Clinical trials: Depressive State
Acute Stress Disorder, Anxiety
GASA-CIR Trail (Guidance and the Symptoms of Acute Stress and Anxiety in Critically Ill Patients Relatives in Intensive Care Unit)
A randomized clinical trial 1:1 among relatives of patients admitted to an intensive care unit, the intervention group will be composed by family members who receive a printed brochure and will be encouraged to visit a website…
- Conditions
- Acute Stress Disorder, Anxiety, Depression
- Trial name
- GASA-CIR (NCT03812458)
- Testing
- website and brochure
- Where
- Brazil
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Depression, Adolescent Behavior
Volunteering as an Intervention to Reduce Depression Among Adolescents
The purpose of the present study is to test in a preliminary manner an innovative strategy for treating depression among adolescents (alongside existing therapy) using community volunteerism.
- Conditions
- Depression, Adolescent Behavior, Depressive Symptoms
- Trial name
- NCT03816215
- Testing
- Volunteer experience
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Wake Forest University Health Sciences
Post Intensive Care Syndrome, Depression
Companion Dog Walking for ICU Survivor Health
The goal of this clinical trial is to determine the feasibility and acceptability of a randomized controlled trial comparing a pet dog walking intervention to an attention control education intervention in adult intensive care…
- Conditions
- Post Intensive Care Syndrome, Depression, Anxiety, Quality of Life
- Trial name
- POOCH (NCT05820308)
- Testing
- Companion Dog Walking, Attention Control Group
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- University of Missouri, Kansas City
Bipolar Depression
Magnetic Resonance Imaging Study of Lisdexamfetamine for Bipolar Depression
There have been reports that stimulants may be effective for bipolar depression without triggering mania. This study will examine whether lisdexamfetamine can improve depressive symptoms over the course of eight weeks.
- Trial name
- NCT01051440
- Testing
- Lisdexamfetamine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
Major Depressive Disorder
Deep rTMS for Depression in Older Adults
This study aims to: (1) assess the feasibility and tolerability of two active dTMS coils - H4 and H7 - in older adults with depression; and (2) clinical response measured by change from baseline on the Hamilton Depression Rating…
- Trial name
- NCT05855850
- Testing
- Brainsway H4-Coil Deep TMS System, Brainsway H7-Coil Deep TMS System
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Postintensive Care Syndrome, Family Members
Family Support Intervention in Intensive Care Units
Background: Family members of critically ill patients face considerable uncertainty and distress during their close other's intensive care unit (ICU) stay, with about 20-60% of family members experiencing post-traumatic distress…
- Conditions
- Postintensive Care Syndrome, Family Members, Quality of Life, Depression, Anxiety
- Trial name
- FICUS (NCT05280691)
- Testing
- Family Support Intervention (FSI)
- Where
- 12 sites in Switzerland
- Volunteers
- 885 people
- Sponsor
- Rahel Naef
Anxiety, Depression
The Effects of Animal Assisted Therapy in Outpatient Psychiatry Clinics
This study will examine whether a session of animal-assisted therapy reduces anxiety levels and improves long-term clinical outcomes of outpatient psychiatric patients in regard to their Generalized Anxiety Disorder (GAD-7)…
- Conditions
- Anxiety, Depression, Psychiatric or Mood Diseases or Conditions
- Trial name
- NCT05326074
- Testing
- Animal assisted therapy cohort
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
LGBTQ, Racial Disparities
Lakota Family Acceptance Project
The goal of this open pilot trial (OPT) is to develop a Lakota-adapted Family Acceptance Project (LFAP) for Indigenous 2SLGBTQ+ youth and their caregivers.
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- L-FAP OPT (NCT07326748)
- Testing
- Adapted Lakota Family Acceptance Program
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Depressive Symptoms
Nurse-Led Interprofessional Mental Health Promotion Intervention for Older Home Care Clients
Objective: The objective of this study is to evaluate the feasibility, acceptability and effectiveness of a 6-month nurse-led, interprofessional mental health promotion intervention aimed at older home care clients with…
- Trial name
- NCT01407926
- Testing
- Nurse-Led Mental Health Promotion Intervention
- Where
- Canada
- Volunteers
- 142 people
- Sponsor
- McMaster University
Self Injurious Behavior, Self Injurious Behavior Without Suicidal Intent
Examining the Effectiveness of a Brief Therapeutic Intervention for Reducing Self-Harm Among Adolescents
Non-suicidal self-injury (NSSI), defined as deliberate self-inflicted destruction of body tissue without intent to die, is particularly prevalent during mid-adolescence, with prevalence estimated around 16-22% in community…
- Trial name
- NCT07913425
- Testing
- Cutting Down Program - a three-month cognitive-behavioral psychotherapy focused on reducing self-injury urges and behaviors in adolescents
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- University of Haifa
Depression
Effects of an Innovative TCM-based Tui Jing Therapy on Psychological and Neurophysiological Functions in Depression
Background: Mental disorders are recognized as a major cause of disability and disease burden across the lifespan. Gua Sha is believed to improve mental health and sleep quality significantly.
