Clinical trials: Depression NOS
Bipolar Disorder Depression, Major Depression
AI-based Multi-center Research on Identification/Classification/Aided Diagnosis of Mood Disorder
At present, diagnosis and recognition of depression and bipolar disorder are mainly based on subjective evidence such as clinical interview and scale evaluation.
- Trial name
- NCT05608135
- Where
- China
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Mental Health Issue, Cognitive Symptom
PrimeCog: Primary Care Cognitive Testing
The PrimeCog study aims to describe the symptomatology and pathophysiology of stress-induced exhaustion disorder (SED) and major depressive disorder (MDD) compared to healthy controls (HC).
- Conditions
- Mental Health Issue, Cognitive Symptom, Primary Health Care
- Trial name
- PrimeCog (NCT06346535)
- Testing
- Cognitive Testing
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Region Östergötland
Chronic Low-back Pain, Depression
Pain Neuroscience Education for Depression
This study will look at the effects of Pain Neuroscience Education on a Depression outcome tool in patients with chronic low back pain.
- Trial name
- PNEdepress (NCT04023435)
- Testing
- PNE edcuation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St. Ambrose University
Dementia
Cognitive Stimulation Therapy for Dementia
Aim: The aim of this study is to reveal the effectiveness of cognitive stimulation therapy on activities of daily living, depression and life satisfaction in individuals with mild dementia living in nursing homes.
- Trial name
- NCT05514678
- Testing
- Cognitive Stimulation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ejdane Coskun
Treatment Resistant Depression
Linear Asymmetric rTMS in Adolescent Treatment-Resistant Depression: Treatment Durations From Ten Days to One Day
This is a pilot interventional study to investigate the acceptability, tolerability, and side effect profile for varying numbers of treatment sessions/day of a new rTMS treatment in adolescents with treatment-resistant depression…
- Trial name
- NCT03986658
- Testing
- Linear Asymmetric rTMS System
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- NeuroQore Inc.
Mental Health Wellness 1
The Psychological Impact of the COVID-19 on Students.
The COVID-19 outbreak has been rapidly transmitted in late January 2020 and aroused enormous attention globally. The public at large may also experience boredom, disappointment, and irritability under the isolation measures.
- Trial name
- NCT04365361
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Postpartum Depression
Does Enhancing Maternal Peer Interactions Decrease Rates of Postpartum Depression?
The long-term goal of this study is to validate a simple and inexpensive intervention to reduce the incidence and impact of Postpartum Depression (PPD).
- Trial name
- NCT03793569
- Testing
- Peer discussion group
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Postpartum Depression
Effects of Esketamine on Postpartum Depression
Different concentrations of Esketamine were used after cesarean section. Through the evaluation of postoperative psychological status and analgesic effect, the optimal dosage of Esketamine to exert the effects of depression and…
- Trial name
- EEPD (NCT05229913)
- Testing
- Esketamine is not added, Esketamine 0.2mg/kg, Esketamine 0.4mg/kg
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Qinghai University
Pain
Use of Intrathecal Hydromorphone in Elective Cesarean Deliveries
The purpose of this study is to determine if intrathecal hydromorphone will relieve pain as well as intrathecal morphine after cesarean delivery, with fewer side effects.
- Trial name
- NCT01866254
- Testing
- Hydromorphone, Morphine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Grace Shih, MD
Depression, Anxiety
The Influence of Probiotic Supplementation on the Severity of Anxiety and Depressive Symptoms, as Well as the Function and Composition of Gut Microbiota, Metabolic, Inflammation, and Oxidative Stress Markers in Patients With Depression
The aim of this study is to gather empirical evidence which will enable to evaluate the impact of probiotic supplementation on the severity of anxiety and depressive symptoms, function, and composition of gut microbiota…
- Trial name
- NCT05717946
- Testing
- Probiotic composed of two bacteria strains: Lactobacillus helveticus Rosell and Bifidobacterium longum Rosell., control group
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Postpartum Depression
Preventing Postpartum Depression in Immigrant Latinas
Postpartum depression (PPD) affects 10-20% of women, with immigrant Latinas disproportionately affected. PPD prevention and treatment is limited among immigrant Latinas due to an array of structural and cultural factors…
- Trial name
- NCT05873569
- Testing
- Mothers and Babies Virtual Group Intervention
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Depression, Anxiety
Melissa Officinalis L. Supplementation for Emotional Health and Sleep Disturbance
This study is aimed to investigate if Lemon Balm Extract supplementation is beneficial for the relief of stress, depression and anxiety in healthy adults.
