Clinical trials: Depression NOS
Depression, Depressive State
A Study to Compare the Pharmacokinetic Profiles of Etravil® Tablet 10mg and Etravil® Tablet 25mg
To evaluate the pharmacokinetics of single oral dose of Amitriptyline hydrochloride film-coated tablet 10mg \& 25mg
- Conditions
- Depression, Depressive State, Enuresis
- Trial name
- DWETR (NCT01367080)
- Testing
- DWETR10, DWETR25
- Where
- South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Dong Wha Pharmaceutical Co. Ltd.
Suicide and Depression, Psychological Distress
Preventing Psychological Distress and Suicidal Behaviours: a Web-based and Mobile Suicide Prevention Intervention in the General Population
An interventional research study will be undertaken to assess the effectiveness of the promotion at the local level of an e-health tool for suicide and psychological distress prevention (the StopBlues application and website).
- Conditions
- Suicide and Depression, Psychological Distress, Anxiety Disorders, Local Authorities Promotion
- Trial name
- PRINTEMPS (NCT03565562)
- Testing
- Promotion of the e-health tool by local authorities, Promotion of the e-health tool by local authorities and GPs
- Where
- France
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Breast Cancer, Lung Cancer
Developing a Virtual Stress Management Intervention for Spousal/Partnered Caregivers of Solid Tumor Cancer Patients.
This randomized control trial will investigate the ability of an effective stress management psychoeducation program for employed caregivers to mitigate psychological distress and pathophysiology in spousal or partnered…
- Conditions
- Breast Cancer, Lung Cancer, Colon Cancer, Solid Tumor, Adult
- Trial name
- eCare (NCT04739696)
- Testing
- PEPRR, Pep-Pal
- Where
- United States
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Depressive Symptoms, Anxiety
Evaluation of Mindfulness and Yoga in Basic Combat Training
The present study is a group randomized trial assessing the impact of mindfulness and yoga training on the health, performance, and well-being of soldiers in Basic Combat Training (BCT).
- Conditions
- Depressive Symptoms, Anxiety, Sleep, Emotion Regulation
- Trial name
- NCT05550610
- Testing
- Mindfulness Based Attention Training (MBAT) and Yoga
- Where
- United States
- Volunteers
- 1,896 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)
Breastfeeding, Paternal Behavior
Paternal Involvement in Breastfeeding
Paternal involvement in breastfeeding has been identified as a significant predictor in maternal breastfeeding outcomes. The main aim of this study is to examine the relationship between reported paternal breastfeeding support…
- Conditions
- Breastfeeding, Paternal Behavior, Depression
- Trial name
- NCT05064982
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Marmara University
Depressive Symptoms
Online Intervention for Depression: MOOD
The study aims to examine the efficacy and acceptance of a self-help internet intervention "MOOD" in a sample of individuals with depressive symptoms.
- Trial name
- MOOD (NCT03795480)
- Testing
- MOOD
- Where
- Germany
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Respiratory Depression
ENA-001 for Opioid Induced Respiratory Depression
This study is a Phase I clinical trial to assess the safety, tolerability, and pharmacokinetic (PK) and pharmacodynamic (PD) profiles with single intravenous (IV) and intramuscular (IM) doses of ENA-001.
- Trial name
- NCT06967259
- Testing
- ENA-001
- Where
- 2 sites in United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Enalare Therapeutics Inc.
Stroke
Online Mindfulness for Stroke Sufferers
A feasibility study to investigate the effect of an online mindfulness programme (www.bemindfulonline.com) on stroke survivors' mental and physical wellbeing.
- Trial name
- NCT03368950
- Testing
- Online Mindfulness Course
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Depression, Anxiety Disorders
SKY Breath Intervention
Depression is highly debilitating and prevalent among adolescents. Adolescent-onset depression is associated with long, severe, and recurrent episodes that are often not responsive to treatment.
- Trial name
- NCT05388110
- Testing
- SKY Breath Intervention
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Depression
LTP Plus Dads-Partner Inclusive Intervention for Depressed Fathers in Pakistan
The aim of this study is to support and equip fathers and mothers with cognitive behavioral tools and knowledge about child development to be effective in their role as co-parent and partner, leading to improvement in paternal…
- Trial name
- LTP+Dads (NCT05036720)
- Testing
- LTP+Dads, LTP+ Optional mother component
- Where
- Pakistan
- Volunteers
- 2,884 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Living and Learning
Mental State, Reported as Depression, Anxiety or Stress
The Impact of Giving a Massage
The aim of this study is to investigate if giving a massage impacts the mental state of a massage therapist, including depression, anxiety, and stress .
