Clinical trials: Depressive, Symptoms Depressive Disorder, Depression
Multiple Sclerosis, Anxiety
The Effect of Emotional Freedom Technique on Depression, Anxiety and Distress of Individuals With Multiple Sclerosis
Volunteers over the age of 18 who applied to the Neurology Outpatient Clinic of Dokuz Eylül University Hospital, who were diagnosed with multiple sclerosis in the last three months, one month after the initiation of treatment and…
- Conditions
- Multiple Sclerosis, Anxiety, Depressive Symptoms, Psychiatric Nursing
- Trial name
- NCT04969562
- Testing
- Emotional Freedom Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Dokuz Eylul University
Bereavement, Depressive Disorder
Consequences of Conjugal Bereavement in Adults
Bereavement refers to the expected reactions and sadness associated with the loss of a loved one. It has been reported that the loss of a spouse is rated as the major life stressor among survivors of varying ages and diverse…
- Conditions
- Bereavement, Depressive Disorder, Immunologic Disease, Mental Disorder
- Trial name
- NCT00001659
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Depressive Symptoms, Cognitive Symptom
JAK Signaling in Depression and Cognition in Male Football Players
This study is being done to learn more about the role of inflammation in depressive and cognitive symptoms in patients with depression who have played at least 11 years of organized tackle football.
- Trial name
- JAK DC in Play (NCT07608796)
- Testing
- Baricitinib
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Emory University
Depression
Does Fish Oil Prevent Depression in Pregnancy and Postpartum?
This study is designed to test whether an alternative medicine treatment, fish oil, will prevent depressive symptoms in pregnant and postpartum women who have been found to be at risk for depression.
- Trial name
- NCT00711971
- Testing
- EPA-rich fish oil supplement, DHA-rich fish oil supplement
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Schizophrenia, Major Depressive Disorder
Effectiveness of Traditional Chinese Metacognitive Training (MCT) in Patients With Schizophrenia, Depression, or Bipolar Disorder Attending a Psychiatric Day Hospital in Taiwan
Schizophrenia is characterized by positive symptoms such as delusions and hallucinations, which significantly impact daily functioning.
- Conditions
- Schizophrenia, Major Depressive Disorder, Bipolar Disorder
- Trial name
- NCT07051746
- Testing
- Metacognitive Training (MCT), Traditional Chinese version
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- ZI-YU LIN
Major Depressive Disorder, MDD
tDCS: Sleep to Mood in Depression (S2M-D)
The purpose of this study is to determine whether changes in sleep consolidation occur during home-based transcranial direct current stimulation (tDCS) in adults with moderate depression and whether these changes are temporally…
- Conditions
- Major Depressive Disorder, MDD, Depression, Major Depressive Episode
- Trial name
- NCT07572526
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- NYU Langone Health
Depressive Disorder, Major
Paroxetine-referenced Study Evaluating Three Doses of DVS SR in Outpatients With MDD
This study will assess the safety, tolerability and efficacy of desvenlafaxine succinate sustained release (DVS SR) in subjects with major depressive disorder.
- Trial name
- NCT00445679
- Testing
- DVS SR, Paroxetine
- Where
- 43 sites in China, India and 2 more
- Volunteers
- 807 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Anxiety Symptoms, Screen Time
Effects of Digital Detox on Mental Health in Young Adults
The goal of this clinical trial is to learn whether a short, self-guided program for cutting down smartphone screen time can reduce symptoms of depression in young adults.
- Conditions
- Anxiety Symptoms, Screen Time, Depressive Symptoms
- Trial name
- NCT07827703
- Testing
- App-based smartphone screen time restriction program
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- University of Bergen
Major Depressive Disorder
Imaging Dopamine Release in Depression
This study aims to determine whether ventral striatal dopamine release is a mechanism of reward motivation in major depression, whether dopamine release is low in depression, and whether DA release and reward motivation predict…
- Trial name
- NCT02033369
- Testing
- Pramipexole
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Mental Health Care, Mental Disorders
Using Responsible Artificial Intelligence (AI) to Predict Online Therapy Outcome and Engagement
This study is to develop AI-based models for the personalised prediction of treatment engagement and treatment outcomes in patients engaging in digital psychotherapy.
- Trial name
- NCT05758285
- Testing
- AI-Based Prediction of Treatment Engagement and Outcomes
- Where
- Switzerland
- Volunteers
- 6,671 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Depression
Genetics of Recurrent Early Onset Major Depression
This study will identify specific genes that may cause a predisposition to depression in some families.
