Clinical trials: Depressive Disorders
Psychological Distress
Lifestyle Hub Pilot Study
This study will examine the effects of a smartphone-based lifestyle medicine (LM) for improving psychological well-being in Chinese population.
- Trial name
- NCT04295369
- Testing
- Lifestyle Medicine
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Major Depressive Disorder
The Study of Serum Melatonin Rhythm Levels in Patients With Major Depressive Disorder
One of the main points in the biological trends is, the circadian rhythm and disturbance in this cycle, which cause mood disorders and irregularity in this bio clock, to get depression.
- Trial name
- NCT01357083
- Where
- Iran
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Science & Research Islamic Azad University Branch Khozestan
Depression, Anxiety, Trauma
Problem Management Plus Mindfulness-informed Legal Education for Addressing Gender-based Violence and Improving Parenting
Gender-based violence and, more specifically, domestic violence is a prevalent problem globally and in Nigeria. Its effect significantly impacts women and also the wellbeing of their families.
- Conditions
- Depression, Anxiety, Trauma, Anxiety, Parenting Intervention
- Trial name
- PM+MiLE (NCT06601023)
- Testing
- Psychosocial intervention
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Teesside University
Well-being, Psychological Capital
Problem Management Plus for Entrepreneurs
Conflict and unrest over three decades has resulted in significant economic decline in Khyber Pakhtunkhwa (KP) and Federally Administered Tribal Areas (FATA) of Pakistan and these now rank among the poorest regions in the…
- Conditions
- Well-being, Psychological Capital, Anxiety, Depression
- Trial name
- NCT03540927
- Testing
- PM+ for entrepreneurs, Cash transfer to the Entrepreneurs
- Where
- Pakistan
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Human Development Research Foundation, Pakistan
Depression, Anxiety
Black Youth M.A.T.T.E.R: Positive Youth Development Group Intervention
One in three Black boys born today in the United States will be incarcerated at some point in their lifetime, compared to one in 17 White boys. Black males are more likely to be arrested, convicted, and given unfair sentences.
- Trial name
- BYM (NCT03804242)
- Testing
- Black Youth M.A.T.T.E.R.: Molding Young Advocates While Transforming the School to Prison Pipeline Through Psychological Services Education and Resilience
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Depressive Symptoms, Anxiety
Probiotics, Brain Structure and Psychological Variables
Theory and research on the gut-brain-axis emphasize complex interactions between the gut microbiota, immunological and hormonal responses, brain function, brain structure, as well as resulting behavioral manifestations, such as…
- Conditions
- Depressive Symptoms, Anxiety, Stress
- Trial name
- ProBrain01 (NCT03478527)
- Testing
- Vivomixx® powder
- Where
- Germany
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Mental Health Disorder
Dissemination Strategies and Implementation Outcomes of Adolescent Character Strength Interventions.
The present research study will involve investigating the efficacy of large-scale dissemination models of evidence-based character strength interventions in secondary schools in Kenya.
- Trial name
- NCT05365503
- Where
- 3 sites in Kenya
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Shamiri Institute
Insomnia, Anxiety
Treating Comorbid Insomnia in Transdiagnostic Internet-Delivered Cognitive Behaviour Therapy
Transdiagnostic Internet-delivered Cognitive Behaviour Therapy (ICBT) is an efficacious treatment option for anxiety and depression; however, not all patients benefit equally and some leave treatment before program completion.
- Conditions
- Insomnia, Anxiety, Depression
- Trial name
- NCT04512768
- Testing
- Transdiagnostic Internet-delivered Cognitive Behaviour Therapy, Brief Internet-Delivered Cognitive Behaviour Therapy for Insomnia
- Where
- Canada
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- University of Regina
Late-Life Adults, Late-Life Prodromal Depression
Effects of Mindfulness or Brain Stimulation Intervention for Late-life Adults in Taiwan Urban and Rural Areas
This randomized controlled trial will examine the effects of mindfulness-based interventions and brain stimulation interventions on cognitive function and psychological well-being in older adults.
- Conditions
- Late-Life Adults, Late-Life Prodromal Depression, Late-Life Depression, Mindfulness
- Trial name
- PredictNPI (NCT07186023)
- Testing
- MBSR, MBWC, MBCI
- Where
- 2 sites in Taiwan
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Stress Disorders, Post-Traumatic, Depressive Disorder
Promoting Attachment Through Healing
Intimate partner violence (IPV) is a significant and pervasive public health challenge and is associated with mental illnesses such as depression, anxiety and posttraumatic stress disorder (PTSD).
