Clinical trials: Depression NOS
Stress, Anxiety
Effects of High Ventilation Breathwork With Retention (HVBR) on Health
The investigators are conducting a randomised-controlled trial comparing high ventilation breathwork with retention (HVBR) to a breathwork placebo (paced breathing at 15breaths/min with brief retentions).
- Conditions
- Stress, Anxiety, Depressive Symptoms, Mental Wellbeing
- Trial name
- NCT06064474
- Testing
- High ventilation breathwork with retention (HVBR)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sussex
Depression Anxiety Disorder, Anxiety
EFCT vs. BCT for Depression and Anxiety in Married Couples
This study compares the effectiveness of Emotion-Focused Couples Therapy (EFCT) and Behavioral Couples Therapy (BCT) in reducing depression and anxiety symptoms in married couples.
- Trial name
- EFCT-BCT (NCT06892613)
- Testing
- Emotion-Focused Couples Therapy (EFCT), Behavioral Couples Therapy (BCT)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Beykoz University
Folate Deficiency, Vitamin B 12 Deficiency
Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage Girls
Folic acid and vitamin B12 play an interdependent role in key cellular processes, namely deoxyribonucleic acid synthesis, cell division, red blood cell formation, and nervous system myelination.
- Conditions
- Folate Deficiency, Vitamin B 12 Deficiency, Anemia, Megaloblastic, Cognitive Development
- Trial name
- NCT06100146
- Testing
- Folic acid and vitamin B12 fortified flour, Unfortified cereal flour
- Where
- 2 sites in Ethiopia
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- University Ghent
Bipolar Depression
Treatment Resistant Bipolar Depression
To determine if adding Escitalopram to current mood stabilizer (MS) or atypical antipsychotic (AA) will improve in rates similar to or better than adding a placebo (inactive pill)in resistant bipolar patients.
- Trial name
- NCT00272025
- Testing
- Escitalopram
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Queen's University
Major Depressive Disorder
The Role of PKC Activation in the Immune-inflammatory Mechanism of Major Depressive Depression
Major Depressive disorder (MDD) is a heterogeneous mental illness. Treated with antidepressants that act on the neurotransmitter and/or their receptors just remitted only one third of patients with MDD, Thus, to improve the…
- Trial name
- NCT04156425
- Testing
- Escitalopram+golimumab, Escitalopram+Calcium Tablet, Escitalopram
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Pain
Descriptive Study of Pain, Anxiety and Depression
The purpose of the study is to investigate pain, anxiety and depression in chronic pain patients with and without neuropathic pain compared with healthy volunteers
- Trial name
- NCT00378274
- Testing
- Observation
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Danish Pain Research Center
Bipolar Anhedonic Depression
Neurophysiological Markers in the Depressive Episode Characterized by Anhedonic Drug Resistance: Evaluation of Motor Skills and P300 Wave
Depression is currently the leading cause of disability and suicide death worldwide. Several studies, however, have shown that a significant proportion of patients do not respond to standard antidepressants, especially since…
- Trial name
- PHYDDOPA (NCT04456868)
- Testing
- Electroencephalogram, walking test, Quality of life questionnaire
- Where
- 2 sites in France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Depression, Child Development
Building Regulations in Dual Generations at KIDTHINK
Neurodevelopmental disorders (NDDs) such as attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and intellectual disability (ID) are the most frequently diagnosed disability in children, accounting…
- Conditions
- Depression, Child Development, Self-regulation
- Trial name
- NCT04893850
- Testing
- BRIDGE Therapy Program, Community Services as Usual Clinical Referral list
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Substance Abuse
Family Spirit Study
The goals of this study are to evaluate the effects of an in-home parenting education program, called Family Spirit, on parenting knowledge and skills and decreasing alcohol and substance use compared to a breast-feeding…
- Trial name
- NCT00356551
- Testing
- Family Spirit curriculum
- Where
- 5 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Post Partum Depression
Screening for Postpartum Depression Using EPDS and HAM-D in Mothers Within 72 Hours After Delivery at a Tertiary Care Center (SOS-Mamma Study)
Postpartum depression (PPD) is one of the most common complications affecting maternal mental health after childbirth, with an estimated prevalence of 10-20% in high-income countries.
