Clinical trials: Depressive Disorder NOS
Depression
Study Evaluating the Effects of DVS SR and Paroxetine on the Pharmacokinetics of Desipramine in Healthy Subjects
The purpose of this study is to evaluate the effects of multiple doses of DVS SR and paroxetine on the pharmacokinetics of a single dose of desipramine in healthy subjects.
- Trial name
- NCT00329147
- Testing
- desvenlafaxine SR, desipramine, paroxetine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Depression, Depressive Disorder, Major
The Feasibility, Usability and Satisfaction of an Online Tool for Perinatal Mental Health Problems
With this study the investigators aim to examine through a mixed method study the feasibility, usability and satisfaction with the developed online tool for perinatal mental health problems.
- Conditions
- Depression, Depressive Disorder, Major, Depression, Postpartum, Anxiety
- Trial name
- e-PMG (NCT06035159)
- Testing
- online psychotherapy
- Where
- Belgium
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Depression
Identification and Therapy of Postpartum Depression
This study will evaluate the effectiveness of a telephone-based depression screening and care management program in treating depression in postpartum women.
- Trial name
- NCT00282776
- Testing
- Care Management for Postpartum Depression, TAU
- Where
- United States
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Major Depression
Acupoint Thermal Radiation Characteristics in Adolescents with MDD
Modern studies have confirmed that skin temperature changes at acupoints when the body is under pathological conditions. This suggests that changes in the thermal radiation characteristics of acupoints can objectively respond to…
- Trial name
- NCT06750640
- Testing
- Infrared thermography
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xiaomei Shao
Major Depressive Disorder, Infrared Thermography
Assessing the Impact of Electroacupuncture on Facial Thermal Characteristics of Major Depressive Disorder Patients Based on Infrared Thermal Imaging Technology
Three groups of subjects will be included: 20 subjects in the healthy control group, 20 subjects in the MDD electroacupuncture (EA) intervention group, and 20 subjects in the MDD waiting-list group (participants will receive no…
- Trial name
- NCT05024149
- Testing
- infrared thermography (IRT)
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zhejiang Chinese Medical University
Major Depression
The Effect of Exercise on Depressive Symptoms in Unmedicated Patients
This trial investigates the biological effect of exercise training on depression. Participants will randomly be allocated to either a aerobic exercise group performing exercise on stationary bikes or a group performing low-impact…
- Trial name
- DEMOII (NCT00695552)
- Testing
- Aerobic exercise, Low impact exercise
- Where
- Denmark
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Major Depressive Disorder
Patient Stratification and Treatment Response Prediction in Neuropharmacotherapy Using Hybrid Positron Emmission Tomography/Magnetic Resconance Imaging (PET/MR)
Selective serotonin reuptake inhibitors (SSRIs) raise serotonin (5-HT) in the synaptic cleft and are the current first line of pharmacological antidepressive treatment.
- Trial name
- NCT02711215
- Testing
- PET/MR [11C]DASB, Citalopram, Escitalopram (Mirtazapine/Duloxetine/Venlafaxine)
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Major Depressive Disorder
Neural Components Underlying the Treatment of Adolescent Depression
The goal of the study is to examine how cognitive behavioral therapy (CBT), a common treatment for adolescent depression, affects brain functioning.
- Trial name
- NCT01717508
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Post-partum Depression
Virtual Patient Navigation During a Pandemic
The sub-study will involve a rigorous mixed-methods design. The qualitative phase of the sub-study will consist of semi-structured interviews.
- Trial name
- NCT06208852
- Testing
- Virtual Navigator Program
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Depression, Neurofeedback
Neurofeedback In Treatment Resistant Depression
The investigators evaluate the effects of neurofeedback as an augmentation treatment on depressive symptoms and functional recovery in patients with treatment-resistant depression (TRD).
