Clinical trials: Depression Symptom
Asymptomatic Condition, Neck Pain
Accessory Movements and Associated Factors During Active Cervical Range of Motion
This project aims to quantify accessory movements that occur during cervical range of motion (ROM) assessment in young adults and to examine their relationship with functional and psychological factors.
- Trial name
- NCT07267507
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Atılım University
Depression, Depressive Disorder
Remote Coaching for Supporting the Implementation of Depression Care in Primary Care in Rural India
This cluster-randomized hybrid type-II implementation superiority trial will include 14 rural primary care facilities in Madhya Pradesh, which will implement a collaborative depression care packaged based on the WHO mhGAP…
- Conditions
- Depression, Depressive Disorder, Psychological, Noncommunicable Diseases
- Trial name
- ESSENCE-IT (NCT05264792)
- Testing
- Enhanced Implementation Support, Routine Implementation Support
- Where
- India
- Volunteers
- 14 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Depression
Extension Study of the Safety and Efficacy of Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder
The primary objective of this study is to evaluate the safety and tolerability of long term (6 months) armodafinil treatment as adjunctive therapy to mood-stabilizing medications in adults with bipolar I disorder.
- Trial name
- NCT01121536
- Testing
- Armodafinil
- Where
- 158 sites in United States, Argentina and 15 more
- Volunteers
- 867 people
- Sponsor
- Cephalon
Depression
Childhood Adversity, Genetic Polymorphisms and Stress in First Onset Major Depression
The Blue Sky Project, a 5-year study funded by the Canadian Institutes of Health Research, seeks to examine how genetics and early life experiences work together to cause a person's very first onset of depression by increasing…
- Trial name
- NCT00517764
- Testing
- escitalopram
- Where
- 2 sites in Canada
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Chronic Heart Failure
Preliminary Study Examining Heart Failure Patients Responses to Depression Education
Purpose of the Study: The significant impact of depression on the poor prognosis and functional restrain, recognition and successful treatment of depression in patients with Chronic Heart Failure (CHF) may result in improvement…
- Trial name
- NCT01794598
- Testing
- Receiving educational material of depression care
- Volunteers
- 270 people
- Sponsor
- Duke University
Anhedonia, Major Depressive Disorder (MDD)
Efficacy of kTMP, a Novel Non-invasive Brain Stimulation Method, for the Treatment of Anhedonia
The goal of this proposal is to provide a first assessment of the efficacy of our innovative non-invasive brain stimulation system, kTMP, in the treatment of anhedonia in MDD.
- Trial name
- kTMP Anhedonia (NCT07032428)
- Testing
- A new non-invasive brain stimulation tool
- Volunteers
- 104 people
- Sponsor
- Magnetic Tides
Anxiety, Depression
Online Multi-component Psychological Intervention for Healthcare Workers During COVID-19 Pandemic
The objective of this study is to carry out a randomized clinical trial with healthcare workers in Mexico through a web platform.
- Conditions
- Anxiety, Depression, Sleep Disturbance, Quality of Life
- Trial name
- NCT04890665
- Testing
- Online psychological intervention for healthcare workers
- Where
- 3 sites in Mexico
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidad Internacional de Valencia
Sjogren's Syndrome, Fatigue
Fatigue in Primary Sjögren's Syndrome
Fatigue is a common clinical finding in Primary Sjögren's syndrome (PSS). In PSS, there is not enough data about the conditions in which fatigue develops and which clinical conditions the disease is associated with.
- Conditions
- Sjogren's Syndrome, Fatigue, Pain Syndrome, Depression
- Trial name
- NCT04802577
- Testing
- FACT-F questionnaire, Beck Depression Inventory, Beck Anxiety Inventory
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Neurodegenerative Disease, Dementia
Cognition and Affective Research in China
This is a prospective cohort study of patients with cognitive impairment mood disorders and behavioral disorders. Comprehensive baseline and longitudinal follow-up assessments include clinical and epidemiological data, cognitive…
- Conditions
- Neurodegenerative Disease, Dementia, Alzheimer's Disease, Parkinson's Disease
- Trial name
- CARE (NCT07833267)
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Depression, Bipolar Disorder
Brain Imaging in Depression
The purpose of this study is to use brain imaging technology to examine the role of certain brain receptors and the nervous system chemical acetylcholine in major depression.
- Trial name
- NCT00050700
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Obesity
Binge Eating, Depression and Anxiety Outcomes After Sleeve Gastrectomy Versus Gastric Bypass: A Cohort Study
The goal of this clinical trial is to learn if the type of weight-loss surgery (sleeve gastrectomy or gastric bypass) affects binge eating, depression, and anxiety in adults with severe obesity.