- Conditions
- Depression, Anxiety, Stress, Insomnia
- Trial name
- NCT05602688
- Testing
- Lemon Balm Supplement
- Where
- Pakistan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ayub Teaching Hospital
Wheel-chair Dependent Elders
Improvement and Mechanism of Wheel-chair Music Aerobic Exercise on Depression and Insomnia Among the Elderly in Long-term Care Facilities
Investigators anticipate to develop a customized WC-MAE for the improvement of insomnia and depression in wheel-chair dependent elders, and to identify related mechanisms as biomarkers for prediction and prevention of insomnia…
- Trial name
- NCT02256020
- Testing
- Original lifestyle, Wheel-chair music aerobic exercise (WC-MAE)
- Where
- Taiwan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Chang Bing Show Chwan Memorial Hospital
Anxiety, Stress
Daily Assessment of Mood and Social Media Behaviors Study
The purpose of this research study is to learn more about social media usage and its relation to emotions, biology, and mental health.
- Conditions
- Anxiety, Stress, Depression, Cortisol
- Trial name
- NCT04349423
- Testing
- Social Media Usage Manipulation
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Southern Methodist University
Asherman Syndrome
Impact of Mindfulness Based Stress Reduction on Anxiety, Depression and QOL in Women With Intrauterine Adhesion.
The purpose of this study is to determine whether mindfulness based stress reduction are effective on improve anxiety, depression and quality of life in women with intrauterine adhesion
- Trial name
- IMBSRADQWIUA (NCT02746679)
- Testing
- Mindfulness Based Stress Reduction
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Yuqing Chen
Depressive Disorder, Major
A Study to Investigate the Safety, Tolerability and Pharmacokinetics of SUVN-911 in Healthy Subjects
This is a Phase 1, conventional, double-blind, placebo-controlled, single-center clinical study comprised of 2 segments (Segment 1 and Segment 2) in which single and multiple doses of SUVN-911 or placebo will be orally…
- Trial name
- SUVN-911 (NCT03155503)
- Testing
- SUVN-911
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Suven Life Sciences Limited
Anxiety Depression
Probiotics Regulate Intestinal Health and Alleviate Anxiety
This study is a randomized, double-blind, placebo-controlled trial aimed primarily at investigating the effects of Weizmannia coagulans BC99 on alleviating anxiety and depression and the gut microbiota.
- Trial name
- NCT07353320
- Testing
- probiotics group
- Where
- China
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Postpartum Depression
Effect of Exercise and Wellness Interventions on Preventing Postpartum Depression
The purpose of this study is to examine the efficacy of the active interventions (exercise or wellness/support intervention) compared to usual care on the prevention of postpartum depression among women at risk for depression.
- Trial name
- HM2 (NCT01883479)
- Testing
- Exercise, Wellness/Support
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Community-Based Participatory Research, Adolescent Behavior
My Best Alaskan Life: A Community-Designed Intervention to Improve Youth/Young Adults' Sexual and Mental Health
This project addresses critical public health disparities among Alaskan youth and young adults by developing and evaluating "My Best Alaskan Life" (MBAL), an innovative online tool aimed at improving sexual and mental health…
- Conditions
- Community-Based Participatory Research, Adolescent Behavior, Mental Depression, Sexual Health
- Trial name
- MBAL (NCT06482242)
- Testing
- My Best Alaska Life
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Alaska Anchorage
Suicidal Ideations, Suicidal Behaviors
Technology-assisted Methods to Advance Suicide Prevention Among Youth in Colombia
This study will investigate a multi-level approach that applies technology-assisted methods to reduce suicidal thoughts and behaviors (SIB) and promote mental health among Colombian youth: (a) digital platform for youth; (b)…
- Conditions
- Suicidal Ideations, Suicidal Behaviors, Depression, Anxiety, Well-being
- Trial name
- NCT06651554
- Testing
- Digital Platform Intervention
- Where
- Colombia
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Brown University
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