Clinical trials: Depression Symptom
Somatic Symptom
Efficacy and Safety of Toluedesvenlafaxine Hydrochloride Extended-release Tablets in Somatic Symptoms of Depression
The purpose of this study is to evaluate efficacy and safety of toludesvenlafaxine hydrochloride sustained-release tablets in the treatment of somatic symptoms in depression, to provide evidence-based basis for clinical rational…
- Trial name
- NCT05849272
- Testing
- toludesvenlafaxine hydrochloride sustained-release tablets
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Mental Health Center
Depressive Symptoms
Exploring the Effects of Strength Training on Depressive Symptoms and Cardiovascular Risk in Black Men
This study will address a gap in the literature and advance the field of minority men's health. Specifically, it will be the first randomized controlled trial of resistance exercise as a dual intervention for depression symptoms…
- Trial name
- NCT03107039
- Testing
- Exercise, Health Education
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Teachers College, Columbia University
Cardiovascular Diseases, Depression
Omega-3 Fatty Acids to Improve Depression and Reduce Cardiovascular Risk Factors
This study will determine the effects of omega-3 fatty acid (FA) augmentation of sertraline on depression and cardiac endpoints after myocardial infarction (MI).
- Conditions
- Cardiovascular Diseases, Depression, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00116857
- Testing
- Sertraline/omega-3, Sertraline/Corn Oil
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Washington University School of Medicine
Depression, Schizophrenia
Olanzapine Versus Active Comparator in the Treatment of Depression in Patients With Schizophrenia
This is a research study comparing the safety and efficacy of two active study medications
- Conditions
- Depression, Schizophrenia, Schizoaffective Disorder
- Trial name
- NCT00034801
- Testing
- olanzapine, ziprasidone
- Where
- 30 sites in United States
- Volunteers
- 378 people
- Sponsor
- Eli Lilly and Company
Screening Tool for Depresion in Cancer Pain Patients
The Edmonton Symptom Assessment System (ESAS) as a Screening Tool for Depression in Cancer Pain Patients
Compare Thai versions of the Edmonton Symptom Assessment System (ESAS) and the Hospiral Anxiety and Depression Scale (HADS) with Diagnostic and Statistical Manual (DSM-5), as a screening tool for depression in cancer pain patients
- Trial name
- NCT03686605
- Testing
- Thai version of the Edmontom Symptom Assessment System (ESAS)
- Where
- Thailand
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Major Depressive Disorder
Electroencephalography (EEG) Biomarkers of Response in Depression
There are two specific aims of this project: 1. To identify physiologic indicators of venlafaxine treatment response using quantitative EEG (QEEG) cordance, and to determine if cordance changes are specifically associated with…
- Trial name
- NCT00759122
- Testing
- venlafaxine (Effexor)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of California, Los Angeles
Depressive Disorder, Depressive Disorder, Major Depressive Disorder
Detection Algorithm for Recurrence or Relapse of Depression Thanks to a Smartwach
Globally, 3.8% of the population, or approximately 280 million people, suffer from depression. In France, 12.5% of adults experienced a major depressive episode (MDE) in 2021, with women being twice as affected as men.
- Conditions
- Depressive Disorder, Depressive Disorder, Major Depressive Disorder, Depressive Disorder Not Otherwise Specified (NOS)
- Trial name
- DALIA (NCT06789822)
- Testing
- Invitation to wear the smartwatch
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Dalia Care
Sleep Disturbance, Cognitive Change
Integrating Systematic Data of Geriatric Medicine to Explore the Solution for Health Aging
This project aims to build up the comprehensive database of geriatric medicine for local Taiwanese.
- Conditions
- Sleep Disturbance, Cognitive Change, Aging
- Trial name
- NCT04207502
- Where
- 2 sites in Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Major Depression, Bipolar Depression
Use of Ketamine to Enhance Electroconvulsive Therapy (ECT) in Depression
The primary objectives of this study are to investigate the potential for ketamine anesthesia to increase the antidepressant efficacy of Electroconvulsive therapy (ECT) and to decrease acute ECT-induced adverse cognitive effects.
