Clinical trials: Depression Symptom
Depression, Anxiety Disorders
MINDFUL-PC for Portuguese Speakers Pilot Study 2020
The study evaluates the effects of the Mindfulness Training for Primary Care (MTPC) Portuguese-adapted version on heart rate variability during a demanding cognitive task.
- Conditions
- Depression, Anxiety Disorders, Stress Related Disorder, Adjustment Disorders
- Trial name
- NCT04268355
- Testing
- Mindfulness Training for Primary Care
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cambridge Health Alliance
Major Depressive Disorder, Coronary Artery Disease
Vortioxetine in Patients With Major Depressive Disorder and Coronary Artery Disease
This is a preliminary, open-label, clinical trial designed to assess the efficacy, safety, and tolerability of vortioxetine for the treatment of major depressive disorder in patients with coronary artery disease.
- Trial name
- NCT02454426
- Testing
- Vortioxetine
- Where
- United States
- Sponsor
- Thomas Jefferson University
Anxiety, Depression
Group Music Therapy for Chinese Prisoners
The prevalence of psychological problems is high in prisons. Many prisoners have unmet needs for appropriate treatments. Although pilot studies have suggested music therapy to be a successful treatment modality for prisoners…
- Conditions
- Anxiety, Depression, Self-esteem
- Trial name
- NCT01633125
- Testing
- Group music therapy
- Where
- China
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Depressive Disorder, Major Depression
Pattern Separation, Brain Derived Neurotrophic Factors, and Mechanisms of Vortioxetine
The study is a 6-week, proof-of-concept, open trial of vortioxetine for 20 patients with major depressive disorder.
- Conditions
- Depressive Disorder, Major Depression, Depression, Depression, Unipolar
- Trial name
- VOR-IISR (NCT02969876)
- Testing
- Vortioxetine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Massachusetts General Hospital
Major Depressive Disorder
Targeting Specific Brain Networks to Treat Specific Symptoms in Depression
Repetitive transcranial magnetic stimulation (rTMS) is a way of non-invasively stimulating specific brain networks and is an established treatment for Major Depressive Disorder (MDD).
- Trial name
- NCT05523817
- Testing
- Intermittent Theta Burst Stimulation (iTBS)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Depression
Improving Depression Via E-Health Access (IDEA) Study
The researchers are doing this study to learn more about which online self-help resources, including a smartphone app, an online program, or an informational website, primary care patients with depression are likely to choose and…
- Trial name
- NCT04689568
- Testing
- Moodkit, Moodgym, University of Michigan Depression Center Toolkit
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Michigan
Long Covid, Depression
Development of an Accessible Cognitive Behavioral Therapy Digital Therapeutic for Individuals With Long COVID
This study will evaluate Toivoa-004 as an experimental digital therapeutic for persons with Long COVID suffering from anxiety or depression.
- Conditions
- Long Covid, Depression, Anxiety
- Trial name
- NCT07714889
- Testing
- Rauha® Digital Therapeutic Platform (Toivoa-004)
- Sponsor
- Toivoa Inc
Adjunctive Treatment of Major Depressive Disorder (MDD)
A Study of CLE-100 (Oral Esketamine) as an Adjunctive Treatment to Standard Antidepressants for Major Depressive Disorder
The study is a Phase 2, double-blind, randomized, placebo-controlled study in Major Depressive Disorder (MDD) participants with an inadequate response to standard antidepressants The objective of the study is to assess CLE-100…
- Trial name
- SOLEO (NCT06340958)
- Testing
- CLE-100
- Where
- 23 sites in United States
- Volunteers
- 99 people
- Sponsor
- Clexio Biosciences Ltd.
Unipolar Depressed Outpatients, Mild Severity
Effectiveness of the First French Psychoeducational Program on Unipolar Depression
Background. Major Depressive Disorder (MDD) is highly prevalent and was associated with greater morbidity, mortality (including suicide), and healthcare costs.
- Conditions
- Unipolar Depressed Outpatients, Mild Severity, Without Psychotic Features
- Trial name
- PURE (NCT02501226)
- Testing
- Treatment as usual, ENVIE psychoeducational program
- Where
- France
- Volunteers
- 332 people
- Sponsor
- University Hospital, Montpellier
Symptoms of Depression and Anxiety
Effectiveness of a Guided Mental Health Chatbot for Youth Living in Lithuania
The study aims to assess the effectiveness of a guided mental health chatbot called "Scalable Technology for Adolescents and youth to Reduce Stress (STARS)", adapted for youth living in Lithuania.
