Clinical trials: Depression Symptom
Depressive Disorder, Major Depressive Disorder
Study Evaluating Desvenlafaxine Succinate Sustained-Release Tablets (DVS SR) In The Treatment Of Child and Adolescent Outpatients With Major Depressive Disorder
The primary purpose of this study is to evaluate the long-term safety and tolerability of Desvenlafaxine Succinate Sustained-Release (DVS SR) in child and adolescent outpatients with major depressive disorder.
- Trial name
- NCT00669110
- Testing
- Desvenlafaxine Succinate Sustained-Release Tablets (DVS SR)
- Where
- 9 sites in United States
- Volunteers
- 40 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Post-traumatic Stress Disorder (PTSD), Acute Stress Disorder
EMDR Flash Group Protocol for Earthquake Survivors
This pilot randomized controlled trial evaluated the preliminary effects of the online EMDR Flash Group Protocol among adults affected by the 2023 Kahramanmaraş earthquakes in Türkiye.
- Conditions
- Post-traumatic Stress Disorder (PTSD), Acute Stress Disorder, Anxiety, Depression
- Trial name
- FlashGP-EQ (NCT07672613)
- Testing
- EMDR Flash Group Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Istanbul Galata University
Depressive Symptoms, Mental Health Wellness 1
Mindfulness and Intercare Based Intervention for Medicine Students (MIIM)
The effects of Coronavirus Disease (COVID-19) pandemic on health, economy and social network has an impact on mental health, specially students.
- Conditions
- Depressive Symptoms, Mental Health Wellness 1, Anxiety
- Trial name
- MIIM (NCT05011955)
- Testing
- Mindfulness, compassion and intercare based Intervention, Psychoeducational based intervention, General curricular intervention
- Where
- Chile
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University Diego Portales
Depression / Major Depressive Disorder
Adjunctive Probiotic Therapy in Major Depressive Disorder (ProMOOD)
A double-blind, randomized controlled trial (RCT) aimed at evaluating the efficacy of probiotic supplementation in patients undergoing concurrent antidepressant therapy.
- Trial name
- ProMOOD (NCT07786285)
- Testing
- OMNi-BiOTiC® STRESS Repair
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- University Maribor
Late-life Depression, Major Depressive Disorder
Cognitive Behavioural Therapy for the Treatment of Late Life Depression
This study addresses the unmet medical problem of insufficient treatment of late life depression (LLD). Compared with depression in early adulthood, treatment options of LLD are limited.
- Conditions
- Late-life Depression, Major Depressive Disorder, Major Depressive Episode, Major Depressive Disorder, Recurrent
- Trial name
- CBTlate (NCT03735576)
- Testing
- Psychotherapy, Questionnaires, Magnetic Resonance Imaging
- Where
- 7 sites in Germany
- Volunteers
- 250 people
- Sponsor
- University of Cologne
Mastodynia
Evaluation of Sleep Quality, Nutrition, Anxiety and Depression in Mastalgia
The aim of this study is to investigate the sleep quality, anxiety and depression levels in women with mastalgia using internationally validated scales.
- Trial name
- NCT04690218
- Testing
- Hospital anxiety and depression scale, Pittsburgh Sleep Quality Index, Nutritional Status Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Depression
Nature-based Treatment Group for Depression
This multi-centre research investigates the effects of nature-based treatment group on participants diagnosed with depression. In total, 147 persons participated in the study in various locations in Finland.
- Trial name
- NCT04897685
- Testing
- Flow with Nature
- Where
- 3 sites in Finland
- Volunteers
- 147 people
- Sponsor
- JAMK University Of Applied Sciences
Depressive Disorder, Musculoskeletal Pain
Multicomponent Program for the Integrated Management of Chronic Pain and Depression in Primary Care
This study evaluates whether the implementation of an integrated clinical program for chronic musculoskeletal pain and depression behave better clinical outcomes than the usual approach in primary care
- Conditions
- Depressive Disorder, Musculoskeletal Pain, Chronic Pain
- Trial name
- DROP (NCT02605278)
- Testing
- Clinical program for pain and depression, Control
- Where
- Spain
- Volunteers
- 330 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Depressive Symptoms, Perinatal Loss
e-Perinatal Butterfly: An Embedded Study for Parents Experiencing Perinatal Loss
This study is part of the e-Perinatal project and is embedded within the parent e-Perinatal cluster randomized controlled trial (NCT07613008). No additional randomization is performed for this embedded study.
- Conditions
- Depressive Symptoms, Perinatal Loss, Perinatal Grief, Anxiety Symptoms
- Trial name
- e-Butterfly (NCT07898176)
- Testing
- e-Perinatal Butterfly, Standard routine maternal care
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Seville
Depression, Self Harm
Integrated Mental Healthcare Plan for Management of Depression and Self-harm in Pakistan
Aims: 1. To describe the process of developing a feasible district mental healthcare plan (MHCP) for depression, self-harm and suicide prevention, and 2.
