Clinical trials: Depressive Disorders
Depression, Anxiety
Transparent Communication to Improve Mental Wellbeing and Attitude Towards Reintegration
Reintegrating those once affiliated with proscribed terrorist groups constitutes significant global challenges due to public stigma, poor awareness of reintegration programmes and resentment towards incentives provided to…
- Conditions
- Depression, Anxiety, Trauma, Stress
- Trial name
- NCT07251478
- Testing
- Prosociality, Empathy and Awareness Communication to aid rEintegration (PEACE)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Teesside University
Antenatal Depression, Antenatal Anxiety
Effectiveness and Cost-effectiveness of Simultaneous Screening and Intervention for Antenatal Depression and Anxiety Symptoms From a Transdiagnostic Perspective: A Scale-up Feasibility Study
This scale-up study aimed to explore the effectiveness of simultaneous screening and intervention of antenatal depression and anxiety in preventing postpartum depression and anxiety and how scale-up might be successfully…
- Trial name
- NCT07349368
- Testing
- implementation group
- Where
- China
- Volunteers
- 3,314 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
Depressive Symptoms, Stress
Investigating Differential Effects of Online Mental Training Interventions on Mental Well-being and Social Cohesion
The SARS-CoV-2 pandemic, and the associated government-imposed isolationary lockdowns, has led to a mental health crisis on a global scale.
- Conditions
- Depressive Symptoms, Stress, Empathy, Compassion
- Trial name
- NCT04889508
- Testing
- Socio-emotional mental training, Mindfulness-based mental training
- Where
- Germany
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Max Planck Social Neuroscience Lab
Motivation, Hope
The Effect of Hope-focused Motivational Interview on Individuals Receiving Hemodialysis Treatment
Chronic kidney failure (CRF) is an important health problem in the world and in our country. The use of hemodialysis as a treatment method has prolonged the life span of individuals with CRF; challenging and long treatment…
- Conditions
- Motivation, Hope, Stress, Anxiety
- Trial name
- NCT04927923
- Testing
- hope-focused motivational interview
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Serife Bilge Duran
Current Major Depressive Disorder, Healthy
Evaluating Brain Responses to Facial Expressions in Major Depressive Disorder
This study will evaluate emotional processing biases in the brain while viewing facial expressions in adults with current or remitted major depressive disorder and healthy volunteers.
- Conditions
- Current Major Depressive Disorder, Healthy, Remitted Major Depressive Disorder
- Trial name
- NCT00071123
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Breastfeeding Self-efficacy, Maternal Attachment
The Effect Of Postpartum Therapeutıc Touch On Breastfeedıng Self-Effıcacy, Maternal Attachment, And Postpartum Depressıon In Prımıparous Women: A Randomızed Controlled Study
The postpartum period, also known as the fourth trimester, begins with the birth of the baby and lasts approximately 6-8 weeks, varying from person to person.
- Trial name
- NCT07693010
- Testing
- therapeutic touch, terapötik dokunma
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Major Depressive Disorder
Stress and the Sympathetic Nervous System in Adults With Depression
To test our hypotheses, we will enroll healthy adults having no history of mood disorders and adults with major depressive disorder (MDD) having a broad range of depressive symptom severity.
- Trial name
- NCT04838262
- Testing
- Acute Stressors
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Depression and Anxiety Symptom, Anger
Implementing BEAM: A Scalable Digital Mental Health Program, for Families of Children Referred to Neurodevelopmental Services
Families of children with neurodevelopmental differences (NDDs) experience disproportionately high levels of parenting stress and mental health difficulties, including elevated depression, anxiety, and caregiver burden.
- Conditions
- Depression and Anxiety Symptom, Anger, Parenting, Stress (Psychology)
- Trial name
- NCT07837791
- Testing
- The Building Emotional Awareness and Mental Health (BEAM) Program
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Emotional Disturbances, Depression
Healthy Lifestyle Intervention for High-Risk Minority Pregnant Women
The overall purpose of this application is to evaluate the efficacy of an intervention designed to decrease health disparities in pregnant, emotionally distressed, minority women.
- Conditions
- Emotional Disturbances, Depression, Pregnancy Late, Post-Partum Depression
- Trial name
- A-RCT (NCT03416010)
- Testing
- COPE-P
- Where
- 3 sites in United States
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Therapeutic Touch, Menopausal Symptoms
The Effects of Reiki on Menopausal Symptoms and Depression Levels
Objective: This study was conducted to determine the effects of Reiki applied to women in the postmenopausal period on menopausal symptoms and depression levels.
