Clinical trials: Depressive Illness
Bariatric Surgery, Depression
Laughter Yoga Effect Depression, Serotonin Levels With Bariatric Surgery Patient
The goal of this a quasi-trial model with pre and post-test control group is to determine the effect of laughter yoga on depression and serotonin levels in patients undergoing bariatric surgery.
- Trial name
- NCT06020079
- Testing
- laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Major Depressive Disorder
Efficacy and Safety Study of SPD489 in Combination With an Antidepressant in the Treatment of Adults With Major Depressive Disorder
This study will examine SPD489 in subjects aged 18-65 with major depressive disorder (MDD) who are taking certain types of antidepressants but continue to have residual depression symptoms.
- Trial name
- NCT01436162
- Testing
- Antidepressant + SPD489 (Lisdexamfetamine dimesylate )
- Where
- 101 sites in United States, Belgium and 9 more
- Volunteers
- 1,105 people
- Sponsor
- Shire
Perinatal Depression, Perinatal Anxiety
Peer Mentor Texting
This study tested whether a peer mentor text message program (called the Nurture program) could help support mental health during pregnancy and after birth.
- Conditions
- Perinatal Depression, Perinatal Anxiety, Parenting Stress
- Trial name
- NCT07380061
- Testing
- Peer mentor texting, Control
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University of Washington
Mental Health Issue, Depression
Developing and Implementing E-psychotherapy Program for Mental Health Challenges in Oncology and Palliative Care
The demand for mental health problems, particularly depression and anxiety, is three times greater in Oncology and Palliative Care Centres than in the general population.
- Conditions
- Mental Health Issue, Depression, Anxiety, Palliative Care
- Trial name
- NCT04664270
- Testing
- e-CBT
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Dr. Nazanin Alavi
Depression, Chronic Disease
Group Self-Management of Depression and Medical Illness
This project addresses the important public health need to reduce ethnic disparities in depression care by pilot testing and refining a culturally tailored, low-cost intervention for improving both depression and general medical…
- Conditions
- Depression, Chronic Disease, Hispanic Americans
- Trial name
- NCT02017262
- Testing
- Self-management group, Enhanced usual care
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Southern California
Breast Cancer, Depression, Anxiety
Mental Health Disparities in Spanish Speaking Latina Breast Cancer Patients
The purpose of the study is to:Translate a mindfulness program into Spanish for Latina patients with breast cancer.Train a community health worker to facilitate the mindfulness program.
- Conditions
- Breast Cancer, Depression, Anxiety, Mindfulness, Sleep Disturbance
- Trial name
- NCT04834154
- Testing
- Mindfulness, Control group
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Stanford University
Shoulder Pain
Examining the Relationship Between Pain, Upper Extremity Functionality and Depression in Individuals With Chronic Shoulder Pain
The aim of the study is to examine the relationship between pain, upper extremity functionality and depression in individuals with chronic shoulder pain.
- Trial name
- NCT06248502
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Tokat Gaziosmanpasa University
Major Depressive Disorder
Study of NSI-189 for Major Depressive Disorder
The study will consist of a screening period and a randomized treatment. Approximately 220 subjects who meet eligibility during the screening period will be randomized to initiate a 12-week, double-blind treatment with NSI-189 80…
- Trial name
- NCT02695472
- Testing
- 80 Milligrams NSI-189, 40 Milligrams NSI-189
- Where
- 13 sites in United States
- Volunteers
- 220 people
- Sponsor
- Neuralstem Inc.
Depression, Hematopoietic and Lymphoid Cell Neoplasm
Using Technology to Optimize Collaborative Care Management of Depression in Urban and Rural Cancer Centers, SCOPE
This study compares the effectiveness of technology-enhanced collaborative care management (t-CoCM) to usual collaborative care management (u-CoCM) in achieving fidelity to processes of care and reducing depression symptoms in…
- Conditions
- Depression, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT05012124
- Testing
- Collaborative care, Interview or Focus Group, Media/technology Intervention with collaborative care
- Where
- 4 sites in United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- University of Washington
Post Traumatic Stress Disorder, Depression
Treatment of Sleep Disturbances in Trauma-affected Refugees
The overall aim of this study is to examine the effects of sleep enhancing treatment in refugees with PTSD.
