Clinical trials: Depressive State
Postmenopausal Depression, Estrogen
Assessment of the Improvement in Cognitive Levels of Postmenopausal Depression Patients by Estrogen
After menopause, there is a certain tendency towards depression, with the risk of developing depression being about 3 to 4 times higher than before menopause.
- Trial name
- NCT06358014
- Testing
- Fematon (estradiol/estradiol-norethindrone acetate combination tablet package)+SSRIs, SSRIs
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xiao Wang
Insomnia, Depression
Evaluating the Impact of Digital Behavioral Interventions to Address Insomnia and Depression in Breast Cancer Survivors Using an Adaptive Design
Co-occurring symptoms of insomnia and depression is very common in breast cancer survivors, and it is critical that scalable and easily accessible digital behavioral interventions are made available.
- Trial name
- NCT07721064
- Testing
- Digital Insomnia Program, Digital Mental Health Program, Psychoeducation
- Where
- United States
- Volunteers
- 747 people
- Sponsor
- University of Virginia
Depression - Major Depressive Disorder, Insomnia
Auditory Stimulation for Insomnia and Depression
The goal of this clinical trial is to determine if alpha phase-locked auditory stimulation can improve sleep in people with insomnia and depression.
- Trial name
- NCT07553364
- Testing
- Alpha phase-locked auditory stimulation
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Parkinson Disease, Depression
Probiotic Treatment for Depression and Associated Mood Disorders in Parkinson's Disease
This study evaluates the use of an oral multi-strain probiotic in the treatment of depression in individuals with Parkinson's Disease.
- Conditions
- Parkinson Disease, Depression, PARKINSON DISEASE (Disorder)
- Trial name
- ProD (NCT05568498)
- Testing
- Probiotic
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Amyotrophic Lateral Sclerosis
Repetitive Transcranial Magnetic Stimulation as Therapy for Depression in Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of central and peripheral motor neurons. ALS leads to death usually within 3 to 5 years from the onset of the symptoms.
- Trial name
- NCT03892863
- Testing
- active repetitive transcranial magnetic stimulation
- Where
- Poland
- Sponsor
- Jagiellonian University
Huntington Disease
A Pilot Evaluation of Mindfulness-based Cognitive Therapy for People With Huntington's Disease
This is a pilot study to see whether mindfulness-based cognitive therapy, which is a type of psychological therapy, is able to improve the psychological wellbeing of people who have the gene for Huntington's disease.
- Trial name
- NCT02464293
- Testing
- Mindfulness-based cognitive therapy
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Lancaster University
Depression
Neuronavigated TBS in Depression
In this randomized controlled trial we will treat 80 patients with depression with intermittent theta burst stimulation in two parallel arms.
- Trial name
- neuronaviTBS (NCT03953521)
- Testing
- intermittent Theta burst stimulation
- Where
- Germany
- Volunteers
- 37 people
- Sponsor
- University of Regensburg
ART, Hiv
Strengthening Families Living With HIV in Kenya
This study seeks to use a group-based microfinance/internal lending model to develop social capital among people with HIV in Kenya.
- Conditions
- ART, Hiv, Trust, Depression, Anxiety
- Trial name
- NCT04588883
- Testing
- Kuja Pamoja - HIV
- Where
- Kenya
- Volunteers
- 843 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Postpartum Depression, Internet-based Intervention
Feasibility Study: Self-guided iCBT for Mothers With Postpartum Depression.
The purpose of this study is to conduct a feasibility study to test the study procedure and a newly developed self-guided internet-based cognitive behavioral therapy program for mothers with postpartum depression.
- Trial name
- NCT06569875
- Testing
- iCARE
- Volunteers
- 20 people
- Sponsor
- University of Southern Denmark
Rheumatoid Arthritis, Psoriatic Arthritis
Mindfulness Based Stress Reduction in Rheumatic Diseases
This study will assess the mental health and clinical benefits of Mindfulness Based Stress Reduction (MBSR) in patients with rheumatic disease who have anxiety or depression.
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Scleroderma
- Trial name
- MBSR (NCT03411057)
- Testing
- Mindfulness Based Stress Reduction (MBSR), Control
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University
Depression, Anxiety, Emotional Disorders
Weekly Dynamics of Psychopathological and Symptom Networks During Mindfulness-Based Interventions for Emotional Distress
The goal of this clinical study is to learn how Mindfulness Intervention for Emotional Distress (MIED) helps people with emotional distress and how their symptoms and psychological patterns change over time.