- Trial name
- NCT00260182
- Where
- 6 sites in United States
- Volunteers
- 2,302 people, healthy volunteers welcome
- Sponsor
- Stanford University
Borderline Personality Disorder
Selective Serotonin Reuptake Inhibitors (SSRIs) in Borderline Personality Disorder
The goal of this study is to examine the effectiveness the selective serotonin reuptake inhibitor (SSRI) escitalopram (also known by the trade name "Lexapro") in reducing desire to self-harm and actual self-harming among young…
- Trial name
- NCT01103180
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Chicago
Depressive Disorders, Anxiety Disorders
Study on a Digital Ultra-Brief Intervention During Wait Times for Psychotherapy
The OPTIBRIEF study investigates different versions of a digital ultra-brief intervention (UKADO - a German acronym for ultra-brief intervention against anxiety and depression online) during the waiting period for psychotherapy.
- Trial name
- OPTIBRIEF (NCT07167849)
- Testing
- UKADO Content - problem-focused, UKADO Content - resource-focused, Human support
- Where
- Switzerland
- Volunteers
- 312 people
- Sponsor
- University of Bern
Ketamine; Depressive Symptom; Neurosurgery; Perioperative Period
Ketamine and Postoperative Depressive Symptom-PASSION
Perioperative depression symptom (PDS) is one of the common mental comorbidity, and influences the clinical outcomes and prognosis. However, there is no rapid acting treatment to deal with it during the limited hospital stay.
- Trial name
- NCT03086148
- Testing
- Ketamine, Normal saline
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Beijing Tiantan Hospital
Emotional Problem, Anxiety
A Transdiagnostic Internet Intervention for Parents of Children With Anxiety and Depressive Symptoms
The purpose of this study is to evaluate the efficacy of a transdiagnostic, parent-led, Internet-delivered intervention in reducing child and adolescent internalizing problems.
- Conditions
- Emotional Problem, Anxiety, Depression, Psychological Distress
- Trial name
- ParentKIT (NCT05341297)
- Testing
- ParentKIT
- Where
- Romania
- Volunteers
- 111 people
- Sponsor
- Babes-Bolyai University
Depression
Pipamperone/Citalopram (PipCit)Versus Citalopram in the Treatment of Major Depressive Disorder(MDD)
The primary objective is to demonstrate whether the addition of pipamperone 5 mg twice daily (bd) to citalopram, 40 mg daily in patients suffering from MDD will improve the efficacy of citalopram 40 mg in these patients.
- Trial name
- NCT00672659
- Testing
- Citalopram + Pipamperone, Citalopram
- Where
- United Kingdom
- Volunteers
- 165 people
- Sponsor
- PharmaNeuroBoost N.V.
Burnout Syndrome, Anxiety Depression
Prevention of Burnout in Spanish Healthcare Professionals Through Attachment-Based Compassion Therapy (ABCT)
Burnout is a common problem among healthcare professionals and may affect their psychological well-being, quality of life, and professional functioning.
- Conditions
- Burnout Syndrome, Anxiety Depression, Stress
- Trial name
- NCT07698379
- Testing
- Attachment-based compassion therapy Compassion, Relaxation program
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Hospital Miguel Servet
Folate Deficiency, Vitamin B 12 Deficiency
Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage Girls
Folic acid and vitamin B12 play an interdependent role in key cellular processes, namely deoxyribonucleic acid synthesis, cell division, red blood cell formation, and nervous system myelination.
- Conditions
- Folate Deficiency, Vitamin B 12 Deficiency, Anemia, Megaloblastic, Cognitive Development
- Trial name
- NCT06100146
- Testing
- Folic acid and vitamin B12 fortified flour, Unfortified cereal flour
- Where
- 2 sites in Ethiopia
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- University Ghent
Major Depressive Disorder
Integral Assessment in Unipolar Depression
The objective of this project is to assess the occurrence of early improvement within the first two weeks of antidepressant treatment and to correlate this improvement with favorable therapeutic outcome at the end of the acute…
- Trial name
- AIUNI (NCT02268487)
- Testing
- Sertraline
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo
Stroke, Acute, Expressive Aphasia
Music After Stroke To Enhance Rehabilitation
Music that is familiar and preferred by patients has been shown to heighten neuroplasticity and can mitigate these disabilities.
- Conditions
- Stroke, Acute, Expressive Aphasia, Movement, Abnormal, Depressive Disorder
- Trial name
- MASTER (NCT04441515)
- Testing
- Ipod with music, ipod with books to listen, ipod only with usual care
- Volunteers
- 12 people
- Sponsor
- Pace University
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