- Trial name
- NCT04078438
- Testing
- neurofeedback augmentation, treatment as usual
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Yeungnam University Hospital
Postpartum Women
Breastfeeding, Maternal Functioning, and Resilience
This study aims to examine the effect of individualized home visits led by midwives on maternal functioning, breastfeeding attitudes, and depression levels.
- Trial name
- MLIHV (NCT07163871)
- Testing
- Postpartum hygiene, breast milk, and breastfeeding education have been provided for new mothers.
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Medine Yönder
Major Depressive Disorder
Model-based Defining of Subtypes of Depression and Optimal Treatment: an Integrated Techniques Module.
In this proposal, the investigators aim to explore the clinical subtypes and biological markers to personalize the use of antidepressants in MDD.
- Trial name
- NCT04518592
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Major Depressive Disorder
Treatment Response Biomarkers in MDD
This experiment intends to explore the differences among various types of depression, as well as the differences between healthy subjects and depressed patients, and find possible biological markers from the severity of symptoms…
- Trial name
- NCT05585047
- Where
- China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Zhang Yan
Major Depressive Disorder, Recurrent, Unspecified
Multiple Ascending Dose Study in Healthy Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY03005
Objectives To evaluate the safety and tolerability of escalating multiple oral doses of LY03005 in healthy subjects. To characterize the pharmacokinetics of escalating multiple oral doses of LY03005.
- Trial name
- NCT02271412
- Testing
- LY03005
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Luye Pharma Group Ltd.
Postpartum Depression, Postpartum Anxiety
The Maternal Well-Being Study
This project aims to understand the local feasibility and acceptability of MamaMeals (a home-delivered nutritious, postpartum meal delivery program) and MamaMatters (a moderated social media-based peer support group) among…
- Conditions
- Postpartum Depression, Postpartum Anxiety, Weight Retention, Postpartum, Nutritional and Metabolic Diseases
- Trial name
- MWB (NCT05484999)
- Testing
- Meals, Meals + Social Support, Control
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Healthy, Premenstrual Dysphoric Disorder
The Effects of Mixhers HERTIME Supplements on Menstrual Symptoms
The purpose of this study is to assess Mixhers HERTIME supplements efficacy in alleviating menstrual cycle symptoms.
- Conditions
- Healthy, Premenstrual Dysphoric Disorder, Premenstrual Syndrome
- Trial name
- NCT06136104
- Testing
- Mixhers HERTIME
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Healthy, Major Depression
Effects of Ghrelin on the Sleep-EEG and Nocturnal Secretion of Hormones
Ghrelin, an acylated peptide consisting of 28 amino acids, is the endogenous ligand of the growth hormone secretagogue receptor (GHS-R).
- Trial name
- NCT00447512
- Testing
- ghrelin
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Max-Planck-Institute of Psychiatry
Postpartum Depression, Quality of Life
Whether Probiotics Use in Neonate and Infant Improve Their Mother's Life Quality
Postpartum depression and poor quality of life during postpartum were an vital issue in recent years. Infant's health condition was thought to be a possible reasons related mother's postpartum quality of life, and functional…
- Conditions
- Postpartum Depression, Quality of Life, Functional Gastrointestinal Disorders, Probiotics
- Trial name
- NCT04741971
- Testing
- Probiotics group, Non-probiotics group
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Schizophrenia, Schizoaffective Disorder
Abilify Therapy for Reducing Comorbid Substance Abuse
It is hypothesized that the use of aripiprazole (Abilify) in patients with alcohol and/or drug dependence with comorbid psychiatric conditions will lead to: Reduction in the amount of alcohol and/or drugs used as measured by the…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depressive Disorder
- Trial name
- NCT00208169
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Creighton University
Psychosis
Immune Mechanisms of Antipsychotic Treatment Response
The aim of this study is to investigate the role of the immune system in psychotic symptoms and their response to treatment. The investigators will collect blood and cerebrospinal fluid samples from participants with psychosis…
- Trial name
- IMAT (NCT06687694)
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- King's College London
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