLS patients suffer from mild depression, therefore it would be important for decisions no…
- Trial name
- NCT00357097
- Testing
- Ropinirole
- Where
- 50 sites in Germany
- Volunteers
- 240 people
- Sponsor
- GlaxoSmithKline