- Trial name
- TJ (NCT07449676)
- Testing
- manual therapy: Tui Jing therapy
- Where
- Hong Kong
- Volunteers
- 64 people
- Sponsor
- The Hong Kong Polytechnic University
Depression
Smartwatch-supported Internet-delivered Intervention for Depression
The current study seeks to investigate the acceptance of the use of a smartwatch in an internet-delivered Cognitive Behavioural Therapy (CBT) based intervention for depression.
- Trial name
- NCT04568317
- Testing
- Space from Depression, Mood Monitor watch app
- Where
- United Kingdom
- Volunteers
- 71 people
- Sponsor
- Silver Cloud Health
Depression Mild, Depression Moderate
Neural Mechanisms of Meditation Training in Healthy and Depressed Adolescents: An MRI Connectome Study PART 2
The primary objective will be to study changes in putamen connectivity and depression severity in depressed teens with meditation training.
- Conditions
- Depression Mild, Depression Moderate, Depression, Teen
- Trial name
- NCT05267340
- Testing
- TARA, Psycho-Education
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, San Francisco
Depression, Anxiety
Chinese Herb for the Treatment of Depression and Anxiety Disorders
Anxiety and depression are currently among the ten most important public health concerns, and in recent years, have reached epidemic proportions.
- Trial name
- NCT03323697
- Testing
- SZ-05, Escitalopram Pill
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Mazra Mental Health Center
Major Depressive Disorder
Effect of Amygdala Neurofeedback on Depressive Symptoms and Processing Biases
The purpose of this study is to determine whether upregulating the left amygdala during positive autobiographical memory recall via real time functional magnetic resonance imaging neurofeedback will lead to an improvement in…
- Trial name
- NCT02079610
- Testing
- real-time fMRI neurofeedback: Amygdala, real-time fMRI neurofeedback: HIPS
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Treatment Resistant Depression
Neurobiological Analyses Within the FORESEE III Study
In this observational, non-invasive clinical study different neurobiological analyses will be performed in a group of patients with severe treatment resistant major depression participating in an efficacy study of deep brain…
- Trial name
- NCT04021823
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Suicide, Attempted, Mood Disorder
Functional Imaging of Psychic Pain
Suicidal behaviour (SB) represents a major public health problem, costing life in more that one million people every year worldwide.
- Trial name
- NCT01493323
- Testing
- Assessment of personality traits, Assessment of suicidal act, Assessment of depression
- Where
- France
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Depression, Hepatitis C
Improving Quality of Life for Veterans Undergoing Interferon Treatment
The purpose of this study is to evaluate a group psychotherapy intervention and a telehealth intervention for veterans undergoing interferon treatment for the hepatitis C virus.
- Trial name
- NCT00117559
- Testing
- Telehealth Treatment
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- US Department of Veterans Affairs
Major Depressive Disorder, Alzheimer Disease
Home-based Neuromodulation to Target Depression And Memory Symptoms in Older Adults
This project aims to explore the feasibility and effects of a symptom-specific, brain-circuit-based, home-based neuromodulation therapy for addressing mood and memory symptoms in older adults with major depressive disorder (MDD)…
- Conditions
- Major Depressive Disorder, Alzheimer Disease, Dementia, Nervous System Diseases
- Trial name
- NCT05976659
- Testing
- Transcranial direct current stimulation (tDCS); Transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hebrew SeniorLife
Substance Use Disorder (SUD)
Auricular Vagal Neuromodulation for Depression and Anxiety in Substance Use Disorder
This pilot study will evaluate whether home-based auricular vagal neuromodulation therapy (AVNT) is practical, acceptable, and well tolerated for adults receiving treatment for substance use disorder.
- Trial name
- NCT07814755
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Daisy Thompson-Lake
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