Clinical trials: Depression NOS
Postpartum Depressive Mood, Postpartum Sexual Function
Oral Contraceptive Ethinyl Estradiol Dose Effect on Postpartum Depression and Sexual Functioning Scales
This is a prospective, randomized, controlled cohort study. This study will look at the effect of Ethinyl Estradiol 35mcg/Norethindrone 1mg and Ethinyl Estradiol 20 mcg/Norethindrone 1mg on postpartum depressive symptoms and…
- Trial name
- NCT02210702
- Testing
- Ethinyl Estradiol 35mcg/Norethindrone 1mg, Ethinyl Estradiol 20mcg/Norethindrone 1mg
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- The Jones Institute
Chronic Periodontitis, Depression
Comparing Inflammatory Markers in Patients With and Without Depression With Chronic Periodontitis
This study will evaluate whether use of antidepressants can reduce gingival inflammation in patients with periodontal (gum) disease.
- Trial name
- NCT03553095
- Testing
- Periodontal Surgery
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Depression, Generalized Anxiety
The Mental Health Status of the General Population During the COVID-19 Pandemic and Its Association With Adherence to Government-initiated Non-pharmacological Epidemiological Interventions (NPI's)
This study seeks to investigate the levels of common psychopathology symptoms (i.e., depression and generalized anxiety) in a general population during the strict social distancing government-initiated non-pharmacological…
- Conditions
- Depression, Generalized Anxiety, Adherence to Non-pharmacological Epidemiological Interventions (NPIs)
- Trial name
- NCT04356365
- Testing
- Cross-sectional study investigating the association of NPIs with mental health
- Where
- Norway
- Volunteers
- 10,084 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Depressive Disorder, Major, Major Depressive Disorder (MDD)
Study Of GW679769 In Major Depressive Disorder
This is a placebo-controlled, fixed dose study that will evaluate the efficacy and safety of GW679769 in subjects with major depressive disorder.
- Trial name
- NCT00102492
- Testing
- GW679769
- Where
- 31 sites in United States, Canada
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Post Partum Depression
Risk of Maternal Depression From 1 Year to 4 Years Postpartum in Yvelines
This observational study aims to estimate the prevalence of women from 1 to 4 years postpartum in Yvelines, who are suspected to suffer from postpartum depression, using the Edinburg Post natal Depression Scale (EPDS) and the…
- Trial name
- DeTaPoP (NCT06042972)
- Testing
- Questionnaire including Edinburgh postnatal depression scale, Patient Health Questionnaire 2 and background variables
- Where
- France
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Centre Médical Porte Verte
Depressive Symptoms, Anxiety Symptoms
Attachment and Biobehavioral Catch-up for Depression
The overarching goal is to pilot the Attachment and Biobehavioral Catch-up (ABC) intervention for mothers with heightened depressive symptom and their children with heightened internalizing symptoms.
- Trial name
- ABC (NCT04050202)
- Testing
- Attachment and Biobehavioral Catch-up (ABC) Intervention
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Major Depression With Comorbid Anxiety Symptoms
A Double Blind, Randomized Placebo Controlled Study of the Efficacy, Safety and of Quetiapine Fumarate (Seroquel®) as Potentiation SSRI's, and SNRI's Treatment in Major Depression With Anxiety
Major depression occurs with generalized anxiety disorder and panic disorder in up to 60% of psychiatric and primary care patients.(1) An estimated 85% of adults with depression experience significant symptoms of anxiety and 58%…
- Trial name
- NCT00229645
- Testing
- Quetiapine Fumarate (Seroquel®)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr Alexander McIntyre Inc.
Depression, Anxiety
Perinatal Mental Health Study (PMHS) India
The purpose of this observational study is to improve understanding of mental disorders among perinatal women in India.
- Conditions
- Depression, Anxiety, Suicidal Ideation, Somatization
- Trial name
- PMHS (NCT05485701)
- Testing
- Screening tools for common mental disorders
- Where
- 2 sites in India
- Volunteers
- 2,332 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health
Ambient air temperatures in Asian, Latin American, African, and Pacific climate hotspots have broken record highs in 2024, driven by man-made climate change. Solutions are needed to reduce heat exposure in communities.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06579950)
- Testing
- Cool roof
- Where
- 5 sites in Burkina Faso, Fiji and 3 more
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Brain Fog, Cognitive Impairment
Cognitive Task-Based Walking Effects on Cognition, Mood, Sleep, and Quality of Life in Older Adults With Brain Fog
This randomized controlled trial aims to investigate the effects of cognitive task-based walking exercise on cognitive function, depressive symptoms, sleep quality, and quality of life in older adults experiencing brain fog.