- Trial name
- SOS-Mamma (NCT07025902)
- Testing
- Standardized Psychological Screening Using EPDS and HAM-D
- Where
- Italy
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Risk Reduction Behavior, Interpersonal Relations
A Community-health Worker Delivered HIV/STI Prevention Intervention for Internally Displaced Women in Leogane, Haiti
The investigators will develop, deliver and evaluate a solar powered tablet-based individual and group focused HIV/STI prevention intervention with internally displaced women in Leogane, Haiti.
- Conditions
- Risk Reduction Behavior, Interpersonal Relations, Mental Disorders
- Trial name
- FASY (NCT01492829)
- Testing
- individual and group-based, community health worker delivered
- Where
- Haiti
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Depression and Anxiety Symptoms
The Effect of Loving-Kindness Meditation on Mood and Anxiety Symptoms, Interpersonal Relationships, and Emotions: An Initial Randomized Controlled Trial With a Non-Clinical Sample of Undergraduate Women
The goal of this clinical trial was to examine the effects of Loving-Kindness Meditation (LKM) on anhedonic depressivity, interpersonal relationships (other inclusive self-concept, willingness to sacrifice, interaction quality)…
- Trial name
- NCT07611253
- Testing
- Loving-Kindness Meditation, Visualization
- Where
- Canada
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Luis Flores
Social Skills, Self-Criticism
Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking
The purpose of this randomized controlled trial is to evaluate an intervention, Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS).
- Conditions
- Social Skills, Self-Criticism, Post-traumatic Stress Disorder, Depression
- Trial name
- NCT03488927
- Testing
- Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS)
- Where
- United States
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- University of New Hampshire
Posttraumatic Stress Disorder, Depression
The Pitt Center for Emergency Responder Wellness
Emergency responders protect the public despite occupational hazards that threaten their mental health. The Pitt Center for Emergency Responder Wellness will be a clinical innovation hub that: 1) delivers accessible interventions…
- Conditions
- Posttraumatic Stress Disorder, Depression, Anxiety, Alcohol Use Disorder
- Trial name
- NCT05357586
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cystic Fibrosis
Treatment of Anxiety/Depression and Pain Through Relaxation Yoga for Patient With Cystic Fibrosis (CF)
The investigators research question is whether or not yoga effectively alleviates symptoms of pain, sleep disturbance, anxiety and depression in children with cystic fibrosis.
- Trial name
- NCT01180842
- Testing
- Yoga treatment program
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Cognition Disorders, Depression
Well-Being in Medical Residents in the HIBA
It is necessary and important to design tools to evaluate a central aspect of medical residents formation. The research group has been working with resident well-being since a few years in order to improve the global quality of…
- Conditions
- Cognition Disorders, Depression, Anxiety, Shift-Work Sleep Disorder
- Trial name
- NCT03087435
- Testing
- Well-Being questionnaire
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Fibromyalgia, Coronavirus Disease 2019 Pandemic
Anxiety, Depression, and Quality of Life in Patients With Fibromyalgia During the Coronavirus Disease 2019 Pandemic
Fibromyalgia patients and controls living in the same household will be evaluated for levels of resilience, covid-19 related anxiety, coronavirus disease 2019 related obsession, quality of life and pain and comparisons and…
- Trial name
- NCT05410808
- Testing
- Questionnaires and physical examination, Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ege University
Depression, Anxiety, Adolescent Behavior
A Trauma-Informed Approach for Positive Youth Development for Montana Students
Given the prevalence of suicide and mental health issues in rural Montana, this project is intended to help mitigate stressors that may contribute to poor behavioral and mental health in high school-aged children.
- Conditions
- Depression, Anxiety, Adolescent Behavior, Stress
- Trial name
- NCT04234425
- Testing
- Trauma-Informed Yoga
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Montana State University
Alcohol; Use, Problem, Stress
A Behavioral Activation Intervention Administered in a College Freshman Orientation Course
The transition from high school to college is a developmentally sensitive period that is high risk for escalations in alcohol use.
- Conditions
- Alcohol; Use, Problem, Stress, Binge Eating, Depression
- Trial name
- NCT04038190
- Testing
- behavioral activation
- Where
- United States
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Major Depressive Disorder
Identifying Biological Markers for Severe Depression
The primary objective of this study is to investigate the biological components of major depression. The investigators are particularity interested in genetic variation and how it contributes to cortisol (because cortisol is…
- Trial name
- NCT01831882
- Where
- 3 sites in United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Stanford University
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