Clinical trials: Depressive; Behavioral Disorder
Major Depressive Disorder, Therapy Resistant Depression
Add-on Therapy With Edupression.Com® on Therapy Resistant Depressive Patients Treated With Nasal Esketamine Spray
Pragmatic clinical trial of an add-on therapy regarding the use of edupression.com® - a licensed computer based self-help program - on patients with therapy-resistant depression receiving esketamine nasal spray
- Trial name
- Esketamin+ (NCT04843462)
- Testing
- edupression.com®, Esketamine nasal spray
- Where
- Austria
- Volunteers
- 70 people
- Sponsor
- Lukas Pezawas
Major Depressive Disorder
Repetitive Transcranial Magnetic Stimulation for Treating Depression: A Functional Magnetic Resonance Imaging Study
This protocol, "Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Major Depressive Disorder (MDD): A Functional Connectivity Magnetic Resonance Imaging (fcMRI) Study," is an open-label pilot treatment…
- Trial name
- NCT01162382
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Washington University School of Medicine
Depressive Disorder, Pregnancy
EnBrace HR for Depression Treatment and Prevention in Women Trying to Conceive and Early Pregnancy
The purpose of this study is to assess the effectiveness of the EnBrace HR prenatal supplement in preventing depression in women with a history of depression who have decided to stop taking antidepressants during their pregnancy…
- Trial name
- NCT02676882
- Testing
- EnBrace HR
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Post-partum Depression
Treatment of Post-partum Depression Using an Behavioral Intervention Called ROSE (Reach Out, Stay Strong, Essentials for Mothers of Newborns) Delivered Using an Electronic App
A randomized trial of pregnant people at risk for postpartum depression comparing the InBloom app (n = 76) to ROSE (n = 76; weekly scheduled group), and two control groups.
- Trial name
- NCT05518162
- Testing
- InBloom, ROSE
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- University of Rochester
Depressive Disorder, Depressive Symptoms
Effectiveness of Traditional and Computerized Versions of Super Skills for Life in Children
Super Skills for Life (SSL) is a transdiagnostic cognitive-behavioral protocol developed for children aged 6 to 12 with anxiety and comorbid problems (e.g., depression, low self-esteem, and lack of social skills).
- Conditions
- Depressive Disorder, Depressive Symptoms, Anxiety Disorders, Anxiety Disorders and Symptoms
- Trial name
- NCT05574491
- Testing
- Super Skills for Life: traditional version, Super Skills for Life: computerized version
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Major Depressive Disorder
A Remote Electronically Delivered Integrated Care Pathway: A Feasibility Study
This is a one-armed observational study and feasibility trial of a remote electronically-delivered integrated care pathway for the treatment of adolescents.
- Trial name
- eCARIBOU (NCT05086120)
- Testing
- eCARIBOU
- Where
- 2 sites in Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Major Depressive Disorders
Efficacy and Safety of One Single Dose of SR58611 Compared to Placebo and Paroxetine
Primary objective is to demonstrate the antidepressant efficacy on the Hamilton depression rating scale (HAM-D) of amibegron (SR58611) 700 mg/day compared to placebo in the treatment of patients with a recurrent major depressive…
- Trial name
- NCT00825019
- Testing
- amibegron (SR58611A), paroxetine
- Where
- United States
- Volunteers
- 306 people
- Sponsor
- Sanofi
Major Depressive Disorder (MDD)
Group Acceptance and Commitment Therapy (ACT) Among Depressive Patients in Kelantan, Malaysia
The goal of this clinical trial is to learn if group acceptance and commitment therapy works to improve depressive symptoms, psychological flexibility and quality of life in adults. The main questions it aims to answer are: 1.
- Trial name
- Group ACT (NCT06710912)
- Testing
- Group acceptance and commitment therapy (ACT), Treatment as usual
- Where
- Malaysia
- Volunteers
- 44 people
- Sponsor
- Universiti Sains Malaysia
Mood Disorder, Bipolar Disorder
Examination of Brain Serotonin Receptors in Patients With Mood Disorders
The purpose of this study is to evaluate the function of certain brain chemicals and receptors in patients with mood disorders. This study will also examine how the stress hormone cortisol affects brain function.
- Conditions
- Mood Disorder, Bipolar Disorder, Depression
- Trial name
- NCT00026832
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- National Institute of Mental Health (NIMH)
Major Depressive Episode, Bipolar Depression
NeoSync TMS Treatment for Bipolar I Depression
This study is designed to evaluate the safety and preliminary efficacy of synchronized transcranial magnetic stimulation (sTMS) using the NeoSync EEG Synchronized TMS device (NEST) in subjects with Bipolar Disorder type I in a…
- Conditions
- Major Depressive Episode, Bipolar Depression, Bipolar Disorder, Mood Disorders
- Trial name
- NESTTBID (NCT02839798)
- Testing
- NEST (NeoSync EEG Synchronized TMS)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Butler Hospital
Depressive Symptoms
Automated and Personalized Cognitive Behavioral Therapy
This study is designed to evaluate a novel online tool to deliver computerized Cognitive Behavioral Therapy (CBT). Participants will be randomized into three groups: experimental, active control, and waitlist.
