Clinical trials: Depression and Quality of Life
Cardiovascular Diseases, Coronary Artery Disease
Depressive Symptoms After Cardiac Surgery
The primary goal of this project is to develop a predictive model for clinically significant depressive symptoms (CSDS) in patients undergoing coronary artery bypass graft (CABG) surgery, using pre- and perioperative data.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Heart Diseases, Depression
- Trial name
- PCD (NCT06706323)
- Where
- 2 sites in Switzerland
- Volunteers
- 300 people
- Sponsor
- Roland von Känel
Mental Health, Physical Health
Parental Well-being After Childbirth in Switzerland
Improving maternal and child health is a global priority, with increasing emphasis on ensuring women and their families not only survive but also thrive after childbirth.
- Conditions
- Mental Health, Physical Health, Postpartum, Parents
- Trial name
- SOCRATES (NCT06886841)
- Where
- 2 sites in Switzerland
- Volunteers
- 4,200 people
- Sponsor
- Laurent Gaucher
Breast Neoplasms, Quality of Life
Breast Cancer and Resilience in Couple
This is a prospective pilot study examining the couple's dyadic attitudes from diagnosis to 24 months later when one member is affected by illness and the adaptive strategies the couple employs when stressful events occur.
- Trial name
- resilience (NCT06875414)
- Testing
- Nursing care model
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Regina Elena Cancer Institute
Fatigue, Depression, Anxiety
Fatigue As a Late Effect in Breast Cancer Survivors - is Acupuncture a Treatment Option?
The success of treatment of breast cancer has improved, hence the prevalence of survivors have increased. However, experienced late effects from the cancer itself or from cancer treatment is substantial.
- Conditions
- Fatigue, Depression, Anxiety, Insomnia, Hot Flashes
- Trial name
- NCT04418115
- Testing
- Acupuncture; based on Tradidtional Chinese Medicine
- Where
- Norway
- Volunteers
- 223 people
- Sponsor
- Kristiania University College
Depression, Quality of Life
Intervention for Rural Cancer Patients
In an effort to reduce rural-urban disparities and improve the quality of cancer care for these patients, the objectives of this study will be to: (1) adapt the intervention to maximize effectiveness for rural, low-income…
- Conditions
- Depression, Quality of Life, Social Support, Sleep
- Trial name
- NCT05091593
- Testing
- Stepped collaborative care intervention, Enhanced Usual Care
- Where
- United States
- Sponsor
- University of Pittsburgh
Mental Health Issue, Depression/Anxiety
Psychiatric Consultation-Liaison Intervention in Primary Care: A Pilot Study
The pilot study on the impact of a Psychiatric Consultation-Liaison Intervention in Primary Care Medical Consultations in French-speaking Switzerland (PLIMeC-P), is a mixed method randomized controlled trial.
- Conditions
- Mental Health Issue, Depression/Anxiety, Quality of Life, Psychosomatic Disorders
- Trial name
- PLIMeC-P (NCT06377189)
- Testing
- Intervention arm - Consultation-Liaison (CL) brief psychiatric intervention in primary care settings, Control Arm - Treatment As Usual (TAU)
- Where
- 3 sites in Switzerland
- Volunteers
- 30 people
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Primary Headache, Psychological Distress
Impact of MBI on Biopsychosocial Factors and QOL in Children With Primary Headaches
The Randomized Controlled Trial aims to evaluate the effectiveness of a Mindfulness-Based Intervention (MBI) in improving the quality of life and reducing psychological distress in children with primary headaches.
- Conditions
- Primary Headache, Psychological Distress, Emotion Regulation, Childhood Trauma
- Trial name
- NCT06822673
- Testing
- Mindfulness Based Intervention
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatima Jinnah Women University
Depression, Anxiety
SALSA (Health, Food and Sociability): Community Networks for Healthy Eating, Autonomy, and Social Interaction
Antecedents: Unwanted loneliness is associated with an increased risk of anxiety, depression, social isolation, and malnutrition.
- Conditions
- Depression, Anxiety, Social Support (Formal and Informal), Quality of Life (QOL)
- Trial name
- SALSA (NCT06800027)
- Testing
- SALSA group intervention: Going to lunch at the restaurant in a group and attending healthy eating workshops.
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Depression, Cancer Patients and Depression and Suicide
Improvement of Depression in Terminal Cancer Patients
This study investigates the potential of the water extract of Gastrodia elata Blume (WGE) to alleviate depressive symptoms in terminal cancer patients.
- Conditions
- Depression, Cancer Patients and Depression and Suicide, Life Quality
- Trial name
- IDTCP (NCT06785623)
- Testing
- Gastrodia elata Blume water extract
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Depressive Symptoms, Depression
Efficacy and Safety of Auricular Acupuncture in Depression During the Covid 19 Pandemic
Participants with moderate depressive symptoms measured by PHQ-9 will be randomized to receive auricular acupuncture. The triple blinded procedure will be conducted in 12 sessions (6 weeks).
