Clinical trials: Depression and Quality of Life
Glaucoma, Depression
Impact of Breathing Exercises and Meditation on Improving Quality of Life in Glaucoma Patients
Glaucoma is a chronic disease that causes loss of vision and potentially blindness as a result of optic nerve damage, often due to increased intraocular pressure.
- Conditions
- Glaucoma, Depression, Anxiety, Quality of Life
- Trial name
- NCT05960513
- Testing
- Breathing Exercises followed by Meditation
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Irritable Bowel Syndrome, Constipation
Cognitive Behaviour Therapy for Patients With IBS
Irritable bowel syndrome (IBS) affects approximately 10-15% of the adult population. This condition is characterized by abdominal pain, altered bowel habit, abdominal bloating and reduced quality of life.
- Conditions
- Irritable Bowel Syndrome, Constipation, Abdominal Pain, Depression
- Trial name
- EFI (NCT00788658)
- Testing
- Diet modifications, Cognitive behavioral therapy
- Volunteers
- 100 people
- Sponsor
- Rabin Medical Center
Posttraumatic Stress Disorder, Depression
A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Pilot
The goal of this pilot study is to develop and implement a larger scale, multi-site stepped collaborative care trial that targets injured patients with presentations of posttraumatic stress disorder (PTSD) and related…
- Conditions
- Posttraumatic Stress Disorder, Depression, Alcohol-Related Disorders, Suicidal Ideation
- Trial name
- TSOS6 (NCT02335125)
- Testing
- Motivational Interviewing, Cognitive Behavioral Therapy Elements, Psychotropic Drugs
- Volunteers
- 40 people
- Sponsor
- University of Washington
Major Depression
Deep Brain Stimulation of the Superolateral Branch of the Medial Forebrain Bundle (slMFB) for the Treatment of Refractory Major Depression
The investigators will investigate in a sham controlled staggered onset design antidepressant effects and safety of deep brain stimulation (DBS) to the superolateral branch of the main medial forebrain bundle (slMFB).
- Trial name
- FORESEEII (NCT01778790)
- Testing
- Deep Brain Stimulation with Activa PC Multi-program Neurostimulator
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- University Hospital, Bonn
Sedation, Mechanical Ventilation
Sedation and Psychopharmacology in Critical Care
Certain methods of sedation increase the duration of respiratory failure. Two strategies, a nursing- implemented sedation algorithm and daily interruption of sedatives, decrease length of mechanical ventilation compared to…
- Conditions
- Sedation, Mechanical Ventilation, Depression, Post-traumatic Stress Disorder
- Trial name
- NCT00205517
- Testing
- Daily interruption of sedation versus sedation algorithm
- Volunteers
- 75 people
- Sponsor
- Virginia Commonwealth University
Acute Coronary Syndrome, Depressive Symptoms
Comparison of Depression Identification After Acute Coronary Syndrome: Quality of Life and Cost Outcomes
The purpose of this study is to examine, in a randomized controlled trial, the benefits and costs of the American Heart Association's (AHA) advisory for depression screen and treatment of post-acute coronary syndrome patients.
- Trial name
- CODIACSQoL (NCT01993017)
- Testing
- Cognitive Behavioral Therapy (CBT), Antidepressant Medication, Standard Care
- Where
- 4 sites in United States
- Volunteers
- 1,501 people
- Sponsor
- Columbia University
Caregivers of People With Dementia, Quality of Life
Mindfulness-Based VR for Family Caregivers of People With Dementia
The goal of this clinical trial is to explore the effectiveness of mindfulness-based VR could enhance depression, sleep quality, and overall quality of life for family caregivers providing care for people with dementia.
- Trial name
- NCT06034249
- Testing
- Mindfulness-Based VR, Audio
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Post-Intensive Care Syndrome, Anxiety
Family and Patient Outcomes After Pediatric Intensive Care (FOREVER)
This study aims to evaluate in the Brazilian context, the impact of the implementation of a diary program on patient and family-centered outcomes after PICU discharge.
- Conditions
- Post-Intensive Care Syndrome, Anxiety, Depression, Stress Disorders, Post-Traumatic
- Trial name
- FOREVER (NCT04961697)
- Testing
- Hospital diaries
- Where
- Brazil
- Volunteers
- 431 people
- Sponsor
- D'Or Institute for Research and Education
Depressive Symptoms, Depression
Efficacy of an Online Self-help Program for Negative Affect and Depression
The aim of the study is to test Body, breath \& mind (BBM, internet-based self-help program) for its efficacy in reducing depressive symptoms and improving quality of life.
- Trial name
- NCT05293691
- Testing
- Body, Breath & Mind, Moodgym
- Where
- Germany
- Volunteers
- 303 people
- Sponsor
- University of Witten/Herdecke
Comparison of Aerobic Exercise and Resistance Training
Comparison of Aerobic and Resistance Training on Exercise Capacity, Depression and Quality of Life in Hypothyroidism.
the study will show the effects of aerobic and resistance training on exercise capacity, depression and quality of life in patients with hypothyroidism.
