Clinical trials: Depression and Quality of Life
Cardiology, Psychiatry
Effects of Aerobic Exercise on Cognition,Cerebral Brain Flow and Mental Health Among Traumatic Brain Injury Patients
The aim of this study is to develop exercise prescription of TBI patients and then to evaluate the effectiveness of programmed aerobic walking exercise to improve cognitive performance, depression relief, motivation, symptom…
- Trial name
- NCT04243226
- Testing
- telehealth-based aerobic walking exercise
- Where
- Taiwan
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
Mental Health Care, Depression Anxiety Disorder
Effectiveness of Exercise, Walking, and Education on Mental Health, Mobility and Quality of Life in Elderly Residents of Nursing Homes
Clinical Trial This clinical trial aims to determine the impact of physiotherapy interventions on mental health, quality of life, and spinal mobility in older adults.
- Conditions
- Mental Health Care, Depression Anxiety Disorder, Quality of Life
- Trial name
- NCT07236424
- Testing
- Physiotherapy
- Where
- Bosnia and Herzegovina
- Volunteers
- 44 people
- Sponsor
- University of Mostar
PCOS, Depression
Metformin, Vitamin D, and Depression in Polycystic Ovary Syndrome (PCOS) Trial
Open-label randomized clinical trial assessing the efficacy of Metformin versus Vitamin D in improving symptoms of depressed mood in polycystic ovary syndrome.
- Conditions
- PCOS, Depression, Vitamin D Deficiency, Insulin Resistance
- Trial name
- MINDD (NCT03380091)
- Testing
- Metformin, Vitamin D
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health
Ambient air temperatures in Asian, Latin American, African, and Pacific climate hotspots have broken record highs in 2024, driven by man-made climate change. Solutions are needed to reduce heat exposure in communities.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06579950)
- Testing
- Cool roof
- Where
- 5 sites in Burkina Faso, Fiji and 3 more
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Myasthenia Gravis, Adverse Childhood Experience
Psychological Health and Adverse Childhood Experiences in Myasthenia Gravis: Online Mental Health BMI Learning Program
This study evaluated psychological health in patients with myasthenia gravis (MG) using an online behavioral program called the "Positive Mental Health BMI Learning Program." The program consisted of four short video units…
- Conditions
- Myasthenia Gravis, Adverse Childhood Experience, Psychological Well-being, Mental Well-being
- Trial name
- NCT07291713
- Testing
- Positive Mental Health BMI Learning Program
- Where
- Taiwan
- Volunteers
- 77 people
- Sponsor
- Jiann-Horng Yeh
Post Intensive Care Syndrome, Depression
Companion Dog Walking for ICU Survivor Health
The goal of this clinical trial is to determine the feasibility and acceptability of a randomized controlled trial comparing a pet dog walking intervention to an attention control education intervention in adult intensive care…
- Conditions
- Post Intensive Care Syndrome, Depression, Anxiety, Quality of Life
- Trial name
- POOCH (NCT05820308)
- Testing
- Companion Dog Walking, Attention Control Group
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- University of Missouri, Kansas City
Intensive Care Unit Syndrome, Relatives
The Effectiveness of a Post-ICU Recovery Program on Relatives
Relatives of intensive care patients are at risk of developing symptoms of anxiety, depression and post-traumatic stress disorder resulting in impaired health-related quality of life (HRQOL).
- Trial name
- RAPIT-II (NCT03264365)
- Testing
- Intervention
- Where
- Denmark
- Volunteers
- 181 people
- Sponsor
- Holbaek Sygehus
Multiple Sclerosis, Quality of Life
Impact of Exercise on "Invisible" Symptoms and Quality of Life in Multiple Sclerosis Individuals
Patients with multiple sclerosis (MS) struggle on a daily basis with accompanying, "Invisible" symptoms like primary fatigue, pain and emotional-cognitive disorders.