- Trial name
- NCT05977426
- Testing
- Reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Inonu University
Mental Disorders, Mood Disorders
PET Neuroimaging of [11C]Mirtazapine
Recent studies show that 25 - 30% of depressed patients never fully recover, resulting in a treatment-resistant condition. Thus, depression is a major cause of human suffering.
- Conditions
- Mental Disorders, Mood Disorders, Affective Disorders, Depressive Disorders
- Trial name
- NCT00288782
- Testing
- Mirtazapine
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Systemic Lupus Erythematosus
Fatigue, Depression, and Cortical Excitability in Systemic Lupus
Systemic lupus erythematosus is a chronic inflammatory autoimmune disease with an unknown cause and many challenges. Whilst corticosteroids and effective immunosuppressive therapy have transformed the management of patients with…
- Trial name
- NCT03165682
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Assiut University
Violence, Domestic, Stress Related Disorder
Applied Social Neuroscience: the Building Resilience Among Women Project
Intimate partner violence (IPV) is the most common and alarming form of violence against women, affecting up to 25% of all women in Catalonia.
- Conditions
- Violence, Domestic, Stress Related Disorder, Depressive Disorder
- Trial name
- BRAW (NCT03623555)
- Testing
- Trier Social Stress Test, Salivary cortisol
- Where
- Spain
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Ximena Goldberg
Alzheimer Disease, Depression
Eye Movement Recording as an Early Differential Diagnostic Tool for Alzheimer/Depression
The global aim of our study is to validate eye movement recording as an early differential diagnostic tool, in order to discriminate as early as possible between neurodegenerative dementias of Alzheimer type and depressive…
- Trial name
- MOMAD (NCT01434940)
- Testing
- Eye movements will be recorded using video-oculography techniques based on both the corneal reflection principle and an infra-red light beam
- Where
- France
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Major Depressive Disorder
Acupuncture for Patients With Major Depressive Disorder
Several studies investigating acupuncture for major depressive disorder (MDD) have been carried out. However, investigators found the results were in high heterogeneity and poor methodological quality.
- Trial name
- NCT05106868
- Testing
- acupuncture
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Bipolar Disorder, Bipolar I Depression
Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder
Lithium is highly effective in the treatment of bipolar disorder. This study aims to investigate, for the first time, the impact of lithium monotherapy on the structural and functional connectivity of the brain using MRI imaging.
- Conditions
- Bipolar Disorder, Bipolar I Depression, Bipolar II Depression, Bipolar Depression
- Trial name
- NCT03336918
- Testing
- Lithium
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pregnancy, Postpartum
HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children
Regular exercise during pregnancy and postpartum leads to health benefits for mother and child. Inactivity during pregnancy and after delivery is now treated as risky behavior.
- Conditions
- Pregnancy, Postpartum, Childbirth, Health Status
- Trial name
- HIIT MAMA (NCT05009433)
- Testing
- High intensity interval training program for pregnant women, Moderate intensity continuous training program for pregnant women, Standard obstetric care with extended education on healthy lifestyle
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Fibromyalgia, Anxiety
The Relationship Between Diaphragm Muscle Thickness and Fibromyalgia
Fibromyalgia syndrome is characterized by chronic pain, fatigue, sleep problems and functional symptoms. Fatigue, anxiety and depression disorders, poor quality of life, sleep disorders, decreased concentration, and impaired…
- Conditions
- Fibromyalgia, Anxiety, Depression, Diaphragm Issues
- Trial name
- NCT06396949
- Testing
- Fibromyalgia study form, Pulmonary function test, Ultrasonographic Diaphragm Thickness Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Bipolar Depression
Proof Of Mechanism Study To Determine Efficacy Of PF-04455242 In Blocking Spiradoline (PF-00345768) Stimulated Prolactin Release
This study will be a Proof of Mechanism (POM) study to establish evidence of central pharmacodynamic activity for PF 04455242, and will be a parallel group, randomized, double blind, sponsor open study conducted in healthy male…
- Trial name
- NCT00988949
- Testing
- PF-04455242, spiradoline
- Where
- Singapore
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
Depressive Disorder, Treatment-Resistant
In Vitro Modeling of Drug-resistant Psychiatric Disorders Using Induced Pluripotent Cells
Major depressive disorder (MDD), is a major medical and economic burden for today's society. About 30% of MDD patients develop treatment-resistant depression - TRD with the related sequelae in terms of worse prognosis.
- Trial name
- NCT05887310
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.