Clinical trials: Depressive Disorders
Healthy Adults, Anxiety
Effect of Omega-3 Supplements on Stress, Anxiety, Depression, Memory and Sleep Quality Among Saudis
This study looked at whether taking omega-3 supplements can help reduce stress, anxiety, depression, and improve memory and sleep quality in Saudi adults who feel highly stressed or anxious.
- Conditions
- Healthy Adults, Anxiety, Depression, Sleep Quality
- Trial name
- OSADMS (NCT07157241)
- Testing
- Intervention
- Where
- Saudi Arabia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Prostate Cancer, Creative Arts Therapy
Creative Arts Therapy on Body Image, Self-esteem, Anxiety and Depression in Post-Treatment Prostate Cancer Patients
The goal of this clinical study is to assess the feasibility of implementing a creative arts therapy intervention of drawing and painting in Hong Kong prostate cancer patients and preliminarily examine the effects of this…
- Trial name
- NCT07015866
- Testing
- Guided therapy group, Creative arts therapy
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Depression
Interventions for Depressed Low Income Mothers and Their Infants
This study will compare three interventions for depressed, low income mothers and determine which is most effective in treating maternal depression and in fostering development in infants.
- Trial name
- NCT00105573
- Testing
- Maternal interpersonal psychotherapy (IP), Infant-parent psychotherapy, Informational meetings plus treatment as usual
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Depression
Preventing Postpartum Depression in African American Home Visiting Clients
The goal of this study is to determine whether a 6 week intervention is effective in preventing the worsening of depressive symptoms and development of clinical depression in low-income African American pregnant and recently…
- Trial name
- NCT01175603
- Testing
- Mothers and Babies Course (Adapted for Baltimore Home Visiting Programs)
- Where
- 4 sites in United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Depression / Major Depressive Disorder
Biomarkers and Pharmacogenomics for Precision Depression Therapy
Background: The clinical management of major depressive disorder (MDD) is hampered by the lack of objective biomarkers and high inter-individual variability in drug response, with conventional antidepressants achieving only a 50%…
- Trial name
- NCT07738497
- Testing
- Pharmacogenomic Testing, Antidepressant Agents
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Perfectionism, Anxiety
Treating Perfectionism Using Internet-Based Cognitive Behavior Therapy
Perfectionism is characterized by setting high standards and striving for achievement, sometimes at the expense of social relationships and wellbeing.
- Conditions
- Perfectionism, Anxiety, Depression, Stress
- Trial name
- NCT04459260
- Testing
- Cognitive Behavior Therapy, Unified Protocol
- Where
- Sweden
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Major Depressive Disorder
Evaluation of the Effects of Duloxetine on Norepinephrine
The purpose of this study is to evaluate how taking duloxetine 60mg every day affects the transfer of two normal body chemicals, 3,4-dihydroxyphenylglycol (DHPG) and norepinephrine (NE), across cells in blood and cerebrospinal…
- Trial name
- NCT00414323
- Testing
- Duloxetine, Escitalopram
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Depression
Effects of Light Treatment During Sleep on Young Men
This study will determine if green light exposure during sleep is effective in reducing mild depression symptoms in young men.
- Trial name
- NCT00796939
- Testing
- Green light mask, Red Light Mask
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Cognitive Dysfunction, Stroke
Vascular mEchanisms in, Stroke, dePression, dementiA, and deliRum: The VESPAR Project
The goal of this observational study is to determine the feasibility of using integrated Transcranial Doppler Ultrasonography or Near Infrared Spectroscopy to detect changes in cerebral autoregulation and neurovascular coupling…
- Conditions
- Cognitive Dysfunction, Stroke, Dementia, Depression
- Trial name
- VESPAR (NCT05649800)
- Where
- 2 sites in United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Breast Neoplasm Female, Symptom Cluster
Somatic Acupressure for Symptom Cluster Management in Breast Cancer Survivors
This study is designed following the updated Medical Research Council (MRC) Framework for Developing and Evaluating Complex Interventions.
