Clinical trials: Depression and Quality of Life
Primary Biliary Cirrhosis
Mind-body Wellness Intervention in Primary Biliary Cholangitis (PBC)
The investigators have designed a guided, online, multicomponent, mind-body intervention for participants with primary biliary cholangitis.
- Trial name
- NCT05374200
- Testing
- Mind-body intervention with 1-1 support from study personnel
- Where
- Canada
- Volunteers
- 87 people
- Sponsor
- University of Alberta
Caregiver Burden, Behavioral and Psychiatric Symptoms of Dementia
Acceptance Commitment Therapy for Caregivers of People with Memory Loss
Family caregivers for persons with dementia report high levels of depression, stress, and burden. Caregivers' limited time, transportation constraints, and unpredictable schedules make on-line, self-guided interventions more…
- Conditions
- Caregiver Burden, Behavioral and Psychiatric Symptoms of Dementia, Depressive Symptoms, Quality of Life
- Trial name
- NCT05749939
- Testing
- Acceptance and Commitment Therapy
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Utah State University
Fibromyalgia Syndrome, Fibromyalgia
Effects of 2-Aticyto Complex and D-Ribose on Pain and Clinical Course in Patients With Fibromyalgia
This multicenter, randomized, double-blind, placebo-controlled study will evaluate whether an oral supplement containing 2-Aticyto Complex and D-ribose (FibroThol), added to ongoing standard medical treatment, improves pain…
- Trial name
- NCT07495943
- Testing
- 2-Aticyto Complex and D-ribose Oral Supplement
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Acute Coronary Syndrome, Depressive Symptoms
Comparison of Depression Identification After Acute Coronary Syndrome: Quality of Life and Cost Outcomes
The purpose of this study is to examine, in a randomized controlled trial, the benefits and costs of the American Heart Association's (AHA) advisory for depression screen and treatment of post-acute coronary syndrome patients.
- Trial name
- CODIACSQoL (NCT01993017)
- Testing
- Cognitive Behavioral Therapy (CBT), Antidepressant Medication, Standard Care
- Where
- 4 sites in United States
- Volunteers
- 1,501 people
- Sponsor
- Columbia University
Mental Health, Physical Health
Parental Well-being After Childbirth in Switzerland
Improving maternal and child health is a global priority, with increasing emphasis on ensuring women and their families not only survive but also thrive after childbirth.
- Conditions
- Mental Health, Physical Health, Postpartum, Parents
- Trial name
- SOCRATES (NCT06886841)
- Where
- 2 sites in Switzerland
- Volunteers
- 4,200 people
- Sponsor
- Laurent Gaucher
Depression Chronic, Depression and Quality of Life
Remote Medical Monitoring of Patients With Depression
The goal of this clinical trial is to learn if ThIA Suivi, a digital tool for remote monitoring of patients, can improve the care of adults with depression who are followed by a psychiatrist.
- Conditions
- Depression Chronic, Depression and Quality of Life, Depression, Major Depressive Episode
- Trial name
- TELEMED-DEP (NCT07878754)
- Testing
- Use of ThIA Medical Device
- Where
- 3 sites in France
- Volunteers
- 608 people
- Sponsor
- ThIA Santé Mentale
Intervention, Control
A Sleep Intervention for Cancer Patients and Their Caregivers
The purpose of the study is to design and test a dyadic sleep intervention for patients diagnosed with cancer and their intimate partner.
- Trial name
- NCT04969146
- Testing
- Dyadic Intervention, Patient Only Intervention
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Type 1 Diabetes Mellitus
Resistance Training on Depression and Quality of Life in Type 1 Diabetic Women
Find out the effects of resistance training on depression, sleep quality, and quality of life in women with type 1 diabetes mellitus
- Trial name
- NCT07466186
- Testing
- Resistance exercises, Breathing exercises
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Middle East University
Quality of Life, Behavioral Symptoms
A Structured Qi-gong Program for Hospitalized Older Adults
The purpose of this study is to test the effects on a number of health outcomes and the feasibility of a structured program of qi-gong, a form of tai-chi which has been previously tested in older populations, in older…
- Conditions
- Quality of Life, Behavioral Symptoms, Patient Compliance
- Trial name
- NCT00944788
- Testing
- qi-gong
- Where
- Spain
- Volunteers
- 58 people
- Sponsor
- Fundacio Salut i Envelliment UAB
Depression
The Effect of Duloxetine on Mood, Quality of Life and Cognitive Functioning in Glioblastoma Patients
Primary tumor glioblastoma is the most common malignant brain. Standard treatment includes biopsy or excision of the tumor in order to obtain a pathological diagnosis, and tumor mass reduction.
