Clinical trials: Depressive, Symptoms Depressive Disorder, Depression
Depressive Symptoms
EMA Baseline Screening System for Therapists Who Treat Youths With Depressive Symptoms
Youth depression is a matter of concern worldwide. It affects an important part of the young population around the world and its consequences both physically and mentally make this issue an important research field for…
- Trial name
- NCT04830527
- Testing
- EMA prompting for patients, PDF Reports for therapists
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Vania Martínez-Nahuel
Depression
Culturally Sensitive Collaborative Treatment for Depressed Chinese Americans
This study will evaluate the effectiveness of culturally sensitive treatment versus regular care in treating depressed Chinese Americans.
- Trial name
- NCT00227929
- Testing
- Care Management
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Depression - Major Depressive Disorder, Transcranial Magnetic Stimulation
Effects of Low-intensity Transcranial Magnetic Stimulation on Major Depressive Disorder, and on 5-hydroxyindoleacetic Acid and Brain-derived Neurotrophic Factor Levels
The goal of this randomised clinical trial is to evaluate the effects of transcranial magnetic stimulation (TMS) on major depressive disorder (MDD) and on the levels of 5-hydroxyindoleacetic acid (5-HIAA) and brain-derived…
- Conditions
- Depression - Major Depressive Disorder, Transcranial Magnetic Stimulation, Placebo
- Trial name
- NCT06667180
- Testing
- Low-intensity TMS
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Universidad de Guanajuato
Depressive Disorder
M3VAS Validation in Polish Population
Low mood and anhedonia represent the fundamental symptoms of major depressive disorder (MDD). Nevertheless, there is currently no standardized visual analogue scale available to assess the extent of both symptoms concurrently.
- Trial name
- NCT06412562
- Testing
- The Maudsley 3-item Visual Analogue Scale (M3VAS)
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Gdansk
Alzheimer Disease, Depression
Transcranial Direct Current Stimulation for Depression in Alzheimer's Disease Patient - Preliminary Research
This project will investigate the safety and efficacy of transcranial direct current stimulation (tDCS) in the treatment of depression among patients with Alzheimer's disease.
- Trial name
- ADAPT (NCT02351388)
- Testing
- Transcranial Direct Current Stimulation
- Where
- Japan
- Volunteers
- 4 people
- Sponsor
- National Center of Neurology and Psychiatry, Japan
Depression
Pharmacogenetic Testing in an Outpatient Population of Patients With Depression
This is a randomized, control group design of pharmacogenetic implementation in a mental health population of subjects taking anti-depressants and/or anti-psychotics with a new or current primary or secondary diagnosis of Major…
- Trial name
- PGx-UPA (NCT02497027)
- Testing
- pharmacogenetic testing
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Avera McKennan Hospital & University Health Center
Depressive Disorder, Emotional Dysregulation
Music Therapy for Adolescents with Emotional Difficulties
The goal of this clinical trial is to examine the effects of a music therapy program in adolescents aged 13-18 years old with emotional difficulties, primarily depression and possibly concurrent diagnoses of anxiety.
- Trial name
- NCT06733883
- Testing
- psychotherapy
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Major Depressive Disorder
Multi-site Feasibility of an Integrated Treatment for the Biology and Experience of Depression: The MULTIBED Study
This randomized 2x2 factorial intervention trial administers 8 weekly cognitive behavioral therapy (CBT) sessions (yes/no) and 4 bi-weekly active whole-body hyperthermia (WBH) sessions (yes/no) to adults aged 18 years or older…
- Trial name
- NCT07596914
- Testing
- Cognitive Behavioral Therapy (CBT), Whole-Body Hyperthermia
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Depression
Identification and Therapy of Postpartum Depression
This study will evaluate the effectiveness of a telephone-based depression screening and care management program in treating depression in postpartum women.
- Trial name
- NCT00282776
- Testing
- Care Management for Postpartum Depression, TAU
- Where
- United States
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Major Depressive Disorder, Major Depressive Episode
Glabellar Botulinum Toxin Injections for the Treatment of Geriatric Depression
The effectiveness of glabellar injection of botulinum toxin type A (BTA) in treating depression has not yet been investigated in elderly patients.
