Clinical trials: Depressive Disorders
Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Expanded Game Squad for Neurodiverse Youth
The proposed study will pilot the use of an adapted Game Squad intervention aimed at improving physical activity and other important health behaviors (nutrition, sleep hygiene, screen time habits) for children and adolescents…
- Conditions
- Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Health Behavior, Developmental Disorder
- Trial name
- NDGameSquad (NCT03665415)
- Testing
- NDGameSquad
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Merrimack College
Alcohol Use Disorder (AUD)
Process-Based Psychological Processes in Alcohol Use Disorder: A Case-Control Study Using PBAT, PHQ-9, and GAD-7
This observational study investigates differences in psychological processes and emotional symptoms between individuals with Alcohol Use Disorder (AUD) and a non-clinical control group. PBAT, PHQ-9, and GAD-7 will be used.
- Trial name
- PBAT Addiction (NCT07551830)
- Where
- Romania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Postpartum Women
Breastfeeding, Maternal Functioning, and Resilience
This study aims to examine the effect of individualized home visits led by midwives on maternal functioning, breastfeeding attitudes, and depression levels.
- Trial name
- MLIHV (NCT07163871)
- Testing
- Postpartum hygiene, breast milk, and breastfeeding education have been provided for new mothers.
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Medine Yönder
HIV Infections, Depression
The Influence of GINkGo Biloba on the Pharmacokinetics of the UGT Substrate raltEgraviR (GINGER)
The objective of this study is to evaluate the effect of ginkgo biloba (steady state) on the pharmacokinetics of a single dose of the UGT-substrate raltegravir. Furthermore the safety profile of the combination is studied.
- Conditions
- HIV Infections, Depression, Mild Cognitive Impairment
- Trial name
- GINGER (NCT01246804)
- Testing
- raltegravir single dose, ginkgo biloba multiple dose
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Depressive Symptoms, Anxiety
Evaluating an Online Wellness Intervention for Greek Adolescents
The investigators are evaluating the effects of an online single-session mental health intervention (the Common Elements Toolbox; COMET).
- Conditions
- Depressive Symptoms, Anxiety, Happiness
- Trial name
- NCT04815681
- Testing
- Common Elements Toolbox, Active Control
- Where
- 2 sites in United States, Greece
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Major Depressive Disorder
Model-based Defining of Subtypes of Depression and Optimal Treatment: an Integrated Techniques Module.
In this proposal, the investigators aim to explore the clinical subtypes and biological markers to personalize the use of antidepressants in MDD.
- Trial name
- NCT04518592
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Anxiety, Depression
Exploring Use of Internet-Delivered Cognitive Behaviour Therapy (ICBT) by Diverse Ethnocultural People of Saskatchewan
In an attempt to increase timely and accessible psychological treatment for depression and anxiety, Internet-delivered Cognitive Behaviour Therapy (ICBT) has emerged.
- Trial name
- NCT05523492
- Testing
- Internet-delivered Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Regina
Depression
Mechanisms of Behavioral Activation (BA)
The investigators will be comparing brain (neural) activation of depressed adolescent patients before, during and after a course of Behavioral Activation (BA) therapy using functional magnetic resonance imaging (fMRI).
- Trial name
- NCT05548244
- Testing
- Behavioral Activation Therapy, Baseline assessment procedures
- Where
- 3 sites in United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Emory University
Major Depressive Disorder
Treatment Response Biomarkers in MDD
This experiment intends to explore the differences among various types of depression, as well as the differences between healthy subjects and depressed patients, and find possible biological markers from the severity of symptoms…
- Trial name
- NCT05585047
- Where
- China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Zhang Yan
Major Depressive Disorder, Recurrent, Unspecified
Multiple Ascending Dose Study in Healthy Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY03005
Objectives To evaluate the safety and tolerability of escalating multiple oral doses of LY03005 in healthy subjects. To characterize the pharmacokinetics of escalating multiple oral doses of LY03005.
- Trial name
- NCT02271412
- Testing
- LY03005
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Luye Pharma Group Ltd.
