Clinical trials: Depressive State
Cardiovascular Diseases, Heart Diseases
University of North Carolina Alumni Heart Study
To continue surveillance of the participants in the University of North Carolina Alumni Heart Study, which tests the hypothesis that hostility and related psychosocial factors are involved in the pathogenesis of coronary heart…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Depression
- Trial name
- NCT00005398
- Testing
- There is no intervention
- Where
- United States
- Volunteers
- 6,340 people
- Sponsor
- Duke University
PostTraumatic Stress Disorder
Effectiveness of Basic Body Awareness Therapy in Post-traumatic Stress Disorders: A Randomized Clinical Trial
The aim of this randomized controlled clinical trial is to assess the effectiveness of Basic Body Awareness Therapy online in patients' survivors of Covid-19, health workers and women suffering from gender based violence…
- Trial name
- BATEP (NCT04396314)
- Testing
- Basic Body Awareness Therapy, Psychological treatment
- Volunteers
- 54 people
- Sponsor
- Universitat de Lleida
Depression, Anxiety Disorders
Primary Care Group Therapy for Depression/Anxiety for Women in Petropolis
This is a randomized controlled trial comparing two groups: 1) Enhanced usual care and 2) Enhanced usual care plus group psychological intervention.
- Trial name
- NCT03586921
- Testing
- Psychosocial Group Intervention, Enhanced Usual Care
- Volunteers
- 340 people
- Sponsor
- Rio de Janeiro State University
Spinal Cord Injuries, Depression
Guided Internet Delivered Cognitive-Behaviour Therapy for Persons With Spinal Cord Injury: A Feasibility Trial
In Canada the prevalence of spinal cord injury (SCI) is approximately 85,556, with incidence rates of traumatic and non-traumatic SCI at 1,785 and 2,286 cases per year, respectively.
- Conditions
- Spinal Cord Injuries, Depression, Anxiety
- Trial name
- NCT03457714
- Testing
- Guided ICBT for persons with Spinal Cord Injury, Survey
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Regina
Young Adult
The Effect of Smartphone Addiction on Physical Activity and Depression in University Students
This study was planned considering that young people with smartphone addiction are depressed and their physical activity is significantly reduced.
- Trial name
- NCT04606277
- Testing
- Smartphone addiction scale, physical activity scale and depression questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Depression, Major Depressive Disorder
Noninvasive Physiologic Sensors to Assess Depression
This project aims to use sensors to monitor physiological signals, sleep patterns, vocal characteristics, activity, location and phone usage in study patients with depression who are receiving standard treatment (compared with…
- Trial name
- NCT02568865
- Testing
- Physiological Sensors, Sleep Monitoring Device, Vocal Monitoring
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Maternal Depression
Participatory Intervention to Reduce Maternal Depression and Under Five Child Morbidity
To test the efficacy of an innovative affordable intervention program that can be used by non-specialists, including mothers and lady health workers with minimal training in low resource countries such as Pakistan
- Trial name
- ROSHNI (NCT02047357)
- Testing
- Learning Through Play Plus
- Where
- Pakistan
- Volunteers
- 774 people
- Sponsor
- Pakistan Institute of Living and Learning
Depression, Loneliness
VOICES Socials for Older Veterans With Depression
VOICES Veterans Socials (VS) support Veterans in the community through weekly social groups. Veterans socials have the potential to improve social functioning, mental health symptoms, and create lasting social support.
- Conditions
- Depression, Loneliness, Isolation
- Trial name
- NCT06145334
- Testing
- Veterans Social
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Treatment Resistant Depression, Depression
Glutamate Emotion Memory Study
Clinical depression often includes a pessimistic view of things which have happened in the past and an impairment in the ability to experience pleasure or looking forward to things.
- Conditions
- Treatment Resistant Depression, Depression, Major Depressive Disorder
- Trial name
- GEMS (NCT05809609)
- Testing
- Ketamine Hydrochloride
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Oxford
Depression, Anxiety
Treating Common Mental Disorders in Women in Mozambique by Addressing Intimate Partner Violence in Couples
Adapting mental health treatments to address modifiable interpersonal problems has the potential to improve and sustain outcomes in low-resource settings where treatment gaps persist.
- Conditions
- Depression, Anxiety, PTSD, Intimate Partner Violence
- Trial name
- NCT06252909
- Testing
- Interpersonal Psychotherapy for Couples, Interpersonal Psychotherapy (Individual)
- Volunteers
- 108 people
- Sponsor
- New York State Psychiatric Institute
Major Depressive Disorder, Treatment Resistant Depression
MAO-B Occupancy in Depressed Patients
The study is looking at assessing monoamine oxidase B (MAO-B) occupancy in depressed patients before and after medication treatment using positron emission tomography (PET) scan.