- Trial name
- NCT03445598
- Testing
- Interactive and personalized CCBT, Feature-limited CCBT, Waitlist control
- Where
- India
- Volunteers
- 600 people
- Sponsor
- Indian Institute of Technology Kanpur
Major Depressive Disorder
An Eight-week Study of SSR411298 as Treatment for Major Depressive Disorder in Elderly Patients
The primary objective of this study is to evaluate the efficacy of 3 fixed doses of SSR411298 (10, 50 or 200 mg daily) compared to placebo, in elderly patients with Major Depressive Disorder (MDD), based on the 17-item Hamilton…
- Trial name
- FIDELIO (NCT00822744)
- Testing
- SSR411298, Escitalopram
- Where
- 7 sites in Chile, Mexico and 5 more
- Volunteers
- 527 people
- Sponsor
- Sanofi
Spinal Cord Injury, Depression - Major Depressive Disorder
Intermittent Fasting for Inflammation and Depression in Spinal Cord Injury
Depression and chronic inflammation are common problems for people with spinal cord injury (SCI). Inflammation has been shown to influence depression which may make it an important treatment target.
- Trial name
- NCT06807528
- Testing
- Intermittent fasting, Behavioral Support Strategies
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Parenting, Breastfeeding
Doula Support for Young Mothers: A Randomized Trial
The goal of this study was to evaluate the impact of a doula home visiting intervention on young, low-income mothers' birth outcomes, breastfeeding, postpartum depressive symptoms, and parenting, and on their children's…
- Conditions
- Parenting, Breastfeeding, Depression, Postpartum
- Trial name
- NCT01925664
- Testing
- Doula
- Where
- United States
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Depressive Disorder, Major
Alpha-Stim AID and Major Depressive Disorder
The study will be a multi-centre parallel group, double blind, non-commercial, randomised controlled superiority trial. Study participants will be referred from Primary Care GP practices via their GP and randomised into active…
- Trial name
- NCT04963907
- Testing
- Active Alpha-Stim CES
- Where
- United Kingdom
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Electromedical Products International, Inc.
Stress Disorders, Post-Traumatic, Depressive Symptoms
Mindfulness-based Intervention to Address PTSD in Trauma-exposed, Homeless Women
Posttraumatic stress disorder (PTSD) is a major public health concern that disproportionately effects minorities and those with low-socioeconomic status, such as homeless women, creating a critical health disparity.
- Conditions
- Stress Disorders, Post-Traumatic, Depressive Symptoms, Hydrocortisone, Substance Use
- Trial name
- NCT04605198
- Testing
- Modified Mindfulness-based Stress Reduction, Health Promotion Wellness Classes
- Where
- 2 sites in United States
- Volunteers
- 156 people
- Sponsor
- University of California, Los Angeles
Stress, Psychological, Stress, Physiological
Family-centered Mental Health Promotion Intervention
Goal: The long-term goal of the proposed research program is to test the effectiveness of a preventative behavioral intervention and to scale it up for use with broader immigrant populations to reduce stress and mental health…
- Conditions
- Stress, Psychological, Stress, Physiological, Anxiety, Depression
- Trial name
- NCT04453709
- Testing
- Problem Management Plus for Immigrants at family settings, Talk program with Community Support Service Pamphlet (CSS)
- Where
- United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Major Depressive Disorder, Generalized Anxiety Disorder
Mental Health Assessment and Prescribing by Alberta Pharmacists
This is a clinical trial evaluating the experimental intervention of enhanced pharmacist care by pharmacists with additional prescribing authorization (APA) in Alberta, for patients newly diagnosed with Major Depressive Disorder…
- Conditions
- Major Depressive Disorder, Generalized Anxiety Disorder, Pharmacist-Patient Relations
- Trial name
- MAP-AP (NCT04410575)
- Testing
- Standard Pharmacist Care, Reviewed Questionnaire tool results with participant, Patient Clinical Assessment
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Anxiety Disorders, Depressive Disorder
Flourishing and Virtue in Cognitive-Behavioral Therapy for Anxiety and Depressive Disorders
This two phase study is testing an online version of a transdiagnostic, cognitive behavioral therapy, against a modified version of that therapy emphasizing positive affect.
- Trial name
- NCT05120232
- Testing
- Unified Protocol, Modified Unified Protocol (UP+)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Boston University Charles River Campus
Chronic Pain, Depression
Clinical Efficacy and Immune Effects of Acupuncture in Patients With Comorbid Chronic Pain and Major Depression Disorder
Background: Depression and pain are highly comorbid and share biological mechanisms. Acupuncture is commonly used to manage both pain and depression, but the choice of acupoints for specific disorders differs.
- Trial name
- NCT03328819
- Testing
- Acupuncture
- Where
- Taiwan
- Volunteers
- 75 people
- Sponsor
- China Medical University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.