- Trial name
- NCT07600411
- Testing
- Laparoscopic Sleeve Gastrectomy, Gastric Bypass
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Environmental Exposure, Winter Depression
Health Consequences of Wintering in the French Southern and Antarctic Territories
Polar stays expose people to extreme climate, isolation and confinement. The combination of these factors induces psychological disorders, sleep disorders, immune and endocrine disturbances, and deficiencies.
- Conditions
- Environmental Exposure, Winter Depression, Endocrine System Diseases, Sleep Disorder
- Trial name
- MediTAAF (NCT04768621)
- Testing
- Questionary
- Where
- Reunion
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Lung Transplant; Pain
Impact of a Multidisciplinary Protocol of Respiratory Kinesitherapy and Active Music Therapy on Anxiety, Depression and Pain in Lung Transplant Patients
Transplantation remains the last resort to prolong life when the patient reaches the stage of terminal respiratory failure. Lung transplantation improves survival and quality of life compared to medical treatment, at acceptable…
- Trial name
- PPKRMA (NCT05219292)
- Testing
- Active music therapy, Questionnaires
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Hospices Civils de Lyon
Job Related Stress
Three Good Things 2020: a Brief Text-based Wellness Intervention
This trial will be open to all Michigan Medicine Department of Family Medicine faculty, resident, or staff. The intervention will consist of asking participants the "3 Good Things" based on positive psychology theory.
- Trial name
- NCT04676698
- Testing
- Three Good Things, Wait list control arm and then Three Good Things
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- University of Michigan
Depression, Bipolar Disorder
Minocycline and Celecoxib as Adjunctive Treatments of Bipolar Depression
Bipolar disorder is a leading cause of disability worldwide. A high proportion of patients with bipolar disorder experience persistent depressive symptoms that do not respond to standard drug treatments.
- Conditions
- Depression, Bipolar Disorder, Bipolar Depression, Mood Disorders
- Trial name
- NCT02703363
- Testing
- Minocycline, Celecoxib
- Where
- 4 sites in Pakistan
- Volunteers
- 265 people
- Sponsor
- Pakistan Institute of Living and Learning
Depressive Disorder, Depression
Adaptive Design Study of NEST sTMS in Subjects With Major Depressive Disorder
This is a double-blind, sham controlled, multi-center study to confirm the safety and efficacy of synchronized transcranial magnetic stimulation (sTMS) for the treatment of patients currently experiencing an episode of depression…
- Conditions
- Depressive Disorder, Depression, Depressive Disorder, Major, Depressive Episode
- Trial name
- NCT03288714
- Testing
- Synchronized Transcranial Magnetic Stimulation (sTMS)
- Where
- 14 sites in United States
- Volunteers
- 121 people
- Sponsor
- Wave Neuroscience
Major Depressive Disorder
A Study of the Cost Effectiveness of Generalist Care Managers for Depression Treatment in Medicaid Recipients
This project will enable the investigators to conduct a randomized clinical trial to demonstrate the value of generalist care managers in the treatment of depression in Medicaid patients seen in primary health care practices.
- Trial name
- NCT00373477
- Testing
- Generalist Care Manager vs Usual Care
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of North Carolina
Depression
Predicting Effectiveness of Light Treatment for Winter Seasonal Affective Disorder
This study will evaluate a possible tool for predicting future effectiveness of bright light in treating seasonal affective disorder, winter subtype, and will examine secondary effects of bright light on cardiovascular risk…
- Trial name
- NCT00742365
- Testing
- Bright light
- Volunteers
- 41 people
- Sponsor
- University of Maryland, Baltimore
Depression, Anxiety
TARA for Medical Students, a Single-arm Mixed Methods Pilot Study
Medical students have higher risks for depression, anxiety, burnout and suicide than the general population and they rarely seek professional help or treatment.
- Conditions
- Depression, Anxiety, Stress-related Problem
- Trial name
- TARA (NCT05059392)
- Testing
- Training for Awareness, Resilience and Action (TARA)
- Where
- Sweden
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Umeå University
Financial Toxicity, Cancer Patients
Financial Toxicity, Quality of Life, and Caregiver Burden in Hospitalized Cancer Patients
This cross-sectional observational study evaluates the associations between patient-reported financial toxicity, health-related quality of life (HRQoL), and informal caregiver burden among hospitalized adult patients with solid…
- Trial name
- FIN-CARE (NCT07083271)
- Testing
- Administration of validated psychosocial, financial toxicity, and caregiver burden questionnaires
- Where
- Turkey (Türkiye)
- Volunteers
- 896 people
- Sponsor
- Ankara Etlik City Hospital
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