- Trial name
- NCT07012876
- Testing
- STARS (Scalable Technology for Adolescents and youth to Reduce Stress), Basic psychoeducation
- Where
- Lithuania
- Volunteers
- 262 people
- Sponsor
- Vilnius University
Depression, Postpartum, Labor Pain
CSE v. Epidural for Postpartum Depression
The purpose of this pilot prospective randomized control trial is to compare the initiation of labor epidural analgesia by combined spinal epidural vs. epidural for the influence on risk for postpartum depression symptoms.
- Trial name
- COPE (NCT03022526)
- Testing
- CSE, Epidural, Bupivacaine / fentaNYL
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Health Services for the Aged, Frailty
e-GAB: Electronic Geriatric Assessment Bundle: Development of an Arabic Self-administered Android CGA Application
The aim of this study is to design and assess the accuracy of administering the electronic Geriatric Assessment Bundle (e-GAB) compared to geriatrician performed comprehensive geriatric assessment (CGA) in a group of Egyptian…
- Conditions
- Health Services for the Aged, Frailty, Cognitive Impairment, Depression
- Trial name
- NCT04211285
- Testing
- e-GAB, standard physician performed CGA
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Major Depressive Disorder, Overweight
Omega-3 Fatty Acids for Major Depressive Disorder With High Inflammation: A Personalized Approach
This project aims to evaluate whether a dose-response relationship exists between dose of polyunsaturated fatty acids (PUFA), delivered as eicosapentaenoic acid (EPA), and change in markers of inflammation, and whether these…
- Conditions
- Major Depressive Disorder, Overweight, Inflammation
- Trial name
- NCT02553915
- Testing
- EPA 1 g/day, EPA 2 g/day, EPA 4 g/day
- Where
- 2 sites in United States
- Volunteers
- 61 people
- Sponsor
- Massachusetts General Hospital
Obesity, Morbid, Insulin Resistance
Stool Transplantation for Treatment of Insulin Resistance in Morbidly Obese Patients
More and more people in Canada and around the world are severely (morbidly) obese, and this is associated with a high risk for poor blood sugar control (insulin resistance, IR) and diabetes.
- Trial name
- NCT02970877
- Testing
- Fecal filtrate from 150 g stool from healthy lean donors, Fecal filtrate from 150 g of the recipient's own stool
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- Johane Allard
Low Back Pain, Disability Physical
Psychological Predictors of Pain and Disability in Patients With Chronic Low Back Pain After Manual Therapy
Low back pain has been reported to cause more disability than any other musculoskeletal health condition worldwide. About eight out of ten people will experience back pain at least once in their lifetime.
- Conditions
- Low Back Pain, Disability Physical, Manual Theapy
- Trial name
- NCT07306312
- Testing
- Manual therapy, Manual therapy plus Pain Neuroscience Education
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Thessaly
Depression, Depression, Postpartum
Chronobiology, Sleep Related Risk Factors and Light Therapy in Perinatal Depression: the Life-ON Project
In a 3 years longitudinal, observational, multicentre study, about 500 women will be recruited and followed-up from early pregnancy (10-15 gestational week) until 12 months after delivery.
- Conditions
- Depression, Depression, Postpartum, Depressive Disorder, Depressive Disorder, Major
- Trial name
- NCT02664467
- Testing
- Philips EnergyUp EnergyLight HF3419/01
- Where
- Switzerland
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Ospedale Regionale di Lugano
Depression, Anxiety
Mental Health E-screening in Pregnant and Postpartum Women
To compare e-screening versus usual screening on: 1) women's and healthcare providers' views on feasibility and acceptability; 2) rates of detection of prenatal and postpartum depression and anxiety; 3) perceived risk and benefit…
- Trial name
- NCT01899534
- Testing
- E-screening
- Where
- 3 sites in Canada
- Volunteers
- 566 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Diagnosis and Treatment of Depression
A Study of Diagnosis and Treatment of Depression Based on Biological Evidence of Dopamine Reward Pathway
This study will recruit depressed patients unresponsive to selective serotonin reuptake inhibitor antidepressant treatment, first-degree relatives (parents or siblings) of depressed patients, schizophrenia, Parkinson's disease…
- Trial name
- NCT03148509
- Testing
- risperidone, aripiprazole, bupropion
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Peking University
Depression
Assessment of Music Experiences in Navigating Depression
The study team sought to scientifically investigate strategic subsets of depressed individuals or people prone to or at-risk of depression through music experiences of individual, group, and blended supported contexts.
- Trial name
- AMEND (NCT06924892)
- Testing
- Music therapy, Wellness Concerts
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Depression
Suicidal Ideation and Behavior in Korean Adolescents With Depression
The purpose of this study is to examine clinical characteristics of Korean adolescents with depression who have suicidal ideation and behavior. We formulate those hypotheses. 1.
- Trial name
- NCT01314521
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Hallym University Medical Center
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