- Conditions
- Major Depressive Disorder, Major Depressive Episode, Treatment Resistant Depression
- Trial name
- BOTDEP (NCT03833063)
- Testing
- botulinum toxin A
- Sponsor
- Helse Stavanger HF
Depressive Episode
Characterisation of Fundamental Decision Making in People Suffering From a Characterised Depressive Episode
The investigators will include patients suffering from Major Depressive Disorder (MDD), in episode. The patients will undertake neuropsychological tasks evaluating executive function and clinical assessment related to depressive…
- Trial name
- MINDDE (NCT05654948)
- Testing
- computerised cognitive performance test : MindPulse
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Tours
Major Depression
The Effect of Exercise on Depressive Symptoms in Unmedicated Patients
This trial investigates the biological effect of exercise training on depression. Participants will randomly be allocated to either a aerobic exercise group performing exercise on stationary bikes or a group performing low-impact…
- Trial name
- DEMOII (NCT00695552)
- Testing
- Aerobic exercise, Low impact exercise
- Where
- Denmark
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Major Depression
Bilateral Versus Monolateral Repetitive Transcranial Stimulation in Depression
Repetitive transcranial magnetic stimulation (rTMS) has been recently FDA approved for the treatment of resistant depression. No accordance exists on which are the involved mechanisms of action and on which stimulation…
- Trial name
- NCT00806143
- Testing
- repetitive transcranial stimulation (rTMS), unilateral stimulation
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Institute of Neuroscience, Florence, Italy
Major Depressive Disorder
Neural Components Underlying the Treatment of Adolescent Depression
The goal of the study is to examine how cognitive behavioral therapy (CBT), a common treatment for adolescent depression, affects brain functioning.
- Trial name
- NCT01717508
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Depressive Symptoms, Anxiety Symptoms
Culturally Adapted i-CBT for Farsi/Dari Speaking Migrants
The aim of this randomized controlled trial (RCT) is to investigate the effectiveness of a culturally adapted internet-based cognitive behavioral therapy (i-CBT) intervention in reducing symptoms of common mental health issues…
- Conditions
- Depressive Symptoms, Anxiety Symptoms, Grief, Psychological Trauma
- Trial name
- i-CBT (NCT06828276)
- Testing
- Culturally adapted i-CBT
- Where
- Sweden
- Volunteers
- 93 people
- Sponsor
- Karolinska Institutet
Depression, Major Depressive Disorder
Study of Naltrexone-Induced Blockade of Antidepressant Effects
The goal of this study is to determine whether antidepressant placebo effects and contextual cues broadly, can be blocked by one single dose of the µ-opioid antagonist naltrexone.
- Trial name
- SONRISA2 (NCT04322526)
- Testing
- Naltrexone 50 Mg Oral Tablet
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Marta Peciña, MD PhD
Depressive Symptoms, Generalized Anxiety, or Psychological Stress
Mobile Intervention for Mental Health of Family Caregivers in Thailand
The primary objective of this study is to evaluate the effectiveness of the CAMMA intervention in reducing psychological distress among family caregivers of adults with chronic conditions in Thailand.
- Trial name
- NCT06722287
- Testing
- Caregiver Mental Health Mobile Application (CAMMA) Intervention, Usual Care Group
- Where
- Thailand
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Depressive Symptoms, Depression
Goal2QuitVaping for Nicotine Vaping Cessation Among Adolescents
The purpose of this study is to evaluate a mobile application (app) called "Goal2QuitVaping" to help adolescents quit vaping nicotine. Goal2QuitVaping was developed by our research team to assist with quitting vaping.
- Conditions
- Depressive Symptoms, Depression, Adolescent Behavior
- Trial name
- NCT04951193
- Testing
- Behavioral Activation Therapy app, Treatment as Usual
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Post-partum Depression
Virtual Patient Navigation During a Pandemic
The sub-study will involve a rigorous mixed-methods design. The qualitative phase of the sub-study will consist of semi-structured interviews.
- Trial name
- NCT06208852
- Testing
- Virtual Navigator Program
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Depression, Neurofeedback
Neurofeedback In Treatment Resistant Depression
The investigators evaluate the effects of neurofeedback as an augmentation treatment on depressive symptoms and functional recovery in patients with treatment-resistant depression (TRD).
- Trial name
- NCT04078438
- Testing
- neurofeedback augmentation, treatment as usual
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Yeungnam University Hospital
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