Clinical trials: Depression and Burden in Caregivers
Alzheimer Disease, Agitation,Psychomotor
Clinical Trial on Agitation in Alzheimer's Dementia
The purpose of this study is to assess the efficacy of the oral medication IGC-AD1, a THC-based (Delta-9-Tetrahydrocannabinol) formulation administered twice a day on Agitation in patients with mild to severe dementia from…
- Conditions
- Alzheimer Disease, Agitation,Psychomotor, Care Giving Burden, NPS
- Trial name
- CALMA (NCT05543681)
- Testing
- IGC-AD1-Active
- Where
- 28 sites in United States, Canada and 1 more
- Volunteers
- 164 people
- Sponsor
- IGC Pharma, LLC
Caregiver Burden, Self Efficacy
An Online Ecoaching RCT Intervention for Carers: Enhancing Wellbeing and Resilience Through Self-Help Strategies
The goal of this three-armed, double-blind randomized controlled trial (RCT) is to compare the effectiveness of an online self-help eCoaching intervention designed for caregivers.
- Conditions
- Caregiver Burden, Self Efficacy, Quality of Life, Anxiety Depression
- Trial name
- NCT06604481
- Testing
- eCoaching for Caregivers of Older Adults, eCoaching (need specific) for Caregivers of Older Adults, Control Intervention for Caregivers of Older Adults
- Where
- Hong Kong
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Stroke, Fatigue Syndrome, Chronic
Caregiver Burden and Psychological Outcomes in Caregivers of Stroke Patients With Lower Urinary Tract Symptoms
This cross-sectional observational study aims to evaluate caregiver burden, fatigue, sleep quality, and depression among family caregivers of stroke patients with lower urinary tract symptoms (LUTS).
- Conditions
- Stroke, Fatigue Syndrome, Chronic, Caregiver
- Trial name
- CARE-LUTS (NCT07480642)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Stress, Depression
Heart Failure Caregiver Study
Family caregivers are vulnerable to health problems because of the stress and demands of their role as a caregiver. With the growing incidence of heart failure (HF) and the anticipated growth in the aging population, the number…
- Trial name
- NCT01937936
- Testing
- Cognitive Behavioral Therapy (CBT), Health Education
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of California, Los Angeles
Diaper Rash, UTI
Diaper Distribution in Low-Income Infants
The adverse effects of poverty at the individual, family, and community level on health outcomes for children are well-established.
- Conditions
- Diaper Rash, UTI, Depressive Symptoms, Stress
- Trial name
- NCT03425851
- Testing
- Diapers, Resources of diaper banks
- Where
- United States
- Sponsor
- Boston Medical Center
Financial Toxicity, Cancer Patients
Financial Toxicity and Quality of Life in Hospitalized Cancer Patients: A Multicenter Study
This multicenter, cross-sectional observational study aims to evaluate the impact of financial toxicity on caregiver burden, quality of life, and emotional distress among hospitalized adult cancer patients.
- Trial name
- FIN-CARE (NCT07083271)
- Testing
- Administration of validated questionnaires with established Turkish versions
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 756 people
- Sponsor
- Ankara Etlik City Hospital
Compassion
Compassion-Based Intervention for Lung Cancer Caregivers (CBI-LCC)
Objectives: This 3-year study aims to develop, refine, and evaluate a brief compassion-based intervention specifically designed for family caregivers of lung cancer patients.
- Trial name
- CBI-LCC (NCT06930313)
- Testing
- Brief Compassion-Based Intervention (BCI), Telephone-Based Support and Education (TSE)
- Where
- Taiwan
- Volunteers
- 84 people
- Sponsor
- Taipei Medical University
Cerebral Palsy, Sleep Disorders in Children
Sleep Quality and Caregiver Burden in Children With Cerebral Palsy
Cerebral palsy (CP) is a lifelong condition affecting movement and posture, often requiring substantial care from family members.
- Conditions
- Cerebral Palsy, Sleep Disorders in Children, Caregiver Burden, Sleep Quality
- Trial name
- CP-SLEEP (NCT07168577)
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Selim Sezikli
Caregiver Burnout
Building Resilience In Caregivers of Trauma Survivors
The purpose of the study is to examine the role of demographics, pre-existing anxiety, depression, and substance use on caregiver depression anxiety, and substance use following a critical injury to a loved one, evaluate the…
- Trial name
- NCT04293016
- Testing
- Support as usual, Problem solving therapy, ICU diary
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke, Insomnia
Instant Message-delivered Cognitive Behavioural Therapy for Insomnia (CBT-I)Stroke Caregivers
The proposed trial aims to assess the effectiveness of Cognitive-behavioural therapy for insomnia (CBT-I) based ecological momentary intervention (EMI) for reducing insomnia symptoms among stroke caregivers.