- Trial name
- NCT06412107
- Testing
- True acupressure, Usual care
- Where
- 2 sites in China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Charles Darwin University
Healthy Subjects, Depressive Disorder and Anxiety Disorders
Study Of Safety, Blood Levels, And Brain Receptor Occupancy Of GSK163090 Using PET Imaging In Healthy Males
The purpose of this study is to look at how much of a new drug, GSK163090, binds to proteins in the brain and how much stays in the blood over a range of different doses.
- Trial name
- NCT00435695
- Testing
- GSK163090
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Major Depressive Disorder
Effect of Systemic Inflammation on Emotion and Cognition in Patients With Mood Disorder - A Vaccine Study
The purpose of this pilot study is to investigate and compare the effect of a mild inflammatory stimulus (typhoid vaccine) on immune response, mood and cognition in healthy volunteers compared to patients with history Major…
- Trial name
- NCT03523767
- Testing
- S.typhi Injection, Normal Saline Injection
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Depression in Old Age
Improving Adult Protective Services Client Outcomes: A Stepped-Care Social and Mental Health Engagement Program
The purpose of this study is to ascertain the feasibility and effectiveness of an 8-week social engagement program aimed at reducing depression and increasing social engagement among seniors who are transitioning out of Adult…
- Trial name
- NCT06257095
- Testing
- Stepped-care social and mental health engagement, APS Usual care
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Depression, Inflammation
Precision Psychiatry for Depression: Immune Response and Affective Symptoms as Predictors of Response to Antidepressants
Objectives: To identify in patients with major depression different peripheral markers of neuroinflammation in relation to affective symptoms (anxiety, depression, irritability), fatigue and cognitive symptoms; and its…
- Conditions
- Depression, Inflammation, Antidepressants, Immunity
- Trial name
- LYMPHODEP (NCT06337539)
- Testing
- SSRI
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Germans Trias i Pujol Hospital
Major Depressive Disorder
Tai Chi Training for Treating Depressed Chinese Americans
The goal of this research is to evaluate whether Tai Chi merits further investigation as a non-pharmacological therapy in the treatment of Major Depressive Disorder (MDD).
- Trial name
- NCT01263730
- Testing
- Tai Chi
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Depression
The Effects of Exercise on Depression Symptoms Using Levels of Neurotransmitters and EEG as Markers
The purpose of this study is to examine the effects of exercise on the symptoms of depression using serum levels of serotonin, catecholamine's, Alpha EEG asymmetry, and self-report of symptoms as markers.
- Trial name
- NCT02023281
- Testing
- Exercise
- Where
- 2 sites in United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Liberty University
Depressive Disorder, Major
A Study to Evaluate the Effect of Food on LY2216684
This study will evaluate the effect of food on LY2216684. There will be 2 study periods each lasting up to 5 days. There will be at least 7 days between the two doses and a follow up will occur at least 7 days after the last…
- Trial name
- NCT01389765
- Testing
- LY2216684
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Low Back Pain
Mindfulness Intervention to Reduce Low Back Pain Among Academicians
Mindfulness interventions are a well-known approach for improving mental health. Nevertheless, the available evidence regarding their efficacy in addressing musculoskeletal pain (MSP) is limited, despite numerous studies…
- Trial name
- NCT06214884
- Testing
- Mindfulness for All
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Obesity, Sleep
The Impact of Phone Use on Everyday Outcomes
Participants will download a phone-tracking app for a week to track phone usage, providing objective data on usage patterns. Quantitative tasks and questionnaires will also be carried out before and after the tracking period.
- Conditions
- Obesity, Sleep, Depression, Anxiety
- Trial name
- NCT04303637
- Testing
- Phone use
- Where
- Singapore
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Yale-NUS College
Depressive Symptoms, Anxiety
Evaluating an Online Wellness Intervention for Indian College Students
We are evaluating the effects of an online single-session mental health intervention (the Common Elements Toolbox; COMET). To evaluate COMET, we are conducting a randomized controlled trial with Indian college students.
- Conditions
- Depressive Symptoms, Anxiety, Happiness
- Trial name
- NCT04592588
- Testing
- Common Elements Toolbox, Wait-list control
- Where
- 2 sites in India
- Volunteers
- 513 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
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