- Conditions
- Stress Disorders, Post-Traumatic, Depressive Disorder, Anxiety Disorders
- Trial name
- PATH (NCT03536442)
- Where
- Canada
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Diabetes Mellitus, Type 2
Perceived Stress and Negative Thoughts With Biomarkers in People With Type 2 Diabetes Mellitus and Healthy Subjects
The purpose of this study is to determine the effect of measured and induced negative feelings on glucose, tumor necrosis factor alpha, and cortisol levels in healthy participants and participants with type 2 diabetes mellitus.
- Trial name
- NCT04387045
- Testing
- Guilty feelings
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Francisco Carlos López Marquez
Stress, Depressive Symptomatology
Emotional Experiences in Fathers of NICU Infants
This study is designed to evaluate the emotional experiences of fathers who have preterm infants who are hospitalized in a (neonatal intensive care unit)NICU setting.
- Trial name
- NCT00306605
- Testing
- Questionnaire
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Emotional Distress, Depression
The Dynamic Mechanism of Mindfulness Intervention for Emotional Distress (MIED) Based on Ecological Moment Measurement
The goal of this clinical trial is to examine how a mindfulness-based intervention (MIED) affects the moment-to-moment, lagged relationships between mechanism variables at the levels of feelings, thoughts, and behaviors and…
- Conditions
- Emotional Distress, Depression, Anxiety
- Trial name
- NCT07809737
- Testing
- Mindfulness Intervention for emotional distress(MIED）
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking University
Depression, Pregnancy Related
Treatment of Intrapartum Depression Using Non-invasive Photobiomodulation
Depression during pregnancy can cause fetal and maternal problems such as growth restriction, preterm labor, low birthweight, poor compliance and suicide.
- Conditions
- Depression, Pregnancy Related, Intrapartum Depression
- Trial name
- NCT04404231
- Testing
- Delivery of infrared light to the head, No Infrared treatment
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Dementia
Northern Manhattan Caregiver Intervention Project
Elderly Hispanics have a higher burden of dementia compared to Non-Hispanic Whites. Furthermore, Hispanic caregivers tend to have a higher burden of care for their relatives with dementia.
- Trial name
- NOCIP (NCT01306695)
- Testing
- New York University Caregiver Intervention (NYUCI), Community Health Worker (CHW) Case Management
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Columbia University
Depressive Symptoms, Anxiety
Asynchronous Techniques for the Delivery of Empirically Supported Psychotherapies
The aim of this study is to test the feasibility, acceptability and efficacy of methods for delivering mental health support when real-time communication is not possible (e.g.
- Conditions
- Depressive Symptoms, Anxiety, Stress, Impairment
- Trial name
- NCT05122429
- Testing
- e-Health Treatment
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Anxiety, Depression
Feasibility Testing a Meditation App for Professionals Working With Youth in the Legal System
This feasibility clinical trial aims to assess the feasibility of implementing a 1-month app-based meditation program with officers in the juvenile legal system and other professionals working directly with legal-involved youth.
- Conditions
- Anxiety, Depression, Burnout, Professional, Emotion Regulation
- Trial name
- NCT06555172
- Testing
- Action In Mindfulness (AIM)+, Resource+
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Depression - Major Depressive Disorder, Cognitive Flexibility
Cognitive Flexibility in Depression and TMS Response
The primary aim of this study is to determine the level of cognitive flexibility in patients with TRD before treatment and to explore whether there is a relationship with their response to TMS treatment.
- Conditions
- Depression - Major Depressive Disorder, Cognitive Flexibility, Treatment Response, Side Effects
- Trial name
- CogFelx_TMS (NCT06775054)
- Testing
- Transcranial Magnetic Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Bipolar Disorder, Depression
Brain Tissue Collection for Neuropathological Studies
The purpose of this study is to collect and study the brain tissue of deceased individuals to learn more about the nervous system and mental disorders.
- Conditions
- Bipolar Disorder, Depression, Anxiety Disorders, Schizophrenia
- Trial name
- NCT00001260
- Where
- 3 sites in United States
- Volunteers
- 2,161 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Alzheimer Disease, Dementia With Lewy Bodies (DLB)
Retrospective Observational Study of Blood-based Biomarkers in the Diagnosis and Monitoring of Patients With a Neurodegenerative Disease or Mental Disorder
This is a retrospective observational study to evaluate the clinical utility of blood-based biomarkers in the diagnosis and management of patients with a neurodegenerative disease (ND) or mental disorder (MD).
- Conditions
- Alzheimer Disease, Dementia With Lewy Bodies (DLB), Frontotemporal Dementia (FTD), Major Depressive Disorder (MDD)
- Trial name
- Synapsing-BK (NCT07314190)
- Where
- Spain
- Volunteers
- 1,799 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
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