Clinical trials: Depression Symptom
Chronic Pain, Cancer
Cancer Chronic Pain Predicted by Emotional and Cognitive Status
The aim of this study is to investigate the predictive dimension of cognitive-emotional status of cancer patients on the chronic pain development 6 months after different cancer treatment protocol (surgery, chemotherapy…
- Trial name
- CanoPEe (NCT02777697)
- Testing
- chronic pain
- Where
- France
- Volunteers
- 89 people
- Sponsor
- University Hospital, Clermont-Ferrand
Depression, Anxiety
Feasibility and Acceptability of W-GenZD vs CBT-light Teletherapy for Adolescents Seeking Mental Health Services
The primary aim of this study is to determine the feasibility and acceptability of the W-GenZD mobile application among a group of adolescents and who have screened and triaged into low-intensity treatment within the Children's…
- Trial name
- NCT05372913
- Testing
- Woebot for Adolescents (W-GenZD) Mobile Application, CBT-Lite Teletherapy Group
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Woebot Health
Depressive Disorder, Pregnancy
EnBrace HR for Depression Treatment and Prevention in Women Trying to Conceive and Early Pregnancy
The purpose of this study is to assess the effectiveness of the EnBrace HR prenatal supplement in preventing depression in women with a history of depression who have decided to stop taking antidepressants during their pregnancy…
- Trial name
- NCT02676882
- Testing
- EnBrace HR
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Bipolar Depression
Lurasidone - A 24-week Extension Study of Patients With Bipolar I Depression
This clinical study is designed to test the hypothesis that lurasidone is effective, tolerable, and safe for the treatment of patients with bipolar I depression
- Trial name
- NCT00868959
- Testing
- lurasidone
- Where
- 151 sites in United States, Canada and 13 more
- Volunteers
- 817 people
- Sponsor
- Sumitomo Pharma America, Inc.
Mild Cognitive Impairment (MCI), Dementia Alzheimer Type
Global Collaborative Research on Establishing a Korean Cognitive Aging Cohort
The goal of this observational study is to learn how daily emotional stress affects cognitive function and inflammation in community-dwelling older adults aged 60 and older in Seoul, Republic of Korea.
- Conditions
- Mild Cognitive Impairment (MCI), Dementia Alzheimer Type, Chronic Pain, Depression - Major Depressive Disorder
- Trial name
- KoCoA cohort (NCT07485387)
- Where
- South Korea
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Korea University
Depressive Symptoms, Depression
Evaluation of a Mobile Therapy for Elevated Depressive Symptoms
The purpose of this research study is to evaluate a mobile application (app) for depression treatment. Participants will be randomly assigned to either receive the mobile app, "Moodivate", or not.
- Trial name
- NCT04463914
- Testing
- Behavioral Activation Therapy app, Behavioral Activation Therapy app + EHR, Treatment as Usual
- Where
- United States
- Volunteers
- 649 people
- Sponsor
- Medical University of South Carolina
Depression, Aortic Stenosis
Depression and Major Adverse Events in Older Patients Who Undergo a Transcatheter Aortic Valve Implantation
Depression, screened using the Geriatric Depression Scale (GDS) Short Form, has recently been found to be associated with a 3-fold increase in 1-year mortality after aortic valve replacement (AVR) in patients aged 70 or older.
- Trial name
- TAVIDEP (NCT03995914)
- Sponsor
- University Hospital, Montpellier
Hunger, Depression
Carbohydrate Rich Drink Reduces Pre-endoscopic Discomfort for Patients Going for Elective Endoscopic Procedures
The study is a randomised controlled trial that aims to evaluate whether carbohydrate loading pre-endoscopy can improve patients' overall satisfaction and is not associated with negative impact on endoscopic quality or increased…
- Conditions
- Hunger, Depression, Anxiety, Vomiting
- Trial name
- NCT05342116
- Testing
- Nestle Preload, Water
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Treatment Resistant Depression
Working Mechanisms and Effectiveness of IV Ketamine-assisted Psychotherapy on Depression in TRD Clients
Ketamine-Assisted Psychotherapy (KAP) is an innovative treatment that combines intravenous ketamine with psychotherapy in a carefully monitored clinical setting.
- Trial name
- NCT07706478
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- Senz
Moderate Depression, Major Depressive Disorder
The Dosage Effect of pBFS Guided rTMS Treatment for MDD
The investigators aim to find the optimal dosage of the pBFS-guided rTMS treatment for patients with moderate to severe depression.