- Conditions
- Depressive Symptoms, Depression, Anxiety, Insomnia
- Trial name
- NCT05855421
- Testing
- Auricular Acupuncture
- Where
- Brazil
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Universidade do Sul de Santa Catarina
Neck Pain, Quality of Life
Chronic Non-Specific Neck Pain and Quality of Life
The factors affecting the quality of life in individuals with chronic non-specific neck pain are not fully known in the studies conducted to date.
- Trial name
- NCT06777862
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Trauma, Psychological, Depression, Anxiety
Validation of a Dance as Therapy Program in Co-facilitation
The objective is to validate a psychotherapeutic group protocol of dance as therapy created by LOBA association with a comparative non-randomized study.
- Conditions
- Trauma, Psychological, Depression, Anxiety, Stress, Body Image
- Trial name
- VaDDanC (NCT06027658)
- Testing
- RECREATION therapy
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Franche-Comté
Health Behavior, Quality of Life
The Lake Nona Life Project
The Lake Nona Life Project aims to examine the health and wellness of participants over the course of multiple years, focusing on the links between health and wellness, longevity, quality of life, and human performance.
- Conditions
- Health Behavior, Quality of Life, Aging
- Trial name
- NCT02533804
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Melanoma, Cognitive Impairment
Cognitive Function in Melanoma Patients Treated With Adjuvant Immune Checkpoint Inhibitors
Immune checkpoint inhibitors (ICIs) are a group of novel immunotherapies that boost the body's own defense against the cancer by improving the immune system's ability to recognize and destroy cancer cells.
- Conditions
- Melanoma, Cognitive Impairment, Fatigue, Sleep
- Trial name
- NCT04565769
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Caregiver Burden, Behavioral and Psychiatric Symptoms of Dementia
Acceptance Commitment Therapy for Caregivers of People with Memory Loss
Family caregivers for persons with dementia report high levels of depression, stress, and burden. Caregivers' limited time, transportation constraints, and unpredictable schedules make on-line, self-guided interventions more…
- Conditions
- Caregiver Burden, Behavioral and Psychiatric Symptoms of Dementia, Depressive Symptoms, Quality of Life
- Trial name
- NCT05749939
- Testing
- Acceptance and Commitment Therapy
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Utah State University
COPD, Quality of Life
Psychological Distress in Patients With COPD
Chronic obstructive pulmonary disease (COPD) can significantly impact a person's quality of life, not only physically but also mentally.
- Conditions
- COPD, Quality of Life, Mental Health, Psychological Distress
- Trial name
- NCT06395311
- Testing
- COPD psychological well-being assessment
- Where
- Romania
- Volunteers
- 98 people
- Sponsor
- Spitalul Clinic de Boli Infecțioase și Pneumoftiziologie Dr. Victor Babeș Timișoara
PTSD, Sleep Disorder
Stepping Together for Children After Trauma, Norway
The goal of this randomized controlled trial is to learn about how to effectively help children (aged 7-12) who have developed moderate symptoms of posttraumatic stress after exposure to trauma, and prevent development of more…
- Conditions
- PTSD, Sleep Disorder, Depressive Symptoms, Quality of Life
- Trial name
- NorStep (NCT05734547)
- Testing
- Stepping Together for Children after Trauma (ST-CT), Usual care
- Where
- 2 sites in Norway
- Volunteers
- 160 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Cancer, Bone Marrow Neoplasms
The PRISM Intervention for Adolescents and Young Adults Receiving Hematopoietic Cell Transplantation
Multisite Randomized Controlled Trial (RCT) testing the efficacy of the Promoting Resilience in Stress Management (PRISM) intervention among Adolescents and Young Adults receiving hematopoietic cell transplantation for hematology…
- Conditions
- Cancer, Bone Marrow Neoplasms, Anxiety, Depression
- Trial name
- NCT03640325
- Testing
- PRISM (Promoting Resilience in Stress Management)
- Where
- 5 sites in United States
- Volunteers
- 143 people
- Sponsor
- Seattle Children's Hospital
Dementia, Depressive Symptoms
Effects of Integrated Exercise on Sarcopenia, Depression Symptoms, and Quality of Life
The goal of this quasi-experimental (nonrandomized intervention) study is to investigate the effects of an integrated exercise intervention on sarcopenia, depression symptoms, and quality of life in community-dwelling older…
- Conditions
- Dementia, Depressive Symptoms, Quality of Life (QOL), Sarcopenia in Elderly
- Trial name
- NCT06637228
- Testing
- Move Your Hands, Feet, and Brain: Integrated Exercise Intervention Based on Taipei City Elderly Physical Activity Guidelines
- Where
- 2 sites in Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung University of Science and Technology
Clinical Depression, Clinical Anxiety
Efficacy of Psychological Intervention for Children With Cancer
The study will be conductued at the Pediatric Oncology Department of the Children's Hospital, PIMS Islamabad, over the peroid of six months.
- Conditions
- Clinical Depression, Clinical Anxiety, Quality of Life
- Trial name
- NCT06620445
- Testing
- Interventiion or CBT Group
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Pakistan Institute of Medical Sciences