- Trial name
- NCT06377826
- Testing
- aerobic exercises, resistance training, medication
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Riphah International University
Insomnia, Insomnia Chronic
Assessment of Sleep Quality and Mental Health After Using Meditation
This is a randomized controlled trial that intends to verify the effectiveness of the daily practice of meditation before going to sleep for the improvement of sleep, stress, mental health and quality of life of people with sleep…
- Conditions
- Insomnia, Insomnia Chronic, Insomnia Disorder, Sleep Disorder
- Trial name
- NCT05812443
- Testing
- Shabad Kriya Meditation, Relaxing reading
- Where
- Brazil
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Cardiac Rehabilitation, Coronary Artery Bypass Surgery
Cardiac Rehabilitation After Coronary Artery Bypass Graft Surgery
This study aimed to evaluate the effects of cardiac rehabilitation program after CABG surgery on quality of life, sleep quality, anxiety, depression and cardiopulmonary functions.
- Trial name
- NCT06970938
- Testing
- Cardiac rehabilitation program
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Muhammed Onur Hanedan
Hematological Neoplasm, Graft-Versus-Host Disease
The Influence of TaKeTiNa Music Therapy, Traditional Chinese Acupuncture and Clown Theatrical Performance on Quality of Life and the Therapeutic Process of Patients Undergoing Allogenic Stem Cell Transplantation
The allogenic stem cell transplantation (aSCT), the only curative approach for many hematological diseases, often leads to severe diseases or chronic conditions, leaving patients with physical disabilities and severe depression…
- Conditions
- Hematological Neoplasm, Graft-Versus-Host Disease, Depression, Stem Cell Transplant Complications
- Trial name
- TriCAM (NCT02976558)
- Testing
- Clown theatrical Performance, Acupuncture, Music Therapy TaKeTiNa
- Where
- Germany
- Volunteers
- 104 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Infertility, Female
The Effect of the Mind/Body Program for Fertility, Hungarian Version, on Well-Being and Assisted Reproduction Outcomes
Involuntary childlessness is an emotionally stressful experience; however, psychosocial counseling is typically not available in Hungarian routine fertility care.
- Trial name
- NCT04151485
- Testing
- Mind/Body Program for Fertility (Domar et al., 2011), Fertility Support Program
- Where
- 2 sites in Hungary
- Volunteers
- 177 people
- Sponsor
- Semmelweis University
Quality of Life
Improving Quality of Life in Nursing Home Residents: A Cluster Randomized Clinical Trial of Efficacy
Improving quality of life (QoL) in residents of nursing homes: A cluster randomized clinical trial of efficacy - The KOSMOS study.
- Trial name
- KOSMOS (NCT02238652)
- Testing
- Communication, Systematic Pain Assessment and Treatment, Medication Review
- Where
- 32 sites in Norway
- Volunteers
- 560 people
- Sponsor
- University of Bergen
Cardiac Arrest (CA)
Effects of a Web-based Support Programme for Cardiac Arrest Survivors
The overall goal of this clinical trial is to learn if a web-based support programme can improve wellbeing in cardiac arrest survivors by helping them manage emotional, cognitive, and physical challenges.
- Trial name
- CARDIS (NCT07240714)
- Testing
- Digital Support Programme
- Where
- 9 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Linkoeping University
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Niue
Ambient air temperatures in the Pacific have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06570993)
- Testing
- Cool roof
- Where
- Niue
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Post Traumatic Stress Disorder, Adjustment Disorder
Psychological First Aid With Children in a High Risk Group - a Repeated Single Case Design
The purpose of this pilot-study is to evaluate a cognitive behavioral method "Psychological First Aid" used with a group of children (11-16 years) in high risk of developing psychological problems.
- Trial name
- NCT01612104
- Testing
- Psychological First Aid
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- NORCE Norwegian Research Centre AS
Infertility, Female, Anxiety State
Women's Quality of Life, Sexual Life and Psychological State in Patients Undergoing Embryo Transfers
Women's quality of life, sexual life and psychological state would affect the success of embryo transfer. The primary purpose of the study is to compare women's quality of life, sexual life and psychological state using validated…
- Conditions
- Infertility, Female, Anxiety State, Depression, Quality of Life
- Trial name
- NCT04131452
- Testing
- Filling out the forms including IDAS-II, BAI, SF-36 and FSFI
- Where
- Turkey (Türkiye)
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Bahceci Health Group
Exercise
Effects Multi-Gravitational Suspension-Based Therapy
Background: Multi-gravitational suspension-based therapy (M-Gravity) is a comprehensive discipline based on the principles of non-gravity, which serves to increase the quality of life and holistic health of the individual with…
- Trial name
- NCT05317650
- Testing
- Multi-gravitational suspension-based therapy (M-Gravity)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Atlas University