Clinical trials: Depressive Disorders
Mental Health Wellness 1, Depression
Addressing Mental Health of Cancer Patients and Caregivers Using a Mobile App Suite
A cancer diagnosis affects not only patients but also their caregivers. The purpose of this study is to test the feasibility of using a mobile app suite, IntelliCare, to improve the mental health of cancer patients and caregivers.
- Conditions
- Mental Health Wellness 1, Depression, Anxiety
- Trial name
- NCT03488745
- Testing
- IntelliCare + Phone Coaching
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Depression, Anxiety
Effect of Music Therapy in Mental Subhealth (EMTMS)
Mental health is increasingly at the forefront of concerns, especially since the start of COVID-19 pandemic. However, not all individuals under mental subhealth need pharmaceutical treatment.
- Trial name
- NCT05648539
- Testing
- The mini apps named "SOUL GYM" on the Wechat
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Nanjing Brain Hospital
Major Depressive Disorder, Major Depressive Episode
MRS and Medication Response: A Pilot Study
We hope to demonstrate that magnetic resonance spectroscopy can detect brain concentration levels of paroxetine (Paxil) or citalopram (Celexa) or escitalopram (Lexapro) in depressed patients.
- Conditions
- Major Depressive Disorder, Major Depressive Episode, Major Depressive Disorder, Recurrent, Major Depression Mild
- Trial name
- NCT03254342
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Stanford University
Healthy Participants, Anxiety Disorders (With High Anxiety Symptoms)
tVNS and Approach-Avoidance Behavior in Anhedonia and Anxiety
This study investigates if anhedonia and anxiety symptoms are associated with alterations in reinforcement learning, effort trade-offs for wins vs. punishments, and foraging behavior under threat.
- Conditions
- Healthy Participants, Anxiety Disorders (With High Anxiety Symptoms), Depressive Disorders (With High Anhedonia Symptoms), Comorbid Depression and Anxiety Disorder (With High Anhedonia and High Anxiety Symptoms)
- Trial name
- NCT07476469
- Testing
- tVNS
- Where
- Germany
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Dr. Nils B. Kroemer
Tracheotomised Children, Anxiety of Parents
Parental Mental Health After Tracheostomy in Early Childhood
To assess the prevalence of anxiety / depression in post- hospital for parents (mothers and fathers) of children with tracheotomy before the age of 1 year between 2000 and 2012.
- Conditions
- Tracheotomised Children, Anxiety of Parents, Depression of Parents
- Trial name
- TRACH (NCT02884570)
- Testing
- Auto-Questionnaires
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Major Depressive Disorder, Mood Disorders
Psychobiological Markers to Improve Diagnosis and to Predict Affective Episodes in Bipolar Disorder
This trial has two studies. In study 1, the investigators will explore the relationships between three psychobiological factors (sleep patterns, motor activity, and decision-making ability).
- Conditions
- Major Depressive Disorder, Mood Disorders, Bipolar Disorder (BD)
- Trial name
- MoodCatcher (NCT07427966)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Anxiety, Panic Disorder
Investigation of Pathogenic Gut Microbiota Patterns in Anxiety, Depression and Panic Disorders
This study aims to investigate the etiology of anxiety, depression, and panic disorders, providing new evidence and insights into the root causes and effective treatments, potentially offering a novel approach to achieving…
- Conditions
- Anxiety, Panic Disorder, Mood Disorders, Depression
- Trial name
- NCT07268729
- Testing
- H pylori stool test, Bacterial stool analysis
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Toronto
PostPartum Depression
The Effect of Exercise on Preventing PostPartum Depression
The purpose of this study is to examine the feasibility and efficacy of an exercise intervention for the prevention of postpartum depression.
- Trial name
- NCT00961402
- Testing
- Wellness Control, Exercise Intervention
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Postpartum Depressive Mood, Postpartum Sexual Function
Oral Contraceptive Ethinyl Estradiol Dose Effect on Postpartum Depression and Sexual Functioning Scales
This is a prospective, randomized, controlled cohort study. This study will look at the effect of Ethinyl Estradiol 35mcg/Norethindrone 1mg and Ethinyl Estradiol 20 mcg/Norethindrone 1mg on postpartum depressive symptoms and…
- Trial name
- NCT02210702
- Testing
- Ethinyl Estradiol 35mcg/Norethindrone 1mg, Ethinyl Estradiol 20mcg/Norethindrone 1mg
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- The Jones Institute
Depression
Study of the Effect of a Cognitive Task on Static Balance in Depressive Elderly Subjects According to the Double Task Principle
This study could contribute to understanding the aggravation of balance disorders and the increased risk of falling in depressive people.