- Trial name
- NCT01169480
- Testing
- Give a massage
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Parker Research Institute
Dementia, Depression
Pilot Study to Examine Health Effects of Daylight Exposure on Dementia Patients
This study is designed to test the hypothesis that an intervention increasing exposure to daylight indoors will reduce depression and other neuropsychiatric symptoms among people living with dementia in long term care facilities.
- Conditions
- Dementia, Depression, Behavior Disorders
- Trial name
- NCT03483896
- Testing
- Daylight Intervention
- Where
- 8 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Premature Birth, Pregnancy Preterm
Engaging Mothers & Babies; Reimagining Antenatal Care for Everyone (EMBRACE) Study
This is a randomized comparative effectiveness study of two forms of enhanced prenatal care among 674 Medi-Cal eligible pregnant individuals in Fresno, California.
- Conditions
- Premature Birth, Pregnancy Preterm, Prenatal Stress, Depression, Anxiety
- Trial name
- EMBRACE (NCT04154423)
- Testing
- Glow! Group Prenatal Care, Individual Prenatal Care with CPSP
- Where
- 2 sites in United States
- Volunteers
- 678 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Depression, Bipolar Disorder
Neuro-computational Study of Thymic Fluctuations in Mood Disorders
Depression and bipolar disorder are frequent, debilitating conditions. Both are thought to be primarily caused by an impaired regulation of mood, which is why they are sometimes referred to as "mood disorders".
- Conditions
- Depression, Bipolar Disorder, Recurrent Depression, Mood Disorders
- Trial name
- MOODELING (NCT07033923)
- Testing
- Brain magnetic resonance imaging (MRI) with structural (anatomical) and functional sequences (optional), Computerized cognitive tests, Daily longitudinal monitoring by mobile MOODELING application
- Where
- 2 sites in France
- Volunteers
- 588 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Depression, Depressive Disorder
Metformin as Adjunct Therapy in Depression-obesity Comorbidity: Clinical and Genetic Evaluation
The patients with depression and obesity will receive add-on metformin with antidepressant therapy, which may result in greater improvement in depressive symptoms and BMI reduction compared to antidepressant monotherapy.
- Conditions
- Depression, Depressive Disorder, Overweight or Obesity, Depressive Symptoms
- Trial name
- NCT07654179
- Testing
- Metformin, Antidepressant Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Prolonged Pregnancy, Sleep Disturbance
Sleep and Depression in Induction of Labour
Randomised trial comparing double balloon catheter for induction of labor between inpatient and outpatient groups. The investigators assess how sleep disturbances and depression of the mother affect to the pain during balloon…
- Conditions
- Prolonged Pregnancy, Sleep Disturbance, Depression
- Trial name
- NCT03380897
- Testing
- Intervention for outpatient group was to go home, Intervention for inpatient group was to stay at ward
- Where
- Finland
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Diabetes, Pre-diabetes
Northern Manhattan Study of Metabolism and Mind
Pre-diabetes, type 2 diabetes, and their related conditions, adiposity and insulin resistance, are more prevalent in minorities Northern Manhattan compared to the general population of the United States.
- Conditions
- Diabetes, Pre-diabetes, Cognition - Other, Depressive Symptoms
- Trial name
- NOMEM (NCT02470260)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Resident Wellness, Resident Burnout
Remote Physiologic Monitoring of Resident Wellness and Burnout
Resident wellness and physician burnout are under the spotlight more and more as data begins to show that there is a point of diminishing return on the number of hours in training.
- Conditions
- Resident Wellness, Resident Burnout, Sleep, Stress
- Trial name
- NCT04304703
- Testing
- WHOOP strap 3.0
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Depressive Symptoms, Sleep Disturbance
Effects of Exercise Intervention on Sleep Quality and Emotional Problems in College Students With Depressive Symptoms
This exploratory randomized controlled trial aims to investigate the immediate and long-term effects of exercise on sleep quality, emotional problems, executive function, and neurophysiological characteristics in college students…
- Trial name
- NCT07738809
- Testing
- Archery Exercise, Non-exercise Control
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Capital University of Physical Education and Sports, China
Depression, Major Depressive Disorder
Noninvasive Physiologic Sensors to Assess Depression
This project aims to use sensors to monitor physiological signals, sleep patterns, vocal characteristics, activity, location and phone usage in study patients with depression who are receiving standard treatment (compared with…
- Trial name
- NCT02568865
- Testing
- Physiological Sensors, Sleep Monitoring Device, Vocal Monitoring
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
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