- Conditions
- Multiple Sclerosis, Quality of Life, Motivation, Pain
- Trial name
- NCT03768830
- Testing
- Exercise training
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rijeka
Preventive Intervention
Preventive Intervention to Promote Healthy Ageing
The aim of the project is the support of healthy ageing of older adults in acommunity. Efficient educational and psychosocial intervention will besuggested and verified to prevent anxiety, depression, and cognitivedisorders of…
- Trial name
- NCT05637177
- Testing
- Anging Wisely, Music therapy, Reminiscence therapy
- Where
- Czechia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Ostrava
Freeman-Burian Syndrome, Freeman-Sheldon Syndrome
Survey Study and Records Review of Treatment Outcomes in Freeman-Sheldon Syndrome
The purpose of this study is to evaluate the difference in diagnosis accuracy, treatment outcomes, patient perspectives, facial function and walking ability, emotional and social health, and respiratory complications between…
- Conditions
- Freeman-Burian Syndrome, Freeman-Sheldon Syndrome, Whistling Face Syndrome, Sheldon-Hall Syndrome
- Trial name
- FINDFSS (NCT05419245)
- Testing
- Guided Health History for Freeman-Burian Syndrome Questionnaire, Freeman-Burian syndrome Semi-Structured Quality of Life Interview, Medical Records Review
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Lung Cancer, Depression
Exercise Program Among Lung Cancer Dyads
Pilot study of an exercise program among patients with all stages of lung cancer examining feasibility and acceptability. Preliminary outcomes include objective measures of physical function, depression, adherence to lung cancer…
- Conditions
- Lung Cancer, Depression, Physical Activity, Quality of Life
- Trial name
- PEP-LC (NCT03649737)
- Testing
- Exercise Intervention, Survey Administration, Quality-of-Life Assessment
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- OHSU Knight Cancer Institute
Cancer, Coping Skills
Mindfully Optimizing Delivery of End-of-Life Care
The study evaluates the feasibility, acceptability, and preliminary efficacy of a mindfulness meditation-based intervention designed to provide a synergistic solution to the avoidant coping that often inhibits advance care…
- Trial name
- MODEL Care (NCT02367508)
- Testing
- MODEL Care
- Volunteers
- 31 people
- Sponsor
- Indiana University
Parkinson Disease, Pilates
Effect of Pilates Application on Abdominal Muscle Function, Core Stability, Musculoskeletal Pain, Quality of Life, Anxiety and Depression in Parkinson's Patients
In this study, it is aimed to investigate the effect of Pilates application on abdominal muscle function, core stability, musculoskeletal pain, quality of life, anxiety and depression in Parkinson's Patients.
- Conditions
- Parkinson Disease, Pilates, Muscle Function
- Trial name
- NCT04619784
- Testing
- Pilates Exercises, control
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Dokuz Eylul University
SARS-CoV2 Infection
Receptive Music Therapy on Anxiety and Vital Parameters in Hospitalized Covid-19 Patients.
Hospitalized patients for Covid-19 are extremely isolated from their families for a long and uncertain period of time .This traumatic separation makes patients vulnerable to different degrees of stress disorders as well as…
- Trial name
- MADC-19 (NCT05077306)
- Testing
- music therapy group
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Anxiety, Hospitalization
Virtual Nature Versus Guided Imagery for Anxiety and Well-Being in Hospitalized Older Adults
Long hospital stays can be difficult for older adults. Being confined to a ward, with limited mobility and little access to the outdoors, may contribute to anxiety, low mood, and reduced well-being.
- Conditions
- Anxiety, Hospitalization, Quality of Life, Psychological Distress
- Trial name
- NCT07765355
- Testing
- Immersive virtual reality nature exposure, Guided imagery
- Where
- 2 sites in Hungary
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Quality of Life (QOL), Mental Wellbeing
Arts for Wellness (AFW): Arts-Based Social Prescribing During Inpatient Rehabilitation for Older Adults in Singapore
This mixed-methods study examined whether Arts for Wellness (AFW), an artist-led arts programme introduced during inpatient rehabilitation, improves mental wellbeing among older adults in a Singapore community hospital, and…
- Conditions
- Quality of Life (QOL), Mental Wellbeing, Anxiety, Depression
- Trial name
- SPNAC (NCT07851467)
- Testing
- Arts for Wellness - Dance, Arts for Wellness - Literary arts
- Where
- Singapore
- Volunteers
- 288 people
- Sponsor
- SingHealth Community Hospitals
Breast Cancer, Prostate Cancer
A Pilot Study of Geriatric Specific Interventions for Quality of Life in Elderly Patients With Cancer
The purpose of this study is to examine whether psychoeducation counseling for older cancer patients undergoing treatment is feasible and worthwhile.
- Conditions
- Breast Cancer, Prostate Cancer, Lung Cancer, Lymphoma Cancer
- Trial name
- NCT00984321
- Testing
- group intervention and questionnaires, individual phone intervention and questionnaires, expressive writing (arm will not be include in the randomization)
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
COPD, Quality of Life
Psychological Distress in Patients With COPD
Chronic obstructive pulmonary disease (COPD) can significantly impact a person's quality of life, not only physically but also mentally.
- Conditions
- COPD, Quality of Life, Mental Health, Psychological Distress
- Trial name
- NCT06395311
- Testing
- COPD psychological well-being assessment
- Where
- Romania
- Volunteers
- 98 people
- Sponsor
- Spitalul Clinic de Boli Infecțioase și Pneumoftiziologie Dr. Victor Babeș Timișoara
Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia
Ozone Treatment in Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral Neuropathy
The goal of this phase II/III randomized clinical trial is to evaluate the effect of adding rectal ozone therapy to the usual management of patients with paresthesia (numbness and/or tingling) due to chemotherapy-induced…
- Conditions
- Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia, Numbness, Tingling
- Trial name
- OzoParQT (NCT06706544)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Gastric Cancer
Effectiveness of Exercise Program in Improving Quality of Life in Patients With Gastric Cancer Undergoing Gastrectomy
This study will investigate the effectiveness of a rehabilitation program in improving fatigue, negative emotions , sleep quality, circadian rhythms and quality of life in patients with gastric cancer undergoing gastrectomy in…
- Trial name
- NCT04593134
- Testing
- exercise group
- Where
- Taiwan
- Volunteers
- 160 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan