Clinical trials: Depressive Disorders
Depression
Study to Evaluate the Effectiveness of Certain Selective Serotonin Reuptake Inhibitor (SSRI) Antidepressants During Pregnancy and Evaluate Newborn Outcomes
The purpose of this study is to evaluate if during pregnancy, a common group of antidepressant medications (SSRI's) adequately treats the symptoms of depression and to evaluate if there are any effects of these medications on the…
- Trial name
- NCT00553917
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Indiana University
Stroke
Online Mindfulness for Stroke Sufferers
A feasibility study to investigate the effect of an online mindfulness programme (www.bemindfulonline.com) on stroke survivors' mental and physical wellbeing.
- Trial name
- NCT03368950
- Testing
- Online Mindfulness Course
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Anxiety, Depression
COVID-19 and the Healthy Minds Program for Educators
This study is a randomized controlled trial (RCT) of the four-week Healthy Minds Program (HMP) app Foundations training in employees of a mid-size urban school district in the United States during the summer of 2020, in the midst…
- Conditions
- Anxiety, Depression, Psychological Stress, Psychological Distress
- Trial name
- CAHMP-ED (NCT04426318)
- Testing
- Healthy Minds Program Foundations Training
- Where
- United States
- Volunteers
- 698 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Atopic Dermatitis, Psoriasis
Clinical, Psychological and Genetic Characteristics in Dermatological Patients
Atopic dermatitis (AD) and psoriasis (PS) are chronic, relapsing dermatological disorders with a high rate of psychiatric co-morbid pathology represented with depression.
- Trial name
- NCT03831646
- Where
- Kazakhstan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Astana Medical University
Depressive Symptoms, Anxiety
Promoting Maternal Mental Health and Wellbeing in Neonatal Intensive Care
This small randomized pilot study will evaluate feasibility and preliminary outcomes of an audio-delivered mindfulness program to reduce psychological distress for mothers with an infant in neonatal intensive care, as compared…
- Conditions
- Depressive Symptoms, Anxiety, Post-traumatic Stress Symptoms
- Trial name
- NCT03942627
- Testing
- Mindfulness Program, Infant Health Education Program
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Major Depression (in Remission)
Investigating the Mechanisms of Mindfulness-based Cognitive Therapy (MBCT)
This research will investigate the neuropsychological mechanisms underlying the eight-week Mindfulness-based Cognitive Therapy (MBCT) programme.
- Trial name
- NCT02226042
- Testing
- Mindfulness-based Cognitive Therapy
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Post-traumatic Stress Disorder, Traumatic Brain Injury
Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop
In this proposal, the investigators extend their previous SPiRE feasibility and preliminary effectiveness study to examine STEP-Home efficacy in a RCT design.
- Conditions
- Post-traumatic Stress Disorder, Traumatic Brain Injury, Substance Related Disorders, Depression
- Trial name
- STEP-Home (NCT03868930)
- Testing
- STEP-Home, PCGT
- Where
- 2 sites in United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cancer and Non-cancer Hospice Patients
Virtual Reality for Improving Symptoms in Palliative Care
The objective of this study is to determine whether VR can ameliorate symptoms for palliative care patients within a hospice setting.
- Trial name
- VRPC (NCT05197894)
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Sleep Disturbances, Depression
Neurobiological Investigations of Mindfulness, Depression and Sleep Disturbances in Medical Staffs and Community Elders
The research team proposes a multi-year study with the first year focusing on the developmental phase. In this initial phase, we aim to recruit 40 participants (including healthcare staff and older adults) from Shuang-Ho Hospital…
- Trial name
- NIMDS (NCT07179172)
- Testing
- Mindfulness-Based Stress Reduction (MBSR) 8-Week Program
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Depression, Anxiety
Online Wellness Intervention for College Students
We are evaluating the effects of an online single-session mental health intervention (the Common Elements Toolbox; COMET). To evaluate COMET, we are conducting a randomized controlled trial with college students attending…
- Conditions
- Depression, Anxiety, Well-being
- Trial name
- NCT04740411
- Testing
- The Common Elements Toolbox (COMET)
- Where
- United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Anxiety Depression Disorder
Hemispheric Asymmetries in Emotion-Cognition Interactions
In this research, the investigators will recruit 2 groups of individuals: older adults (aged over 65) with anxiety and/or depression and older adults without mental health issues.