- Trial name
- PRIME-PK (NCT05767840)
- Testing
- psychological interventions
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Pakistan Institute of Living and Learning
Infertility, Emotional Disorder
Online Prevention of Emotional Disorders in Women Undergoing Fertility Treatments
The main aim of this pilot study is to study the clinical utility and acceptability of a transdiagnostic psychological intervention, the Unified Protocol, delivered in online format to prevent the onset of emotional disorders in…
- Conditions
- Infertility, Emotional Disorder, Anxiety Depression
- Trial name
- RE-FER moodle (NCT06420674)
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Jorge Javier Osma López
Depression
Metacognitive Training Program With Depression
The participants of this study have been diagnosed with mild to moderate depression with no evidence of suicidal actions prior to recruitment.
- Trial name
- DMKT (NCT02415426)
- Testing
- Metacognitive Training Program during mild to moderate depression
- Where
- Switzerland
- Volunteers
- 2 people
- Sponsor
- Psychiatric University Hospital, Zurich
Major Depressive Disorder
MemFlex to Prevent Depressive Relapse
A wealth of research has demonstrated that they way in which the investigators recall our personal, autobiographical memories is influential in the course of depression.
- Trial name
- NCT02614326
- Testing
- Autobiographical Memory Flexibility (MemFlex) training, Psychoeducation
- Where
- 2 sites in United Kingdom
- Volunteers
- 70 people
- Sponsor
- Medical Research Council Cognition and Brain Sciences Unit
Care Burden, Anxiety
Group Music Therapy Intervention With Informal Carers of Elderly Dependents
To evaluate the effects of a group music therapy intervention with informal caregivers of elderly people on clinical psychological symptoms, taking into account variables such as caregiver burden, anxiety and depression.
- Conditions
- Care Burden, Anxiety, Depression, Coping Strategies
- Trial name
- MUSIC CARES (NCT06028815)
- Testing
- Group music therapy
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- University of Deusto
Heart Failure, Depressive Symptoms
Effects of a Rehabilitation Program on Immune Activation and Mood in Heart Failure Patients
The aim of this descriptive study is to examine potential changes regarding inflammatory cytokine levels, depressive symptoms and quality of life over the course of the 4-week inpatient rehabilitation program which includes a…
- Trial name
- NCT02358525
- Testing
- multi-modality rehabilitation program for heart failure
- Where
- 2 sites in Austria
- Volunteers
- 16 people
- Sponsor
- Ludwig-Boltzmann Institut fuer Rheumatologie, Balneologie und Rehabilitation
PTSD, Post Traumatic Stress Disorder, Major Depressive Disorder
Ketamine Treatment for PTSD and MDD in TBI
The goal of this clinical trial is to examine the use of sedative ketamine to treat depression and post-traumatic stress disorder (PTSD) in Veterans with mild to moderate traumatic brain injury (TBI).
- Conditions
- PTSD, Post Traumatic Stress Disorder, Major Depressive Disorder, Traumatic Brain Injury
- Trial name
- NCT06228391
- Testing
- IV ketamine, Midazolam
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Depressive Disorder
The Effect of Minocycline on Relapse After Successful Intravenous Ketamine/Minocycline-induced Symptoms Response in Subjects With Depression
The purpose of this study is to assess whether the antidepressant effect from intravenous (IV) ketamine treatment can be maintained by minocycline compared to placebo after IV ketamine treatment is stopped.
- Trial name
- NCT01809340
- Testing
- Minocycline, Ketamine
- Where
- 12 sites in Belgium, France and 2 more
- Volunteers
- 29 people
- Sponsor
- Janssen Research & Development, LLC
Depression Mild, Depression Moderate
An Online Intervention Targeting Depression and Low Reward Sensitivity
This study aims to evaluate and compare the effectiveness of different online interventions targeting reward sensitivity and depressive symptoms.
- Trial name
- NCT05402150
- Testing
- Behavioral Activation, Mindulness and Gratitude, Combination of Behavioral Activation and Mindfulness and Gratitude
- Where
- Germany
- Volunteers
- 224 people
- Sponsor
- Philipps University Marburg
Older Age; Depression
Online MBCT vs HEP for Depressive Symptoms in Older Adults: RCT
In Canada, depression affects more than 300,000 adults over the age of 60, which costs the healthcare system an estimated $5 billion each year.
- Trial name
- OMH-D RCT (NCT06189118)
- Testing
- Online Mindfulness Based Cognitive Therapy or Health Education Program
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Lady Davis Institute
Depression, Anxiety
Bridging the Gap to Improve Mental Health Treatment Utilization
Bridging the Gap aims to improve access to effective mental health treatment in a primary care setting through utilization of single session growth mindset interventions for parents and for youths.
- Conditions
- Depression, Anxiety, Adolescent Behavior, Suicidal Ideation
- Trial name
- NCT04558489
- Testing
- IPR + GMI
- Where
- United States
- Sponsor
- University of Pittsburgh
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