- Trial name
- NCT01309581
- Testing
- Ketamine, Methohexital
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- James Murrough
Depression, Major Depressive Disorder
Transcranial Laser Therapy, Continuous and Pulsed Light, for Major Depressive Disorder (ELATED-3)
Transcranial Light Therapy involves non-invasive and invisible beams of light that increase energy metabolism in the brain. Transcranial light therapy has been found to promote brain metabolism which may help people with…
- Trial name
- ELATED-3 (NCT02959307)
- Testing
- Transcranial Light Therapy
- Where
- 2 sites in United States
- Volunteers
- 49 people
- Sponsor
- Massachusetts General Hospital
Depression, Anxiety
Mental Health and Resilience in Emerging Adulthood
The purpose of this study is to examine differences in selected psychiatric/psychological variables between a sample of unemployed young adults who have dropped out of high school and a sample of college students.
- Conditions
- Depression, Anxiety, Personality Disorders
- Trial name
- NCT01994122
- Where
- Norway
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Depression
Effects of Light Treatment During Sleep on Young Men
This study will determine if green light exposure during sleep is effective in reducing mild depression symptoms in young men.
- Trial name
- NCT00796939
- Testing
- Green light mask, Red Light Mask
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Depression, Depressive Symptoms
Predict Antidepressant Responsiveness Using Pharmacogenomics
The purpose of this study is to determine whether genetic information associated with individual depressive symptoms.
- Trial name
- NCT01228357
- Testing
- SSRI treated group, non-SSRI treated group
- Where
- South Korea
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Depression
Psycho-behavioral Intervention for Depression in Chronic Heart Failure
The study aims to explore the effectiveness of psycho-behavioral intervention on depressive symptoms among older adults with chronic heart failure.
- Trial name
- NCT03233451
- Testing
- Psycho-behavioral intervention
- Where
- 6 sites in China
- Volunteers
- 236 people
- Sponsor
- Peking University
Acute Pain
A Depression and Opioid Pragmatic Trial in Pharmacogenetics (Acute Pain Trial)
This study is comprised of three separate pharmacogenetic trials grouped into a single protocol due to similarities in the intervention, the hypotheses, and the trial design.
- Trial name
- ADOPT PGx (NCT05966129)
- Testing
- Pharmacogenetic testing, Clinical decisions support
- Where
- 11 sites in United States
- Volunteers
- 1,602 people
- Sponsor
- Duke University
Sudden Death
Sudden Death Counselling and Its Impact on Family Members of Sudden Death Victims
Assessment of the psychological benefit of the proposition by prehospital medical team of a sudden death counselling on family members of sudden death victims.
- Trial name
- SUIVIPROCHE (NCT03320902)
- Testing
- Sudden death counselling
- Where
- France
- Volunteers
- 625 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stress Disorders, Post-Traumatic, Depression
Psychological and Psychosocial Intervention With War-Affected Children
The investigators are interested in knowing whether a group-based, trauma-focused intervention (Trauma Focused Cognitive Behavioral Therapy) is superior to a more general, non trauma-focused, psychosocial intervention (Child…
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Anxiety, Conduct
- Trial name
- NCT01509872
- Testing
- Trauma Focused Cognitive Behavioral Therapy, Child Friendly Space
- Where
- Republic of the Congo
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Bipolar Disorder, Depression
Pediatric Bipolar Registry
The goal of the Pediatric Bipolar Registry (PBR) is to provide a comprehensive assessment regarding the diagnosis and treatment of pediatric bipolar disorder to children and adolescents with any current mood state and/or…
- Conditions
- Bipolar Disorder, Depression, Mania, Psychosis
- Trial name
- PBR (NCT02360267)
- Where
- United States
- Volunteers
- 334 people
- Sponsor
- The University of Texas Health Science Center, Houston
Adolescent Development
PPI to Promote the Psychological Well-being of Children Living in Poverty
Positive psychology interventions use positive psychology techniques to identify meaning and value in life events to raise positive feelings and emotions.
- Trial name
- NCT04875507
- Testing
- Positive Psychology
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Depression
rTMS in Treatment Resistant Depression
The purpose of this study is to determine the safety and efficacy of rTMS as an alternative treatment to ECT. The study will also provide data for a power analysis to support a larger clinical trial if there is evidence of a…
- Trial name
- rTMSECT (NCT02080507)
- Testing
- Active Neuronetics rTMS stimulator, Inactive Neuronetics rTMS stimulator
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Emory University
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