- Trial name
- NCT06406595
- Testing
- Observation
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Ulcerative Colitis, Crohn Disease
Influence of Aerobic Exercise Training (AET) on Inflammatory Bowel Disease (IBD) in Children and Adolescents
The purpose of this study is to determine if aerobic exercise training can serve as comprehensive palliative care, whereby enhancing cardiovascular fitness, mitigating depressive symptoms and augmenting sleep while bolstering…
- Conditions
- Ulcerative Colitis, Crohn Disease, Depression, Sleep
- Trial name
- Ex-CED (NCT02264275)
- Testing
- Aerobic Exercise Training
- Where
- 3 sites in Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Basel
Depressive Disorder
The Effect of Duloxetine on Interoceptive Awareness
This study focuses on possible mechanism mediating duloxetine effects on painful physical symptoms in patients suffering from MDD.
- Trial name
- NCT00337012
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Social Anxiety, Major Depression Mild
Transdiagnostic REBT Prevention Program for Adolescents
Anxiety and depressive disorders are common in adolescents, however they are often unrecognized. Rational emotive behavioral therapy (REBT), a form of cognitive behavioral therapy (CBT) is efficient for children and adolescents.
- Conditions
- Social Anxiety, Major Depression Mild, Panic Disorder, Specific Phobia
- Trial name
- NCT02756507
- Testing
- video-based transdiagnostic REBT, Wait list
- Where
- Romania
- Volunteers
- 381 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Dementia, Malnutrition
Patient Participation in Prevention of Loss of Functions
Randomized Clinical Trial (RCT) To investigate and compare the effect of two preventive interventions on readmission rates, loss of functions, quality of life and cost-benefit.
- Conditions
- Dementia, Malnutrition, Depression, Pain
- Trial name
- NCT01843907
- Testing
- Empowerment, Conversation with nurse
- Where
- Denmark
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Covid-19, Mental Health Disorder
The Covid-19 HEalth caRe wOrkErS (HEROES) Study
Since December 2019 the world has been shaken with an enormous global threat: the Covid-19 pandemic. This new kind of coronavirus is generating an unprecedented impact both on the general population and on the healthcare systems…
- Conditions
- Covid-19, Mental Health Disorder, Stress Disorder, Anxiety
- Trial name
- HEROES (NCT04352634)
- Testing
- Exposure to the SARS-CoV-2 and its consequences
- Where
- 22 sites in United States, Argentina and 19 more
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Chile
Depression
A Study of HR071603(Ketamine Nasal Spray) in Healthy Subjects
The study is being conducted to evaluate the safety and pharmacokinetics of HR071603 in healthy subjects.
- Trial name
- NCT04108234
- Testing
- HR071603
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Pediatric Obesity, Mental Health Wellness 1
The Family Stress Study - Chronic Stress and Child Adiposity: Testing a Bio-behavioural Model
The Family Stress Study is following families with young children in Guelph, Hamilton and surrounding areas over 3 years to understand how chronic stress impacts children's weight gain over time and how this association is…
- Trial name
- NCT05534711
- Where
- 2 sites in Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Parkinson's Disease, Depression
Validation of the Hebrew Version of the Montreal Affective Voices.
Today, no non-verbal auditory stimuli that assess mental processing are available in Israel. The goal of this study is to make available a validated set of auditory stimuli in Israel.
- Trial name
- NCT01512732
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Major Depressive Disorder (MDD)
Single Dose Oral Bioequivalence Study of Vortioxetine Hemihydrobromide Orally Disintegrating Tablets
An open label, randomized, three-period, three-treatment [Treatment A (test product administered without water), Treatment B (test product administered with water) and Treatment C (Reference product administered with water)]…
- Trial name
- NCT05417087
- Testing
- Vortioxetine Hemihydrobromide Orally Disintegrating Tablets, Vortioxetine Hydrobromide Tablets
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Seasons Biotechnology (Taizhou) Co., Ltd.
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