- Trial name
- MOCP (NCT04841798)
- Testing
- [11C]SL25.1188 PET radiotracer
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Centre for Addiction and Mental Health
Traumatic Stress Disorder
The Effect of Flash Technique Via Self-Therapy App on Depression, Anxiety, and Traumatic Symptoms
EMDR is a psychotherapy method utilized for treating psychological traumas, with the Flash technique being one of its quickest and most effective methods.
- Trial name
- NCT06419387
- Testing
- Self-Therapy Mobile App, Psycho-education Videos
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Academy of Therapeutic Sciences, Turkey
Alzheimer's Disease
Early Counseling and Support for Alzheimer's Disease Caregivers
This randomized trial evaluates the efficacy of counselling for reducing anxiety and depression in caregivers of patients with dementia.
- Trial name
- D_CareGiver (NCT02685787)
- Testing
- Psychosocial Intervention, Educational Intervention on AD
- Where
- Italy
- Volunteers
- 230 people
- Sponsor
- Azienda Sanitaria Locale N.1 dell'Umbria
Dementia, Depression
Pilot Study of Asynchronous and Synchronous Telepsychiatry for Skilled Nursing Facilities
Specific Aims: This study aims to assess the acceptability of asynchronous telepsychiatry (ATP) and synchronous (STP) in rural Skilled Nursing Facility (SNF) population, in a 12-month randomized controlled trial.
- Conditions
- Dementia, Depression, Mood Disorder, Anxiety Disorder
- Trial name
- NCT02537093
- Testing
- Psychiatric Consultation
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Depression in Remission
Mechanisms of Change of Positive Interventions in Reducing Vulnerability for Depression
The purpose of this study is to understand the effects of mindfulness and fantasizing in reducing perseverative cognition underlying vulnerability for depression.
- Trial name
- MINDCOG (NCT06145984)
- Testing
- Mindfulness, Positive Fantasizing
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Depressive Symptoms
Mindfulness-Based Cognitive Therapy (MBCT) and Cognitive Behavioral Therapy (CBT) for Depression in Diabetes Patients
The purpose of this study is to determine whether mindfulness-based cognitive therapy (MBCT)and cognitive behavioral therapy (CBT)are effective in reducing depressive symptoms in patients with diabetes.
- Trial name
- NCT01630512
- Testing
- Mindfulness-Based Cognitive Therapy (MBCT), Cognitive Behavioral Therapy (CBT)
- Where
- Netherlands
- Volunteers
- 94 people
- Sponsor
- University Medical Center Groningen
Bipolar Disorder, Bipolar Depression
Efficacy of Convulsive Therapies for Bipolar Depression
This trial aims to assess the efficacy and tolerability of Magnetic Seizure Therapy (MST) as an alternative to electroconvulsive therapy (ECT) for Bipolar Disorder (BD).
- Conditions
- Bipolar Disorder, Bipolar Depression, Bipolar I Disorder, Bipolar II Disorder
- Trial name
- CORRECT-BD (NCT03641300)
- Testing
- Magnetic Seizure Therapy (MST), Electroconvulsive Therapy (ECT)
- Where
- 3 sites in Canada
- Volunteers
- 76 people
- Sponsor
- Centre for Addiction and Mental Health
Treatment Resistant Major Depression Disorder
DBS of the Habenula for Treatment- Resistant Major Depression
The habenula(Hb) is an epithalamic structure located at the center of the dorsal diencephalic conduction system, a pathway involved in linking forebrain to midbrain regions.
- Trial name
- NCT03347487
- Testing
- Deep brain stimuation system implantation
- Where
- China
- Volunteers
- 7 people
- Sponsor
- Ruijin Hospital
Depression, Anxiety, Adherence, Patient
Medication Review in Women With Depression and Anxiety
This study sought to assess the impact of the MMR service on identifying and resolving TRPs, improving adherence, depression and anxiety scores in females diagnosed with depression and anxiety in Jordan
- Trial name
- NCT04082871
- Testing
- Medication management review
- Volunteers
- 73 people
- Sponsor
- Applied Science Private University
Depression
Computer-based Treatment of Dysfunctional Beliefs in Depressive Inpatients
The aim of the present study is to investigate whether confronting depressive patients with their dysfunctional core beliefs via a computer program results in a reduction of the patients' dysfunctional beliefs.
- Trial name
- NCT03389464
- Testing
- computer-based confrontation with dysfunctional beliefs
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Regensburg
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