- Trial name
- NCT02443194
- Testing
- duloxetine
- Volunteers
- 50 people
- Sponsor
- michal roll
Older Adults, Hearing Impairment
Effect of an Aural Rehabilitation Program in Hearing-impaired Older Adults
Hearing impairment in older adults is becoming a common health problem as the population ages. The impact of hearing impairment in older adults includes not only physical function and cognitive performance, but also depression…
- Conditions
- Older Adults, Hearing Impairment, Nursing
- Trial name
- NCT05083221
- Testing
- Hear-Talk-Activity audiological program
- Where
- Taiwan
- Volunteers
- 96 people
- Sponsor
- National Taiwan University Hospital
Stress, Anxiety
Medical Yoga for Patients With Stress-related Symptoms and Diagnoses
Background An increasing number of patients are suffering from stress-related symptoms and diseases. No scientific studies have examined the effects of Medical yoga on stress-related symptoms in patients in primary care.
- Conditions
- Stress, Anxiety, Depression
- Trial name
- NCT01604707
- Testing
- Medical Yoga
- Volunteers
- 44 people
- Sponsor
- Region Örebro County
Cardiac Arrest (CA)
Effects of a Web-based Support Programme for Cardiac Arrest Survivors
The overall goal of this clinical trial is to learn if a web-based support programme can improve wellbeing in cardiac arrest survivors by helping them manage emotional, cognitive, and physical challenges.
- Trial name
- CARDIS (NCT07240714)
- Testing
- Digital Support Programme
- Where
- 9 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Linkoeping University
Anxiety, Depression
Improving Patient and Family Centered Care in Advanced Critical Illness
One in five deaths in the U.S. occurs in or shortly after discharge from an intensive care unit (ICU), typically following decisions made by surrogate decision makers to forego life prolonging treatment.
- Trial name
- PARTNER (NCT01844492)
- Testing
- The PARTNER Intervention, ICU Usual Care Control
- Where
- United States
- Volunteers
- 1,420 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Chronic Heart Failure (CHF), Anxiety and Depression
Depression and Quality of Life in Chronic Heart Failure Patients and the Caregivers
Anxiety and depression are often present in patients with chronic heart failure (CHF). This study aimed to evaluate the influence of anxiety and depression on the physical function, disability, and quality of life (QOL) in CHF.
- Conditions
- Chronic Heart Failure (CHF), Anxiety and Depression, Quality of Life (QOL), Exercise
- Trial name
- NCT01197313
- Testing
- Home-based exercise
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- National Taiwan University Hospital
Multimorbidity, Hypertension
Development and Validation of a Comprehensive Management Service Package for Older Adults With Multimorbidity
This study aims to test a new comprehensive management service package for older adults with two or more chronic conditions (multimorbidity).
- Conditions
- Multimorbidity, Hypertension, Diabetes Mellitus, Coronary Artery Disease
- Trial name
- COMPASS (NCT07151430)
- Testing
- Service Package Group
- Volunteers
- 358 people
- Sponsor
- Xuanwu Hospital, Beijing
Neuropathic Pain
The Effect of Neuropathic Pain in Patients With Combat-related Extremity Injury
It has been suggested that veterans with chronic pain might be at increased risk for the development of depression, anxiety and post-traumatic stress disorder.
- Trial name
- NCT04674631
- Testing
- The effect of neuropathic pain on quality of life, depression and sleep quality
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Chronic Urticaria
Quality of Life in Patients With Chronic Urticaria
Urticaria is one of the most frequent presenting complaints in dermatology, allergy, and emergency departments. The term chronic urticaria (CU) is understood as the appearance of recurrent wheals more than twice a week for over 6…
- Trial name
- NCT03163875
- Testing
- Hospital Anxiety and Depression Scale
- Volunteers
- 30 people
- Sponsor
- Assiut University
Heart Failure, Cardiac Failure
Heart Failure Insomnia Treatment Study
The purpose of this study is to compare a short, behavioral treatment for insomnia with sleep monitoring to determine whether these approaches are effective in reducing insomnia and improving sleep quality among patients with…
- Conditions
- Heart Failure, Cardiac Failure, Congestive Heart Failure, Insomnia
- Trial name
- H-FITS (NCT03636880)
- Testing
- Brief treatment for Insomnia, Sleep Monitoring
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Ohio State University
Depressive Symptoms, Quality of Life
Non-pharmacological Care for Depression in Cancer Patients Using VR and TMS
Despite its significant impact on individuals and healthcare systems, substantial gaps remain in the clinical and rehabilitative management of depression in oncology patients.
- Conditions
- Depressive Symptoms, Quality of Life, Cognitive Impairment
- Trial name
- INCEPT (NCT06589544)
- Testing
- Virtual Reality-based Cognitive Remediation (VR-COG) + Treatment as Usual (TAU), Repetitive transcranial magnetic stimulation (rTMS) + Treatment as usual (TAU), Treatment as Usual (TAU)
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University Hospital of Ferrara