Clinical trials: Depression and Quality of Life
Schizophrenia, Major Depressive Disorder
Clinical Registry of Patients Under Treatment With Atypical Antipsychotics
Antipsychotic drugs are characterized by blocking dopaminergic D2 receptors. They have been found to be effective and safe for the treatment of schizophrenia, bipolar disorders, depressive episodes associated with bipolar…
- Conditions
- Schizophrenia, Major Depressive Disorder, Bipolar Depressive Disorder, Parkinson's Disease With Hallucinations
- Trial name
- NCT02409823
- Testing
- Atypical Antipsychotics
- Volunteers
- 665 people
- Sponsor
- Pontifical Catholic University of Argentina
Rheumatoid Arthritis
Assessment of Anxiety, Depression, Sleep Quality and Quality of Life in Rheumatoid Arthritis Patients
The goal of this case control observational study is to asses anxiety, sleep, depression and quality of life in rheumatoid arthritis patients The main aims are: asses anxiety, sleep, depression and quality of life in rheumatoid…
- Trial name
- NCT05957770
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Depression
Depression Online Assessment and Therapy
One Aim of the current study is to better understand why some patients suffering from depression do not seek professional help by doctors but in the internet.
- Trial name
- NCT02112266
- Testing
- Mail support, no mail support
- Where
- Switzerland
- Volunteers
- 272 people
- Sponsor
- University of Zurich
Gastrointestinal Neoplasms
Sleep Disturbance, Depressive Symptoms, and Subsequent Quality of Life During Adjuvant Chemotherapy for Gastrointestinal Cancer
This prospective, single-center, non-interventional observational cohort study evaluated longitudinal changes in sleep quality, depressive symptoms, and health-related quality of life among adults receiving fluoropyrimidine-based…
- Trial name
- TRACE-GI (NCT06996483)
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 198 people
- Sponsor
- Ankara Etlik City Hospital
Major Depressive Disorder
Effect of Physical Activity on Depressive Symptoms With a 5 Month Follow-up
The main objective of this study is to evaluate the effect of a 12 weeks adapted physical activity program (active walking) on depression by analyzing the dynamics of emotional and cognitive functioning.
- Trial name
- 2DPAP (NCT01995422)
- Testing
- Physical activity program
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Laboratory Motricité, Interactions, Performance
Rheumatoid Arthritis, Sleep Quality
The Effects of Exercise on Serum BDNF and Irisin Levels in Patients With Rheumatoid Arthritis
The aim of our study is to investigate the effects of aerobic exercise on sleep quality, fatigue, quality of life, depression and serum BDNF and irisin levels, which are important biomarkers of sleep in patients with rheumatoid…
- Conditions
- Rheumatoid Arthritis, Sleep Quality, Aerobic Exercise
- Trial name
- NCT05546294
- Testing
- Aerobic and home exercise, Home exercise, Healthy control group
- Where
- Turkey (Türkiye)
- Volunteers
- 151 people
- Sponsor
- Afyonkarahisar Health Sciences University
Stroke
Meditation and Biofeedback to Improve Anxiety, Depression and Quality of Life in Inpatients After Stroke
The goal of this clinical trial is to investigate the impact of a technology-based meditation program in the inpatient stroke population.
- Trial name
- NCT05845541
- Testing
- Technology Supported Meditation and Biofeedback, Standard Treatment
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Depression
The Effect of Duloxetine on Mood, Quality of Life and Cognitive Functioning in Glioblastoma Patients
Primary tumor glioblastoma is the most common malignant brain. Standard treatment includes biopsy or excision of the tumor in order to obtain a pathological diagnosis, and tumor mass reduction.
- Trial name
- NCT02443194
- Testing
- duloxetine
- Volunteers
- 50 people
- Sponsor
- michal roll
Depression, Quality of Life
Quality of Life and Self-esteem After Botox® Injections in Depressed and Non-depressed Patients
The primary objective of this study is to determine the alterations in quality of life and self-esteem after BOTOX® injections in the glabella in depressed and non-depressed patients.
- Trial name
- NCT01004042
- Testing
- Botulinum Toxin Type A
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hexsel Dermatology Clinic
Post-COVID Condition
Nutritional Intervention and Rehabilitation Treatment in Patients With Post-COVID Condition
SARS-CoV-2 is the coronavirus responsible for developing the disease known as COVID-19. Once the acute phase of the disease has passed, about 40% of the people who discharged continue to have symptoms, and of these, between 50…
- Trial name
- ARACOV-02 (NCT06063031)
- Testing
- Active
- Where
- Spain
- Volunteers
- 146 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Anxiety, Depression
Brief CBT for Anxiety and Advanced Cancer
RATIONALE: Providing cognitive-behavioral therapy (CBT) may reduce anxiety and improve quality of life of patients with advanced cancer.