- Trial name
- PTF5 (NCT02761161)
- Testing
- Mianserin, Imagery Rehearsal Therapy
- Where
- Denmark
- Volunteers
- 241 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Major Depressive Disorders
Relapse Predicting Model for First Episode Depression
Major depressive depression(MDD) is an severe public mental disorders. The purpose of current study is using big data analysis based on clinical features and immunochemistry to investigate and establish an relapse predict model…
- Trial name
- RPM-FED (NCT02942251)
- Testing
- Clinical features and medication, Psycho-social, immunology
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Depression, Anxiety
Testing a Digital Health Intervention App for Depression and Anxiety
Although mobile applications ("apps") for mental health are popular and widely available, little is known about how well they actually help people with common mental health symptoms of depression, anxiety, and stress.
- Trial name
- NCT05373329
- Testing
- Sanvello (app)
- Where
- United States
- Volunteers
- 4,607 people
- Sponsor
- University of Nevada, Las Vegas
Postpartum Depression
Birth Experience During COVID-19 Confinement
Different studies have demonstrated that the absence of companionship during labor and childbirth may be responsible for a negative birth experience, an increased risk of postnatal depression and/or post traumatic stress…
- Trial name
- CONFINE (NCT04348929)
- Testing
- Self-administered questionnaires
- Where
- France
- Volunteers
- 927 people
- Sponsor
- Central Hospital, Nancy, France
Anxiety, Depression
Anxiety With Cancer in the Elderly (ACE): A Cognitive-behavioral Intervention
The purpose of this study is to examine the feasibility and acceptability of and patient adherence to a telephone-administered cognitive-behavioral therapy intervention for anxiety in older adults (65 years and older) with cancer…
- Conditions
- Anxiety, Depression, Quality of Life
- Trial name
- NCT02747160
- Testing
- Managing Anxiety from Cancer (MAC)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Immunodeficiency Virus, Human, Depressive Symptoms
Effectiveness of Nurse-delivered Care for Adherence/Mood in HIV in South Africa
The purpose of this study is to conduct a two-arm effectiveness trial in Cape Town, South Africa of a Xhosa-adapted, nurse-delivered, cognitive behavioral therapy (CBT) treatment for depression and adherence, integrated into the…
- Trial name
- NCT02696824
- Testing
- Cognitive Behavioral Therapy for Adherence and Depression
- Where
- 3 sites in United States, South Africa
- Volunteers
- 161 people
- Sponsor
- University of Miami
Major Depressive Disorder, Treatment Resistant Depression
Ketamine Augmentation of ECT in Treatment-Resistant Depression
This is a randomized, double-blind, placebo-controlled phase 3 clinical trial evaluating the additive effect of intravenous ketamine in combination with electroconvulsive therapy (ECT) in patients with treatment-resistant major…
- Trial name
- Ketamina (NCT07088380)
- Testing
- Ketamine Hydrochloride
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Università Vita-Salute San Raffaele
Schizophrenia, Bipolar Disorder
Medication Adherence in Older Adults With Serious Mental Illness
The goal of this pilot study is to learn about how well older people with serious mental illness (including schizophrenia, schizoaffective disorder, bipolar disorder, major depression) follow prescribed medication regimens, and…
- Conditions
- Schizophrenia, Bipolar Disorder, Depression
- Trial name
- NCT00224380
- Testing
- Using Medications Effectively
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Major Depressive Disorder
Relative Bioavailability (RBA) Study of LY03005 vs Pristiq®
The objective of this study is to evaluate relative bioavailability between 80 mg LY03005 oral tablets and 50 mg Pristiq® oral tablets after a single dose of each drug in a cross-over 2-period design under fasting condition in…
- Trial name
- NCT03357796
- Testing
- LY03005, Pristiq
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Luye Pharma Group Ltd.
Frailty Syndrome
TrackFrailty Project
The TRACKFRAILTY project aims to answer the following main research questions: i) What is the prevalence of physical frailty in individuals living in residential care facilities (RCF) from Portugal's Cova da Beira subregion…
- Trial name
- TrackFrailty (NCT06812286)
- Testing
- Less-volume, More-volume, Control
- Where
- 6 sites in Portugal
- Volunteers
- 45 people
- Sponsor
- University of Beira Interior
Current Major Depressive Disorder
Predictive Nature of Total Cholesterol Threshold: Possible Link to Suicidal Behavior
Suicidal behavior (SB) is a public health problem. The clinical model currently admitted to the understanding of SB is a stress vulnerability model, but so far, all scientific works has no clinical application.
- Trial name
- NCT02847741
- Testing
- patient's routine care
- Where
- France
- Volunteers
- 555 people
- Sponsor
- University Hospital, Montpellier
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