- Trial name
- DOUBLE TACHE (NCT01950754)
- Testing
- standing with both feet, descent of the platform, standing on the platform, feet together and always with simultaneous performance of a task of mental count
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Treatment Adherence and Compliance, Anxiety
Global Controlled Trial on Effects of an Online Self-Help Program for of Ambitious Altruists on Their Mental Health, Wellbeing, and Productivity: Comparing Versions With IFS vs. CBT, Buddy- vs. Group-, Standard- vs. Minimum-Guidance Intensity.
This study aims to compare different versions of a 16-week online self-help program in terms of their effect on self-assessed mental health, well-being, and productivity.
- Conditions
- Treatment Adherence and Compliance, Anxiety, Depression, Mental Health Issue
- Trial name
- CT_DoBetter (NCT06442072)
- Testing
- guided online self-help program
- Where
- Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rethink Wellbeing
Health Care Utilization
The Effect of Video-based Testimonials About Psychotherapy on Treatment Expectations and a Short Online Intervention
Research has shown that treatment expectations play a major role in the course of mental disorders and that positive expectations have a beneficial impact on treatment outcomes.
- Trial name
- NCT05826886
- Testing
- Emotional Writing
- Where
- Germany
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Prostate Cancer, Creative Arts Therapy
Creative Arts Therapy on Body Image, Self-esteem, Anxiety and Depression in Post-Treatment Prostate Cancer Patients
The goal of this clinical study is to assess the feasibility of implementing a creative arts therapy intervention of drawing and painting in Hong Kong prostate cancer patients and preliminarily examine the effects of this…
- Trial name
- NCT07015866
- Testing
- Guided therapy group, Creative arts therapy
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Dyspepsia
Heterogeneous Distribution of Health Literacy and Emotional State on Patients With Functional Dyspepsia.
Patients with indigestion were often found in gastroenterology clinic, those who about 20 % was caused by organic, while the rest of patients are showed abnormal inspection, and these are so called functional dyspepsia.
- Trial name
- NCT02737683
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Expectant Couples
"Becoming Parents": A Hospital-community Partnership
The proposed of this study is to determine if an intervention, known as the "Becoming Parents" programme, is more effective in improving the mental health, marital relationship and parental competence of expectant couples in a…
- Trial name
- NCT01383551
- Testing
- "Becoming Parents" intervention
- Where
- Hong Kong
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Postnatal Depression
Postnatal Depression, Attachment and Self-defining Memories
The specificity of postnatal depression (PND) was acted as full entity within the depressions, by B. Pitt in 1968, through the description of a specific nosography which describes "an atypical depression of the post-partum ".
- Trial name
- PNDattachMEMO (NCT03346551)
- Testing
- Evaluation of the quality attachment : "Adult Attachment Narratives" and "CaMir scale", Evaluation of the self-defining memories : "Specific Questionnaire during an interview"
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Major Depressive Disorder, Anhedonia
Kappa Opioid Receptor Imaging in Depression (KOR Depression)
The purpose of this study is to use positron emission tomography (PET) imaging to measure the activity of the kappa opioid receptor (KOR) in the brains of depressed and non-depressed individuals.
- Trial name
- NCT02236702
- Testing
- Positron Emission Tomography (PET) imaging
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Major Depressive Disorder, Bipolar Disorder
An Eye Tracking Study of Affective Disorder Patients With Suicide Risk
This research tries to investigate the validity and reliability of eye-tracking technologies by using different paradigms (eg. free-view, pro-saccade and anti-saccade) which served as a novel way of evaluating suicide risk among…
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Suicide
- Trial name
- NCT03711045
- Testing
- eye-tracking
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central South University
Depressive Disorder
Effect of Nicotine on Brain Reward Pathways
The investigators will determine whether an acute dose of nicotine, in the form of the nicotine lozenge, impacts brain and behavioral measures of mood and reward responsiveness in individuals with major depressive disorder.
- Trial name
- NCT02346539
- Testing
- Nicotine polacrilex
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Depression, Loneliness
Nature-Oriented Chatbots on Older Adults' Mental Health
This study aims to explore the influence of nature-oriented chatbots on the mental health of older adults residing alone. Leveraging the therapeutic potential of nature exposure and the interactive capabilities of chatbot…
- Conditions
- Depression, Loneliness, Happiness, Connection With Nature
- Trial name
- NCT06423027
- Testing
- Nature-Oriented Chatbots
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
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