- Conditions
- Brain Fog, Cognitive Impairment, Geriatric Population
- Trial name
- NCT07396779
- Testing
- Cognitive Task-Based Walking Exercise, Walking-Only Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medipol University
Bipolar Disorder, Bipolar I Depression
Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder
Lithium is highly effective in the treatment of bipolar disorder. This study aims to investigate, for the first time, the impact of lithium monotherapy on the structural and functional connectivity of the brain using MRI imaging.
- Conditions
- Bipolar Disorder, Bipolar I Depression, Bipolar II Depression, Bipolar Depression
- Trial name
- NCT03336918
- Testing
- Lithium
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Contraception, Mood Change
Stress Hormones and IUDs
Determine what kind of side effects women experience in the first year after they start using an intrauterine device.
- Trial name
- NCT03499379
- Testing
- Mirena, Paraguard
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Major Depressive Disorder
Gut Feeling: Understanding the Mechanisms Underlying the Antidepressant Properties of Probiotics
Previous research has suggested that probiotics can improve depressive symptoms in patients with Major Depressive Disorder (MDD), particularly when used in addition to antidepressants.
- Trial name
- PROMEX (NCT03893162)
- Testing
- Multi-strain probiotic
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King's College London
Perinatal Depression, Post Partum Depression
Characterizing the Neural Substrates of Irritability in Women: an Experimental Neuroendocrine Model
The proposed study involves experimentally manipulating reproductive hormones in nonpregnant, euthymic women to create a scaled down version of the changes that occur during pregnancy and the postpartum period.
- Conditions
- Perinatal Depression, Post Partum Depression, Depression, Postpartum, Depression
- Trial name
- NCT04051320
- Testing
- Leuprolide Acetate 3.75 MG/ML, Estradiol 2 Mg tablet, Micronized progesterone
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Intervention, Control
A Sleep Intervention for Cancer Patients and Their Caregivers
The purpose of the study is to design and test a dyadic sleep intervention for patients diagnosed with cancer and their intimate partner.
- Trial name
- NCT04969146
- Testing
- Dyadic Intervention, Patient Only Intervention
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Schizophrenia, Autism Spectrum Disorder
Cerebellar Stimulation and Cognitive Control
The purpose of this study is to examine whether cerebellar stimulation can be used to improve cognitive deficits and mood in patients with schizophrenia, autism, bipolar disorder, Parkinson's disease, and major depression.
- Conditions
- Schizophrenia, Autism Spectrum Disorder, Bipolar Disorder, Depression
- Trial name
- NCT03217110
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Krystal Parker, PhD
Depression, Anxiety
The 28 Day Challenge
The purpose of this study is to determine how a 28 Day Challenge influences mental health and well-being. This is a blinded study. Participants both with and without depression and anxiety, will be included.
- Conditions
- Depression, Anxiety, Stress, Hope
- Trial name
- NCT03936946
- Testing
- Audio Content 1, Audio Content 2
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Burnout, Professional, Depression
Does a Phone-based Meditation Application Improve Mental Wellness in Emergency Medicine Personnel?
Emergency medicine is notorious for its high rate of burnout and mental health issues. The emergency department (ED) is a high paced work environment dealing with life and death issues.
- Conditions
- Burnout, Professional, Depression, Anxiety, Stress
- Trial name
- NCT03811990
- Testing
- Cleveland Clinic Stress Free Now Meditations For Healers
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Obsessive Compulsive Disorder, Major Depressive Disorder
Integrating Pharmacogenomic Testing Into a Child Psychiatry Clinic
The purpose of this study is to examine the feasibility, acceptability, and utility of pharmacogenomic (PGX) testing (specifically for the cytochrome P450 2D6 and 2C19 genes) prior to initiating treatment with an antidepressant…
- Conditions
- Obsessive Compulsive Disorder, Major Depressive Disorder, Anxiety
- Trial name
- PGX (NCT02855580)
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Florida
Multiple Sclerosis, Kinesiophobia
Evaluation of the Presence and Effects of Kinesiophobia in Multiple Sclerosis
The aim of this study was to evaluate the presence of kinesiophobia in multiple sclerosis and to investigate the effect of kinesiophobia on physical activity, functional status, quality of life and depression.
- Trial name
- NCT06167447
- Testing
- questionnaire and examination
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gazi University