Clinical trials: Depressive Disorder
Mental Illness, Depression
Identifying Parents in Child Welfare Services Who Need Mental Health Support: Depression and Anxiety Symptoms
The main aim of this study is to examine the occurrence of mental health symptoms among parents referred to the Swedish child welfare services for child maltreatment and other family related risks.
- Conditions
- Mental Illness, Depression, Anxiety
- Trial name
- NCT06572865
- Testing
- Screening for depression and anxiety
- Where
- Sweden
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Social Activity
Oxytocin and Social Behavior Over the Lifespan
This study will investigate if intranasal oxytocin (a hormone naturally produced in the body) promotes motivation for, and engagement in, social activities in older adults.
- Trial name
- NCT00914953
- Testing
- oxytocin (Pitocin)
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Claremont Graduate University
Cross Sectional Hospital Based Study
Risk Perception Associated With Covid-19 Among Anesthetists
Since the outbreak of the COVID-19 pandemic, the anesthesiologists are involved in the riskiest interventions e.g. airway management, endotracheal intubation, and resuscitation.
- Trial name
- NCT04861272
- Testing
- Survey
- Where
- Saudi Arabia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- King Saud University
Sleep Disturbance, Sleep Problems
Transdiagnostic Sleep Intervention to Improve Mental Health in Adolescents
This cluster randomized controlled trial will evaluate whether a brief, school-based group adaptation of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) improves sleep and mental health in…
- Conditions
- Sleep Disturbance, Sleep Problems, Substance Use (Drugs, Alcohol), Anxiety
- Trial name
- SLEEP-TEEN (NCT07865728)
- Testing
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction, Healthy habits psychoeducation
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
Depression
Village-based Intervention for Late-life Depression
Investigators aimed to examine the feasibility and effectiveness of a village-based multilevel intervention for late-life depression.
- Trial name
- NCT04013165
- Testing
- Active control, Village-based intervention
- Where
- South Korea
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Elderly, Exercise
Tai Chi Exercise and Receptive Music Therapy for the Elderly
Frailty has become a major public health issue with the global aging population. In general, severe physical impairments and accompanying frailty in older adults are associated with adverse clinical outcomes.
- Conditions
- Elderly, Exercise, Therapy
- Trial name
- NCT06413407
- Testing
- Tai Chi Exercise, Receptive Music Therapy, Experimental
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Memory Dysfunction, Anxiety
Effects of Orally Administered Thymus Vulgaris Leaves on Memory, Anxiety, Depression, and Sleep Quality in University Students: A Randomized Controlled Trial
Thymus vulgaris could potentially serve as a safer alternative to stimulant drugs for enhancing memory among university students.
- Conditions
- Memory Dysfunction, Anxiety, Depression, Sleep
- Trial name
- NCT05987228
- Testing
- Thymus vulgaris
- Where
- Jordan
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- The Hashemite University
Mental Health, Depression
rTMS for Emotional Difficulties in Verterans
Mental illness rarely occurs as a single, easily categorized condition. Instead, multiple disorders often co-occur. This complicates the treatment plan for many Veterans, especially those suffering the most severe dysfunction.
- Conditions
- Mental Health, Depression, rTMS, Anxiety
- Trial name
- rTMS (NCT03749967)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Healthy Participants, Anxiety Disorders (With High Anxiety Symptoms)
tVNS and Approach-Avoidance Behavior in Anhedonia and Anxiety
This study investigates if anhedonia and anxiety symptoms are associated with alterations in reinforcement learning, effort trade-offs for wins vs. punishments, and foraging behavior under threat.
- Conditions
- Healthy Participants, Anxiety Disorders (With High Anxiety Symptoms), Depressive Disorders (With High Anhedonia Symptoms), Comorbid Depression and Anxiety Disorder (With High Anhedonia and High Anxiety Symptoms)
- Trial name
- NCT07476469
- Testing
- tVNS
- Where
- Germany
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Dr. Nils B. Kroemer
Recreational Drug Use, Sexual Violence
Evaluation of Teen Connection Project for Trans and Gender Minority Youth
The purpose of this project is to develop and evaluate an online mentoring and skill-building program for transgender and/or gender minority youth (TGMY) ages 14 to 18, the Teen Connection Project (TCP).