- Trial name
- NCT07280481
- Testing
- Mindfulness Intervention for Emotional Distress (self-guided version)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Peking University
Postpartum Depression
A Long-Term Study of Patient-Reported Changes in Postpartum Depression Symptoms in People Starting Zuranolone
In this study, researchers will learn how postpartum depression symptoms may change after people first start taking zuranolone. This is a drug available for doctors to prescribe for people with postpartum depression, also known…
- Trial name
- NCT07398469
- Testing
- Zuranolone
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Biogen
Military Personnel, Family Members
Telephone Support During Overseas Deployment for Military Spouses
Deployment impacts both service member and family, and the cost can be high. Spouses' reactions to deployment may include emotional distress, loneliness, anticipatory fear or grief, somatic complaints, and depression.
- Conditions
- Military Personnel, Family Members, Resilience, Psychological, Deployment
- Trial name
- NCT01828983
- Testing
- Telephone support groups, Education webinars
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Memphis VA Medical Center
Depression, Anxiety
Effect of the MindUP Program on Depression, Anxiety, and Stress in Pakistani Orphan Adolescents
This study evaluates the effectiveness of the MindUP mindfulness-based program in reducing depression, anxiety, and stress among orphan adolescents in Pakistan.
- Conditions
- Depression, Anxiety, Stress
- Trial name
- MINDUP-PAK (NCT07468994)
- Testing
- MindUP Program
- Where
- Pakistan
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Quaid-e-Azam University
Depression
Latina Adolescent Depression Treatment Study
Despite experiencing higher rates of depressive symptoms and similar rates of Major Depressive Disorder (MDD), Latina (female) adolescents in the U.S.
- Trial name
- NCT04164537
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Duke University
Diaper Dermatitis, Urinary Tract Infections
Intervention to Reduce Diaper Need and Increase Use of Pediatric Preventive Care
Well-child care is the primary source of preventative health care for children. These visits provide an opportunity for physicians to assess an infant's biomedical health, development, and behavior, as well as help ensure timely…
- Conditions
- Diaper Dermatitis, Urinary Tract Infections, Infection, Depressive Symptoms
- Trial name
- NCT03490045
- Testing
- Diaper Incentive, Conditional Cash Transfer Condition
- Where
- 2 sites in United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Yale University
Morbid Obesity
Impact of Bariatric Surgery on Female Sexual Function and Sex Hormones
The goal of this observational study is to learn about how weight loss surgery (also called bariatric surgery) affects sexual function and sex hormone levels in women with severe obesity.
- Trial name
- NCT07446972
- Testing
- Sleeve Gastrectomy, Gastric Bypass
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Depressive Disorder, Depressive Disorder, Major
Synaptic Imaging and Network Activity in Treatment Resistant Depression
The main aim of this research is to explore the effects that ketamine has on the functional connectivity of the brain in participants with treatment resistant depression (TRD).
- Conditions
- Depressive Disorder, Depressive Disorder, Major, Depressive Disorder, Treatment-Resistant, Bipolar Disorder
- Trial name
- SIGNATURE (NCT05870501)
- Testing
- Ketamine, Midazolam
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- King's College London
Caregiver Burden, Depressive Symptoms
Cluster RCT of Cognitive Behavioral Therapy to Support Caregivers of Older Adults in Hong Kong
The goal of this cluster randomized controlled trial study is to compare the effectiveness of a novel psychosocial intervention based on Cognitive Behavioral Therapy, lifestyle intervention and effective communication skills in…
- Conditions
- Caregiver Burden, Depressive Symptoms, Quality of Life, Self Efficacy
- Trial name
- NCT06473012
- Testing
- Cognitive Behavioral Therapy for Caregivers of Older Adults, Control intervention for Caregivers of Older Adults
- Where
- Hong Kong
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Symptoms of Depression, Symptoms of Anxiety
Mindfulness-Based Cognitive Therapy for Depression and Anxiety
About 10-20% of older patients in primary care suffer from symptoms of depression and/or anxiety. Depression and anxiety are associated with higher rates of cognitive decline, lower quality of life, increased medical comorbidity…
- Trial name
- NCT02777905
- Testing
- Mindfulness Based Cognitive Therapy
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Lady Davis Institute
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.