- Conditions
- Moderate Depression, Major Depressive Disorder, Severe Depression
- Trial name
- NCT05842278
- Testing
- 4 session rTMS, 6 session rTMS, 8 session rTMS
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Changping Laboratory
Depression, Suicidal Ideation
Social Connections and Late Life Suicide
With the long-term goal of improving interventions for late-life suicide, the purpose of this study is to examine whether a mechanism by which behavioral interventions reduce risk for late-life suicide is by increasing social…
- Trial name
- NCT02188485
- Testing
- ENGAGE
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Rochester
Substance-Related Disorders, Mood Disorders
Behavioral Activation for Heroin Use in China: A Randomized Controlled Trial
This was a single-site two-arm parallel-group trial conducted in a Methadone Maintenance Treatment (MMT) Clinic that provides medication service for 254 heroin users in Wuhan, China.
- Conditions
- Substance-Related Disorders, Mood Disorders, Behavioral Activation Treatment, Mental Disorders
- Trial name
- NCT03705143
- Testing
- Treatment as usual, Chinese translated LETS ACT
- Where
- China
- Volunteers
- 90 people
- Sponsor
- University of North Carolina, Chapel Hill
HIV, Depressive Symptoms
Relaxation, Depressive Symptoms, Quality of Life in People Living With HIV: a Pilot Study
Progressive muscle relaxation (PMR) and autogenic training (AT) are effective relaxation techniques to reduce depressive symptoms.
- Trial name
- NCT01901016
- Testing
- Jacobson progressive muscular relaxation, Schultz's autogenic training
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Université de Montréal
Depressive Disorder, Major
A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy
The purpose of this study is to assess the efficacy of Seltorexant compared with placebo as adjunctive therapy to an antidepressant in improving depressive symptoms in participants with major depressive disorder with insomnia…
- Trial name
- NCT04532749
- Testing
- Seltorexant
- Where
- 80 sites in United States, Argentina and 8 more
- Volunteers
- 212 people
- Sponsor
- Janssen Research & Development, LLC
Major Depressive Disorder (MDD)
Magnesium Supplementation With Fluoxetine for Cognitive Function in Depression
The goal of this clinical trial is to evaluate whether magnesium supplementation can improve cognitive function in patients with depression receiving fluoxetine therapy.
- Trial name
- MAG-DEP (NCT07521358)
- Testing
- Fluoxetine (drug), Magnesium
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Hasanuddin University
Cognitive/Functional Effects, Depression
Physical and Mental Assessment of Older Patients With Newly Diagnosed Acute Myeloid Leukemia
RATIONALE: Learning about physical ability and mental function over time in older patients with acute myeloid leukemia may help doctors learn about the long-term effects of treatment and plan the best treatment.
- Conditions
- Cognitive/Functional Effects, Depression, Leukemia
- Trial name
- NCT00499785
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Wake Forest University Health Sciences
Chronic Obstructive Pulmonary Disease, Depression
Effectiveness and Cost-effectiveness of Digital Psychological Intervention (EmoEase) in Chinese COPD Patients
Background Mental health issues are common and often overlooked in COPD patients. Digital psychological interventions might help, but their effectiveness in Chinese COPD patients hasn't been studied.
- Conditions
- Chronic Obstructive Pulmonary Disease, Depression, Anxiety
- Trial name
- NCT06026709
- Testing
- EmoEase
- Volunteers
- 1,200 people
- Sponsor
- Peking Union Medical College
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
Clinical Trial to Assess the Improvement of Fatigue, Sleep Problems, Anxiety / Depression, Neurovegetatives Alterations and Quality of Life After the Administration of ImmunoVita® in Chronic Fatigue Syndrome Patients
Chronic Fatigue Syndrome, also known as Myalgic Encephalomyelitis (CFS / MS) is a medical entity characterized mainly by debilitating and prolonged fatigue lasting more than 6 months, post-exertion fatigue (physical and / or…
- Trial name
- NCT04301609
- Testing
- Active
- Where
- Spain
- Volunteers
- 67 people
- Sponsor
- Vitae Health Innovation
Mental Health
Educational Intervention for Optimizing Adolescent Mental Health Screening and Treatment in Pediatric Residency
The purpose of this study is: 1) to assess pediatric resident knowledge of adolescent mental health; 2) to assess pediatric resident comfort level for screening, assessing, and treating mental health disorders in adolescents…
- Trial name
- NCT00768352
- Testing
- Educational intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Emotion Regulation, Stress
Evaluation of a Transdiagnostic Mobile App Intervention Among University Students
This study is a two-armed randomized controlled trial (RCT) aimed at evaluating the effectiveness and adoption of a transdiagnostic mobile app intervention that focuses is on enhancing adaptive emotional regulation (ER) skills…
- Conditions
- Emotion Regulation, Stress, Resilience, Depressive Symptoms
- Trial name
- NCT06224647
- Testing
- Mobile Transdiagnostic Emotion Regulation Intervention
- Where
- Netherlands
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Erasmus University Rotterdam
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.