- Conditions
- Anxiety, Depression, Unspecified Adult Solid Tumor, Protocol Specific, Cancer
- Trial name
- NCT00706290
- Testing
- Brief Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Massachusetts General Hospital
Postnatal Depression, Self Efficacy
Comparative Effect of Training on Postpartum Depression
New mothers experience postpartum depression after childbirth, which commonly include mood swings, crying spells, anxiety and difficulty sleeping.
- Trial name
- NCT05891717
- Testing
- Resistance training, Flexibility training
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Spinal Cord Injuries (SCI), Chronic Pain
Virtual Reality-Based Hypnotherapy for Pain, Sleep, and Mood in Spinal Cord Injury
The goal of this clinical trial is to learn whether virtual reality (VR)-based hypnotherapy, added to conventional physiotherapy, improves pain, sleep, mood, and quality of life in adults with chronic spinal cord injury.
- Conditions
- Spinal Cord Injuries (SCI), Chronic Pain, Neuropathic Pain, Sleep Disturbance
- Trial name
- HypnoVR-SCI (NCT07846410)
- Testing
- Virtual Reality-Based Hypnotherapy, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Fibromyalgia
THE EFFECT OF CHIROPRACTIC THORACIC MANIPULATION ON PAIN, DEPRESSION, SLEEP AND QUALITY OF LIFE IN PATIENTS WITH FIBROMYALGIA
This study aimed to investigate the effects of thoracic chiropractic manipulations on pain intensity, depression levels, sleep, and quality of life in women diagnosed with fibromyalgia.
- Trial name
- NCT06194942
- Testing
- chiropractic manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Bahçeşehir University
Obesity, Well-being
Activation of Young Men - Population-Based Randomised Controlled Trial
The aim of the study is to investigate different novel IC technologies for promoting physical activity and health and preventing obesity in young men.
- Conditions
- Obesity, Well-being, Quality of Life, Depression
- Trial name
- MOPO (NCT01376986)
- Testing
- physical, psychological and social activation
- Where
- Finland
- Volunteers
- 507 people
- Sponsor
- University of Oulu
Parkinson Disease, Depression
Improving Quality of Life in Early Parkinson's Disease
The study will examine 30 patients between ages 50-80, newly diagnosed with early-stage Parkinson's Disease. Patients will be randomized to receive either Citalopram or Carbidopa-levodopa.
- Trial name
- PD QOL (NCT04590612)
- Testing
- Carbidopa-Levodopa 25 Mg-100 Mg Oral Tablet, Citalopram
- Volunteers
- 30 people
- Sponsor
- Western University, Canada
Diabetic Peripheral Neuropathy
Effect of an Exercise Program on Clinical Aspects of People With Diabetic Peripheral Neuropathy
Diabetic Peripheral Neuropathy (DPN) is one of the most prevalent and debilitating complications of type 2 diabetes mellitus (DM2), especially affecting the distal region of the lower limbs.
- Trial name
- NCT07075367
- Testing
- Proximal/distal protocol, Distal protocol
- Volunteers
- 64 people
- Sponsor
- Federal University of Piaui
Depression, Social Stress
Community Resilience Learning Collaborative and Research Network
C-LEARN is designed to determine how to build service program and individual client capacity to improve mental health-related quality of life among individuals at risk for depression, with exposure to social risk factors or…
- Conditions
- Depression, Social Stress, Anxiety, Quality of Life
- Trial name
- C-LEARN (NCT03977844)
- Testing
- Technical Assistance, Community Engagement and Planning, Community Resources (CR)
- Where
- United States
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Cervical Myofascial Pain Syndrome, Chronic Neck Pain
Type D Personality, and Stigma in Myofascial Pain Syndrome
Cervical myofascial pain syndrome is a chronic musculoskeletal condition characterized by the presence of sensitive trigger points and taut muscle bands, resulting in localized or referred pain, muscle stiffness, and limited…
- Conditions
- Cervical Myofascial Pain Syndrome, Chronic Neck Pain, Type D Personality, Psychological Distress
- Trial name
- NCT07292155
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Gulseren Demir Karakilic
HIV/AIDS
Antiretroviral Adherence and Quality-of-life Support for HIV+ Patients in India With Twice-daily Interactive Voice Response (IVR) Calls With Health and Mental Health Messaging Compared to Weekly IVR Survey Only Control Condition: The Mobile-messaging Adherence and Support for Health Study, India.
The purpose of this study is to test whether twice-daily Interactive Voice Response (IVR) calls made at the estimated times of patients' antiretroviral (ART) medication dosing and three reminder calls for monthly clinic…
- Trial name
- MASHIndia (NCT02118454)
- Testing
- Daily IVR Calls Intervention, Weekly IVR Survey Only
- Where
- 2 sites in India
- Volunteers
- 400 people
- Sponsor
- University of California, Los Angeles