Postpartum Depression, Postpartum Anxiety
The Maternal Well-Being Study
This project aims to understand the local feasibility and acceptability of MamaMeals (a home-delivered nutritious, postpartum meal delivery program) and MamaMatters (a moderated social media-based peer support group) among…
- Conditions
- Postpartum Depression, Postpartum Anxiety, Weight Retention, Postpartum, Nutritional and Metabolic Diseases
- Trial name
- MWB (NCT05484999)
- Testing
- Meals, Meals + Social Support, Control
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Healthy, Premenstrual Dysphoric Disorder
The Effects of Mixhers HERTIME Supplements on Menstrual Symptoms
The purpose of this study is to assess Mixhers HERTIME supplements efficacy in alleviating menstrual cycle symptoms.
- Conditions
- Healthy, Premenstrual Dysphoric Disorder, Premenstrual Syndrome
- Trial name
- NCT06136104
- Testing
- Mixhers HERTIME
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Healthy, Major Depression
Effects of Ghrelin on the Sleep-EEG and Nocturnal Secretion of Hormones
Ghrelin, an acylated peptide consisting of 28 amino acids, is the endogenous ligand of the growth hormone secretagogue receptor (GHS-R).
- Trial name
- NCT00447512
- Testing
- ghrelin
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Max-Planck-Institute of Psychiatry
Liver Cancer, Anxiety Disorder
Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family Caregivers
The study intervention consists of the early integration of palliative care services into standard oncology care in an outpatient setting for patients with advanced lung and non-colorectal gastrointestinal malignancies who are…
- Conditions
- Liver Cancer, Anxiety Disorder, Depression, Small Cell Lung Cancer
- Trial name
- NCT02349412
- Testing
- Early palliative care
- Where
- 23 sites in United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Postpartum Depression, Quality of Life
Whether Probiotics Use in Neonate and Infant Improve Their Mother's Life Quality
Postpartum depression and poor quality of life during postpartum were an vital issue in recent years. Infant's health condition was thought to be a possible reasons related mother's postpartum quality of life, and functional…
- Conditions
- Postpartum Depression, Quality of Life, Functional Gastrointestinal Disorders, Probiotics
- Trial name
- NCT04741971
- Testing
- Probiotics group, Non-probiotics group
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Depression, Loneliness
VOICES Socials for Older Veterans With Depression
VOICES Veterans Socials (VS) support Veterans in the community through weekly social groups. Veterans socials have the potential to improve social functioning, mental health symptoms, and create lasting social support.
- Conditions
- Depression, Loneliness, Isolation
- Trial name
- NCT06145334
- Testing
- Veterans Social
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Anxiety, Depression
A Randomized-Controlled Trial to Investigate the Effect of a Novel Music Therapy Application to Reduce Anxiety and Stress
This virtual, open-label, three-group, randomized-controlled trial will last six weeks. Participants will be allocated into three groups; the Intervention Group, Spotify Group, and Control Group.
- Conditions
- Anxiety, Depression, Stress
- Trial name
- NCT06021821
- Testing
- SoundMind App, Spotify Playlist
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- SoundMind
Depression, Anxiety
Description of the Lived Experiences of Family Caregivers for People With Mental Health Comorbidities
Mental health problems such as depression, trauma and anxiety are common in low-resource contexts, such as Zambia. Comorbidity, or having multiple mental health problems, is the norm.
- Conditions
- Depression, Anxiety, Trauma
- Trial name
- MCE (NCT07760701)
- Where
- Zambia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
Bipolar Disorder, Depression, Bipolar
Study of a Vestibular Biomarker of Phase in Bipolar Disorder
Bipolar Disorder show cyclic changes of mood between depression (depressive phase) and mania (maniac phase). Vestibular tests have been shown high sensibility and specificity as a biological marker for major depression.
- Trial name
- BDmarker (NCT02827045)
- Testing
- Vestibular test
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vest Brain,Centro de Estudios Neurovestibulares
Rotator Cuff Tears
Central Neuromuscular Dysfunction, Functionality, Psychological Status and Rotator Cuff Surgery
Considering the fact that The problems experienced by the patients are not only physiological but also psychological and social. Unfortunately, there is no sufficient study focus on all these concepts.
- Trial name
- NCT05566470
- Testing
- Assessment of Central Neuromuscular Dysfunction, Shoulder Physical Functionality and Psychological Factors
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
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