- Conditions
- Recreational Drug Use, Sexual Violence, Victimisation, Depressive Symptoms
- Trial name
- TCP (NCT06587139)
- Testing
- Teen Connection Project (TCP)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cognitive Therapy, Depression, Postpartum
RCT of Automated Conversational Agent vs. Treatment as Usual for the Management of Perinatal Mood
The purpose of this study is to investigate the efficacy of an evidence-based smartphone application (app) for the management of mood compared to treatment as usual alone among 135 women who have been discharged post-delivery…
- Conditions
- Cognitive Therapy, Depression, Postpartum, Mental Health, Depression
- Trial name
- NCT03646539
- Testing
- Use of smartphone application (app), Treatment as usual
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Stanford University
Depression
Working Memory Training for Dysphoric Students
Depression is associated with impairments in executive functions, including working memory (WM) which is needed to maintain and manipulate goal-relevant information.
- Trial name
- NCT02184481
- Testing
- Working memory training
- Where
- Netherlands
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Hyperlipidemias, Xerosis
Combined Effect of Acitretin and Narrow Band Ultraviolet B on Vitiligo Repigmentation
Since abnormal keratinocyte (KC) proliferation and differentiation as well as defective E cadherin expression were reported in vitiligo lesions, the investigators set to study the potential efficacy of combining Retinoids, which…
- Conditions
- Hyperlipidemias, Xerosis, Depression, Liver Diseases
- Trial name
- NCT04245319
- Testing
- Acitretin, Narrow band ultraviolet B
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Depression, Anxiety, Post-traumatic Stress Symptoms
Predictors and Process Moderators of EMDR Therapy for Depressive Symptoms
The goal of this clinical trial is to evaluate which factors influence the effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) therapy for depressive symptoms in real-world settings in Italy.
- Conditions
- Depression, Anxiety, Post-traumatic Stress Symptoms, Dissociation, Psychotherapy Research and Outcome Measures
- Trial name
- PROCESS-EMDR (NCT07033741)
- Testing
- EMDR
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Postpartum Depression
Peer Administered CBT for PPD
Postpartum depression (PPD) affects up to 20% of women and has profound effects on mothers and their infants. Unfortunately, fewer than 15% of women with PPD receive evidence-based care.
- Trial name
- PL-CBT (NCT03285139)
- Testing
- Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- McMaster University
Combat Disorders, Stress Disorders, Post-Traumatic
Motivational Interviewing to Engage Operations Enduring Freedom and Iraqi Freedom (OEF/OIF) Veterans in Mental Health Treatment
The goal of this randomized controlled trial is to evaluate the efficacy of telephone-administered motivational interviewing (TAMI) to enhance VA mental health treatment engagement among veterans of Operations Enduring Freedom…
- Conditions
- Combat Disorders, Stress Disorders, Post-Traumatic, Depression, Substance-Related Disorders
- Trial name
- NCT00419029
- Testing
- telephone-administered motivational interviewing, control
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- San Francisco Veterans Affairs Medical Center
Depression, Anxiety, PTSD
A Scalable Model for Promoting Functioning and Well-Being Among Veterans With a History of Mental Health Challenges Via Meaningful Social Interactions: Project V-SPEAK!
The goal of this study is to refine and test a strategy for engaging veterans with symptoms of depression and/or anxiety as volunteers to help English language learners (ELLs) improve their speaking skills via structured…
- Trial name
- V-SPEAK! (NCT05506839)
- Testing
- Intervention (videoconferencing)
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Postpartum Depression
Mobile Phone Based Peer Support to Prevent Postpartum Depression Among Adolescent Mothers
This pilot study will evaluate the feasibility and acceptability of a mobile phone based peer support intervention among adolescent mothers.
- Trial name
- NCT02818075
- Testing
- Mobile Phone Based Peer Support, Usual Care
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Stress Disorders, Post-Traumatic, Depression
Prospective Evaluation of Family Care Rituals in the ICU
This study will evaluate whether or not engaging family members of patients admitted to the ICU in "Family Care Rituals" will reduce stress related symptoms of PTSD, depression and anxiety 90 days after patient death or discharge…
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Anxiety
- Trial name
- FCR (NCT02875912)
- Testing
- Family Care Rituals
- Where
- 3 sites in United States, Italy
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Brown University
Major Depressive Disorder
Intradermal Acupuncture Based on Changes in Biological Specificity of Acupoints for Major Depressive Disorder
Acupoints are the stimulus points and reactive points for acupuncture to treat diseases. Therefore, this study is designed to detect the pain threshold and temperature of biological specificities of acupoints in healthy control…
- Trial name
- NCT05524519
- Testing
- Basic treatment, PSA, TSA
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
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