- Conditions
- Stroke, Insomnia, Depressive Symptoms, Caregiver Burnout
- Trial name
- NCT05952245
- Testing
- iCBTI-based EMI, Education-based EMI
- Where
- 5 sites in Hong Kong
- Volunteers
- 138 people
- Sponsor
- The University of Hong Kong
Caregiver Burden, Dementia
Progressive Muscle Relaxation Exercise on Care Burden, Depression, Anxiety, and Stress Levels in Dementia Caregivers
Dementia, which leads to deterioration in cognitive and behavioral functions, is a chronic progressive disease. Since the diagnosis is made, the care needs of the patients increase.
- Trial name
- NCT06143826
- Testing
- Progressive muscle relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Atlas University
Alzheimer's Disease
Early Counseling and Support for Alzheimer's Disease Caregivers
This randomized trial evaluates the efficacy of counselling for reducing anxiety and depression in caregivers of patients with dementia.
- Trial name
- D_CareGiver (NCT02685787)
- Testing
- Psychosocial Intervention, Educational Intervention on AD
- Where
- Italy
- Volunteers
- 230 people
- Sponsor
- Azienda Sanitaria Locale N.1 dell'Umbria
Depressive Symptoms Mild to Moderate in Severity, Anxiety
Effects of Intranasal Ketamine on Depression and Anxiety in Palliative Care Cancer Patients
With progression of cancer, patients and their caregivers experience challenging emotional distress, which can make them feel depressed and very anxious. Patients with advanced cancer often do not have long to live.
- Conditions
- Depressive Symptoms Mild to Moderate in Severity, Anxiety, Quality of Life (QOL), Caregiver Burden
- Trial name
- Keta-Care (NCT06665568)
- Testing
- Intranasal ketamine hydrochloride
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Heart Failure, Caregiver Burden
Feasibility of the Heart to Heart Yoga Program
A two-group (intervention vs. usual care), randomized controlled design will be used to determine the feasibility and acceptability of the intervention, the Heart2Heart program, and determine efficacy on physical and…
- Conditions
- Heart Failure, Caregiver Burden, Depression, Anxiety
- Trial name
- H2HYoga (NCT05778747)
- Testing
- Heart to Heart Yoga
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Misook L. Chung
Palliative Care, Pain
Lysergic Acid Diethylamide (LSD) in Palliative Care
Background: Terminally ill patients often experience significant psychosocial distress having depressed mood, death anxiety, pain, and an overall poor quality of life.
- Conditions
- Palliative Care, Pain, Anxiety, Depression
- Trial name
- LPC (NCT05883540)
- Testing
- Lysergic Acid Diethylamide Tartrate
- Where
- 4 sites in Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Basel, Switzerland
Caregiver Burden, Stress
Supporting Mental Health and Reducing Care Stress in Caregivers of Persons With Cardiovascular Disease
The purpose of this study is to evaluate the preliminary efficacy, feasibility, acceptability, and barriers and facilitators to implementation of the Confident Caregiver intervention among family caregivers of persons with…
- Conditions
- Caregiver Burden, Stress, Depression, Anxiety
- Trial name
- NCT07717723
- Testing
- Confident Caregiver Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, Davis
Depression and Burden in Caregivers
Health-eBrain Study
The purposes of this study are to (1) track dementia caregiver health indicators over 12 weeks, both with and without the Mindoula plus DANA intervention (case manager and mobile messaging and assessment applications) to…
- Trial name
- HeB (NCT02903862)
- Testing
- Mindoula, DANA
- Where
- United States
- Sponsor
- AnthroTronix, Inc.
Amyotrophic Lateral Sclerosis
Anticipated Patient and Caregiver Burden
Amyotrophic lateral sclerosis (ALS) is a degenerative neurological disease that causes progressive motor disability and is life threatening within a few years.
- Trial name
- FARP (NCT05632757)
- Testing
- Psychological assessments
- Where
- France
- Volunteers
- 126 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Exercise, Gait
Rhythmically Entrained Exercise in Community-Dwelling Older Adults
Researchers at the University of North Carolina at Greensboro conduct a single-arm intervention trial to investigate the efficacy of a music-based group exercise program for community-dwelling older adults.
- Conditions
- Exercise, Gait, Cognitive Decline, Caregiver Burden
- Trial name
- REECO (NCT05462977)
- Testing
- Group exercise program
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Dementia, Alzheimer Disease (AD)
Impact of Musical Therapeutic Intervention on Depression in Dementia Patients and Caregiver Burden
This single-site interventional study evaluated the effects of receptive live music therapy on depression in patients with dementia and caregiver burden at the AMAVIDA Memory Care Unit in Fort Myers, Florida.
- Conditions
- Dementia, Alzheimer Disease (AD), Depression Chronic, Caregiver Burden of People With Dementia
- Trial name
- NCT07069530
- Testing
- Receptive Music Therapy
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Florida SouthWestern State College